PCR-Positivity in harvested bone marrow predicts relapse after transplantation with autologous purged bone marrow in children in second remission of precursor B-cell acute leukaemia

British Journal of Haematology

Volumn 96, Issue 2, 1997, Pages 395-402

  Vervoordeldonk, Susan F ^a,e   Merle, Pauline A ^a   Behrendt, Henk ^b   Steenbergen, Eric J ^a   Van Den Berg, Henk ^b   Van Wering, Elisabeth R ^c   Von Dem Borne, Albert E G Kr ^d   Van Der Schoot, C Ellen ^a,d   Van Leeuwen, Eleonore F ^b   Slaper Cortenbach, Ineke C M ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b EMMA CHILDREN S HOSPITAL   (Netherlands)

^c Dutch Childhood Leukaemia Stud Grp   (Netherlands)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e CENTRAL LABORATORY   (Netherlands)

Author keywords

acute lymphoblastic leukaemia; autologous bone marrow transplantation; polymerase chain reaction; purging

Indexed keywords

ADOLESCENT; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; B CELL LEUKEMIA; CANCER RECURRENCE; CHILD; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; FEMALE; HUMAN; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 8044234378     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.d01-2018.x     Document Type: Article

References (35)

1. Bast. C., De Fabritiis, P., Lipton, J., Gelber, R., Maver, C., Nadler, L., Sallan, S. & Ritz, J. (1985) Elimination of malignant clonogenic cells from human bone marrow using multiple monoclonal antibodies and complement. Cancer Research, 45, 499-503.
2. Behrendt, H., van Leeuwen, E.F., Schuwirth, C., Verkes, R.J., Hermans, J., Van der Does-Van den Berg, A. & van Wering, E.R. (1990) Bone marrow relapse occurring as first relapse in children with acute lymphoblastic leukaemia. Medical and Pediatric Oncology, 18, 190-196.
3. Billett, A.L., Kornmehl, E., Tarbell, N.J., Weinstein, H.J., Gelber, R.D., Ritz, J. & Sallan, S.E. (1993) Autologous bone marrow transplantation after a long first remission for children with recurrent acute lymphoblastic leukemia. Blood, 81, 1651-1657.
4. Brenner, M.K., Rill, D.R., Moen, R.C., Krance, R.A., Mirro, J.J., Anderson, W.F. & Ihle, J.N. (1993) Gene-marking to trace origin of relapse after autologous bone-marrow transplantation. Lancet, 341, 85-86.
5. Campana, D. & Pui, C. (1995) Detection of minimal residual disease in acute leukemia: methodological advances and clinical significance. Blood, 85, 1416-1434.
6. Culbert, S.J., Shuster, J.J., Land, V.J., Wharam, M.D., Thomas, P.R., Nitschke, R., Pinkel, D. & Vietti,T.J. (1991) Remission induction and continuation therapy in children with their first relapse of acute lymphoid leukaemia: a Pediatric Oncology Group study. Cancer, 67, 37-42.
7. Deisseroth, A.B., Zu, Z., Claxton, D., Hanania, E.G., Fu, S., Ellerson, D., Goldberg, L., Thomas, M., Janicek, K., Anderson, W.F., Hester, J., Korbling, M., Durett, A., Moen, R., Berenson, R., Heimfeld, S., Hamer, J., Calvert, L., Tibbits, P., Talpaz, M., Kantarjian, H., Champlin, R., Reading, C. (1994) Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML. Blood, 83, 3068-3076.
8. Garcia, J., Punti, C., Picon, M., Tigues, D., Amill, B., Canals, C., Ayats, R., Ramon, I., Gilabert, R., Sierra, J., Badell, I., Brunet, S., Ortega, J., Valls, A. & Granena, A. (1994) Bone marrow purging in acute lymphoblastic leukemia: biological and clinical features. Journal of Hematotherapy, 3, 203-211.
9. Gilmore, M.J., Hamon, M.D., Prentice, H.G., Katz, F., Slaper Cortenbach, I.C., Hunter, A.E., Gandhi, L., Brenner, M.K., Hoffbrand, A.V., Mehta, A.B., Secker-Walker, L.M., Skeggs, D. & Collis, C.H. (1991) Failure of purged autologous bone marrow transplantation in high risk acute lymphoblastic leukemia in first complete remission. Bone Marrow Transplantation, 8, 19-26.
10. Gribben, J.G., Freedman, A.S., Neuberg, D., Roy, D.C., Blake, K.W., Woo, S.D., Grossbard, M.L., Rabinowe, S.N., Coral, F., Freeman, G.J., Ritz, J. & Nadler, L.M. (1991) Immunologic purging of marrow assessed by PCR before autologous bone marrow transplantation for B-cell lymphoma. New England Journal of Medicine, 325, 1525-1533.
11. Gribben, J.G. & Nadler, L.M. (1995) Purging of bone marrow. Biologic Therapy of Cancer (ed. by V. T. DeVita, S. Hellman and S. A. Rosenberg), p. 596. J. B. Lippincott Company, Philadelphia.
12. Hann, I.M., Morris Jones, P.H. & Evans, D.I.K. (1977) Discrepancy of bone-marrow aspirations in acute lymphoblastic leukaemia in relapse, Lancet, i, 1215-1216.
13. Henze, G., Fengler, R., Hartmann, R., Kornhuber, B., Janka Schaub, G., Niethammer, D. & Riehm, H. (1991) Six-year experience with a comprehensive approach to the treatment of recurrent childhood acute lymphoblastic leukemia (ALL-REZ BFM 85): a relapse study of the BFM group, Blood, 78, 1166-1172.
14. Kersey, J.H., Weisdorf, D., Nesbit, M.E., LeBien, T.W., Woods, WG., McGlave, P.B., Kim, T., Vallera, D.A., Goldman, A.I., Bostrom, B., Hurd, D. & Ramsay N.K. (1987) Comparison of autologous and allogeneic bone marrow transplantation for treatment of high-risk refractory acute lymphoblastic leukemia. New England Journal of Medicine, 317, 461-467.
15. Lansdorp, P.M., Aalberse, R.C., Bos, R., Schutter, W.G. & van Bruggen, E.F.J. (1986) Cyclic tetramolecular complexes of monoclonal antibodies: a new type of cross-linking reagent. European Journal of Immunology, 16, 679.
16. Lazarus, H.M., Rowe, J.M. & Goldstone, A.H. (1993) Does in vitro bone marrow purging improve the outcome after autologous bone marrow transplantation? Journal of Hematotherapy, 2, 457-466.
17. Martens, A.C., Schultz, E.W. & Hagenbeek, A. (1987) Nonhomogeneous distribution of leukemia in the bone marrow during minimal residual disease. Blood, 70, 1073-1078.
18. Moussalem, M., Esperou Bourdeau, H., Devergie, A., Baruchel, A., Ribaud, P., Socie, G., Parquet, N., Traineau, R., Hirsch, I., Schaison, G. & Gluckman, E. (1995) Allogeneic bone marrow transplantation for childhood acute lymphoblastic leukemia in second remission: factors predictive of survival, relapse and graft-versus-host disease. Bone Marrow Transplantation, 15, 943-947.
19. Murgo, A.J., Weinberger, B.B. & Johnson, J.R. (1992) Immunologic purging of marrow assessed by polymerase chain reaction. New England Journal of Medicine, 326, 1163.
20. Negrin, R.S. (1992) Use of the polymerase chain reaction for the detection of tumor cell involvement of bone marrow and peripheral blood: implications for purging. Journal of Hematotherapy, 1, 361-368.
21. Pui, C. (1995) Childhood leukemias. New England Journal of Medicine, 332, 1618-1630.
22. Reiter, A., Schrappe, M., Ludwig, W., Hiddemann, W., Sauter, S., Henae, G., Zimmermann, M., Lampert, F., Havers. W., Niethammer, D., Odenwald, E., Ritter, J., Mann, G., Welte, K., Gadner, H. & Riehm, H. (1995) Chemotherapy in 998 unselected childhood acute lyphoblastic leukemia patients: results and conclusions of the multicenter trial ALL-BFM 86. Blood, 84, 3122-3133.
23. Rill, D.R., Santana, V.M., Roberts, W.M., Nilson, T., Bowman, L.C., Krance, R.A., Heslop, H.E., Moen, R.C., Ihle, J.N. & Brenner, M.K. (1994) Direct demonstration that autologous bone marrow transplantation for solid tumours can return a multiplicity of tumorigenic cells. Blood. 84, 380-383.
24. Saiki, RK., Scharf, S., Faloona, F., Mullis, KB., Horn, GT., Erlich, H.A. & Arnheim, N. (1985) Enzymatic amplification of β-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science, 230, 1350-1354.
25. Sallan, S.E., Niemeyer, C.M., Billett, A.L., Lipton, J.M., Tarbell, N.J., Gelber, R.D., Murray, C., Pittinger, T.P., Wolfe, L.C., Bast, R.C.J. & Ritz, J. (1989) Autologous bone marrow transplantation for acute lymphoblastic leukaemia. Journal of Clinical Oncology, 7, 1594-1601.
26. Seriu, T., Yokota, S., Nakao, M., Misawa, S., Takaue, Y., Koizumi, S., Kawai, S. & Fujimoto, T. (1995) Prospective monitoring of minimal residual disease during the course of chemotherapy in patients with acute lymphoblastic leukemia, and detection of contaminating tumor cells in peripheral blood stem cells for autotransplantation. Leukemia, 9, 615-623.
27. Simonsson, B., Burnett, A.K., Prentice, H.G., Hann, I.H., Brenner, M.K., Gibson, B., Grob, J.P., Lonnerholm, G., Morrison, A., Smedmyr, B., Todd, A., Oberg, G., Gilmore, M., Campana, D. & Totterman, Th. (1989) Autologous bone marrow transplantation with monoclonal antibody purged marrow for high risk acute lymphoblastic leukemia. Leukemia, 3, 631-636.
28. Slaper-Cortenbach, I.C.M., Admiraal, L.G., van Leeuwen, E.F., Kerr, J.M., von dem Borne, A.E.G.Kr. & Tetteroo, P.A.T. (1990) Effective purging of bone marrow by a combination of immunorosette depletion and complement lysis. Experimental Hematology, 18, 49-54.
29. Steenbergen, E.J., Verhagen, O.J.H.M., van Leeuwen, E.F., van den Berg, H., Behrendt, H., Slater, R.M., von dem Borne, A.E.G.Kr. & van der Schoot, C.E. (1995a) Prolonged persistence of PCR-detectable minimal residual disease after diagnosis or first relapse predicts poor outcome in childhood B-precursor acute lyniphoblastic leukemia. Leukemia, 9, 1726-1734.
30. Steenbergen, E.J., Verhagen, O.J.H.M., Van Leeuwen, E.F., van den Berg, H., Behrendt, H., Von dem Borne, A.E.G.Kr. & Van der Schoot, C.E. (1995b) IgH/TCRd PCR oligonucleotide liquid hybridization, a fast and sensitive assay for monitoring minimal residual disease in childhood B-precursor ALL. Leukemia, 9, 216-222.
31. Uckun, F.M., Kersey, J.H., Haake, R., Weisdorf, D., Nesbit, M.E. & Ramsay, N.K. (1993) Pretransplantation burden of leukemic progenitor cells as a predictor of relapse after bone marrow transplantation for acute lymphoblastic leukemia. New England Journal of Medicine, 329, 1296-1301.
32. Uckun, F.M., Kersey, J.H., Haake, R., Weisdorf, D. & Ramsay, N.K. (1992) Autologous bone marrow transplantation in high-risk remission B-lineage acute lymphoblastic leukemia using a cocktail of three monoclonal antibodies (BA-1/CD24, BA-2/ CD9, and BA-3/CD10) plus complement and 4-hydroperoxy-cyclophosphamide for ex vivo bone marrow purging. Blood, 79. 1094-1104.
33. van den Berg, H., Vet, R., den Ouden, E. & Behrendt, H. (1995) Significance of lymphoblasts in cerebrospinal fluid in newly diagnosed pediatric acute lymphoblastic malignancies with bone marrow involvement: possible benefit of dexamethasone. Medical and Pediatric Oncology, 25, 22-28.
34. Van der Does-Van den Berg, A., van Wering, E.R., Suciu, S., Solbu, G., van't Veer, M.B., Rammeloo, J.A., De Koning, J. & van Zanen, G.E. (1989) Effectiveness of rubidomycin in induction therapy with vincristine, prednisone, and L-asparaginase for standard risk childhood acute lymphocytic leukemia: results of a Dutch Phase III study (ALL V). American Journal of Pediatric Hematology/Oncology, 11, 125-133.
35. Veerman, A.J.P., Mahlen, K., Kamps, W.A., van Leeuwen, E.F., de Vaan, G.A.M., van Wering, E.R., Van der Does-Van den Berg, A., Solbu, G. & Suciu, S. (1990) Dutch Childhood Leukemia Study Group: early results of Study ALLV1(1984-1988). Haematology and Blood Transfusion. Vol. 33 (eds Buchner et al), p. 473. Springer, Berlin.