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Volumn 125, Issue 8, 1998, Pages 1407-1420

The Drosophila Medea gene is required downstream of dpp and encodes a functional homolog of human Smad4

Author keywords

Dorsal ventral patterning; dpp; Drosophila; Mad; Medea; Smad4; TGF signal transduction

Indexed keywords

MESSENGER RNA; MORPHOGEN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031839403     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (105)

References (74)
  • 1
    • 0028132086 scopus 로고
    • Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis
    • Affolter, M., Nellen, D., Nussbaumer, U. and Basler, K. (1994). Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis. Development 120, 3105-3117.
    • (1994) Development , vol.120 , pp. 3105-3117
    • Affolter, M.1    Nellen, D.2    Nussbaumer, U.3    Basler, K.4
  • 2
    • 0029072998 scopus 로고
    • The Drosophila schnurri gene acts in the Dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human MBP family
    • Arora, K., Dai, H., Kazuko, S. G., Jamal, J., O'Connor, M. B., Letsou, A. and Warrior, R. (1995). The Drosophila schnurri gene acts in the Dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human MBP family. Cell 81, 781-790.
    • (1995) Cell , vol.81 , pp. 781-790
    • Arora, K.1    Dai, H.2    Kazuko, S.G.3    Jamal, J.4    O'Connor, M.B.5    Letsou, A.6    Warrior, R.7
  • 3
    • 0026506514 scopus 로고
    • Altered mitotic domains reveal fate map changes in Drosophila embryos mutant for zygotic dorsoventral patterning genes
    • Arora, K. and Nüsslein-Volhard, C. (1992). Altered mitotic domains reveal fate map changes in Drosophila embryos mutant for zygotic dorsoventral patterning genes. Development 114, 1003-1024.
    • (1992) Development , vol.114 , pp. 1003-1024
    • Arora, K.1    Nüsslein-Volhard, C.2
  • 4
    • 0003455528 scopus 로고
    • Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press
    • Ashburner, M. (1989). Drosophila: A Laboratory- Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
    • (1989) Drosophila: A Laboratory- Manual
    • Ashburner, M.1
  • 5
    • 0029829230 scopus 로고    scopus 로고
    • A novel mesoderm inducer, Madr2 functions in the activin signal transduction pathway
    • Baker, J. and Harland, R. (1996). A novel mesoderm inducer, Madr2 functions in the activin signal transduction pathway. Genes Dev. 10, 1880-1889.
    • (1996) Genes Dev. , vol.10 , pp. 1880-1889
    • Baker, J.1    Harland, R.2
  • 6
    • 0023772113 scopus 로고
    • Functional cDNA libraries from Drosophila embryos
    • Brown, N. H. and Kafatos, F. C. (1988). Functional cDNA libraries from Drosophila embryos. J. Mol. Biol. 203, 425-437.
    • (1988) J. Mol. Biol. , vol.203 , pp. 425-437
    • Brown, N.H.1    Kafatos, F.C.2
  • 8
    • 0025879069 scopus 로고
    • Eukaryotic start and stop translation sites
    • Cavener, D. and Ray, S. (1991). Eukaryotic start and stop translation sites. Nucl. Acids Res. 19, 3185-3192.
    • (1991) Nucl. Acids Res. , vol.19 , pp. 3185-3192
    • Cavener, D.1    Ray, S.2
  • 9
    • 0029802485 scopus 로고    scopus 로고
    • A transcriptional partner for MAD proteins in TGF-beta signalling
    • Chen, X., Rubock, M. and Whitman, M. (1996). A transcriptional partner for MAD proteins in TGF-beta signalling. Nature 383, 691-696.
    • (1996) Nature , vol.383 , pp. 691-696
    • Chen, X.1    Rubock, M.2    Whitman, M.3
  • 11
    • 0029806078 scopus 로고    scopus 로고
    • Regulation of transforming growth factor beta- and activin-induced transcription by mammalian Mad proteins
    • Chen, Y., Lebrun, J. and Vale, W. (1996). Regulation of transforming growth factor beta- and activin-induced transcription by mammalian Mad proteins. Pro. Natl. Acad. Sci. USA 93, 12992-12997.
    • (1996) Pro. Natl. Acad. Sci. USA , vol.93 , pp. 12992-12997
    • Chen, Y.1    Lebrun, J.2    Vale, W.3
  • 12
    • 0030300085 scopus 로고    scopus 로고
    • The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster
    • Chou, T. B. and Perrimon, N. (1996). The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144, 1673-1679.
    • (1996) Genetics , vol.144 , pp. 1673-1679
    • Chou, T.B.1    Perrimon, N.2
  • 13
    • 0026717301 scopus 로고
    • Bone morphogenetic protein 4: A ventralizing factor in early Xenopus development
    • Dale, L., Howes, G., Price, B. M. and Smith, J. C. (1992). Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development. Development 115, 573-585.
    • (1992) Development , vol.115 , pp. 573-585
    • Dale, L.1    Howes, G.2    Price, B.M.3    Smith, J.C.4
  • 14
    • 0023820541 scopus 로고
    • Molecular consequences of awdb3, a cell-autonomous lethal mutation of Drosophila induced by hybrid dysgenesis
    • Dearolf, C. R., Tripoulas, N., Biggs, J. and Shearn, A. (1988). Molecular consequences of awdb3, a cell-autonomous lethal mutation of Drosophila induced by hybrid dysgenesis. Dev. Biol. 129, 169-178.
    • (1988) Dev. Biol. , vol.129 , pp. 169-178
    • Dearolf, C.R.1    Tripoulas, N.2    Biggs, J.3    Shearn, A.4
  • 15
    • 0030789367 scopus 로고    scopus 로고
    • Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus
    • Dosch, R., Gawantka, V., Delius, H., Blumenstock, C. and Niehrs, C. (1997). Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus. Development 124, 2325-2334.
    • (1997) Development , vol.124 , pp. 2325-2334
    • Dosch, R.1    Gawantka, V.2    Delius, H.3    Blumenstock, C.4    Niehrs, C.5
  • 17
    • 0026451642 scopus 로고
    • Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo
    • Ferguson, E. L. and Anderson, K. V. (1992a). Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. Cell 71, 451-461.
    • (1992) Cell , vol.71 , pp. 451-461
    • Ferguson, E.L.1    Anderson, K.V.2
  • 18
    • 0026598187 scopus 로고
    • Localized enhancement and repression of the activity of the TGF-beta family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo
    • Ferguson, E. L. and Anderson, K. V. (1992b). Localized enhancement and repression of the activity of the TGF-beta family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo. Development 114, 583-597.
    • (1992) Development , vol.114 , pp. 583-597
    • Ferguson, E.L.1    Anderson, K.V.2
  • 19
    • 0030754904 scopus 로고    scopus 로고
    • FlyBase - A Drosophila Database
    • FlyBase (1997). FlyBase - A Drosophila Database. Nucl. Acids Res.. 25, 63-66. (http:flybase.bio.indiana.edu)
    • (1997) Nucl. Acids Res.. , vol.25 , pp. 63-66
    • FlyBase1
  • 20
    • 0029940972 scopus 로고    scopus 로고
    • Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily
    • Graff, J., Bansal, A. and Melton, D. (1996). Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily. Cell 85, 479-487.
    • (1996) Cell , vol.85 , pp. 479-487
    • Graff, J.1    Bansal, A.2    Melton, D.3
  • 21
    • 0028990126 scopus 로고
    • Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1
    • Grieder, N. C., Nellen, D., Burke, R., Basler, K. and Affolter, M. (1995). Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1. Cell 81, 791-800.
    • (1995) Cell , vol.81 , pp. 791-800
    • Grieder, N.C.1    Nellen, D.2    Burke, R.3    Basler, K.4    Affolter, M.5
  • 23
    • 0029802904 scopus 로고    scopus 로고
    • Genetic analysis of dorsoventral pattern formation in the zebrafish: Requirement of a BMP-like ventralizing activity and its dorsal repressor
    • Hammerschmidt, M., Serbedzija, G. N. and McMahon, A. P. (1996). Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor. Genes Dev. 10, 2452-2461.
    • (1996) Genes Dev. , vol.10 , pp. 2452-2461
    • Hammerschmidt, M.1    Serbedzija, G.N.2    McMahon, A.P.3
  • 25
    • 0031438047 scopus 로고    scopus 로고
    • TGF-beta signalling from cell membrane to nucleus through SMAD proteins
    • Heldin, C. H., Miyazono, K. and ten Dijke, P. (1997). TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 390, 465-471.
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Ten Dijke, P.3
  • 26
    • 0030598871 scopus 로고    scopus 로고
    • The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor
    • Holley, S. A., Neul, J. L., Attisano, L., Wrana, J. L., Sasai, Y., O'Connor, M. B., De Robertis, E. M. and Ferguson, E. L. (1996). The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor. Cell 86, 607-617.
    • (1996) Cell , vol.86 , pp. 607-617
    • Holley, S.A.1    Neul, J.L.2    Attisano, L.3    Wrana, J.L.4    Sasai, Y.5    O'Connor, M.B.6    De Robertis, E.M.7    Ferguson, E.L.8
  • 29
    • 0023424002 scopus 로고
    • The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo
    • Irish, V. F. and Gelbart, W. M. (1987). The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo. Genes Dev. 1, 868-879.
    • (1987) Genes Dev. , vol.1 , pp. 868-879
    • Irish, V.F.1    Gelbart, W.M.2
  • 30
    • 0026680530 scopus 로고
    • DVR-4 (bone morphogenetic protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction
    • Jones, C. M., Lyons, K. M., Lapan, P. M., Wright, C. V. and Hogan, B. L. (1992). DVR-4 (bone morphogenetic protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction. Development 115, 639-647.
    • (1992) Development , vol.115 , pp. 639-647
    • Jones, C.M.1    Lyons, K.M.2    Lapan, P.M.3    Wright, C.V.4    Hogan, B.L.5
  • 31
    • 0030872367 scopus 로고    scopus 로고
    • Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
    • Kim, J., Johnson, K., Chen, H., Carroll, S. and Laughon, A. (1997). Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature 388, 304-308.
    • (1997) Nature , vol.388 , pp. 304-308
    • Kim, J.1    Johnson, K.2    Chen, H.3    Carroll, S.4    Laughon, A.5
  • 32
    • 0029834067 scopus 로고    scopus 로고
    • Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways
    • Lagna, G., Hata, A., Hemmati-Brivanlou, A. and Massague, J. (1996). Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Nature 383, 832-836.
    • (1996) Nature , vol.383 , pp. 832-836
    • Lagna, G.1    Hata, A.2    Hemmati-Brivanlou, A.3    Massague, J.4
  • 34
    • 0029931509 scopus 로고    scopus 로고
    • A human Mad protein acting as a BMP-regulated transcriptional activator
    • Liu, F., Hata, A., Baker, J., Doody, J., Carcamo, J., Harland, R. and Massague, J. (1996). A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381, 620-623.
    • (1996) Nature , vol.381 , pp. 620-623
    • Liu, F.1    Hata, A.2    Baker, J.3    Doody, J.4    Carcamo, J.5    Harland, R.6    Massague, J.7
  • 35
    • 0030886204 scopus 로고    scopus 로고
    • Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells
    • Liu, X., Sun, Y., Constantinescu, S., Karam, E., Weinberg, R. and Lodish, H. (1997). Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc. Natl. Acad. Sci. USA 94, 10669-10674.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10669-10674
    • Liu, X.1    Sun, Y.2    Constantinescu, S.3    Karam, E.4    Weinberg, R.5    Lodish, H.6
  • 36
    • 0023815070 scopus 로고
    • Dosage-dependent modifiers of position effect variegation in Drosophila and a mass action model that explains their effect
    • Locke, J., Kotarski, M. A. and Tartof, K. D. (1988). Dosage-dependent modifiers of position effect variegation in Drosophila and a mass action model that explains their effect. Genetics 120, 181-198.
    • (1988) Genetics , vol.120 , pp. 181-198
    • Locke, J.1    Kotarski, M.A.2    Tartof, K.D.3
  • 37
    • 0030300115 scopus 로고    scopus 로고
    • MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
    • Macias-Silva, M., Abdollah, S., Hoodless, P., Pirone, R., Attisano, L. and Wrana, J. (1996). MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling. Cell 87, 1215-1224.
    • (1996) Cell , vol.87 , pp. 1215-1224
    • Macias-Silva, M.1    Abdollah, S.2    Hoodless, P.3    Pirone, R.4    Attisano, L.5    Wrana, J.6
  • 38
    • 0030604542 scopus 로고    scopus 로고
    • TGF-beta signaling: Receptors, transducers, and Mad proteins
    • Massagué, J. (1996). TGF-beta signaling: receptors, transducers, and Mad proteins. Cell 85, 947-950.
    • (1996) Cell , vol.85 , pp. 947-950
    • Massagué, J.1
  • 41
    • 0027953772 scopus 로고
    • Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic
    • Nellen, D., Affolter, M. and Basler, K. (1994). Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic. Cell 78, 225-237.
    • (1994) Cell , vol.78 , pp. 225-237
    • Nellen, D.1    Affolter, M.2    Basler, K.3
  • 42
    • 0030018425 scopus 로고    scopus 로고
    • Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-beta responsive cells
    • Newfeld, S., Chartoff, E., Graff, J., Melton, D. and Gelbart, W. (1996). Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-beta responsive cells. Development 122, 2099-2108.
    • (1996) Development , vol.122 , pp. 2099-2108
    • Newfeld, S.1    Chartoff, E.2    Graff, J.3    Melton, D.4    Gelbart, W.5
  • 43
    • 0030885190 scopus 로고    scopus 로고
    • Mothers against dpp participates in a DPP/TGF-beta responsive serine-threonine kinase signal transduction cascade
    • Newfeld, S., Mehra, A., Singer, M., Wrana, J., Attisano, L. and Gelbart, W. (1997). Mothers against dpp participates in a DPP/TGF-beta responsive serine-threonine kinase signal transduction cascade. Development 124, 3167-3176.
    • (1997) Development , vol.124 , pp. 3167-3176
    • Newfeld, S.1    Mehra, A.2    Singer, M.3    Wrana, J.4    Attisano, L.5    Gelbart, W.6
  • 44
    • 0028141433 scopus 로고
    • Identification of two bone morphogenetic protein type I receptors in Drosophila evidence that Brk25D is a decapentaplegic receptor
    • Penton, A., Chen, Y., Staehling-Hampton, K., Wrana, J. L., Attisano, L., Szidonya, J., Cassill, J. A., Massague, J. and Hoffmann, F. M. (1994). Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor. Cell 78, 239-250.
    • (1994) Cell , vol.78 , pp. 239-250
    • Penton, A.1    Chen, Y.2    Staehling-Hampton, K.3    Wrana, J.L.4    Attisano, L.5    Szidonya, J.6    Cassill, J.A.7    Massague, J.8    Hoffmann, F.M.9
  • 45
    • 0028893294 scopus 로고
    • Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila
    • Raftery, L. A., Twombly, V., Wharton, K. and Gelbart, W. M. (1995). Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila. Genetics 139, 241-254.
    • (1995) Genetics , vol.139 , pp. 241-254
    • Raftery, L.A.1    Twombly, V.2    Wharton, K.3    Gelbart, W.M.4
  • 46
    • 0028923022 scopus 로고
    • An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo
    • Ruberte, E., Marty, T., Nellen, D., Affolter, M. and Basler, K. (1995). An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo. Cell 80, 889-897.
    • (1995) Cell , vol.80 , pp. 889-897
    • Ruberte, E.1    Marty, T.2    Nellen, D.3    Affolter, M.4    Basler, K.5
  • 47
    • 0023650412 scopus 로고
    • Maternal regulation of zerknullt: A homoeobox gene controlling differentiation of dorsal tissues in Drosophila
    • Rushlow, C., Frasch, M., Doyle, H. and Levine, M. (1987). Maternal regulation of zerknullt: a homoeobox gene controlling differentiation of dorsal tissues in Drosophila. Nature 330, 583-586.
    • (1987) Nature , vol.330 , pp. 583-586
    • Rushlow, C.1    Frasch, M.2    Doyle, H.3    Levine, M.4
  • 48
    • 0025028635 scopus 로고
    • Role of the zerknüllt gene in dorsal-ventral pattern formation in Drosophila
    • Rushlow, C. and Levine, M. (1990). Role of the zerknüllt gene in dorsal-ventral pattern formation in Drosophila. Adv. Genet. 27, 277-307.
    • (1990) Adv. Genet. , vol.27 , pp. 277-307
    • Rushlow, C.1    Levine, M.2
  • 50
    • 0030058914 scopus 로고    scopus 로고
    • Caenorhabditis elegans genes sma-2, sma-3, and sma4 define a conserved family of transforming growth factor beta pathway components
    • Savage, C., Das, P., Finelli, A., Townsend, S., Sun, C., Baird, S. and Padgett, R. (1996). Caenorhabditis elegans genes sma-2, sma-3, and sma4 define a conserved family of transforming growth factor beta pathway components. Proc. Natl. Acad. Sci. USA 93, 790-794.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 790-794
    • Savage, C.1    Das, P.2    Finelli, A.3    Townsend, S.4    Sun, C.5    Baird, S.6    Padgett, R.7
  • 51
    • 0027076843 scopus 로고
    • Formation of the Drosophila larval photoreceptor organ and its neuronal differentiation require continuous Krüppel gene activity
    • Schmucker, D., Taubert, H. and Jackle, H. (1992). Formation of the Drosophila larval photoreceptor organ and its neuronal differentiation require continuous Krüppel gene activity. Neuron 9, 1025-1039.
    • (1992) Neuron , vol.9 , pp. 1025-1039
    • Schmucker, D.1    Taubert, H.2    Jackle, H.3
  • 53
    • 0028940853 scopus 로고
    • Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster
    • Sekelsky, J. J., Newfeld, S. J., Raftery, L. A., Chartoff, E. H. and Gelbart, W. M. (1995). Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139, 1347-1358.
    • (1995) Genetics , vol.139 , pp. 1347-1358
    • Sekelsky, J.J.1    Newfeld, S.J.2    Raftery, L.A.3    Chartoff, E.H.4    Gelbart, W.M.5
  • 54
    • 0030837455 scopus 로고    scopus 로고
    • A structural basis for mutational inactivation of the tumour suppressor Smad4
    • Shi, Y., Hata, A., Lo, R., Massague, J. and Pavletich, N. (1997). A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature 388, 87-93.
    • (1997) Nature , vol.388 , pp. 87-93
    • Shi, Y.1    Hata, A.2    Lo, R.3    Massague, J.4    Pavletich, N.5
  • 55
    • 0020075326 scopus 로고
    • Decapentaplegic: A gene complex affecting morphogenesis in Drosophila melanogaster
    • Spencer, F. A., Hoffmann, F. M. and Gelbart, W. M. (1982). Decapentaplegic: a gene complex affecting morphogenesis in Drosophila melanogaster. Cell 28, 451-461.
    • (1982) Cell , vol.28 , pp. 451-461
    • Spencer, F.A.1    Hoffmann, F.M.2    Gelbart, W.M.3
  • 56
    • 0023408868 scopus 로고
    • Decapentaplegic transcripts are localized along the dorsal-ventral axis of the Drosophila embryo
    • St. Johnston, R. D. and Gelbart, W. M. (1987). Decapentaplegic transcripts are localized along the dorsal-ventral axis of the Drosophila embryo. EMBO J 6, 2785-2791.
    • (1987) EMBO J , vol.6 , pp. 2785-2791
    • St Johnston, R.D.1    Gelbart, W.M.2
  • 58
    • 0026580006 scopus 로고
    • Brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2
    • Tamkun, J. W., Deuring, R., Scott, M. P., Kissinger, M., Pattatucci, A. M., Kaufman, T. C. and Kennison, J. A. (1992). brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 68, 561-572.
    • (1992) Cell , vol.68 , pp. 561-572
    • Tamkun, J.W.1    Deuring, R.2    Scott, M.P.3    Kissinger, M.4    Pattatucci, A.M.5    Kaufman, T.C.6    Kennison, J.A.7
  • 59
    • 0028108028 scopus 로고
    • The thick veins gene of Drosophila is required for dorsoventral polarity of the embryo
    • Terracol, R. and Lengyel, J. A. (1994). The thick veins gene of Drosophila is required for dorsoventral polarity of the embryo. Genetics 138, 165-178.
    • (1994) Genetics , vol.138 , pp. 165-178
    • Terracol, R.1    Lengyel, J.A.2
  • 61
    • 0029834231 scopus 로고    scopus 로고
    • Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor
    • Thomsen, G. (1996). Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor. Development 122, 2359-2366.
    • (1996) Development , vol.122 , pp. 2359-2366
    • Thomsen, G.1
  • 62
    • 0030863365 scopus 로고    scopus 로고
    • Daughters against dpp modulates dpp organizing activity in Drosophila wing development
    • Tsuneizumi, K., Nakayama, T., Kamoshida, Y., Kornberg, T., Christian, J. and Tabata, T. (1997). Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature 389, 627-631.
    • (1997) Nature , vol.389 , pp. 627-631
    • Tsuneizumi, K.1    Nakayama, T.2    Kamoshida, Y.3    Kornberg, T.4    Christian, J.5    Tabata, T.6
  • 64
    • 0021326563 scopus 로고
    • Defects in embryogenesis in mutants associated with the antennapedia gene complex of Drosophila melanogaster
    • Wakimoto, B. T., Turner, F. R. and Kaufman, T. C. (1984). Defects in embryogenesis in mutants associated with the antennapedia gene complex of Drosophila melanogaster. Dev. Biol. 102, 147-172.
    • (1984) Dev. Biol. , vol.102 , pp. 147-172
    • Wakimoto, B.T.1    Turner, F.R.2    Kaufman, T.C.3
  • 65
    • 0027467829 scopus 로고
    • An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo
    • Wharton, K. A., Ray, R. P. and Gelbart, W. M. (1993). An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo. Development 117, 807-822.
    • (1993) Development , vol.117 , pp. 807-822
    • Wharton, K.A.1    Ray, R.P.2    Gelbart, W.M.3
  • 67
    • 0030886059 scopus 로고    scopus 로고
    • Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1
    • Wilson, P. A., Lagna, G., Suzuki, A. and Hemmati-Brivanlou, A. (1997). Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1. Development 124, 3177-3184.
    • (1997) Development , vol.124 , pp. 3177-3184
    • Wilson, P.A.1    Lagna, G.2    Suzuki, A.3    Hemmati-Brivanlou, A.4
  • 70
    • 0028218186 scopus 로고
    • The Drosophila saxophone gene: A serine-threonine kinase receptor of the TGF-beta superfamily
    • Xie, T., Finelli, A. L. and Padgett, R. W. (1994). The Drosophila saxophone gene: a serine-threonine kinase receptor of the TGF-beta superfamily. Science 263, 1756-1759
    • (1994) Science , vol.263 , pp. 1756-1759
    • Xie, T.1    Finelli, A.L.2    Padgett, R.W.3
  • 71
    • 0027159969 scopus 로고
    • Tramtrack is a transcriptional represser required for cell fate determination in the Drosophila eye
    • Xiong, W. C. and Montell, C. (1993). tramtrack is a transcriptional represser required for cell fate determination in the Drosophila eye. Genes Dev. 7, 1085-1096.
    • (1993) Genes Dev. , vol.7 , pp. 1085-1096
    • Xiong, W.C.1    Montell, C.2
  • 72
    • 0030697971 scopus 로고    scopus 로고
    • Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein
    • Yingling, J. M., Datto, M. B., Wong, C., Frederick, J. P., Liberati, N. T. and Wang, X. F. (1997). Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein. Mol. Cell. Biol. 17, 7019-7028.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 7019-7028
    • Yingling, J.M.1    Datto, M.B.2    Wong, C.3    Frederick, J.P.4    Liberati, N.T.5    Wang, X.F.6
  • 73
    • 0029786212 scopus 로고    scopus 로고
    • Receptor-associated Mad homologues synergize as effectors of the TGF-beta response
    • Zhang, Y., Feng, X., We, R. and Derynck, R. (1996). Receptor-associated Mad homologues synergize as effectors of the TGF-beta response. Nature 383, 168-172.
    • (1996) Nature , vol.383 , pp. 168-172
    • Zhang, Y.1    Feng, X.2    We, R.3    Derynck, R.4
  • 74
    • 0031128153 scopus 로고    scopus 로고
    • The tumor suppressor Smad4/DPC 4 as a central mediator of S mad function
    • Zhang, Y., Musci, T. and Derynck, R. (1997). The tumor suppressor Smad4/DPC 4 as a central mediator of S mad function. Current Biol. 7, 270-276.
    • (1997) Current Biol. , vol.7 , pp. 270-276
    • Zhang, Y.1    Musci, T.2    Derynck, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.