Poxviruses: Capturing cytokines and chemokines

Seminars in Virology

Volumn 8, Issue 5, 1998, Pages 419-427

  Alcamí, Antonio ^a   Symons, Julian A ^a   Khanna, Anu ^a   Smith, Geoffrey L ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Chemokine; Cytokine; Poxvirus; Receptor; Virus pathogenesis

Indexed keywords

BINDING PROTEIN; CHEMOKINE; CHEMOKINE RECEPTOR; CYTOKINE; CYTOKINE RECEPTOR; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; DNA VIRUS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; NONHUMAN; POXVIRUS; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN STRUCTURE; REVIEW; VIRUS INFECTION; VIRUS PATHOGENESIS;

ANIMALIA; DNA VIRUSES; POXVIRIDAE;

EID: 0031831342     PISSN: 10445773     EISSN: None     Source Type: Journal    
DOI: 10.1006/smvy.1997.0143     Document Type: Article

References (74)

1. Alcamí A., Smith G. L. Cytokine receptors encoded by poxviruses: A lesson in cytokine biology. Immunol. Today. 16:1995;474-478.
2. McFadden G., Graham K., Ellison K., Barry M., Macen J., Schreiber M., Mossman K., Nash P., Lalani A., Everett H. Interruption of cytokine networks by poxviruses: Lessons from myxoma virus. J. Leukocyte Biol. 57:1995;731-738.
3. Smith G. L. Virus proteins that bind cytokines, chemokines or interferons. Curr. Opin. Immunol. 8:1996;467-471.
4. Spriggs M. K. One step ahead of the game: Viral immunomodulatory molecules. Annu. Rev. Immunol. 14:1996;101-130.
5. Moore P. S., Boshoff C., Weiss R. A., Chang Y. Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV. Science. 274:1996;1739-1744.
6. Murphy P. M. Chemokine receptors: structure, function and role in microbial pathogenesis. Cytokine Growth Factor Rev. 7:1996;47-64.
7. Senkevich T. G., Bugert J. J., Sisler J. R., Koonin E. V., Darai G., Moss B. Genome sequence of a human tumorigenic poxvirus: prediction of specific host response-evasion genes. Science. 273:1996;813-816.
8. Fleming S. B., McCaughan C. A., Andrews A. E., Nash A. D., Mercer A. A. A homolog of interleukin-10 is encoded by the poxvirus orf virus. J. Virol. 71:1997;4857-4861.
9. Smith G. L., Symons J. A., Alcamí A. Poxviruses: Interfering with interferon. Semin. Virol. 8:1998;409-418.
10. Essani K., Chalasani S., Eversole R., Beuving L., Birmingham L. Multiple anti-cytokine activities secreted from tanapox virus-infected cells. Microb. Pathog. 17:1994;347-353.
11. Beutler B. Tumor Necrosis Factors: The Molecules and Their Emerging Role in Medicine. 1992;Raven Press, New York.
12. Crowe P. D., VanArsdale T. L., Walter B. N., Ware C. F., Hession C., Ehrenfels B., Browning J. L., Din W. S., Goodwin R. G., Smith C. A. A lymphotoxin-β-specific receptor. Science. 264:1994;707-710.
13. Browning J. L., Ngam-ek A., Lawton P., De Marinis J., Tizard R., Chow E. P., Hession C., O'Brine-Greco B., Foley S. F., Ware C. F. Lymphotoxin β, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface. Cell. 72:1993;847-856.
14. Smith C. A., Davis T., Wignall J. M., Din W. S., Farrah T., Upton C., McFadden G., Goodwin R. G. T2 open reading frame from Shope fibroma virus encodes a soluble form of the TNF receptor. Biochem. Biophys. Res. Commun. 176:1991;335-342.
15. Upton C., Macen J. L., Schreiber M., McFadden G. Myxoma virus expresses a secreted protein with homology to the tumor necrosis factor receptor gene family that contributes to viral virulence. Virology. 184:1991;370-382.
16. Howard S. T., Chan Y. S., Smith G. L. Vaccinia virus homologues of the Shope fibroma virus inverted terminal repeat proteins and a discontinuous ORF related to the tumour necrosis factor receptor family. Virology. 180:1991;633-647.
17. Schreiber M., McFadden G. The myxoma virus TNF-receptor homologue (T2) inhibits tumor necrosis factor-alpha in a species-specific fashion. Virology. 204:1994;692-705.
18. Goebel S. J., Johnson G. P., Perkus M. E., Davis S. W., Winslow J. P., Paoletti E. The complete DNA sequence of vaccinia virus. Virology. 179:1990;247-266.
19. Hu F., Smith C. A., Pickup D. J. Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor. Virology. 204:1994;343-356.
20. Smith C. A., Hu F. Q., Smith T. D., Richards C. L., Smolak P., Goodwin R. G., Pickup D. J. Cowpox virus genome encodes a second soluble homologue of cellular TNF receptors, distinct from CrmB, that binds TNF but not LT alpha. Virology. 223:1996;132-147.
21. Aguado B., Selmes I. P., Smith G. L. Nucleotide sequence of 21.8 kbp of variola major virus strain Harvey and comparison with vaccinia virus. J. Gen. Virol. 73:1992;2887-2902.
22. Alcamí A., Smith G. L. Comment on the paper by Shchelkunovet al.(1993)FEBS Letters319, 80-83: Two genes encoding poxvirus cytokine receptors are disrupted or deleted in variola virus. FEBS Lett. 335:1993;136-137.
23. Shchelkunov S. N., Blinov V. M., Sandakhchiev L. S. Genes of variola and vaccinia viruses necessary to overcome the host protective mechanisms. FEBS Lett. 319:1993;80-83.
24. Massung R. F., Liu L., Qi J., Knight J. C., Yuran T. E., Kerlavage A. R., Parsons J. M., Venter J. C., Esposito J. J. Analysis of the complete genome of smallpox variola major virus strain Bangladesh-1975. Virology. 201:1994;215-240.
25. Tidona C. A., Darai G. The complete DNA sequence of lymphocystis disease virus. Virology. 230:1997;207-216.
26. Beck G., Habicht G. S. Primitive cytokines: Harbingers of vertebrate defense. Immunol. Today. 12:1991;180-183.
27. McFadden G., Barry M. How poxviruses oppose apoptosis. Semin. Virol. 8:1998;429-442.
28. Schreiber M., Rajarathnam K., McFadden G. Myxoma virus T2 protein, a tumor necrosis factor (TNF) receptor homolog, is secreted as a monomer and dimer that each bind rabbit TNFα, but the dimer is a more potent TNF inhibitor. J. Biol. Chem. 271:1996;13333-13341.
29. Schreiber M., McFadden G. Mutational analysis of the ligand-binding domain of M-T2 protein, the tumor necrosis factor receptor homologue of myxoma virus. J. Immunol. 157:1996;4486-4495.
30. Schreiber M., Sedger L., McFadden G. Distinct domains of M-T2, the myxoma virus tumor necrosis factor (TNF) receptor homolog, mediate extracellular TNF binding and intracellular apoptosis inhibition. J. Virol. 71:1997;2171-2181.
31. Dinarello C. A. Biological basis for interleukin-1 in disease. Blood. 87:1996;2095-2147.
32. Smith G. L., Chan Y. S. Two vaccinia virus proteins structurally related to interleukin-1 receptor and the immunoglobulin superfamily. J. Gen. Virol. 72:1991;511-518.
33. McMahan C. J., Slack J. L., Mosley B., Cosman D., Lupton S. D., Brunton L. L., Grubin C. E., Wignall J. M., Jenkins N. A., Branan C. I., Copeland N. G., Huebner K., Croce C. M., Cannizzarro L. A., Benjamin D., Dower S. K., Spriggs M. K., Sims J. E. A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. EMBO J. 10:1991;2821-2832.
34. Alcamí A., Smith G. L. A soluble receptor for interleukin-1β encoded by vaccinia virus: a novel mechanism of virus modulation of the host response to infection. Cell. 71:1992;153-167.
35. Spriggs M. K., Hruby D. E., Maliszewski C. R., Pickup D. J., Sims J. E., Buller R. M., VanSlyke J. Vaccinia and cowpox viruses encode a novel secreted interleukin-1-binding protein. Cell. 71:1992;145-152.
36. Alcamí A., Smith G. L. A mechanism for the inhibition of fever by a virus. Proc. Natl. Acad. Sci. USA. 93:1996;11029-11034.
37. Kluger M. J. Fever: Role of pyrogens and cryogens. Physiol. Rev. 71:1991;93-125.
38. Zheng H., Fletcher D., Kozak W., Jiang M., Hofmann K. J., Conn C. A., Soszynski D., Grabiec C., Trumbauer M. E., Shaw A., Kostura M. J., Stevens K., Rosen H., North R. J., Chen H. Y., Tocci M. J., Kluger M. J., Van der Ploeg L. H. T. Resistance to fever induction and impaired acute-phase response in interleukin-1β-deficient mice. Immunity. 3:1995;9-19.
39. Kozak W., Zheng H., Conn C. A., Soszynski D., van der Ploeg L. H., Kluger M. J. Thermal and behavioral effects of lipopolysaccharide and influenza in interleukin-1 beta-deficient mice. Am. J. Physiol. 269:1995;R969-977.
40. Alcamí A., Smith G. L. Interleukin-1 receptors encoded by poxviruses. Viroceptors, Virokines and Related Immune Modulators Encoded by DNA Viruses. 1995;R. G. Landes, Austin. p. 17-27.
41. Ray C. A., Black R. A., Kronheim S. R., Greenstreet T. A., Sleath P. R., Salvensen G. S., Pickup D. J. Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme. Cell. 69:1992;597-604.
42. Kettle S., Alcamí A., Khanna A., Ehret R., Jassoy C., Smith G. L. Vaccinia virus serpin B13R (SPI-2) inhibits interleukin-1β-converting enzyme and protects virus-infected cells from TNF- and Fas-mediated apoptosis, but does not prevent IL-1β-induced fever. J. Gen. Virol. 78:1997;677-685.
43. Petit F., Bertagnoli S., Gelfi J., Fassy F., Boucraut-Baralon C., Milon A. Characterization of a myxoma virus-encoded serpin-like protein with activity against interleukin-1β-converting enzyme. J. Virol. 70:1996;5860-5866.
44. Ghayur T., Banerjee S., Hugunin M., Butler D., Herzog L., Carter A., Quintal L., Sekut L., Talanian R., Paskind M., Wong W., Kamen R., Tracey D., Allen H. Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN-γ production. Nature. 386:1997;619-623.
45. Dobbelstein M., Shenk T. Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product. J. Virol. 70:1996;6479-6485.
46. Ray C. A., Pickup D. J. The mode of death of pig kidney cells infected with cowpox virus is governed by the expression of the crmA gene. Virology. 217:1996;384-391.
47. D'Souza M. P., Harden V. A. Chemokines and HIV-1 second receptors. Nature Med. 2:1996;1293-1300.
48. Fauci A. S. Host factors and the pathogenesis of HIV-induced disease. Nature. 384:1996;529-534.
49. Howard O. M. Z., Ben-Baruch A., Oppenheim J. J. Chemokines: Progress toward identifying molecular targets for therapeutic agents. Trends Biotechnol. 14:1996;46-51.
50. Premack B. A., Schall T. J. Chemokine receptors: Gateways to inflammation and infection. Nature Med. 2:1996;1174-1178.
51. Rollins B. J. Chemokines. Blood. 90:1997;909-928.
52. Schall T. J., Bacon K. B. Chemokines, leukocyte trafficking, and inflammation. Curr. Opin. Immunol. 6:1994;865-873.
53. Witt D. P., Lander A. D. Differential binding of chemokines to glycosaminoglycan subpopulations. Curr. Biol. 4:1994;394-400.
54. Webb L. M. C., Ehrengruber M. U., Clark-Lewis I., Baggiolini M., Rot A. Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8. Proc. Natl. Acad. Sci. USA. 90:1993;7158-7162.
55. Graham G. J., Wilkinson P. C., Nibbs R. J. B., Lowe S., Kolset S. O., Parker A., Freshney M. G., Tsang M. L. S., Pragnell I. B. Uncoupling of stem cell inhibition from monocyte chemoattraction in MIP-1α by mutagenesis of the proteoglycan binding site. EMBO J. 15:1996;6506-6515.
56. Massung R. F., Jayarama V., Moyer R. W. DNA sequence analysis of conserved and unique regions of swinepox virus: identification of genetic elements supporting phenotypic observations including a novel G protein-coupled receptor homologue. Virology. 197:1993;511-528.
57. Cao J. X., Gershon P. D., Black D. N. Sequence analysis ofHindIII Q2 fragment of capripoxvirus reveals a putative gene encoding a G-protein-coupled chemokine receptor homologue. Virology. 209:1995;207-212.
58. Lalani A. S., Graham K., Mossman K., Rajarathnam K., Clark-Lewis I., Kelvin D., McFadden G. The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines. J. Virol. 71:1997;4356-4363.
59. Graham K. A., Lalani A. S., Macen J. L., Ness T. L., Barry M., Liu L., Lucas A., Clark-Lewis I., Moyer R. W., McFadden G. The T1/35kDa family of poxvirus-secreted proteins bind chemokines and modulate leukocyte influx into virus-infected tissues. Virology. 229:1997;12-24.
60. Alcamí A., Symons J. A., Collins P. D., Williams T. J., Smith G. L. Blockade of chemokine activity by a soluble chemokine binding protein from vaccinia virus. J. Immunol. 160:1998;624-633.
61. Mossman K., Nation P., Macen J., Garbutt M., Lucas A., McFadden G. Myxoma M-T7, a secreted homolog of the interferon-γ receptor, is a critical virulence factor for the development of myxomatosis in european rabbits. Virology. 215:1996;17-30.
62. Martínez-Pomares L., Thompson J. P., Moyer R. W. Mapping and investigation of the role in pathogenesis of the major unique secreted 35-kDa protein of rabbitpox virus. Virology. 206:1995;591-600.
63. Patel A. H., Gaffney D. F., Subak-Sharpe J. H., Stow N. D. DNA sequence of the gene encoding a major secreted protein of vaccinia virus, strain Lister. J. Gen. Virol. 71:1990;2013-2021.
64. Smith G. L. Expression of genes by vaccinia virus vectors. Davison A. J., Elliot R. Molecular Virology: A Practical Approach. 1993;257-283 Oxford Univ. Press, Oxford.
65. Shchelkunov S. N. Functional organization of variola major and vaccinia virus genomes. Virus Genes. 10:1995;53-71.
66. Mossman K., Upton C., McFadden G. The myxoma virus-soluble interferon-γ receptor homolog, M-T7, inhibits interferon-γ in a species-specific manner. J. Biol. Chem. 270:1995;3031-3038.
67. Jose P. J., Griffiths-Johnson D. A., Collins P. D., Walsh D. T., Moqbel R., Totty N. F., Truong O., Hsuan J. J., Williams T. J. Eotaxin: A potent eosinophil chemoattractant cytokine detected in a guinea-pig model of allergic airways inflammation. J. Exp. Med. 179:1994;881-887.
68. Heaney M. L., Golde D. W. Soluble cytokine receptors. Blood. 87:1996;847-857.
69. Rose-John S., Heinrich P. C. Soluble receptors for cytokines and growth factors: Generation and biological function. Biochem. J. 300:1994;281-290.
70. Upton C., Mossman K., McFadden G. Encoding of a homolog of IFN-γ receptor by myxoma virus. Science. 258:1992;1369-1372.
71. Mossman K., Upton C., Buller R. M., McFadden G. Species specificity of ectromelia virus and vaccinia virus interferon-gamma binding proteins. Virology. 208:1995;762-769.
72. Alcamí A., Smith G. L. Vaccinia, cowpox and camelpox viruses encode soluble interferon-γ receptors with novel broad species specificity. J. Virol. 69:1995;4633-4639.
73. Symons J. A., Alcamí A., Smith G. L. Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species specificity. Cell. 81:1995;551-560.
74. Colamonici O. R., Domanski P., Sweitzer S. M., Larner A., Buller R. M. L. Vaccinia virus B18R gene encodes a type I interferon-binding protein that blocks interferon alpha transmembrane signaling. J. Biol. Chem. 270:1995;15974-15978.