The physiological role of P450-derived arachidonic acid metabolites

Folia Pharmacologica Japonica

Volumn 112, Issue 1, 1998, Pages 23-31

  Imaoka, Susumu ^a   Funae, Yoshihiko ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

20 hydroxyeicosatetraenoic acid; Arachidonic acid; Cytochrome P450; EDHF; Epoxyeicosatrienoic acid

Indexed keywords

ARACHIDONIC ACID; CYTOCHROME P450; HYDROXYICOSATETRAENOIC ACID; NITRIC OXIDE; PROSTAGLANDIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARACHIDONIC ACID METABOLISM; CONTROLLED STUDY; EPOXIDATION; FEEDBACK SYSTEM; GLOMERULUS; HYDROXYLATION; ION TRANSPORT; KIDNEY TUBULE; NONHUMAN; OXIDATION; RAT; SHORT SURVEY; SPONTANEOUSLY HYPERTENSIVE RAT; VASOCONSTRICTION;

EID: 0031818004     PISSN: 00155691     EISSN: None     Source Type: Journal    
DOI: 10.1254/fpj.112.23     Document Type: Short Survey

References (45)

1. Capdevila J, Chacos N, Werringloer J, Prough RA and Estabrook RW: Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid. Proc Natl Acad Sci USA 78, 5362-5366 (1981)
2. Makita K, Falck JR and Capdevila JH: Cytochrome P450, the arachidonic acid cascade, and hypertension: new vistas for an old enzyme system. FASEB J 10, 1456-1463 (1996)
3. Nelson DR, Koymans L, Kamataki T, Stegeman JJ, Feyereisen R, Waxman DJ, Waterman MR, Gotoh O, Coon MJ, Estabrook RW, et al: P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics 6, 1-42 (1996)
4. 4 ω-hydroxylase. J Biol Chem 268, 9376-9380 (1993)
5. Strobel HW, Geng J, Kawashima H and Wang H: Cytochrome P450-dependent biotransformation of drugs and other xenobiotic substrates in neural tissue. Drug Metab Rev 29, 1079-1105 (1997)
6. Capdevila JH, Falck JR and Estabrook RW: Cytochrome P450 and the arachidonate cascade. FASEB J 6, 731-736 (1992)
7. Funae Y and Imaoka S: Purification and characterization of liver microsomal cytochrome P-450 from untreated male rats. Biochim Biophys Acta 926, 349-358 (1987)
8. Imaoka S, Nagashima K and Funae Y: Characterization of three cytochrome P450s purified from renal microsomes of untreated male rats and comparison with human renal cytochrome P450. Arch Biochem Biophys 276, 473-480 (1990)
9. Imaoka S and Funae Y: Purification and characterization of rat pulmonary cytochrome P-450. J Biochem (Tokyo) 108, 33-36 (1990)
10. Funae Y, Imaoka S and Shimojo N: Purification and characterization of diabetes-inducible cytochrome P-450. Biochem Int 16, 503-509 (1988)
11. Imaoka S, Terano Y and Funae Y: Expression of four phenobarbital-inducible cytochrome P-450s in liver, kidney, and lung of rats. J Biochem (Tokyo) 105, 939-945 (1989)
12. +-ATPase in the cornea. Proc Natl Acad Sci USA 84, 8125-8129 (1987)
13. Woollard P: Stereochemical differences between 12-hydroxy-5,8,10,14-eicosatetraenoic acid in platelets and psoriatic lesions. Biochem Biophys Res Commun 136, 169-175 (1986)
14. Imaoka S, Tanaka S and Funae Y: ω- And (ω-1)-hydroxylation of lauric acid and arachidonic acid by rat renal cytochrome P-450. Biochem Int 18, 731-740 (1989)
15. 1 by multiple forms of cytochrome P-450 purified from rat hepatic microsomes. Biochim Biophys Acta 1043, 177-181 (1990)
16. Abraham NG, Pinto A, Mullane KM, Levere RD and Spokas E: Presense of cytochrome P-450-dependent monooxygenase in intimai cells of the hog aorta. Hypertension 7, 899-904 (1985)
17. Proctor KG, Falck JR and Capdevila J: Intestinal vasodilation by epoxyeicosatrienoic acids: arachidonic acid metabolites produced by a cytochrome P 450 monooxygenase. Circ Res 60, 50-59 (1987)
18. Oyekan AO, McGiff JC and Quilley J: Cytochrome P-450-dependent vasodilation of rat kidney by arachidonic acid. Am J Physiol 261, H714-719 (1991)
19. Escalante B, Omata K, Sessa W, Lee SG, Falck JR and Schwartzman ML: 20-Hydroxyeicosatetraenoic acid is an endothelium-dependent vasoconstrictor in rabbit arteries. Eur J Pharmacol 235, 1-7 (1993)
20. Carroll MA, Sala A, Dunn CE, McGiff JC and Murphy RC: Structural identification of cytochrome P450-dependent arachidonate metabolites formed by rabbit medullary thick ascending limb cells. J Biol Chem 266, 12306-12312 (1991)
21. *-ATPase. Biochem Biophys Res Commun 152, 1269-1274 (1988)
22. Sacerdoti D, Escalante B, Abraham NG, McGiff JC, Levere RD and Schwartzman ML: Treatment with tin prevents the development of hypertension in spontaneously hypertensive rats. Science 243, 388-390 (1989)
23. Imaoka S and Funae Y: Hepatic and renal cytochrome P-450s in spontaneously hypertensive rats. Biochim Biophys Acta 1074, 209-213 (1991)
24. Iwai N and Inagami T: Isolation of preferentially expressed genes in the kidneys of hypertensive rats. Hypertension 17, 161-169 (1991)
25. Graser T, Vedernikov YP and Li DS: Study on the mechanism of carbon monoxide induced endothelium-independent relaxation in porcine coronary artery and vein. Biomed Biochim Acta 49, 293-296 (1990)
26. Wang R, Wang Z and Wu L: Carbon monoxide-induced vasorelaxation and the underlying mechanisms. Br J Pharmacol 121, 927-934 (1997)
27. Rapp JP: Dahl salt-susceptible and Dahl salt-resistant rats. A review. Hypertension 4, 753-763 (1982)
28. Makita K, Takahashi K, Karara A, Jacobson HR, Falck JR and Capdevila JH: Experimental and or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet. J Clin Invest 94, 2414-2420 (1994)
29. Nakamura M, Imaoka S, Miura K, Tanaka E, Misawa S and Funae Y: Induction of cytochrome P 450 isozymes in rat renal microsomes by cyclosporin A. Biochem Pharmacol 48, 1743-1746 (1994)
30. Carroll MA, Garcia MP, Falck JR and McGiff JC: Cyclooxygenase dependency of the renovascular actions of cytochrome P450-derived arachidonate metabolites. J Pharmacol Exp Ther 260, 104-109 (1992)
31. Snyder GD, Capdevila J, Chacos N, Manna S and Falck JR: Action of luteinizing hormone-releasing hormone: involvement of novel arachidonic acid metabolites. Proc Natl Acad Sci USA 80, 3504-3407 (1983)
32. Fitzpatrick FA and Murphy RC: Cytochrome P-450 metabolism of arachidonic acid: formation and biological actions of "epoxygenase"-derived eicosanoids. Pharmacol Rev 40, 229-241 (1988)
33. Karara A, Dishman E, Blair I, Falck JR and Capdevila JH: Endogenous epoxyeicosatrienoic acids. Cytochrome P-450 controlled stereoselectivity of the hepatic arachidonic acid epoxygenase. J Biol Chem 264, 19822-19827 (1989)
34. Karara A, Dishman E, Jacobson H, Falck JR and Capdevila JH: Arachidonic acid epoxygenase: Stereochemical analysis of the endogenous epoxyeicosatrienoic acids of human kidney cortex. FEBS Lett 268, 227-230 (1990)
35. +)ATPase. Nature 314, 620-622 (1985)
36. Capdevila JH, Wei S, Yan J, Karara A, Jacobson HR, Falck JR, Guengerich FP and DuBois RN: Cytochrome P-450 arachidonic acid epoxygenase. Regulatory control of the renal epoxygenase by dietary salt loading. J Biol Chem 267, 21720-21726 (1992)
37. Imaoka S, Wedlund PJ, Ogawa H, Kimura S, Gonzalez FJ and Kim HY: Identification of CYP2C 23 expressed in rat kidney as an arachidonic acid epoxygenase. J Pharmacol Exp Ther 267, 1012-1016 (1993)
38. Karara A, Makita K, Jacobson HR, Falck JR, Guengerich FP, DuBois RN and Capdevila JH: Molecular cloning, expression, and enzymatic characterization of the rat kidney cytochrome P-450 arachidonic acid epoxygenase. J Biol Chem 268, 13565-13570 (1993)
39. Campbell WB, Gebremedhin D, Pratt PF and Harder DR: Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ Res 78, 415-423 (1996)
40. Fulton D, Mahboubi K, McGiff JC and Quilley J: Cytochrome P450-dependent effects of bradykinin in the rat heart. Br J Pharmacol 114, 99-102 (1995)
41. + channels in the vasodilator response to bradykinin in the rat heart. Br J Pharmacol 113, 954-958 (1994)
42. Rosolowsky M and Campbell WB: Synthesis of hydroxyeicosatetraenoic (HETEs) and epoxyeicosatrienoic acids (EETs) by cultured bovine coronary artery endothelial cells. Biochim Biophys Acta 1299, 267-277 (1996)
43. Quilley J, Fulton D and McGiff JC: Hyperpolarizing factors. Biochem Pharmacol 54, 1059-1070 (1997)
44. Van de Voorde J and Vanheel B: Influence of cytochrome P-450 inhibitors on endothelium-dependent nitro-L-arginine-resistant relaxation and cromakalim-induced relaxation in rat mesenteric arteries. J Cardiovasc Pharmacol 29, 827-832 (1997)
45. Fukao M, Hattori Y, Kanno M, Sakuma I and Kitabatake A: Evidence against a role of cytochrome P450-derived arachidonic acid metabolites in endothelium-dependent hyperpolarization by acetylcholine in rat isolated mesenteric artery. Br J Pharmacol 120, 439-446 (1997)