Pharmacological characterization of a rat 5-hydroxytryptamine type3 receptor subunit (r5-HT(3A(b)) expressed in Xenopus laevis oocytes

British Journal of Pharmacology

Volumn 124, Issue 8, 1998, Pages 1667-1674

  Mair, Ian D ^a   Lambert, Jeremy J ^a   Yang, Jay ^b   Dempster, John ^c   Peters, John A ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

(+) tubocurarine; 2 methyl 5 HT; 5 HT(3A) receptor subunit; 5 HT3 receptor; 5 hydroxytryptamine (5 HT); Arylbiguanides; Cocaine; Ondansetron

Indexed keywords

1 (3 CHLOROPHENYL)BIGUANIDE; COCAINE; ONDANSETRON; PHENYLBIGUANIDE; RECEPTOR SUBUNIT; SEROTONIN; SEROTONIN 3 RECEPTOR; SEROTONIN DERIVATIVE; TUBOCURARINE CHLORIDE;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; SPECIES DIFFERENCE; VOLTAGE CLAMP; XENOPUS LAEVIS;

ALGORITHMS; ANIMALS; DNA; ELECTROPHYSIOLOGY; HUMANS; MEMBRANE POTENTIALS; MICE; OOCYTES; PATCH-CLAMP TECHNIQUES; RATS; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; XENOPUS LAEVIS;

EID: 0031816512     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702037     Document Type: Article

References (61)

1. 3 receptors. Eur. J. Pharmacol., 296, 277-230.
2. BARNARD, E.A. (1996). The transmitter-gated channels: a range of receptor types and structures. Trends Pharmacol. Sci., 17, 305-309.
3. 3 receptor in mammalian NG108-15 cells. J. Physiol., 490.3, 679-690.
4. s receptor subunit. Mol. Pharmacol., 48, 1054-1062.
5. 3 receptor. J. Neurochem., 64, 1401-1405.
6. 3 receptors in NG 108-15 neuroblastoma x glioma cells: effect of the novel agonist 1-(m-chlorophenyl)-biguanide. Neuropharmacology, 31, 561-564.
7. 3 receptors. J. Neurochem., 65, 104-110.
8. 3A). J. Physiol., 507.3, 653-665.
9. 3 receptor in human forebrain. Neuropharmacology, 32, 1325-1331.
10. 3 receptors in three isolated preparations derived from guinea-pig tissues. Br. J. Pharmacol., 101, 591-598.
11. 3 receptors. In vitro and in vivo characterization. Eur. J. Pharmacol., 316, 195-203.
12. DEMPSTER, J. (1997). A new version of the Strathclyde Electrophysiology Software package running within the Microsoft Windows environment. J. Physiol., 504, P.57 (abstract).
13. 3R-A subunit expressed in Xenopus laevis oocytes. Neuropharmacology, 33, 473-482.
14. 3 receptors. J. Med. Chem., 39, 4017-4026.
15. 3 receptor stably expressed in HEK 293 cells. Br. J. Pharmacol., 114, 1211-1221.
16. 2+ levels. Receptors Channels, 3, 83-88.
17. 3 receptors provides new insights into their maturation and structure. J. Biol. Chem., 270, 6056-6061.
18. HALL, J.M., CAULFIELD, M.P., WATSON, S.P. & GUARD, S. (1993). Receptor subtypes or species homologs-relevance to drug discovery. Trends Pharmacol. Sci., 14, 376-383.
19. 1D-like pharmacological specificity. Biophys. Biochem. Res. Commun., 185, 517-523.
20. 3 receptor-A subunit. Eur. J. Pharmacol., 245, 187-192.
21. 3R-As) subunit stably expressed in HEK 293 cells. Br. J. Pharmacol., 118, 1237-1245.
22. HOYER, D. & MARTIN, G.R. (1997). 5-HT receptor classification and nomenclature: Towards a harmonization with the human genome. Neuropharmacology, 36, 419-428.
23. HUSSY, N., LUKAS, W. & JONES, K.A. (1994). Functional properties of a cloned 5-hydroxytryptamine ionotropic receptor subunit: comparison with native mouse receptors. J. Physiol., 481.2, 1311-1323.
24. IRELAND, S.J. & TYERS, M.B. (1987). Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve. Br. J. Pharmacol., 90, 229-238.
25. 3 receptor subunit. Neuroreport, 5, 121-124.
26. 3 receptor reveals species-specific sensitivity of curare antagonism. Soc. Neurosci. Abs., 18, 249.
27. 3, receptors in the rat hippocampal dentate gyrus-a patch-clamp study. J. Neurophysiol., 71, 1935-1947.
28. 3 receptor-binding sites in rabbit ileum-comparison with those in rat ileum and rat brain. Neurochem. Int., 19, 389-396.
29. 3 receptor agonist. Eur. J. Pharmacol., 182, 193-197.
30. 3 receptor cDNA and its splice variants from guinea-pig. Mol. Pharmacol., 53, 202-212.
31. 3 receptors of rabbit, mouse and guinea pig nodose ganglion neurones. Br. J. Pharmacol., 104, 68P.
32. 3 receptor subunit derived from rat superior cervical ganglion. Br. J. Pharmacol., 119, 293P.
33. 3 receptor, a serotonin-gated ion channel. Science, 254, 432-437.
34. McMAHON, L.L. & KAUER, J.A. (1997). Hippocampal interneurons are excited via serotonin-gated ion channels. J. Neurophysiol., 78, 2493-2502.
35. 3 receptor splice variants in the rat. J. Neurochem., 65, 475-483.
36. 3 receptor: heterogeneity in distribution and function among species. Mol. Pharmacol., 48, 407-416.
37. MORAIN, P., ABRAHAM, C., PORTEVIN, B. & DENANTEUIL, G. (1994). Biguanide derivatives: Agonist pharmacology at 5-hydroxytryptamine type 3 receptors in vitro. Mol. Pharmacol., 46, 732-742.
38. 3 receptor mediated electrical responses in cultured mouse neuroblastoma cells. Neuropharmacology, 27, 301-307.
39. NEWBERRY, N.R. & GILBERT, M.J. (1989). 5-Hydroxytryptamine evokes three distinct responses in the rat superior cervical ganglion in vitro. Eur. J. Pharmacol., 162, 197-205.
40. 3 receptors of the rat, mouse and guinea-pig superior cervical ganglion may be different. Br. J. Pharmacol., 102, 615-620.
41. 1B receptors. Nature. 360, 161-163.
42. ORTELLS, M.O. & LUNT, G.G. (1995). Evolutionary history of the ligand-gated ion-channel superfamily of receptors. Trends Neurosci., 18, 121-127.
43. PETERS, J.A., HOPE, A.G., SUTHERLAND, L. & LAMBERT, J.J. (1997). Recombinant 5-hydroxytryptamine receptors. In Recombinant Cell Surface Receptors: Focal Point for Therapeutic Intervention, ed. Brown, M.J. pp. 119-154. Landes, Austin.
44. 3 receptor mediated currents in murine N1E-115 neuroblastoma cells by (+)-tubocurarine. Neurosci. Lett., 110, 107-112.
45. 3 receptor mediated electrical responses in nodose ganglion neurones and clonal neuroblastoma cells maintained in culture. In Serotonin: Molecular Biology, Receptors and Functional Effects, eds. Fozard, J.R. & Saxena, P.R. pp. 84-94, Basle, Birkhauser.
46. 3 receptors. Trends Pharmacol. Sci., 13, 391-397.
47. 3 receptor antagonism on hippocampal cellular activity in the freely moving rat. J. Neurophysiol., 77, 517-521.
48. 3 receptors in developing visual cortex. J. Neurosci., 17, 8353-8362.
49. ROPERT, N. & GUY N. (1991). Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro. J. Physiol., 441, 121-136.
50. 3 receptors in N1E-115 neuroblastoma cells. Br. J. Pharmacol, 104, 536-540.
51. 3 receptors in rat lateral amygdala. Neuron. 8, 199-203.
52. 3 receptors mediate two distinct depolarizing responses in rat dorsal root ganglion neurones. Brain Res., 511, 71-79.
53. 3 receptors expressed in Xenopus oocytes differ form homopentameric receptors. J. Neurochem, 69, 1318-1321.
54. 3 receptor by full and partial agonists. Br. J. Pharmacol., 117, 839-846.
55. 3 receptors. Eur. J. Pharmacol., 322, 229-233.
56. VANHOUTTE, P.M., HUMPHREY, P.P.A. & SPEDDING, M. (1996). International Union of Pharmacology recommendations for new receptor subtypes. Pharmac. Rev., 48, 1-2.
57. WALLIS, D.I., STANSFELD, C.E. & NASH, H L. (1982). Depolarizing responses recorded from nodose ganglion neurones of the rabbit evoked by 5-hydroxytryptamine and other substances. Neuropharmacology, 21, 31-40.
58. 3 receptor gene and functional expression of 2 splice variants. Mol. Brain Res., 26, 233-241.
59. 3H]RS-42358-197. J. Neurochem., 60, 921-930.
60. 3 receptors mediate rapid responses in cultured hippocampus and a clonal cell line. Neuron. 1, 615-621.
61. 3 receptor channels in dissociated rat superior cervical-ganglion neurons. J. Physiol., 448, 237-256.