Hippocampal interneurons are excited via serotonin-gated ion channels

Journal of Neurophysiology

Volumn 78, Issue 5, 1997, Pages 2493-2502

  McMahon, Lori L ^a   Kauer, Julie A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 2 METHYLSEROTONIN; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 6,7 DINITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR ANTAGONIST; GLUTAMATE RECEPTOR ANTAGONIST; ION CHANNEL; METOCLOPRAMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PICROTOXIN; SEROTONIN; SEROTONIN 3 RECEPTOR; TETRODOTOXIN; TROPISETRON; TUBOCURARINE CHLORIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HIPPOCAMPUS; INTERNEURON; MALE; NERVE CELL EXCITABILITY; NEUROTRANSMISSION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SEROTONINERGIC TRANSMISSION; SYNAPTIC TRANSMISSION;

EID: 0030657685     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1997.78.5.2493     Document Type: Article

References (53)

1. ACSADY, L., HALASY, K. F., AND FREUND, T. F. Calretinin is present in non-pyramidal cells of the rat hippocampus. III. Their inputs from the median raphe and medial septal nuclei. Neuroscience 52: 829-841, 1993.
2. ANDRADE, R. AND NICOLL, R. A. Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro. J. Physiol. (Lond.) 394: 99-124, 1987.
3. ASCHER, P. AND NOWAK, L. The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurons in culture. J. Physiol. (Lond.) 399: 247-266, 1988.
4. BERGLES, D. E., DOZE, V. A., MADISON, D. V., AND SMITH, S. J. Excitatory actions of norepinephrine on multiple classes of hippocampal CA1 interneurons. J. Neurosci. 16: 572-585, 1996.
5. BORMANN, J. Memantine is a potent blocker of N-methyl-D-aspartate (NMDA) receptor channels. Eur. J. Pharmacol. 166: 591-592, 1989.
6. BLISS, T.V.P. AND COLLINGRIDGE, G. L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361: 31-39, 1993.
7. BUHL, E. H., HALASY, K., AND SOMOGYI, P. Diverse sources of hippocampal unitary inhibitory postsynaptic potentials and the number of synaptic release sites. Nature 368: 823-828, 1994.
8. COBB, S. R., BUHL, E. H., HALASY, K., PAULSEN, O., AND SOMOGYI, P. Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons. Nature 378: 75-78, 1995.
9. 3 receptors are membrane ion channels. Nature 339: 706-709, 1989.
10. DOZE, V. A., COHEN, G. A., AND MADISON, D. V. Synaptic localization of adrenergic disinhibition in the rat hippocampus. Neuron 6: 889-900, 1991.
11. FENWICK, E. M., MARTY, A., AND NEHER, E. A patch-clamp study of bovine chromaffin cells and of the sensitivity to acetylcholine. J. Physiol. (Lond.) 331: 577-597, 1982.
12. FRASER, D. D. AND MACVICAR, B. A. Low threshold transient calcium current in rat hippocampal lacunosum-moleculare interneurons: kinetics and modulation by neurotransmitters. J. Neurosci. 11: 2812-2820, 1991.
13. FREUND, T. F. AND ANTAL, M. GABA-containing neurons in the septum control inhibitory interneurons in the hippocampus. Nature 336: 170-173, 1988.
14. FREUND, T. F. AND BUZSAKI, G. Interneurons of the hippocampus. Hippocampus 6: 347-470, 1996.
15. FREUND, T. F., GULYAS, A. I., ACSADY, L., GORCS, T., AND TOTH, K. Serotonergic control of the hippocampus via local inhibitory interneurons. Proc. Natl. Acad. Sci. USA 87: 8501-8505, 1990.
16. 3 receptors in PC12 cells treated with NGF and 8-Br-cAMP. J. Neurophysiol 67: 812-819, 1992.
17. 2+ levels. Receptors Channels 3: 83-88, 1995.
18. GLAUM, S. R., BROOKS, P. A., SPYER, K. M., AND MILLER, R. J. 5-Hydroxytryptamine-3 receptors modulate synaptic activity in the rat nucleus tractus solitarius in vitro. Brain Res. 589: 62-68, 1992.
19. 2+ permeability of cloned and native 5-hydroxytryptarnine type 3 receptors. Mol. Pharmacol. 46: 1120-1128, 1994.
20. HIGASHI, H. AND NISHI, S. 5-Hydroxytryptamine receptors of visceral primary afferent neurons on rabbit nodose ganglia. J. Physiol. (Lond.) 323: 543-567, 1982.
21. 3 receptor channel. Annu. Rev. Physiol. 57: 447-468, 1995.
22. JENKINSON, D. H. The antagonism between tubocurarine and substances which depolarize the motor end-plate. J. Physiol. (Lond.) 152: 309-324, 1960.
23. 3 subtype of serotonin receptor in primary cultures of rodent hippocampus. Neurosci. Lett. 174: 133-136, 1994.
24. 3 receptors in the rat hippocampal dentate gyrus: a patch clamp study. J. Neurophysiol. 71: 1935-1947, 1994.
25. LABEDA, F. J., HABLITZ, J. J., AND JOHNSTON, D. Antagonism of GABA-mediated responses by d-tubocurarine in hippocampal neurons. J. Neurophysiol. 48: 622-632, 1982.
26. LACAILLE, J. C. AND SCHWARTZKROIN, P. A. Stratum lacunosum-moleculare interneurons of hippocampal CA1 region. I. Intracellular response characteristics, synaptic responses, and morphology. J. Neurosci. 8: 1400-1410, 1988.
27. 3 receptors in clonal cell lines studied by patch-clamp techniques. Br. J. Pharmacol. 97: 27-40, 1989.
28. MACCAFERRI, G. AND MCBAIN, C. J. Passive propagation of LTD to stratum oriens-alveus inhibitory neurons modulates the temporoammonic input to the hippocampal CA1 region. Neuron 15: 137-145, 1995.
29. 3 receptor, a serotonin-gated ion channel. Science 254: 432-437, 1991.
30. 2+ of NMDA responses in spinal cord neurons. Nature 309: 261-263, 1984.
31. MCBAIN, C. J., DICHIARA, T. J., AND KAUER, J. A. Activation of metabotropic glutamate receptors differentially affects two classes of hippocampal interneurons and potentiates excitatory synaptic transmission. J. Neurosci. 14: 4433-4445, 1994.
32. MCMAHON, L. L. AND KAUER, J. A. Hippocampal interneurons express a novel form of synaptic plasticity. Neuron 18: 295-305, 1997.
33. MORALES, M., BATTENBERG, E., DE LECEA, L., AND BLOOM, F. E. The type 3 serotonin receptor is expressed in a subpopulation of GABAergic neurons in the rat neocortex and hippocampus. Brain Res. 731: 199-202, 1996.
34. 3 receptors in cultured mouse neuroblastoma cells. J. Physiol. (Lond.) 411: 257-269, 1989.
35. NOWAK, L., BREGESTOVSKI, P., AND ASCHER, P. Magnesium gates glutamate-activated channels in mouse central neurons. Nature 307: 462-465, 1984.
36. PETERS, J. A. AND USHERWOOD, P.N.R. 5-Hydroxytryptamine responses of murine neuroblastoma cells: ions and putative antagonists. Br. J. Pharmacol. 80: 523P, 1983.
37. 3 receptor-induced currents in N1E-115 neuroblastoma cells. Eur. J. Pharmacol. 151: 491-495, 1988.
38. 3 receptors. Trends Pharmacol. Sci. 13: 391-397, 1992.
39. RICHARDSON, B. P., ENGEL, G., DONATSCH, P., AND STADLER, P. A. Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs. Nature 316: 126-131, 1985.
40. ROPERT, N. AND GUY, N. Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro. J. Physiol. (Lond.) 441: 121-136, 1991.
41. ROTH, B. L. Multiple serotonin receptors: clinical and experimental aspects. Ann. Clin. Psychiatry 6: 67-78, 1994.
42. 3 receptor. J. Neurophysiol. 65: 630-638, 1991.
43. 2 receptor activation in hippocampus CA1 region. Proc. Soc. Neurosci. Abstr. 22: 1775, 1996.
44. 3 receptors in rat amygdala. Neuron 8: 199-203, 1992.
45. 3 receptor mRNA. Proc. Natl. Acad. Sci. USA 90: 1430-1434, 1993.
46. 3 receptor-gated channel events resolved in N1E-115 mouse neuroblastoma cells. Biochem. Biophys. Res. Commun. 199: 227-233, 1994.
47. WOTRING, V. E. AND YOON, K.-W. The inhibitory effects of nicotinic antagonists on currents elicited by GABA in rat hippocampal neurons. Neuroscience 67: 293-300, 1995.
48. 3 receptors mediate rapid response in cultured hippocampus and a clonal cell line. Neuron 1: 615-621, 1988.
49. YAKEL, J. L., TRUSSELL, L. O., AND JACKSON, M. B. Three serotonin responses in cultured mouse hippocampal and striatal neurons. J. Neurosci. 8: 1273-1285, 1988.
50. 3 receptor. Brain Res. 533: 46-52, 1990.
51. YAKEL, J. L., LAGRUTTA, A., ADELMAN, J. P., AND NORTH, R. A. Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes. Proc. Natl. Acad. Sci. USA 90: 5030-5033, 1993.
52. YANG, J. Ion permeation through 5-hydroxytryptamine-gated channels in neuroblastoma N18 cells. J. Gen. Physiol. 96: 1177-1198, 1990.
53. 3 receptor channels in dissociated rat superior cervical ganglion neurons. J. Physiol. (Lond.) 448: 237-256, 1992.