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Volumn 28, Issue 5, 1998, Pages 493-506

Interlaboratory comparison of the assessment of P450 activities in human hepatic microsomal samples

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 ISOENZYME; LIVER ENZYME;

EID: 0031810018     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/004982598239416     Document Type: Article
Times cited : (27)

References (49)
  • 2
    • 0024506260 scopus 로고
    • Comparison of caffeine metabolism by slices, microsomes and hepatocyte cultures from adult human liver
    • BERTHOU, F., RATANASAVANH, D., RICHE, C., PICART, D., VOIRIN, T. and GUILLOUZO, A., 1989, Comparison of caffeine metabolism by slices, microsomes and hepatocyte cultures from adult human liver. Xenobiotica, 19, 401-417.
    • (1989) Xenobiotica , vol.19 , pp. 401-417
    • Berthou, F.1    Ratanasavanh, D.2    Riche, C.3    Picart, D.4    Voirin, T.5    Guillouzo, A.6
  • 5
    • 0025733250 scopus 로고
    • Role of P450IID6, the target of the sparteine-debrisoquin oxidation polymorphism, in the metabolism of imipramine
    • BROSEN, K., ZEUGIN, T. and MEYER, U. S., 1991, Role of P450IID6, the target of the sparteine-debrisoquin oxidation polymorphism, in the metabolism of imipramine. Clinical Pharmacology and Therapeutics, 49, 609-617.
    • (1991) Clinical Pharmacology and Therapeutics , vol.49 , pp. 609-617
    • Brosen, K.1    Zeugin, T.2    Meyer, U.S.3
  • 6
    • 0024603850 scopus 로고
    • Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P45011IA gene subfamily
    • COMBALBERT, J., FABRE, I., FABRE, G., DALET, I., DERANCOURT, J., CANO, J. P. and MAUREL, P., 1989, Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P45011IA gene subfamily. Drug Metabolism and Disposition, 17, 197-207.
    • (1989) Drug Metabolism and Disposition , vol.17 , pp. 197-207
    • Combalbert, J.1    Fabre, I.2    Fabre, G.3    Dalet, I.4    Derancourt, J.5    Cano, J.P.6    Maurel, P.7
  • 7
    • 0003419266 scopus 로고    scopus 로고
    • in press
    • COMMITTEE FOR PROPRIETARY MEDICINAL PRODUCTS (CPMP), EUROPEAN AGENCY FOR THE EVALUATION OF MEDICINAL PRODUCTS: HUMAN MEDICINES EVALUATION UNIT, 1997, Note for guidance on the investigation of drug interactions (in press).
    • (1997) Note for Guidance on the Investigation of Drug Interactions
  • 8
    • 0029587052 scopus 로고
    • Mechanism of cytochrome P450 2D6-catalyzed sparteine metabolism in humans
    • EBNER, T., MEESE, C. O. and EICHELBAUM, M., 1995. Mechanism of cytochrome P450 2D6-catalyzed sparteine metabolism in humans. Molecular Pharmacology 48, 1078-1086.
    • (1995) Molecular Pharmacology , vol.48 , pp. 1078-1086
    • Ebner, T.1    Meese, C.O.2    Eichelbaum, M.3
  • 10
    • 0027425282 scopus 로고
    • Saccharomyces cerevisiae: An alternative source for human microsomal liver enzymes and its use in drug interaction studies
    • EUGSTER, H. P. and SENGSTAG, C., 1993, Saccharomyces cerevisiae: an alternative source for human microsomal liver enzymes and its use in drug interaction studies. Toxicology, 82, 61-73.
    • (1993) Toxicology , vol.82 , pp. 61-73
    • Eugster, H.P.1    Sengstag, C.2
  • 12
    • 0029790347 scopus 로고    scopus 로고
    • Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cDNA-expressed human cytochrome P450
    • GHOSAL, A., SATOH, H., THOMAS, P. E., BUSH, E. and MOORE, D., 1996, Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cDNA-expressed human cytochrome P450. Drug Metabolism and Disposition, 24, 940-947.
    • (1996) Drug Metabolism and Disposition , vol.24 , pp. 940-947
    • Ghosal, A.1    Satoh, H.2    Thomas, P.E.3    Bush, E.4    Moore, D.5
  • 13
    • 0023876472 scopus 로고
    • Phenacetin O-deethylation by human liver microsomes: Kinetics and popranolol inhibition
    • GILLAM, E. M. and REILLY, P. E., 1988, Phenacetin O-deethylation by human liver microsomes: kinetics and popranolol inhibition. Xenobiotica, 18, 95-104.
    • (1988) Xenobiotica , vol.18 , pp. 95-104
    • Gillam, E.M.1    Reilly, P.E.2
  • 14
    • 0028234586 scopus 로고
    • Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily
    • GORSKI, J. C., HALL, S. D., JONES, D. R., VANDENBRANDEN, M. and WRIGHTON, S. A., 1994, Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily. Biochemical Pharmacology, 47, 1643-1653.
    • (1994) Biochemical Pharmacology , vol.47 , pp. 1643-1653
    • Gorski, J.C.1    Hall, S.D.2    Jones, D.R.3    Vandenbranden, M.4    Wrighton, S.A.5
  • 15
    • 0023273657 scopus 로고
    • Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies
    • GRANT, D M., CAMPBELL, M. E., TANG, B. K. and KALOW, W., 1987, Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies, Biochemical Pharmacology, 36, 1251-1260.
    • (1987) Biochemical Pharmacology , vol.36 , pp. 1251-1260
    • Grant, D.M.1    Campbell, M.E.2    Tang, B.K.3    Kalow, W.4
  • 17
    • 0027536616 scopus 로고
    • Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes
    • HARRELL, A. W., WHEELER, S. M., PENNICK, M., CLARKE, S. E and CHENERY, R. J., 1993, Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes. Drug Metabolism and Disposition, 21, 18-23.
    • (1993) Drug Metabolism and Disposition , vol.21 , pp. 18-23
    • Harrell, A.W.1    Wheeler, S.M.2    Pennick, M.3    Clarke, S.E.4    Chenery, R.J.5
  • 18
    • 0027957132 scopus 로고
    • Metabolism of taxol by human hepatic microsomes and liver slices: Participation of cytochrome P450 3A4 and an unknown P450 enzyme
    • HARRIS, J. W., RAHMAN, A., KIM, B. R., GUENGERICH, F. P. and COLLINS, J. M., 1994, Metabolism of taxol by human hepatic microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzyme. Cancer Research, 54, 4026-4035.
    • (1994) Cancer Research , vol.54 , pp. 4026-4035
    • Harris, J.W.1    Rahman, A.2    Kim, B.R.3    Guengerich, F.P.4    Collins, J.M.5
  • 20
    • 0023711819 scopus 로고
    • Metabolism of diazepam in vitro by human liver. Independent variability of N-demethylation and C3-hydroxylation
    • INABA, T., TAIT, A., NAKANO, M., MAHON, W. A. and KALOW, W., 1988, Metabolism of diazepam in vitro by human liver. Independent variability of N-demethylation and C3-hydroxylation. Drug Metabolism and Disposition, 16, 605-608.
    • (1988) Drug Metabolism and Disposition , vol.16 , pp. 605-608
    • Inaba, T.1    Tait, A.2    Nakano, M.3    Mahon, W.A.4    Kalow, W.5
  • 22
    • 0028600597 scopus 로고
    • The importance of substrate concentration in determining cytochromes P450 therapeutically relevant in vivo
    • KATO, R. and YAMAZOE, Y., 1994, The importance of substrate concentration in determining cytochromes P450 therapeutically relevant in vivo. Pharmacogenetics, 4, 359-362.
    • (1994) Pharmacogenetics , vol.4 , pp. 359-362
    • Kato, R.1    Yamazoe, Y.2
  • 23
    • 0026324040 scopus 로고
    • Bufuralol, dextromethorphan, and debrisoquine as prototype substrates for human P450IID6
    • KRONBACH, T., 1991, Bufuralol, dextromethorphan, and debrisoquine as prototype substrates for human P450IID6. Methods in Enzymology, 206, 509-517.
    • (1991) Methods in Enzymology , vol.206 , pp. 509-517
    • Kronbach, T.1
  • 26
    • 0029775813 scopus 로고    scopus 로고
    • Chlorzoxazone: An in vitro and in vivo substrate probe for liver CYP2E1
    • LUCAS, D., MENEZ, J. F. and BERTHOU, F., 1996, Chlorzoxazone: an in vitro and in vivo substrate probe for liver CYP2E1. Methods in Enzymology, 272, 115-123.
    • (1996) Methods in Enzymology , vol.272 , pp. 115-123
    • Lucas, D.1    Menez, J.F.2    Berthou, F.3
  • 27
    • 0023873591 scopus 로고
    • Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations
    • MINERS, J. O., SMITH, K. J., ROBSON, R. A., MCMANUS, M. E., VERONESE, M. E. and BIRKETT, D. J., 1988, Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations. Biochemical Pharmacology, 37, 1137-1144.
    • (1988) Biochemical Pharmacology , vol.37 , pp. 1137-1144
    • Miners, J.O.1    Smith, K.J.2    Robson, R.A.3    Mcmanus, M.E.4    Veronese, M.E.5    Birkett, D.J.6
  • 31
    • 0025670512 scopus 로고
    • Expression of human liver cytochrome P450 IIIA4 in yeast. A functional model for the hepatic enzyme
    • RENAUD, J. P., CULLIN, C., POMPON, D., BEAUNE, P. and MANSUY, D., 1990, Expression of human liver cytochrome P450 IIIA4 in yeast. A functional model for the hepatic enzyme. European Journal of Biochemistry, 194, 889-896.
    • (1990) European Journal of Biochemistry , vol.194 , pp. 889-896
    • Renaud, J.P.1    Cullin, C.2    Pompon, D.3    Beaune, P.4    Mansuy, D.5
  • 32
    • 0028114740 scopus 로고
    • Use of in vitro human metabolism studies in drug development. An industrial perspective
    • RODRIGUES, A. D., 1994, Use of in vitro human metabolism studies in drug development. An industrial perspective. Biochemical Pharmacology, 48, 2147-2156.
    • (1994) Biochemical Pharmacology , vol.48 , pp. 2147-2156
    • Rodrigues, A.D.1
  • 33
    • 0023226239 scopus 로고
    • Interlaboratory comparison of total cytochrome P-450 and protein determinations in rat liver microsomes. Reinvestigation of assay conditions
    • RUTTEN, A. A., FALKE, H. E., CATSBURG, J. F., TOPP, R., BLAAUBOER, B. J., VAN HOLSTEIJN, I., DOOM, L. and VAN LEEUWEN, F. X., 1987, Interlaboratory comparison of total cytochrome P-450 and protein determinations in rat liver microsomes. Reinvestigation of assay conditions. Archives of Toxicology, 61, 27-33.
    • (1987) Archives of Toxicology , vol.61 , pp. 27-33
    • Rutten, A.A.1    Falke, H.E.2    Catsburg, J.F.3    Topp, R.4    Blaauboer, B.J.5    Van Holsteijn, I.6    Doom, L.7    Van Leeuwen, F.X.8
  • 35
    • 0023687412 scopus 로고
    • A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking
    • SESARDIC, D., BOOBIS, A. R., EDWARDS, R. J. and DAVIES, D. S., 1988, A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking. British Journal of Clinical Pharmacology, 26, 363-372.
    • (1988) British Journal of Clinical Pharmacology , vol.26 , pp. 363-372
    • Sesardic, D.1    Boobis, A.R.2    Edwards, R.J.3    Davies, D.S.4
  • 37
    • 0025364520 scopus 로고
    • Differential expression and regulation of members of the cytochrome P450IA gene subfamily in human tissues
    • SESARDIC, D., PASANEN, M., PELKONEN, O. and BOOBIS, A. R., 1990b, Differential expression and regulation of members of the cytochrome P450IA gene subfamily in human tissues. Carcinogenesis, 11, 1183-1188.
    • (1990) Carcinogenesis , vol.11 , pp. 1183-1188
    • Sesardic, D.1    Pasanen, M.2    Pelkonen, O.3    Boobis, A.R.4
  • 38
    • 0028838715 scopus 로고
    • Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey
    • SHARER, J. E., SHIPLEY, L. A., VANDENBRANDEN, M. R., BINKLEY, S. N. and WRIGHTON, S. A., 1995, Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey. Drug Metabolism and Disposition, 23, 1231-1241.
    • (1995) Drug Metabolism and Disposition , vol.23 , pp. 1231-1241
    • Sharer, J.E.1    Shipley, L.A.2    Vandenbranden, M.R.3    Binkley, S.N.4    Wrighton, S.A.5
  • 39
    • 0030959377 scopus 로고    scopus 로고
    • Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys and humans
    • SHIMADA, S., MIMURA, M., INOUE, K., NAKAMARA, S., ODA, H., OHMORI, S. and YAMAZAKI, H., 1997, Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys and humans. Archives of Toxicology, 71, 401-108.
    • (1997) Archives of Toxicology , vol.71 , pp. 401-1108
    • Shimada, S.1    Mimura, M.2    Inoue, K.3    Nakamara, S.4    Oda, H.5    Ohmori, S.6    Yamazaki, H.7
  • 40
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • SHIMADA, T., YAMAZAKI, H., MIMURA, M., INUI, Y. and GUENGERICH, F. P., 1994, Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. Journal of Pharmacology and Experimental Therapeutics, 270, 414-423.
    • (1994) Journal of Pharmacology and Experimental Therapeutics , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 43
    • 0029683030 scopus 로고    scopus 로고
    • The clinical pharmacologist in drug regulation: The US perspective
    • TEMPLE, R. J., 1996, The clinical pharmacologist in drug regulation: the US perspective. British Journal of Clinical Pharmacology, 42, 73-79.
    • (1996) British Journal of Clinical Pharmacology , vol.42 , pp. 73-79
    • Temple, R.J.1
  • 44
    • 0029760232 scopus 로고    scopus 로고
    • Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes
    • TRANSON, C., LECOEUR, S., LEEMANN, T., BEAUNE, P. and DAYER, P., 1996, Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes. European Journal of Clinical Pharmacology, 51, 79-85.
    • (1996) European Journal of Clinical Pharmacology , vol.51 , pp. 79-85
    • Transon, C.1    Lecoeur, S.2    Leemann, T.3    Beaune, P.4    Dayer, P.5
  • 49
    • 0031034166 scopus 로고    scopus 로고
    • Effects of freezing, thawing, and storage of human liver samples on the microsomal contents and activities of cytochrome P450 enzymes
    • YAMAZAKI, H., INOUE, K., TURVY, C. G., GUENGERICH, F. P. and SHIMADA, T., 1997, Effects of freezing, thawing, and storage of human liver samples on the microsomal contents and activities of cytochrome P450 enzymes. Drug Metabolism and Disposition, 25, 168-174.
    • (1997) Drug Metabolism and Disposition , vol.25 , pp. 168-174
    • Yamazaki, H.1    Inoue, K.2    Turvy, C.G.3    Guengerich, F.P.4    Shimada, T.5


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