Dual effects of anti-inflammatory 2-arylpropionic acid derivatives on a major isoform of human liver 3α-hydroxysteroid dehydrogenase

Biological and Pharmaceutical Bulletin

Volumn 21, Issue 11, 1998, Pages 1148-1153

  Yamamoto, Tomohiro ^a   Matsuura, Kazuya ^a   Shintani, Syunichi ^a   Hara, Akira ^a   Miyabe, Yoshiyuki ^b   Sugiyama, Tadashi ^c   Katagiri, Yoshihiro ^c  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b GIFU PREFECTURAL TAJIMI HOSPITAL   (Japan)

^c GIFU UNIVERSITY HOSPITAL   (Japan)

Author keywords

3 Hydroxysteroid dehydrogenase; Activation; Aldo keto reductase family; Anti inflammatory drug; Stereoselectivity

Indexed keywords

3ALPHA HYDROXYSTEROID DEHYDROGENASE; AROMATIC HYDROCARBON; ARYLPROPIONIC ACID DERIVATIVE; BILE ACID; FENOPROFEN; FLURBIPROFEN; IBUPROFEN; KETONE; KETOPROFEN; NAPROXEN; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STEROID HORMONE; SUPROFEN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; MAMMAL; STEREOCHEMISTRY;

EID: 0031793671     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.21.1148     Document Type: Article

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