Lu 25-109, a combined m1 agonist and m2 antagonist, modulates regulated processing of the amyloid precursor protein of Alzheimer's disease

Journal of Neural Transmission

Volumn 105, Issue 8-9, 1998, Pages 1029-1043

  Muller D ^a   Wiegmann, H ^a   Langer, U ^a   Moltzen Lenz, S ^b   Nitsch, R M ^a,c  

^a UNIVERSITY OF HAMBURG   (Germany)

^b H LUNDBECK A S   (Denmark)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Acetylcholine; Alzheimer's disease; Amyloid; Brain slices; Muscarinic receptors

Indexed keywords

5 (2 ETHYL 2H TETRAZOL 5 YL) 1 METHYL 1,2,3,6 TETRAHYDROPYRIDINE MALEATE; ALVAMELINE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CARBACHOL; MUSCARINIC M1 RECEPTOR; MUSCARINIC M1 RECEPTOR AGONIST; MUSCARINIC M2 RECEPTOR; MUSCARINIC M2 RECEPTOR ANTAGONIST; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; GENETIC TRANSFECTION; HIPPOCAMPUS; HUMAN; HUMAN CELL; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; RAT;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE; HIPPOCAMPUS; HUMANS; MALE; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PYRIDINES; RATS; RATS, INBRED LEW; TETRAZOLES; TRANSFECTION;

EID: 0031768806     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007020050110     Document Type: Article

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