-
1
-
-
0020597565
-
Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation
-
Samuelsson B. Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 1983; 220:568-75.
-
(1983)
Science
, vol.220
, pp. 568-575
-
-
Samuelsson, B.1
-
2
-
-
0023818258
-
Metabolism of leukotriene E4 in isolated rat hepatocytes. Identification of beta-oxidation products of sulfidopeptide leukotrienes
-
Stene DO, Murphy RC. Metabolism of leukotriene E4 in isolated rat hepatocytes. Identification of beta-oxidation products of sulfidopeptide leukotrienes. J Biol Chem 1988; 263:2773-8.
-
(1988)
J Biol Chem
, vol.263
, pp. 2773-2778
-
-
Stene, D.O.1
Murphy, R.C.2
-
3
-
-
0025869402
-
Role of phospholipase in generating lipid second messengers in signal transduction
-
Dennis EA, Rhee SG, Billah MM, Hannun YA. Role of phospholipase in generating lipid second messengers in signal transduction. Faseb J 1991; 5:2068-77.
-
(1991)
Faseb J
, vol.5
, pp. 2068-2077
-
-
Dennis, E.A.1
Rhee, S.G.2
Billah, M.M.3
Hannun, Y.A.4
-
4
-
-
0027519767
-
Redistribution of 5-lipoxygenase and cytosolic phospholipase A2 to the nuclear fraction upon macrophage activation
-
Peters-Golden M, McNish RW. Redistribution of 5-lipoxygenase and cytosolic phospholipase A2 to the nuclear fraction upon macrophage activation. Biochem Biophys Res Commun 1993; 196:147-53.
-
(1993)
Biochem Biophys Res Commun
, vol.196
, pp. 147-153
-
-
Peters-Golden, M.1
McNish, R.W.2
-
5
-
-
0029015335
-
Mutations at the c-terminal isoleucine and other potential iron ligands of 5-lipoxygenase
-
Hammarberg T, Zhang YY, Lind B, Radmark O, Samuelsson B. Mutations at the c-terminal isoleucine and other potential iron ligands of 5-lipoxygenase. Eur J Biochem 1995; 230:401-7.
-
(1995)
Eur J Biochem
, vol.230
, pp. 401-407
-
-
Hammarberg, T.1
Zhang, Y.Y.2
Lind, B.3
Radmark, O.4
Samuelsson, B.5
-
6
-
-
0001488205
-
Characterization of the human 5-lipoxygenase gene
-
Funk CD, Hoshiko S, Matsumoto T, Radmark O, Samuelsson B. Characterization of the human 5-lipoxygenase gene. Proc Natl Acad Sci USA 1989; 86:2587-91.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 2587-2591
-
-
Funk, C.D.1
Hoshiko, S.2
Matsumoto, T.3
Radmark, O.4
Samuelsson, B.5
-
7
-
-
0026358029
-
LTB4 and PAF in the cytokine network
-
Rola-Pleszczynski M. LTB4 and PAF in the cytokine network. Adv Exp Med Biol 1991; 314:205-21.
-
(1991)
Adv Exp Med Biol
, vol.314
, pp. 205-221
-
-
Rola-Pleszczynski, M.1
-
8
-
-
0022641518
-
Inhalation challenge with sulfidopeptide leukotrienes in human subjects
-
Drazen JM. Inhalation challenge with sulfidopeptide leukotrienes in human subjects. Chest 1986; 89:414-9.
-
(1986)
Chest
, vol.89
, pp. 414-419
-
-
Drazen, J.M.1
-
9
-
-
0029739085
-
Leukotriene antagonists and synthesis inhibitors: New directions in asthma therapy
-
Holgate ST, Bradding P, Sampson AP. Leukotriene antagonists and synthesis inhibitors: new directions in asthma therapy. J Allergy Clin Immunol 1996; 98:1-13.
-
(1996)
J Allergy Clin Immunol
, vol.98
, pp. 1-13
-
-
Holgate, S.T.1
Bradding, P.2
Sampson, A.P.3
-
10
-
-
0018381379
-
Differential effects of a partially purified preparation of slow-reacting substance of anaphylaxis on guinea pig tracheal spirals and parenchymal strips
-
Drazen JM, Lewis RA, Wasserman SI, Orange RP, Austen KF. Differential effects of a partially purified preparation of slow-reacting substance of anaphylaxis on guinea pig tracheal spirals and parenchymal strips. J Clin Invest 1979; 63:1-5.
-
(1979)
J Clin Invest
, vol.63
, pp. 1-5
-
-
Drazen, J.M.1
Lewis, R.A.2
Wasserman, S.I.3
Orange, R.P.4
Austen, K.F.5
-
12
-
-
0019966111
-
Bronchoconstrictor effects of leukotriene C in humans
-
Weiss JW, Drazen JM, Coles N, McFadden ER Jr, Weller PF, Corey EJ et al. Bronchoconstrictor effects of leukotriene C in humans. Science 1982; 216:196-8.
-
(1982)
Science
, vol.216
, pp. 196-198
-
-
Weiss, J.W.1
Drazen, J.M.2
Coles, N.3
McFadden Jr., E.R.4
Weller, P.F.5
Corey, E.J.6
-
13
-
-
0025647031
-
The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air
-
Israel E, Dermarkarian R, Rosenberg M, Sperling R, Taylor G, Rubin P et al. The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air. N Engl J Med 1990; 323:1740-4.
-
(1990)
N Engl J Med
, vol.323
, pp. 1740-1744
-
-
Israel, E.1
Dermarkarian, R.2
Rosenberg, M.3
Sperling, R.4
Taylor, G.5
Rubin, P.6
-
14
-
-
0027369276
-
The effect of inhibition of 5-lipoxygenase by zileuton in mild to moderate asthma
-
Israel E, Rubin P, Kemp JP, Grossman J, Pierson WE, Siegel SC et al. The effect of inhibition of 5-lipoxygenase by zileuton in mild to moderate asthma. Ann Int Med 1993; 119:1059-66.
-
(1993)
Ann Int Med
, vol.119
, pp. 1059-1066
-
-
Israel, E.1
Rubin, P.2
Kemp, J.P.3
Grossman, J.4
Pierson, W.E.5
Siegel, S.C.6
-
15
-
-
0028103864
-
4 receptor antagonist, in subjects with bronchial asthma
-
4 receptor antagonist, in subjects with bronchial asthma. Am J Respir Crit Care Med 1994; 150:618-23.
-
(1994)
Am J Respir Crit Care Med
, vol.150
, pp. 618-623
-
-
Spector, S.L.1
Smith, L.J.2
Glass, M.3
Birmingham, B.K.4
Bronsky, E.A.5
Dunn, K.D.6
-
16
-
-
0031024694
-
Effects of montelukast (MK-0476), a potent cysteinyl leukotriene receptor antagonist, on bronchodilation in asthmatic subjects treated with and without inhaled corticosteroids
-
Reiss TF, Sorkness CA, Stricker W, Botto A, Busse WW, Kundu S et al. Effects of montelukast (MK-0476), a potent cysteinyl leukotriene receptor antagonist, on bronchodilation in asthmatic subjects treated with and without inhaled corticosteroids. Thorax 1997; 52:45-8.
-
(1997)
Thorax
, vol.52
, pp. 45-48
-
-
Reiss, T.F.1
Sorkness, C.A.2
Stricker, W.3
Botto, A.4
Busse, W.W.5
Kundu, S.6
-
17
-
-
0014219646
-
Prostaglandins: Members of a hormonal system. These physiologically very potent compounds of ubiquitous occurrence are formed from essential fatty acids
-
Bergstrom S. Prostaglandins: members of a hormonal system. These physiologically very potent compounds of ubiquitous occurrence are formed from essential fatty acids. Science 1967; 157:382-91.
-
(1967)
Science
, vol.157
, pp. 382-391
-
-
Bergstrom, S.1
-
19
-
-
0029873358
-
The suppression of 5-Iipoxygenation of arachidonic acid in human polymorphonuclear leucocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E) -eicosatetraenoic acid: Structure-activity relationship and mechanism of action
-
Petrich K, Ludwig P, Kuhn H, Schewe T. The suppression of 5-Iipoxygenation of arachidonic acid in human polymorphonuclear leucocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E) -eicosatetraenoic acid: structure-activity relationship and mechanism of action. Biochem J 1996; 314:911-6.
-
(1996)
Biochem J
, vol.314
, pp. 911-916
-
-
Petrich, K.1
Ludwig, P.2
Kuhn, H.3
Schewe, T.4
-
20
-
-
0025022489
-
Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis
-
Dixon RA, Diehl RE, Opas E, Rands E, Vickers PJ, Evans JF et al. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 1990; 343:282-4.
-
(1990)
Nature
, vol.343
, pp. 282-284
-
-
Dixon, R.A.1
Diehl, R.E.2
Opas, E.3
Rands, E.4
Vickers, P.J.5
Evans, J.F.6
-
21
-
-
0030200939
-
Inhibition of mitogen-activated protein kinase kinase blocks activation and redistribution of 5-lipoxygenase in HL-60 cells
-
Lepley RA, Fitzpatrick FA. Inhibition of mitogen-activated protein kinase kinase blocks activation and redistribution of 5-lipoxygenase in HL-60 cells. Arch Biochem Biophys 1996; 331:141-4.
-
(1996)
Arch Biochem Biophys
, vol.331
, pp. 141-144
-
-
Lepley, R.A.1
Fitzpatrick, F.A.2
-
22
-
-
0028049483
-
Irreversible inactivation of 5-lipoxygenase by leukotriene A4. Characterization of product inactivation with purified enzyme and intact leukocytes
-
Lepley RA, Fitzpatrick FA. Irreversible inactivation of 5-lipoxygenase by leukotriene A4. Characterization of product inactivation with purified enzyme and intact leukocytes. J Biol Chem 1994; 269:2627-31.
-
(1994)
J Biol Chem
, vol.269
, pp. 2627-2631
-
-
Lepley, R.A.1
Fitzpatrick, F.A.2
-
23
-
-
0028323505
-
Granulocyte-macrophage colony-stimulating factor enhances 5-lipoxygenase levels in human polymorphonuclear leukocytes
-
Pouliot M, Mcdonald PP, Khamzina L, Borgeat P, McColl SR. Granulocyte-macrophage colony-stimulating factor enhances 5-lipoxygenase levels in human polymorphonuclear leukocytes. J Immunol 1994; 152:851-8.
-
(1994)
J Immunol
, vol.152
, pp. 851-858
-
-
Pouliot, M.1
Mcdonald, P.P.2
Khamzina, L.3
Borgeat, P.4
McColl, S.R.5
-
24
-
-
0026550008
-
On the expression and regulation of 5-lipoxygenase in human lymphocytes
-
Jakobsson PJ, Steinhilber D, Odlander B, Radmark O, CIaesson HE, Samuelsson B. On the expression and regulation of 5-lipoxygenase in human lymphocytes. Proc Natl Acad Sci USA 1992; 89:3521-5.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 3521-3525
-
-
Jakobsson, P.J.1
Steinhilber, D.2
Odlander, B.3
Radmark, O.4
Ciaesson, H.E.5
Samuelsson, B.6
-
25
-
-
0027201029
-
Serum factors regulate 5-lipoxygenase activity in maturating HL60 cells
-
Steinhilber D, Hoshiko S, Grunewald J, Radmark O, Samuelsson B. Serum factors regulate 5-lipoxygenase activity in maturating HL60 cells. Biochim Biophys Acta 1993; 1178:1-8.
-
(1993)
Biochim Biophys Acta
, vol.1178
, pp. 1-8
-
-
Steinhilber, D.1
Hoshiko, S.2
Grunewald, J.3
Radmark, O.4
Samuelsson, B.5
-
26
-
-
0029068016
-
Granulocyte-macrophage colony-stimulating factor increases 5-lipoxygenase gene transcription and protein expression in human neutrophils
-
Stankova J, Rolapleszczynski M, Dubois CM. Granulocyte-macrophage colony-stimulating factor increases 5-lipoxygenase gene transcription and protein expression in human neutrophils. Blood 1995; 85:3719-26.
-
(1995)
Blood
, vol.85
, pp. 3719-3726
-
-
Stankova, J.1
Rolapleszczynski, M.2
Dubois, C.M.3
-
27
-
-
0031049318
-
Repression of the 5-lipoxygenase gene by c-myb overexpression in differentiated HL-60 cells
-
Ponton A, Thirion JP, Sirois P. Repression of the 5-lipoxygenase gene by c-myb overexpression in differentiated HL-60 cells. Prostaglandins 1997; 53:49-58.
-
(1997)
Prostaglandins
, vol.53
, pp. 49-58
-
-
Ponton, A.1
Thirion, J.P.2
Sirois, P.3
-
29
-
-
0001317441
-
Mechanisms of transcriptional control as revealed by studies of human transcription factor Sp1
-
McKnight SL, Yamamoto KR. (eds) Cold Spring Harbor, NY. Cold Spring Harbor Press
-
Courey AJ, Tjian R. Mechanisms of transcriptional control as revealed by studies of human transcription factor Sp1. In: McKnight SL, Yamamoto KR. (eds) Transcriptional Regulation. Cold Spring Harbor, NY. Cold Spring Harbor Press 1992: 743-769.
-
(1992)
Transcriptional Regulation
, pp. 743-769
-
-
Courey, A.J.1
Tjian, R.2
-
30
-
-
0029996110
-
Egr-1-induced endothelial gene expression: A common theme in vascular injury
-
Khachigian LM, Linder V, Williams AJ, Collins T. Egr-1-induced endothelial gene expression: a common theme in vascular injury. Science 1996; 271:1427-31.
-
(1996)
Science
, vol.271
, pp. 1427-1431
-
-
Khachigian, L.M.1
Linder, V.2
Williams, A.J.3
Collins, T.4
-
31
-
-
33751268215
-
Inducible PDGF α-chain transcription in smooth muscle cells is mediated by Egr-1 displacement of Sp1 and Sp3
-
Silverman ES, Khachigian LM, Lindner V, Williams AJ, Collins T. Inducible PDGF α-chain transcription in smooth muscle cells is mediated by Egr-1 displacement of Sp1 and Sp3. Am J Physiol-Heart Circ Phy 1997; 42:H1415-H1426.
-
(1997)
Am J Physiol-Heart Circ Phy
, vol.42
-
-
Silverman, E.S.1
Khachigian, L.M.2
Lindner, V.3
Williams, A.J.4
Collins, T.5
-
32
-
-
0025913687
-
Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation
-
Kharbanda S, Nakamura T, Stone R, Hass R, Bernstein S, Datta R et al. Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation. J Clin Invest 1991; 88:571-7.
-
(1991)
J Clin Invest
, vol.88
, pp. 571-577
-
-
Kharbanda, S.1
Nakamura, T.2
Stone, R.3
Hass, R.4
Bernstein, S.5
Datta, R.6
-
33
-
-
0028788227
-
Interplay of Sp1 and Egr-1 in the proximal platelet-derived growth factor a-chain promoter in cultured vascular endothelial cells
-
Khachigian LM, Williams AJ, Collins T. Interplay of Sp1 and Egr-1 in the proximal platelet-derived growth factor a-chain promoter in cultured vascular endothelial cells. J Biol Chem 1995; 270:27679-86.
-
(1995)
J Biol Chem
, vol.270
, pp. 27679-27686
-
-
Khachigian, L.M.1
Williams, A.J.2
Collins, T.3
-
34
-
-
0031003816
-
Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription
-
In KH, Asano K, Beier D, Grobholz J, Finn PW, Silverman EK et al. Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription. J Clin Invest 1997; 99:1130-7.
-
(1997)
J Clin Invest
, vol.99
, pp. 1130-1137
-
-
In, K.H.1
Asano, K.2
Beier, D.3
Grobholz, J.4
Finn, P.W.5
Silverman, E.K.6
|