-
2
-
-
0027735897
-
Adenovirus-mediated gene transfer of the CFTR gene to lung of nonhuman primates: A toxicity study
-
R. H. Simon, J. F. Engelhart, Y. Yang, M. Zepeda, S. Weber-Pendelton, M. Grossman, and J. M. Wilson. Adenovirus-mediated gene transfer of the CFTR gene to lung of nonhuman primates: A toxicity study. Hum. Gene Ther. 4:771-780 (1993).
-
(1993)
Hum. Gene Ther.
, vol.4
, pp. 771-780
-
-
Simon, R.H.1
Engelhart, J.F.2
Yang, Y.3
Zepeda, M.4
Weber-Pendelton, S.5
Grossman, M.6
Wilson, J.M.7
-
3
-
-
0029100239
-
A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
-
M. R. Knowles, K. W. Hohneker, Z. Zhou, J. C. Olsen, T. L. Noah, P. C. Hu, M. W. Leigh, J. F. Engelhardt, L. J. Edwards, K. R. Jones, M. Grossman, J. M. Wilson, L. G. Johnson, and R. C. Boucher. A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis. N. Engl. Mal. 333:823-831 (1995).
-
(1995)
N. Engl. Mal.
, vol.333
, pp. 823-831
-
-
Knowles, M.R.1
Hohneker, K.W.2
Zhou, Z.3
Olsen, J.C.4
Noah, T.L.5
Hu, P.C.6
Leigh, M.W.7
Engelhardt, J.F.8
Edwards, L.J.9
Jones, K.R.10
Grossman, M.11
Wilson, J.M.12
Johnson, L.G.13
Boucher, R.C.14
-
4
-
-
0028328261
-
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
-
USA
-
Z. Y. Yang, F. A. Nunes, K. Berencsi, E. E. Furth, E. Gonczol, and J. M. Wilson. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc. Natl. Acad. Sci. USA. 91:4407-4411 (1991).
-
(1991)
Proc. Natl. Acad. Sci.
, vol.91
, pp. 4407-4411
-
-
Yang, Z.Y.1
Nunes, F.A.2
Berencsi, K.3
Furth, E.E.4
Gonczol, E.5
Wilson, J.M.6
-
7
-
-
0027475701
-
Correction of ion transport defect in cystic fibrosis transgenic mice by gene therapy
-
S. C. Hyde, D. R. Gill, C. F. Higgins, A. E. O. Tresize, L. J. Macvinish, A. W. Cuthbert, R. Ratcliff, M. J. Revans, and W. H. Colledge. Correction of ion transport defect in cystic fibrosis transgenic mice by gene therapy. Nature. 362:250-255 (1993).
-
(1993)
Nature
, vol.362
, pp. 250-255
-
-
Hyde, S.C.1
Gill, D.R.2
Higgins, C.F.3
Tresize, A.E.O.4
Macvinish, L.J.5
Cuthbert, A.W.6
Ratcliff, R.7
Revans, M.J.8
Colledge, W.H.9
-
8
-
-
0026459987
-
Aerosol gene delivery in vivo
-
USA
-
G. Stribling, E. Brunette, D. Liggitt, K. Gaensler, and R. Debs. Aerosol gene delivery in vivo. Proc. Natl. Acad. Sci. USA. 89:11277-11281 (1992).
-
(1992)
Proc. Natl. Acad. Sci.
, vol.89
, pp. 11277-11281
-
-
Stribling, G.1
Brunette, E.2
Liggitt, D.3
Gaensler, K.4
Debs, R.5
-
9
-
-
0032080647
-
Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid:cationic lipid complexes
-
B. Freimark, P. Blezinger, V. Florack, J. Nordstrom, S. Long, D. Deshpande, S. Nochumson, and K. Petrak. Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid:cationic lipid complexes. J. Immunol. 160:4580-4586 (1998).
-
(1998)
J. Immunol.
, vol.160
, pp. 4580-4586
-
-
Freimark, B.1
Blezinger, P.2
Florack, V.3
Nordstrom, J.4
Long, S.5
Deshpande, D.6
Nochumson, S.7
Petrak, K.8
-
10
-
-
16944364834
-
Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung
-
R. K. Scheule, et al. Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung. Hum. Gene Ther. 8:689-707 (1997).
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 689-707
-
-
Scheule, R.K.1
-
11
-
-
0030002508
-
Controllable gene therapy. Pharmaceutics of non-viral gene delivery systems
-
E. Tomlinson and R. Rolland. Controllable gene therapy. Pharmaceutics of non-viral gene delivery systems. Journal of Controlled Release. 39:357-372 (1996).
-
(1996)
Journal of Controlled Release
, vol.39
, pp. 357-372
-
-
Tomlinson, E.1
Rolland, R.2
-
12
-
-
0032543524
-
Synthesis and characterization of long chain acyl carnitine esters: Potentially biodegradable cationic lipids for use in gene therapy
-
in press
-
J. Wang, X. Guo, Y. Xu, L. Barron, and F. C. Szoka, Jr. Synthesis and characterization of long chain acyl carnitine esters: Potentially biodegradable cationic lipids for use in gene therapy. J. Med. Chem. (1998). (in press).
-
(1998)
J. Med. Chem.
-
-
Wang, J.1
Guo, X.2
Xu, Y.3
Barron, L.4
Szoka Jr., F.C.5
-
13
-
-
0025861818
-
Detection of specific polymerase chain reaction products by utilizing the 5′ → 3′ exonuclease activity of Thermus aquaticus DNA polymerase
-
P. M. Holland, R. D. Abramson, R. Watson, and D. H. Gelfand. Detection of specific polymerase chain reaction products by utilizing the 5′ → 3′ exonuclease activity of Thermus aquaticus DNA polymerase. Proc. Natl. Acad. Sci. 8:7276-7280 (1991).
-
(1991)
Proc. Natl. Acad. Sci.
, vol.8
, pp. 7276-7280
-
-
Holland, P.M.1
Abramson, R.D.2
Watson, R.3
Gelfand, D.H.4
-
14
-
-
0028834086
-
Oligonucleotide with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization
-
K. J. Livak, J. A. Flood, J. Marmaro, W. Giusti, and K. Deetz. Oligonucleotide with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization. PCR Methods and Applications. 4:357-362 (1995).
-
(1995)
PCR Methods and Applications
, vol.4
, pp. 357-362
-
-
Livak, K.J.1
Flood, J.A.2
Marmaro, J.3
Giusti, W.4
Deetz, K.5
-
16
-
-
0003194270
-
Controllable Gene Therapy Using Non-viral Systems
-
P. L. Feigner, M. J. Heller, P. Lehn, J. Behr, and F. C. Szoka (eds.), ACS Conference Proceedings Series
-
A. Rolland, and E. Tomlinson. Controllable Gene Therapy Using Non-viral Systems. In P. L. Feigner, M. J. Heller, P. Lehn, J. Behr, and F. C. Szoka (eds.), Artificial Self-Assembling Systems for Gene Delivery. ACS Conference Proceedings Series, 1996, pp. 86-100.
-
(1996)
Artificial Self-Assembling Systems for Gene Delivery
, pp. 86-100
-
-
Rolland, A.1
Tomlinson, E.2
-
17
-
-
0030254351
-
Improvements in cationic liposomes for in vivo gene transfer
-
P. L. Feigner. Improvements in cationic liposomes for in vivo gene transfer. Hum. Gene Ther. 7:1791-1793 (1996).
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 1791-1793
-
-
Feigner, P.L.1
-
18
-
-
0029056088
-
Cellular and molecular barriers to gene transfer by a cationic lipid
-
J. Zabner, A. J. Fasbender, T. Moninger, K. A. Poellinger, and M. J. Welsh. Cellular and molecular barriers to gene transfer by a cationic lipid. J. Biol. Chem. 270:18997-19007 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18997-19007
-
-
Zabner, J.1
Fasbender, A.J.2
Moninger, T.3
Poellinger, K.A.4
Welsh, M.J.5
-
19
-
-
0031104992
-
Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer
-
A. Kichler, K. Mechtler, J. P. Behr, and E. Wagner. Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer. Bioconjugate Chem. 8:213-221 (1997).
-
(1997)
Bioconjugate Chem.
, vol.8
, pp. 213-221
-
-
Kichler, A.1
Mechtler, K.2
Behr, J.P.3
Wagner, E.4
-
20
-
-
15644368435
-
Nucleic acid structures and manipulation
-
John Wiley & Sons, New York, N.Y.
-
D. Voet and J. Voet. Nucleic acid structures and manipulation. In Biochemistry. John Wiley & Sons, New York, N.Y., 1990, pp. 791-851.
-
(1990)
Biochemistry
, pp. 791-851
-
-
Voet, D.1
Voet, J.2
-
21
-
-
0029078436
-
Cholesterol enhances cationic liposome-mediated DNA transfection of human respiratory epithelial cells
-
M. J. Bennett, M. H. Nantz, R. P. Balasubramanium, D. C. Gruenert, and R. W. Malone. Cholesterol enhances cationic liposome-mediated DNA transfection of human respiratory epithelial cells. Bioscience Reports. 15:47-52 (1995).
-
(1995)
Bioscience Reports
, vol.15
, pp. 47-52
-
-
Bennett, M.J.1
Nantz, M.H.2
Balasubramanium, R.P.3
Gruenert, D.C.4
Malone, R.W.5
-
22
-
-
0030794696
-
Effect of co-lipids in enhancing cationic lipid-mediated gene transfer in vitro and in vivo
-
A. Fasbender, J. Marshall, T. O. Moninger, T. Grunst, S. Cheng, and M. J. Welsh. Effect of co-lipids in enhancing cationic lipid-mediated gene transfer in vitro and in vivo. GeneTherapy, 4:716-725 (1997).
-
(1997)
GeneTherapy
, vol.4
, pp. 716-725
-
-
Fasbender, A.1
Marshall, J.2
Moninger, T.O.3
Grunst, T.4
Cheng, S.5
Welsh, M.J.6
-
23
-
-
0030754344
-
Optimization of formulations and conditions for the aerosol delivery of functional cationic lipid:DNA complexes
-
S. J. Eastman, J. D. Tousignant, M. Lukason, H. Murray, C. S. Siegel, P. Constantino, D. J. Harris, S. H. Cheng, and R. K. Scheule. Optimization of formulations and conditions for the aerosol delivery of functional cationic lipid:DNA complexes. Hum. Gene Ther. 8:313-322 (1997).
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 313-322
-
-
Eastman, S.J.1
Tousignant, J.D.2
Lukason, M.3
Murray, H.4
Siegel, C.S.5
Constantino, P.6
Harris, D.J.7
Cheng, S.H.8
Scheule, R.K.9
-
24
-
-
16944361840
-
A concentrated and stable aerosol formulation of cationic lipid:DNA complexes giving high-level gene expression in mouse lung
-
S. J. Eastman, M. Lukason, J. D. Tousignant, H. Murray, M. D. Lane, J. St. George, G. Y. Akita, M. Cherry, S. H. Cheng, and R. Scheule. A concentrated and stable aerosol formulation of cationic lipid:DNA complexes giving high-level gene expression in mouse lung. Hum. Gene Ther. 8:765-773 (1997).
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 765-773
-
-
Eastman, S.J.1
Lukason, M.2
Tousignant, J.D.3
Murray, H.4
Lane, M.D.5
St. George, J.6
Akita, G.Y.7
Cherry, M.8
Cheng, S.H.9
Scheule, R.10
|