BIMA(APC3), component of the Aspergillus anaphase promoting complex/cyclosome, is required for a G2 checkpoint blocking entry into mitosis in the absence of NIMA function

Journal of Cell Science

Volumn 111, Issue 10, 1998, Pages 1453-1465

  Lies, C Mark ^a   Cheng, Jijun ^a   James, Steven W ^b   Morris, N Ronald ^c   O'Connell, Matthew J ^d,e   Mirabito, P M ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b GETTYSBURG COLLEGE   (United States)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^d PETER MACCALLUM CANCER CENTRE   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

APC; Checkpoint; Cyclosome; NIMA

Indexed keywords

CYCLIN B;

ANAPHASE; ARTICLE; ASPERGILLUS NIDULANS; CELL CYCLE G2 PHASE; FUNGUS MUTANT; INTERPHASE; MICROTUBULE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; TEMPERATURE SENSITIVE MUTANT;

ASPERGILLUS; ASPERGILLUS NIDULANS; ASTER; EMERICELLA NIDULANS; FUNGI;

EID: 0031780899     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (58)

1. Cohen-Fix, O., Peters, J. M., Kirschner, M. W. and Koshland, D. (1996). Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds 1p. Genes Dev. 10, 3081-3093.
2. Engle, D. B., Osmani, S. A., Osmani, A. H., Rosborough, S., Xiang, X. and Morris, N. R. (1990). A negative regulator of mitosis in Aspergillus is a putative membrane-spanning protein J. Biol. Chem. 265, 16132-16137.
3. Fry, A. M. and Nigg, E. A. (1995). Cell cycle The NIMA kinase joins forces with Cdc2. Curr. Biol. 5, 1122-1125.
4. Funabiki, H., Yamano, H., Nagao, K., Tanaka, H., Yasuda, H., Hunt, T. and Yanagida, M. (1997). Fission yeast Cut2 required for anaphase has two destruction boxes. EMBO J. 16, 5977-5987.
5. Gwynne, D. I., Buxton, F. P., Sibley, S., Davies, R. W., Lockington, R. A., Scazzocchio, C. and Sealy-Lewis, H. M. (1987) Comparison of the cisacting control regions of two coordinately controlled genes involved in ethanol utilization in Aspergillus nidulans. Gene 51, 205-216.
6. Harlow, E. and Lane, D. (1988). Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press. Cold Spring Harbor. NY.
7. Harris, S. D. and Hamer, J. E. (1995). sepB: an Aspergillus nidulans gene involved in chromosome segregation and the initiation of cytokinesis. EMBO J. 14, 5244-5257.
8. Hershko, A., Ganoth, D., Sudakin, V., Dahan, A., Cohen, L. H., Luca, F. C., Ruderman, J. V. and Eytan, E. (1994). Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2. J. Biol. Chem. 269, 4940-4946.
9. 2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase J. Cell Biol. 106, 1171-1183.
10. Irniger, S., Piatti, S., Michaelis, C. and Nasmyth, K. (1995) Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell 81, 269-277.
11. 1 arrested yeast cells to inhibit B-type cyclin accumulation and to prevent uncontrolled entry into S-phase. J. Cell Sci. 110, 1523-1531.
12. James, S. W., Mirabito, P. M., Scacheri, P. C. and Morris, N. R. (1995) The Aspergillus nidulans bimE (blocked-in-mitosis) gene encodes multiple cell cycle functions involved in mitotic checkpoint control and mitosis. J. Cell Sci. 108, 3485-3499.
13. Juang, Y. L., Huang, J., Peters, J. M., McLaughlin, M. E., Tai, C. Y. and Pellman, D. (1997). APC-mediated proteolysis of Asel and the morphogenesis of the mitotic spindle. Science 275, 1311-1314.
14. Kafer, E. (1977). Meiotic and mitotic recombination in Aspergillus nidulans and its chromosomal aberrations. Advan. Genet. 19, 33-131.
15. King, R. W., Peters, J. M., Tugendreich, S., Rolfe, M., Hieter, P. and Kirschner, M. W. (1995). A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81, 279-288.
16. King, R. W., Deshaies, R. J., Peters, J. M. and Kirschner, M. W. (1996) How proteolysis drives the cell cycle. Science 274, 1652-1659.
17. Kirk, K. E. and Morris, N. R. (1993). Either α-tubulin isogene product is sufficient for microtubule function during all stages of growth and differentiation in Aspergillus nidulans. Mol. Cell Biol. 13. 4465-4476.
18. Koerner, T. J., Hill, J. E., Myers, A. M. and Tzagoloff, A. (1991) High Expression vectors with multiple cloning sites for construction of trpE fusion genes: pATH vectors. Meth. Enzymol. 194, 477-490.
19. 1-arrest upon nitrogen starvation and is an inhibitor of septum formation. J. Cell Sci. 108, 895-905.
20. Lu, K. P., Osmani, S. A. and Means, A. R. (1993). Properties and regulation of the cell cycle-specific NimA protein kinase of Aspergillus nidulans. J. Biol. Chem. 268, 8769-8776.
21. 1 arrest in Aspergillus nidulans. EMBO J. 13, 2103-2113.
22. Lu, K. P. and Hunter, T. (1995). Evidence for a NIMA-like mitotic pathway in vertebrate cells. Cell 81, 413-424.
23. Mirabito, P. M. and Morris, N. R. (1993) BIMA. a TPR-containmg protein required for mitosis, localizes to the spindle pole body in Aspergillus nidulans. J. Cell Biol. 120, 959-968.
24. Morris, N. R. (1976). Mitotic mutants of Aspergillus nidulans. Genet. Res. 26, 237-254.
25. Tude23 in Aspergillus nidulans. EMBO J. 11, 2139-2149.
26. O'Connell, M. J., Norbury, C. and Nurse, P. (1994). Premature chromatin condensation upon accumulation of NIMA. EMBO J. 13, 4926-4937.
27. O'Donnell, K. L., Osmani, A. H., Osmani, S. A. and Morris, N. R. (1991) bimA encodes a member of the tetratricopeptide repeal family of proteins and is required for the completion of mitosis in Aspergillus nidulans. J. Cell Sci. 99, 711-719.
28. Oakley, B. R. and Morris, N. R. (1981). A beta tubulin mutation in Aspergillus nidulans that blocks microtubule function without blocking assembly. Cell 24, 837-845.
29. 2-M transition in Aspergillus nidulans. J. Cell Biol. 104 1495-1504.
30. Osmani, S. A., Engle, D. B., Doonan, J. H. and Morris, N. R. (1988). Spindle formation and chromatin condensation in cells blocked at interphase by mutation of a negative cell cycle control gene. Cell 52, 241-251.
31. cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans. Cell 67, 283-291.
32. Osmani, A. H., O'Donnell, K., Pu, R. T. and Osmani, S. A. (1991b). Activation of the nimA protein kinase plays a unique role during mitosis that cannot be bypassed by absence of the bimE checkpoint. EMBO J. 10, 2669-2679.
33. Osmani, S. A. and Ye, X. S. (1996). Cell cycle regulation in Aspergillus by two protein Kinases. Biochem. J. 317, 633-641.
34. Pellman, D., Bagget, M., Tu, Y. H., Fink, G. R. and Tu, H. T. (1995). Two microtubule-associated proteins required for anaphase spindle movement in Saccharomyces cerevisiae. J. Cell. Biol. 130, 1373-1385.
35. Peters, J.-M., King, R. W., Hoog, C. and Kirschner, M. W. (1996) Identification of BIME as a subunit of the anaphase-promoting complex. Science 274, 1199-1201.
36. Pontecorvo, G., Koper, J. A., Hemmons, K. M., MacDonald, K. D. and Buffon, A. W. J. (1953). The genetics of Aspergillus nidulans. Advan. Genet. 5, 141-238.
37. Pu, R. T. and Osmani, S. A. (1995). Mitotic destruction of the cell cycle regulated NIMA protein kinase of Aspergillus nidulans is required for mitotic exit. EMBO J. 14, 995-1003.
38. Rio, D. C., Laski, F. A. and Rubin, G. M. (1986). Identification and immunochemical analysis of biologically active Drosophila P element transposase. Cell 44, 21-32.
39. Ruther, U. and Muller-Hill, B. (1983). Easy identification of cDNA clones. EMBO J. 2, 1791-1794.
40. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
41. + to initiate anaphase. J. Cell Biol. 127, 1655-1670.
42. Starborg, M., Brundell, E., Cell, K. and Hoog, C. (1994). A novel murine gene encoding a 216-kDa protein is related to a mitotic checkpoint regulator previously identified in Aspergillus nidulans. J. Biol. Chem. 269, 24133-24137.
43. Surana, U., Amon, A., Dowzer, C., McGrew, J., Byers, B. and Nasmyth, K. (1995). Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. EMBO J. 12, 1969-1978.
44. Tugendreich, S., Tomkiel, J., Earnshaw, W. and Hieter, P. (1995). CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition. Cell 81, 261-268.
45. Upshall, A. and Mortimore, I. D. (1984). Isolation of aneuploid-generating mutants of Aspergillus nidulans. one of which is defective in interphase of the cell cycle. Genetics 108, 107-121.
46. Waring, R. B., May, G. S. and Morris, N. R. (1989). Characterization of an inducible expression system in Aspergillus nidulans using alcA and tubulincoding genes. Gene 79, 119-130.
47. Yamada, H., Kumada, K. and Yanagida, M. (1997). Distinct subunit functions and cell cycle regulated phosphorylation of the 20S APC/Cyclosome required for anaphase in fission yeast. J. Cell Sci. 110, 1793-1804.
48. Yamamoto, A., Guacci, V. and Koshland, U. (1996a). Pdslp is required for faithful execution ot anaphase in yeast. Saccharomyces cerevistae. J. Cell Biol. 133, 85-97.
49. Yamamoto, A., Guacci, V. and Koshland, D. (1996b). Pdslp. an inhibitor of anaphase in budding yeast plays a critical role in the APC and checkpoint pathways. J. Cell Biol. 133, 99-110.
50. Yamashita, Y. M., Nakaseko, Y., Samejima, I., Kumada, K., Yamada, H., Michaelson, D. and Yanagida, M. (1996). 20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway. Nature 384, 276-279.
51. cdc2/Cyclin B: Coordination of two mitosis promoting kinases. EMBO J. 14, 986-994.
52. Ye, X. S., Fincher, R. R., Tang, A., O'Donnell, K. and Osmani, S. A. (1996). Two S-phase checkpoint systems, one involving the function of both BIME and Tyt15 phosphorylation of p34cdc2, inhibit NIMA and prevent premature mitosis. EMBO J. 15, 3599-3610.
53. Ye, X. S., Xu, G., Fincher, R. R. and Osmani, S. A. (1997a) Characterization of NIMA protein kinase in Aspergillus nidulans. Meth. Enzymol. 283, 520-532.
54. cdc2. J. Biol. Chem. 272, 33384-33393.
55. Yu, H., Peters, J.-M., King, R. W., Page, A. M., Hieter, P. and Kirschner, M. W. (1998). Identification of a Cullin homology in a subunit of the anaphase-promoting complex. Science 279, 1219-1222.
56. Zachariae, W. and Nasmyth, K. (1996a). TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast. Mol. Biol. Cell 7, 791-801.
57. Zachariae, W., Shin, T. H., Galova, M., Obermaier, B. and Nasmyth, K. (1996b). Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae. Science 274, 1201-1204.
58. Zachariae, W., Shevchenko, A., Andrews, P. D., Ciosk, R., Galova, M., Stark, M. J. R., Mann, M. and Nasmyth, K. (1998). Mass spectrometric analysis of the anaphase-promoting complex from yeast: Identification of a subunit related to Cullins. Science 279, 1216-1219.