Important drug-nutrient interactions in the elderly

Drugs and Aging

Volumn 13, Issue 3, 1998, Pages 199-209

  Thomas, John A ^a   Burns, Robert A ^b  

^a University of Texas Health Science Center   (United States)

^b Mead Johnson Nutritionals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; ANTACID AGENT; ANTIBIOTIC AGENT; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; ANTIINFLAMMATORY AGENT; ANTILIPEMIC AGENT; CALCIUM ANTAGONIST; COLESTYRAMINE; CYTOTOXIC AGENT; DIGOXIN; DIURETIC AGENT; FOSCARNET; LAXATIVE; PRAVASTATIN; SULFONYLUREA; TETRAHYDROLIPSTATIN; UNINDEXED DRUG; WARFARIN;

AGED; AGING; APPETITE; BLEEDING; CONGESTIVE HEART FAILURE; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; FOOD DRUG INTERACTION; HEART FUNCTION; HUMAN; INTESTINE ABSORPTION; NAUSEA; OBESITY; OSTEOPOROSIS; PRIORITY JOURNAL; REVIEW; URINARY EXCRETION; VOMITING;

AGED; AGING; FOOD-DRUG INTERACTIONS; HUMANS; NUTRITIONAL STATUS; PHARMACOKINETICS;

EID: 0031709116     PISSN: 1170229X     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002512-199813030-00003     Document Type: Review

References (60)

1. Stein BE. Avoiding drug reactions: seven steps to writing safe prescriptions. Geriatrics 1984; 49 (9): 28-36
2. Ahronheim J. Practical pharmacology for older patients: avoiding adverse drug effects. Mt Sinai J Med 1993; 60 (6): 497-501
3. Johnson JC. General concepts of geriatric medicine. Clin Podiatr Med Surg 1993; 10 (1): 23-33
4. Roe DA. Medications and nutrition in the elderly. Prim Care 1994; 21 (1): 135-47
5. Aparasu RR, Fliginger SB. Inappropriate medication prescribing for the elderly hy office-based physicians. Ann Pharmacother 1997; 31: 823-9
6. Carlson JE. Perils of polypharmacy: 10 steps to prudent prescribing. Geriatrics 1996; 51 (7): 26-35
7. Chen LH, Liu S, Cook Newell ME, et al. Survey of drug use by the elderly and possible impact of drugs on nutritional status. Drug Nutr Interact 1985; 3: 73-86
8. Munro HN, Suter PM, Russell RM. Nutritional requirements of the elderly. Annu Rev Nutr 1987; 7: 23-49
9. Smith CH. Drug-food/food-drug interactions. In: Morley JE, Glick Z, Rubenstein LZ, editors. Geriatric nutrition: a comprehensive review. New York: Raven Press, 1990: 371-396
10. Yamreudeewong W, Henann NE, Fazio A, et al. Drug-food interactions in clinical practice. J Fam Pract 1995; 40 (4): 376-84
11. Kirk JK. Significant drug-nutrient interactions. Am Fam Physician 1995; 51 (5): 1175-82
12. Randle NW. Food or nutrient effects on drug absorption: a review. Hosp Pharm 1987; 22: 694-697, 718
13. Smith CH, Bidlack WR. Dietary concerns associated with the use of medications. J Am Diet Assoc 1984; 84: 901-14
14. Garabedian-Ruffalo SM, Syria-Harber M, Lanius PM, et al. Monitoring of drug-drug and drug-food interactions. Am J Hosp Pharm 1988; 45: 1530-4
15. Thomas JA. Drug-nutrient interactions. Nutr Rev 1995; 53: 271-82
16. Thomas JA, Tschanz C. Nutrient-drug interactions. In: Kotsonis FN, Mackey M, Hjelle JJ, editors. Nutritional toxicology, target organ toxicity series. New York: Raven Press, 1994: 134-48
17. Hurwitz A, Brady DA, Schaal SE et al. Gastric acidity in older adults. JAMA 1997; 278 (8): 659-82
18. De Ponti F, Giaroni C, Cosentino M, et al. Adrenergic mechanisms in the control of gastrointestinal mortility: from basic science to clinical applications. Pharmacol Ther 1996; 69: 59-78
19. Tsuji A, Tamai I. Carrier-mediated intestinal transport of drugs. Pharm Res 1996; 13 (7): 963-77
20. Mizuma T, Sakai N, Awazu S. Na+-dependent transport of aminopeptidase-resistant sugar-coupled tripeptides in rat intestine. Biochem Biophys Res Commun 1994; 203: 1412-6
21. Simanjuntak MT, Tamai I, Terasaki T, et al. Carrier-mediated uptake of nicotinic acid by rat intestinal brush-border membrane vesicles and relation to monocarboxylic acid transport. J Pharmacobiodyn 1990; 13: 301-9
22. Welling PG. Effects of food on drug absorption. Annu Rev Nutr 1996; 16: 383-415
23. Hoyumpa AM, Schenker S. Major drug interactions: effect of liver disease, alcohol, and malnutrition. Annu Rev Med 1982; 33: 113-49
24. Trovato A, Nuhlicek DN, Midtling JE. Drug-nutrient interactions. Am Fam Physician 1991; 44 (5): 1651-8
25. Hammerlein A, Derendorf H, Lowenthal DT. Pharmacokinetic and pharmacodynamic changes in the elderly. Clin Pharmacokinet 1998; 35 (1): 49-64
26. Michalets E. Update: clinically significant cytochrome P-450 drug interactions. Pharmacotherapy 1998; 18: 84-112
27. Steffens DC, Ranga Rama Krishnan K. Metabolism, bioavailability and drug interactions. Clin Geriatr Med 1998; 14 (1): 17-31
28. Bennett WM, Porter GA. Overview of clinical nephrotoxicity. In: Hook JB, Goldstein RS, editors. Toxicology of the kidney: target organ toxicity series. 2nd ed. New York: Raven Press, 1993: 61-97
29. Roe DA. Drug and food interactions as they affect the nutrition of older individuals. Aging Clin Exp Res 1993; 5 (2 Suppl. 1): 51-3
30. Roe DA. Therapeutic significance of drug-nutrient interactions in the elderly. Pharmacol Rev 1984; 36 (2 Suppl.): 109S-22S
31. Cardinale V. Stemming the tide of polymedicine. Drug Topics 1988; 132: 36-41
32. Lamy PP. Effects of diet and nutrition on drug therapy. J Am Geriatric Soc 1982; 30 (11 Suppl.): S99-S112
33. Moorandian AD. Nutritional modulation of life span and gene expression. Ann Intern Med 1988; 109: 891-2
34. Nordin B. Calcium and Osteoporosis. Nutrition 1997; 13: 664-86
35. Guttman P. Patterns of legal drug use by older Americans. Addict Dis 1978; 3: 337-56
36. Ouslander JG. Drug therapy and the elderly. Ann Intern Med 1981; 95: 711-22
37. Roe DA. Drug and nutrient interactions in the elderly diabetic. Drug Nutr Interact 1988; 5: 195-203
38. Susman JL, Helseth LD. Reducing the complications of type II diabetes: a patient-centered approach. Am Fam Physician 1997; 56: 471-8
39. King H, Rewers M. World Health Organisation Diabetes Reporting Group. Global estimates for prevalence of diabetes mellitus and impaired glucose tolerance in adults. Diabetes Care 1993; (16): 157-77
40. Roe DA. Interactions between drugs and nutrients. Med Clin North Am 1979; 63: 985-1007
41. Tschanz C, Stargel WW, Thomas JA. Interactions between drugs and nutrients. Adv Pharmacol 1996; 35: 1-26
42. Spencer CM, Markham A. Troglitazone. Drugs 1997; 54 (1): 89-101
43. Shibata H, Kobayashi NS, et al. Phase I study of a new hypoglycemic agent CS-045 in healthy volunteers: safety and pharmacokinetics in single administration [in Japanese]. Rinsho Iyaku 1993; 9 (7): 1503-8
44. Stiefeld SM, Graziani AL, MacGregor RR, et al. Toxicities of antimicrobial agents used to treat osteomyelitis. Orthop Clin North Am 1991; 22: 439-65
45. Hulin B. New hypoglycemic agents. Prog Med Chem 1994; 31: 1-58
46. Roe DA. Drug and nutrient interactions in elderly cardiac patients. Drug Nutr Interact 1988; 5: 205-12
47. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997; 65 Suppl. 2: 678S-81S
48. Diaz MN, Frei B, Vita JA, et al. Antioxidants and atherosclerotic heart disease. N Engl J Med 1997; 337 (6): 408-16
49. Lee M, Schwartz RN, Sharifi R. Warfarin resistance and vitamin K. Arch Intem Med 1981; 94: 140-1
50. Wells PS, Holbrook AM, Crowther NR, et al. Interactions of warfarin with drugs and food. Ann Intern Med 1994; 121: 676-83
51. Harris JE. Interaction of dietary factors with oral anticoagulants: review and applications. J Am Diet Assoc 1995; 95 (5): 580-4
52. Fujimura A, Shiga T, Kumagai Y, et al. Effect of food intake on pharmacokinetics and effects of a new thromboxane A2 receptor antagonist. Euro J Clin Pharmacol 1996; 50 (4): 311-4
53. Nordin BEC. Calcium and osteoporosis. Nutrition 1997; 13(7/8): 664-86
54. Bronner F. Intestinal calcium absorption: mechanisms and applications. J Nutr 1987; 11: 1347-1352
55. D'Arcs PF, McElnay JC. Drug interactions in the gut involving metal ions. Rev Drug Metabol Drug Interact 1985; 5: 83-99
56. Perlia CP, Gubisch NJ, Wolter J, et al. Mithramycin treatment of hypercalcemia. Cancer 1970; 25: 389-94
57. Guillaume M, Björntorp P. Obesity in children: environmental and genetic aspects. Horm Metab Res 1996; 28: 573-81
58. Rosenbaum M, Leibel RL, Hirsch J. Obesity. N Engl J Med 1997; 337 (6): 396-407
59. Guerciolini R. Mode of action of orlistat. Int J Obes 1997; 21 Suppl. 3: S12-23
60. Goldman P. Olestra: assessing its potential to interact with drugs in the gastrointestinal tract. J Clin Pharm Ther 1997; 61: 613-8