Radiation-activated prodrugs as hypoxia-selective cytotoxins: Model studies with nitroarylmethyl quaternary salts

Anti-Cancer Drug Design

Volumn 13, Issue 6, 1998, Pages 663-685

  Wilson, William R ^a   Tercel, Moana ^a   Anderson, Robert F ^a   Denny, William A ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Hypoxia; Ionizing radiation; Nitroarylmethyl quaternary salts; Prodrugs

Indexed keywords

ANTINEOPLASTIC AGENT; NITROARYLMETHYL QUATERNARY SALT; OXIDOREDUCTASE; OXYGEN; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVATION; DRUG DESIGN; ELECTRON; HYPOXIA; IONIZING RADIATION; MOUSE; NONHUMAN; PLASMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION; REDUCTION; REVIEW;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL HYPOXIA; HUMANS; METHYLATION; NITRO COMPOUNDS; OXIDATION-REDUCTION; OXIDOREDUCTASES; PRODRUGS; RADIATION, IONIZING;

EID: 0031706557     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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