Doublefoot: A new mouse mutant affecting development of limbs and head

Genetical Research

Volumn 68, Issue 3, 1996, Pages 221-231

  Lyon, Mary F ^a   Quinney, R ^a   Glenister, P H ^a   Kerscher, S ^a,b   Guillot, P ^a   Boyd, Y ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CHROMOSOME 1; CONTROLLED STUDY; CROSSING OVER; DEVELOPMENTAL GENETICS; EDEMA; EMBRYO; EMBRYO DEVELOPMENT; ESTRUS CYCLE; FACE MALFORMATION; FEMALE; FIBULA; FOOT SOLE; GENE MAPPING; GROWTH RETARDATION; HEAD; HETEROZYGOTE; HYDROCEPHALUS; LIMB DEVELOPMENT; MALE; MALE FERTILITY; MAXILLA; MOUSE; MOUSE MUTANT; NONHUMAN; PHENOTYPE; POLYDACTYLY; REPRODUCTION; SPERMATOZOON COUNT; TAIL; TESTIS WEIGHT; TIBIA; VAGINA;

ANIMALIA; SOLEIDAE;

EID: 0030498386     PISSN: 00166723     EISSN: None     Source Type: Journal    
DOI: 10.1017/s0016672300034194     Document Type: Article

References (30)

1. Charité, J., DeGraaff, W., Shen, S. & Deschamps, J. (1994). Ectopic expression of Hoxb-8 causes duplication of the ZPA in the forelimb and homeotic transformation of axial structures. Cell 78, 589-601.
2. Cohn, M. J. & Tickle, C. (1996). Limbs: a model for pattern formation within the vertebrate body plan. Trends Genet. 12, 253-257.
3. Colvin, J. S., Bohne, B. A., Harding, G. W., McEwen, D. G. & Ornitz, D. M. (1996). Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nature Genetics 12, 390-397.
4. Deng, C., Wynshaw-Boris, A., Zhou, F., Kuo, A. & Leder, P. (1996). Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell 84, 911-921.
5. 2H) a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3. Cell 67, 767-774.
6. 4H deletion may contain a new locus essential for postimplantation development. Genomics 34, 205-212.
7. 3) limb buds: their relationships in the signalling cascade involved in limb patterning. Developmental Dynamics 203, 187-197.
8. Goulding, M. D., Chalepakis, G., Deutsch, U., Erselius, J. R. & Gruss, P. (1991). Pax-3, a novel murine DNA binding protein expressed during early neurogenesis. EMBO Journal 10, 1135-1147.
9. Higgins, M., Hill, R. E. & West, J. D. (1992). Dominant hemimelia and En-1 on mouse chromosome 1 are not allelic. Genetical Research 60, 53-60.
10. Hogan, B., Costantini, F. & Lacy, E. (1986). Manipulating the Mouse Embryo: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
11. Hoth, C. F., Milunsky, A., Lipsky, N., Sheffer, R., Clarren, C. K. & Baldwin, C. T. (1993). Mutations in the paired domain of the human PAX3 gene cause Klein-Waardenburg syndrome (WSIII) as well as Waardenburg syndrome type I (WSI). American Journal of Human Genetics 52, 455-62.
12. Johnson, R. L., Riddle, R. D. & Tabin, C. J. (1994). Mechanisms of limb patterning. Current Opinion in Genetics and Development 4, 535-542.
13. Laufer, E., Nelson, C. E., Johnson, R. L., Morgan, B. A. & Tabin, C. (1994). Sonic hedgehog and Fgf-4 act through a signalling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003.
14. Lyon, M. F., Quinney, R. & Whitehill, K. (1989). Doublefoot, a new mutation affecting limb development. Mouse News Letter 83, 158.
15. Lyon, M. F., Cocking, Y. & Gao, X. (1996). Mouse chromosome atlas. Mouse Genome 94, 29-73.
16. Mahmood, R., Bresnick, J., Hornbruch, A., Mahony, C., Morton, N., Colquhoun, K., Martin, P., Lumsden, A., Dickson, C. & Mason, I. (1995). A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth. Current Biology 5, 797-806.
17. Masuya, H., Sagai, T., Wakana, S., Moriwaki, K. & Shiroishi, T. (1995). A duplicated zone of polarizing activity in polydactylous mouse mutants. Genes & Development 9, 1645-1653.
18. Miller, J. C., et al. (1996). SSLP/Microsatellite genetic linkage map of the mouse. In Genetic Variants and Strains of the Laboratory Mouse, 3rd edn (ed. M. F. Lyon, S. Rastan & S. D. M. Brown), pp. 1671-1755. Oxford: Oxford University Press.
19. Niswander, N., Jeffley, S., Martin, G. R. & Tickle, C. (1994). A positive feedback loop coordinates growth and patterning in the developing limb. Nature 371, 609-612.
20. Parr, B. A. & McMahon, A. P. (1995). Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature 374, 350-353.
21. Riddle, R. D., Johnson, R. L., Laufer, E. & Tabin, C. (1993). Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416.
22. Savage, M. P., Hart, C. E., Riley, B. B., Sasse, J., Olwin, B. B. & Falleon, J. F. (1993). Distribution of FGF-2 suggests it has a role in chick limb bud growth. Developmental Dynamics 198, 159-170.
23. Searle, A. G. (1964). The genetics and morphology of two luxoid mutants in the house mouse. Genetical Research 5, 171-197.
24. Searle, A. G. & Beechey, C. V. (1974). Sperm-count, egg-fertilization and dominant lethality after X-irradiation of mice. Mutation Research 22, 63-72.
25. Sheffer, R. & Zlotogora, J. (1992). Autosomal dominant inheritance of Klein-Waardenberg syndrome. American Journal of Medical Genetics 42, 320-322.
26. Tassabheji, M., Read, A. P., Newton, V. E., Patton, M., Gruss, P., et al. (1993). Mutations in the PAX3 gene causing Waardenburg syndrome type 1 and type 2. Nature Genetics 3, 26-30.
27. Tickle, C. (1995). Vertebrate limb development. Current Opinion in Genetics and Development 5, 478-484.
28. Vortkamp, A., Franz, T., Gessler, M. & Grzeschik, K.-H. (1992). Deletion of GLI3 supports the homology of the human Greig cephalopolysyndactly syndrome (GCPS) and the mouse mutant extra toes (Xt). Mammalian Genome 3, 461-463.
29. Yamaguchi, T. P. & Rossant, J. (1995). Fibroblast growth factors in mammalian development. Current Opinion in Genetics and Development 5, 485-491.
30. Yang, Y. & Niswander, L. (1995). Interaction between the signalling molecules WNT7a and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning. Cell 80, 939-947.