메뉴 건너뛰기




Volumn 28, Issue 10, 1998, Pages 2991-3002

Transient alteration of T cell fine specificity by a strong primary stimulus correlates with T cell receptor down-regulation

Author keywords

Altered peptide ligand; LCMV; Serial triggering; TCR down regulation; TCR transgenic mouse

Indexed keywords

T LYMPHOCYTE RECEPTOR;

EID: 0031688113     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199810)28:10<2991::AID-IMMU2991>3.0.CO;2-B     Document Type: Article
Times cited : (24)

References (55)
  • 2
    • 0028988331 scopus 로고
    • T cell receptor antagonists and partial agonists
    • Jameson, S. C. and Bevan, M. J., T cell receptor antagonists and partial agonists. Immunity 1995. 2: 1-11.
    • (1995) Immunity , vol.2 , pp. 1-11
    • Jameson, S.C.1    Bevan, M.J.2
  • 3
    • 0029933309 scopus 로고    scopus 로고
    • Altered peptide ligand-induced partial T cell activation: Molecular mechanisms and role in T cell biology
    • Sloan-Lancaster, J. and Allen, P. M., Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. Annu. Rev. Immunol. 1996. 14: 1-27.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 1-27
    • Sloan-Lancaster, J.1    Allen, P.M.2
  • 5
    • 0028360076 scopus 로고
    • Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells
    • Bertoletti, A., Sette, A., Chisari, F. V., Penna, A., Levrero, M., De Carli, M., Fiaccadori, F. and Ferrari, C., Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells. Nature 1994. 369: 407-410.
    • (1994) Nature , vol.369 , pp. 407-410
    • Bertoletti, A.1    Sette, A.2    Chisari, F.V.3    Penna, A.4    Levrero, M.5    De Carli, M.6    Fiaccadori, F.7    Ferrari, C.8
  • 12
    • 0028123067 scopus 로고
    • Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 NEF protein
    • Couillin, I., Culmann-Penciolelli, B., Gomard, E., Choppin, J., Levy, J.-P., Guillet, J.-G. and Saragosti, S., Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 NEF protein. J. Exp. Med. 1994. 180: 1129-1134.
    • (1994) J. Exp. Med. , vol.180 , pp. 1129-1134
    • Couillin, I.1    Culmann-Penciolelli, B.2    Gomard, E.3    Choppin, J.4    Levy, J.-P.5    Guillet, J.-G.6    Saragosti, S.7
  • 13
    • 0028086591 scopus 로고
    • Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope
    • Bertoletti, A., Costanzo, A., Chisari, F. V., Levrero, M., Artini, M., Sette, A., Penna, A., Giuberti, T., Fiaccadori, F. and Ferrari, C., Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope. J. Exp. Med. 1994. 180: 933-943.
    • (1994) J. Exp. Med. , vol.180 , pp. 933-943
    • Bertoletti, A.1    Costanzo, A.2    Chisari, F.V.3    Levrero, M.4    Artini, M.5    Sette, A.6    Penna, A.7    Giuberti, T.8    Fiaccadori, F.9    Ferrari, C.10
  • 14
    • 0030249395 scopus 로고    scopus 로고
    • Cytotoxic T cell-resistant variants are selected in a virus-induced demyelinating disease
    • Pewe, L., Wu, G. F., Barnett, E. M., Castro, R. F. and Perlman, S., Cytotoxic T cell-resistant variants are selected in a virus-induced demyelinating disease. Immunity 1996. 5: 253-262.
    • (1996) Immunity , vol.5 , pp. 253-262
    • Pewe, L.1    Wu, G.F.2    Barnett, E.M.3    Castro, R.F.4    Perlman, S.5
  • 15
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • Pircher, H., Buerki, K., Lang, R., Hengartner, H. and Zinkernagel, R. M., Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 1989. 342: 559-561.
    • (1989) Nature , vol.342 , pp. 559-561
    • Pircher, H.1    Buerki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 17
  • 18
    • 0029037210 scopus 로고
    • Serial triggering of many T-cell receptors by a few peptide-MHC complexes
    • Valitutti, S., Muller, S., Cella, M., Padovan, E. and Lanzavecchia, A., Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 1995. 375: 148-151.
    • (1995) Nature , vol.375 , pp. 148-151
    • Valitutti, S.1    Muller, S.2    Cella, M.3    Padovan, E.4    Lanzavecchia, A.5
  • 19
    • 0031172162 scopus 로고    scopus 로고
    • Serial triggering of TCRs: A basis for the sensitivity and specificity of antigen recognition
    • Valitutti, S. and Lanzavecchia, A., Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition. Immunol. Today 1997. 18: 299-304.
    • (1997) Immunol. Today , vol.18 , pp. 299-304
    • Valitutti, S.1    Lanzavecchia, A.2
  • 20
    • 0030002902 scopus 로고    scopus 로고
    • Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy
    • Valitutti, S., Müller, S., Dessing, M. and Lanzavecchia, A., Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. J. Exp. Med. 1996. 183: 1917-1921.
    • (1996) J. Exp. Med. , vol.183 , pp. 1917-1921
    • Valitutti, S.1    Müller, S.2    Dessing, M.3    Lanzavecchia, A.4
  • 22
    • 0030057218 scopus 로고    scopus 로고
    • T cell activation determined by T cell receptor number and tunable thresholds
    • Viola, A. and Lanzavecchia, A., T cell activation determined by T cell receptor number and tunable thresholds. Science 1996. 273: 104-106.
    • (1996) Science , vol.273 , pp. 104-106
    • Viola, A.1    Lanzavecchia, A.2
  • 27
    • 0000351142 scopus 로고
    • Activators of proteinkinase C down-regulate and phosphorylate the T3/T cell antigen receptor complex of human T lymphocytes
    • Cantrell, D. A., Davies, A. A. and Crumpton, M. J., Activators of proteinkinase C down-regulate and phosphorylate the T3/T cell antigen receptor complex of human T lymphocytes. Proc. Natl. Acad. Sci. 1985. 82: 8158-8162.
    • (1985) Proc. Natl. Acad. Sci. , vol.82 , pp. 8158-8162
    • Cantrell, D.A.1    Davies, A.A.2    Crumpton, M.J.3
  • 29
    • 0031448209 scopus 로고    scopus 로고
    • Activation of the Lck tyrosine kinase targets cell surface T cell antigen receptors for lysosomal degradation
    • D'Oro, U., Vacchio, M. S., Weissman, A. M. and Ashwell, J. D., Activation of the Lck tyrosine kinase targets cell surface T cell antigen receptors for lysosomal degradation. Immunity 1997. 7: 619-628.
    • (1997) Immunity , vol.7 , pp. 619-628
    • D'Oro, U.1    Vacchio, M.S.2    Weissman, A.M.3    Ashwell, J.D.4
  • 30
    • 0030847844 scopus 로고    scopus 로고
    • Agonist-induced T cell receptor down-regulation: Molecular requirements and dissociation from T cell activation
    • Salio, M., Valitutti, S. and Lanzavecchia, A., Agonist-induced T cell receptor down-regulation: molecular requirements and dissociation from T cell activation. Eur. J. Immunol. 1997. 27: 1769-1773.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1769-1773
    • Salio, M.1    Valitutti, S.2    Lanzavecchia, A.3
  • 31
    • 0031183175 scopus 로고    scopus 로고
    • Inactivation of lck and loss of TCR-mediated signaling upon persistent engagement with complexes of peptide: MHC molecules
    • Lee, J. E., Cossoy, M. B., Chau, L. A., Singh, B. and Madrenas, J., Inactivation of lck and loss of TCR-mediated signaling upon persistent engagement with complexes of peptide: MHC molecules. J. Immunol. 1997. 159: 61-69.
    • (1997) J. Immunol. , vol.159 , pp. 61-69
    • Lee, J.E.1    Cossoy, M.B.2    Chau, L.A.3    Singh, B.4    Madrenas, J.5
  • 34
    • 0028913113 scopus 로고
    • lck regulates TCR expression and T cell selection
    • lck regulates TCR expression and T cell selection. Int. Immunol. 1995. 7: 617-624.
    • (1995) Int. Immunol. , vol.7 , pp. 617-624
    • Ericsson, P.-O.1    Teh, H.-S.2
  • 35
    • 0031568407 scopus 로고    scopus 로고
    • A shift from negative to positive selection of autoreactive T cells by the reduced level of TCR signal in TCR-transgenic CD3 zeta-deficient mice
    • Yamazaki, T., Arase, H., Ono, S., Ohno, H., Watanabe, H. and Saito, T., A shift from negative to positive selection of autoreactive T cells by the reduced level of TCR signal in TCR-transgenic CD3 zeta-deficient mice. J. Immunol. 1997. 158: 1634-1640.
    • (1997) J. Immunol. , vol.158 , pp. 1634-1640
    • Yamazaki, T.1    Arase, H.2    Ono, S.3    Ohno, H.4    Watanabe, H.5    Saito, T.6
  • 36
    • 0031297664 scopus 로고    scopus 로고
    • A dominant-negative mutant of the Rab5 GTPase enhances T cell signaling by interfering with TCR down-modulation in transgenic mice
    • Andre, P., Boretto, A., Hueber, A.-O., Regnier-Vigoroux, A., Gorvel, J.-P., Ferner, P. and Chavrie, P., A dominant-negative mutant of the Rab5 GTPase enhances T cell signaling by interfering with TCR down-modulation in transgenic mice. J. Immunol. 1997. 159: 5253-5263.
    • (1997) J. Immunol. , vol.159 , pp. 5253-5263
    • Andre, P.1    Boretto, A.2    Hueber, A.-O.3    Regnier-Vigoroux, A.4    Gorvel, J.-P.5    Ferner, P.6    Chavrie, P.7
  • 38
    • 0003104975 scopus 로고    scopus 로고
    • A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists
    • Lyons, D., Liebermann, S. A., Hampl, J., Boniface, J. J., Chien, Y.-H., Berg, L. J. and Davis, M. M., A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists. Immunity 1996. 5: 53-61.
    • (1996) Immunity , vol.5 , pp. 53-61
    • Lyons, D.1    Liebermann, S.A.2    Hampl, J.3    Boniface, J.J.4    Chien, Y.-H.5    Berg, L.J.6    Davis, M.M.7
  • 39
    • 0030219704 scopus 로고    scopus 로고
    • Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity
    • Schodin, B. A., Tsomides, T. J. and Kranz, D. M., Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity. Immunity 1996. 5: 137-146.
    • (1996) Immunity , vol.5 , pp. 137-146
    • Schodin, B.A.1    Tsomides, T.J.2    Kranz, D.M.3
  • 40
    • 0030914290 scopus 로고    scopus 로고
    • Understanding the mechanisms of sustained signaling and T cell activation
    • Lanzavecchia, A., Understanding the mechanisms of sustained signaling and T cell activation. J. Exp. Med. 1997. 185: 1717-1719.
    • (1997) J. Exp. Med. , vol.185 , pp. 1717-1719
    • Lanzavecchia, A.1
  • 41
    • 0030954195 scopus 로고    scopus 로고
    • Altered hapten ligands antagonize trinitrophenyl-specific cytotoxic T cells and block internalization of hapten-specific receptors
    • Preckel, T., Grimm, R., Martin, S. and Weltzien, H. U., Altered hapten ligands antagonize trinitrophenyl-specific cytotoxic T cells and block internalization of hapten-specific receptors. J. Exp. Med. 1997. 185: 1803-1813.
    • (1997) J. Exp. Med. , vol.185 , pp. 1803-1813
    • Preckel, T.1    Grimm, R.2    Martin, S.3    Weltzien, H.U.4
  • 42
    • 0027967385 scopus 로고
    • Partial T cell signaling: Altred phospho-ζ and lack of ZAP-70 recruitment in APL-induced T cell anergy
    • Sloan-Lancaster, J., Shaw, A. S., Rothbard, J. B. and Alien, P. M., Partial T cell signaling: altred phospho-ζ and lack of ZAP-70 recruitment in APL-induced T cell anergy. Cell 1994. 79: 913-922.
    • (1994) Cell , vol.79 , pp. 913-922
    • Sloan-Lancaster, J.1    Shaw, A.S.2    Rothbard, J.B.3    Alien, P.M.4
  • 43
    • 0028902752 scopus 로고
    • ζ-phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists
    • Madrenas, J., Wange, R. L., Wang, J. L., Isakov, N., Samelson, L. E. and Germain, R. N., ζ-phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science 1995. 267: 515-518.
    • (1995) Science , vol.267 , pp. 515-518
    • Madrenas, J.1    Wange, R.L.2    Wang, J.L.3    Isakov, N.4    Samelson, L.E.5    Germain, R.N.6
  • 46
    • 1842411319 scopus 로고    scopus 로고
    • T cell receptor α-chain tail is required for protein kinase C-mediated down-regulation, but not for signaling
    • Bäckström, B. T., Rubin, B., Peter, A., Tiefenthaler, G. and Palmer, E., T cell receptor α-chain tail is required for protein kinase C-mediated down-regulation, but not for signaling. Eur. J. Immunol. 1997. 27: 1433-1441.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1433-1441
    • Bäckström, B.T.1    Rubin, B.2    Peter, A.3    Tiefenthaler, G.4    Palmer, E.5
  • 47
    • 0024415579 scopus 로고
    • Comparison of phosphorylation and internalization of the antigen receptor/ CD3 complex, CD8, and class I MHC-encoded proteins. Role of the intracytoplasmic domains analyzed with hybrid CD8/class I molecules
    • published erratum appears in J. Immunol. 190 Jan 1; 144 (1): 408
    • Boyer, C., Auphan, N., Gabert, J., Blanc, D., Malissen, B. and Schmitt-Verhulst, A.-M., Comparison of phosphorylation and internalization of the antigen receptor/ CD3 complex, CD8, and class I MHC-encoded proteins. Role of the intracytoplasmic domains analyzed with hybrid CD8/class I molecules [published erratum appears in J. Immunol. 190 Jan 1; 144 (1): 408]. J. Immunol. 1989. 143: 1905-1914.
    • (1989) J. Immunol. , vol.143 , pp. 1905-1914
    • Boyer, C.1    Auphan, N.2    Gabert, J.3    Blanc, D.4    Malissen, B.5    Schmitt-Verhulst, A.-M.6
  • 48
    • 0028290315 scopus 로고
    • Evidence for protein tyrosine kinase involvement in ligand-induced TCR/CD3 internalization and surface redistribution
    • Luton, F., Buferne, M., Davoust, J., Schmitt-Verhulst, A.-M. and Boyer, C., Evidence for protein tyrosine kinase involvement in ligand-induced TCR/CD3 internalization and surface redistribution. J. Immunol. 1994. 153: 63-72.
    • (1994) J. Immunol. , vol.153 , pp. 63-72
    • Luton, F.1    Buferne, M.2    Davoust, J.3    Schmitt-Verhulst, A.-M.4    Boyer, C.5
  • 49
    • 0028851581 scopus 로고
    • Tyrosine-phosphorylated T cell receptor C chain associates with the actin cytoskeleton upon activation of mature T lymphocytes
    • Rodzial, M. M., Malissen, B. and Finkel, T. H., Tyrosine-phosphorylated T cell receptor C chain associates with the actin cytoskeleton upon activation of mature T lymphocytes. Immunity 1995. 3: 623-633.
    • (1995) Immunity , vol.3 , pp. 623-633
    • Rodzial, M.M.1    Malissen, B.2    Finkel, T.H.3
  • 50
    • 0031936042 scopus 로고    scopus 로고
    • + T cells: Compulsory cytoskeletal alterations for the triggering of an intracellular calcium response
    • + T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response. Eur. J. Immunol. 1998. 28: 716-729.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 716-729
    • Delon, J.1    Berovici, N.2    Liblau, R.3    Trautmann, A.4
  • 51
    • 0029063148 scopus 로고
    • Kinetic proofreading in T-cell receptor signal transduction
    • McKeithan, T. W., Kinetic proofreading in T-cell receptor signal transduction. Proc. Natl. Acad. Sci. USA 1995. 92: 5042-5046.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5042-5046
    • McKeithan, T.W.1
  • 53
    • 84988087266 scopus 로고
    • Fine peptide specificity of cytotoxic T lymphocytes directed against adenovirus-induced tumours and peptide-MHC binding
    • Kast, W. M. and Melief, C. J. M., Fine peptide specificity of cytotoxic T lymphocytes directed against adenovirus-induced tumours and peptide-MHC binding. Int. J. Cancer (Suppl.) 1991. 6: 90-94.
    • (1991) Int. J. Cancer (Suppl.) , vol.6 , pp. 90-94
    • Kast, W.M.1    Melief, C.J.M.2
  • 54
    • 0030587163 scopus 로고    scopus 로고
    • Selective activation of CD8 T cell effector functions by epitope variants of LCMV glycoprotein
    • Martin, S., Kohler, H., Weltzien, H. U. and Leipner, C., Selective activation of CD8 T cell effector functions by epitope variants of LCMV glycoprotein. J. Immunol. 1996. 157: 2358-2365.
    • (1996) J. Immunol. , vol.157 , pp. 2358-2365
    • Martin, S.1    Kohler, H.2    Weltzien, H.U.3    Leipner, C.4
  • 55
    • 0027983589 scopus 로고
    • Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues
    • Chen, W., Khilko, S., Fecondo, J., Margulies, D. H. and McCluskey, J., Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues. J. Exp. Med. 1994. 180: 1471-1483.
    • (1994) J. Exp. Med. , vol.180 , pp. 1471-1483
    • Chen, W.1    Khilko, S.2    Fecondo, J.3    Margulies, D.H.4    McCluskey, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.