메뉴 건너뛰기




Volumn 5, Issue 3, 1996, Pages 253-262

Cytotoxic T cell-resistant variants are selected in a virus-induced demyelinating disease

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLYCOPROTEIN; SYNTHETIC PEPTIDE;

EID: 0030249395     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80320-9     Document Type: Article
Times cited : (83)

References (61)
  • 1
    • 0028997972 scopus 로고
    • Evolution of mouse hepatitis virus (MHV) during chronic infection: Quasispecies nature of the persisting MHV RNA
    • Adami, C., Pooley, J., Glomb, J., Stecker, E., Fazal, F., Fleming, J.O., and Baker, S.C. (1995). Evolution of mouse hepatitis virus (MHV) during chronic infection: quasispecies nature of the persisting MHV RNA. Virology 209, 337-346.
    • (1995) Virology , vol.209 , pp. 337-346
    • Adami, C.1    Pooley, J.2    Glomb, J.3    Stecker, E.4    Fazal, F.5    Fleming, J.O.6    Baker, S.C.7
  • 2
    • 0021212919 scopus 로고
    • Sequence and topology of a model intracellular membrane protein, E1 glycoprotein, from a coronavirus
    • Armstrong, J., Niemann, H., Smeekens, S., Rottier, P., and Warren, G. (1984). Sequence and topology of a model intracellular membrane protein, E1 glycoprotein, from a coronavirus. Nature 308, 751-752.
    • (1984) Nature , vol.308 , pp. 751-752
    • Armstrong, J.1    Niemann, H.2    Smeekens, S.3    Rottier, P.4    Warren, G.5
  • 3
    • 0025359790 scopus 로고
    • A clustering of RNA recombination sites adjacent to a hypervariable region of the peplomer gene of murine coronavirus
    • Banner, L., Keck, J.G., and Lai, M.M.C. (1990). A clustering of RNA recombination sites adjacent to a hypervariable region of the peplomer gene of murine coronavirus. Virology 175, 548-555.
    • (1990) Virology , vol.175 , pp. 548-555
    • Banner, L.1    Keck, J.G.2    Lai, M.M.C.3
  • 4
    • 0027332584 scopus 로고
    • d-restricted cytotoxic T-lymphocyte epitope in the mouse hepatitis virus nucleocapsid protein
    • d-restricted cytotoxic T-lymphocyte epitope in the mouse hepatitis virus nucleocapsid protein. J. Virol. 67, 7041-7049.
    • (1993) J. Virol. , vol.67 , pp. 7041-7049
    • Bergmann, C.1    McMillan, M.2    Stohlman, S.A.3
  • 6
    • 0028086591 scopus 로고
    • Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope
    • Bertoletti, A., Costanzo, A., Chisari, f.V., Levero, M., Artini, M., Sette, A., Penna, A., Giuberti, T., Fiaccadori, F., and Ferrari, C. (1994a). Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope. J. Exp. Med. 180, 933-943.
    • (1994) J. Exp. Med. , vol.180 , pp. 933-943
    • Bertoletti, A.1    Costanzo, A.2    Chisari, F.V.3    Levero, M.4    Artini, M.5    Sette, A.6    Penna, A.7    Giuberti, T.8    Fiaccadori, F.9    Ferrari, C.10
  • 7
    • 0028360076 scopus 로고
    • Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells
    • Bertoletti, A., Sette, A., Chisari, F.V., Penna, A., Levrero, M., De Carli, M., Fiaccadori, F., and Ferrari, C. (1994b). Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells. Nature 369, 407-410.
    • (1994) Nature , vol.369 , pp. 407-410
    • Bertoletti, A.1    Sette, A.2    Chisari, F.V.3    Penna, A.4    Levrero, M.5    De Carli, M.6    Fiaccadori, F.7    Ferrari, C.8
  • 8
    • 0021344138 scopus 로고
    • Murine hepatitis virus-4 (strain JHM)-induced neurologic disease is modulated in vivo by monoclonal antibody
    • Buchmeier, M.J., Lewicki, H.A., Talbot, P.J., and Knobler, R.L. (1984). Murine hepatitis virus-4 (strain JHM)-induced neurologic disease is modulated in vivo by monoclonal antibody. Virology 132, 261-270.
    • (1984) Virology , vol.132 , pp. 261-270
    • Buchmeier, M.J.1    Lewicki, H.A.2    Talbot, P.J.3    Knobler, R.L.4
  • 9
    • 0027170142 scopus 로고
    • Antigen-selected T-cell receptor diversity and self-nonself homology
    • Casanova, J.-L., and Maryanski, J. (1993). Antigen-selected T-cell receptor diversity and self-nonself homology. Immunol. Today 14, 391-394.
    • (1993) Immunol. Today , vol.14 , pp. 391-394
    • Casanova, J.-L.1    Maryanski, J.2
  • 10
    • 0028824901 scopus 로고
    • CD8+ T cell epitopes within the surface glycoprotein of a neurotropic coronavirus and correlation with pathogenicity
    • Castro, R.F., and Perlman, S. (1995). CD8+ T cell epitopes within the surface glycoprotein of a neurotropic coronavirus and correlation with pathogenicity. J. Virol. 69, 8127-8131.
    • (1995) J. Virol. , vol.69 , pp. 8127-8131
    • Castro, R.F.1    Perlman, S.2
  • 11
    • 0028297362 scopus 로고
    • Coronavirus-induced demyelination occurs in the presence of virus-specific cytotoxic T cells
    • Castro, R.F., Evans, G.D., Jaszewski, A., and Perlman, S. (1994). Coronavirus-induced demyelination occurs in the presence of virus-specific cytotoxic T cells. Virology 200, 733-743.
    • (1994) Virology , vol.200 , pp. 733-743
    • Castro, R.F.1    Evans, G.D.2    Jaszewski, A.3    Perlman, S.4
  • 12
    • 0028123067 scopus 로고
    • Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 nef protein
    • Couillin, I., Culmann-Penciolelli, B., Gomard, E., Choppin, J., Levy, J.-P., Guillet, J.-G., and Saragosti, S. (1994). Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 nef protein. J. Exp. Med. 180, 1129-1134.
    • (1994) J. Exp. Med. , vol.180 , pp. 1129-1134
    • Couillin, I.1    Culmann-Penciolelli, B.2    Gomard, E.3    Choppin, J.4    Levy, J.-P.5    Guillet, J.-G.6    Saragosti, S.7
  • 13
    • 0022474546 scopus 로고
    • Site-specific alteration of murine hepatitis virus type 4 peplomer glycoprotein E2 results in reduced neurovirulence
    • Dalziel, R.G., Lampert, P.W., Talbot, P.J., and Buchmeier, M.J. (1986). Site-specific alteration of murine hepatitis virus type 4 peplomer glycoprotein E2 results in reduced neurovirulence. J. Virol. 59, 463-471.
    • (1986) J. Virol. , vol.59 , pp. 463-471
    • Dalziel, R.G.1    Lampert, P.W.2    Talbot, P.J.3    Buchmeier, M.J.4
  • 14
    • 0026599764 scopus 로고
    • Flanking sequence influences the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes
    • Eisenlohr, L.C., Yewdell, J.W., and Bennink, J.R. (1992). Flanking sequence influences the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes. J. Exp. Med. 175, 481-487.
    • (1992) J. Exp. Med. , vol.175 , pp. 481-487
    • Eisenlohr, L.C.1    Yewdell, J.W.2    Bennink, J.R.3
  • 15
    • 0025855156 scopus 로고
    • Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
    • Falk, K., Rötzschke, O., Stevanovic, S., Jung, G., and Rammensee, H.-G. (1991). Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 351, 290-296.
    • (1991) Nature , vol.351 , pp. 290-296
    • Falk, K.1    Rötzschke, O.2    Stevanovic, S.3    Jung, G.4    Rammensee, H.-G.5
  • 16
    • 0024590638 scopus 로고
    • Monoclonal antibodies to the matrix (E1) glycoprotein of mouse hepatitis virus protect mice from encephalitis
    • Fleming, J.O., Shubin, R.A., Sussman, M.A., Casteel, N., and Stohlman, S.A. (1989). Monoclonal antibodies to the matrix (E1) glycoprotein of mouse hepatitis virus protect mice from encephalitis. Virology 168, 162-167.
    • (1989) Virology , vol.168 , pp. 162-167
    • Fleming, J.O.1    Shubin, R.A.2    Sussman, M.A.3    Casteel, N.4    Stohlman, S.A.5
  • 17
    • 0029120420 scopus 로고
    • Viral mutations, TCR antagonism and escape from the immune response
    • Franco, A., Ferrari, C., Sette, A., and Chisari, F.V. (1995). Viral mutations, TCR antagonism and escape from the immune response. Curr. Opin. Immunol. 7, 524-531.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 524-531
    • Franco, A.1    Ferrari, C.2    Sette, A.3    Chisari, F.V.4
  • 18
    • 0026730940 scopus 로고
    • Design of high-affinity MHC-specific antagonist peptides that inhibit cytotoxic T-lymphocyte activity: Implications for control of viral disease
    • Gairin, J., and Oldstone, M. (1992). Design of high-affinity MHC-specific antagonist peptides that inhibit cytotoxic T-lymphocyte activity: implications for control of viral disease. J. Virol. 66, 6755-6762.
    • (1992) J. Virol. , vol.66 , pp. 6755-6762
    • Gairin, J.1    Oldstone, M.2
  • 20
    • 0029044542 scopus 로고
    • Mouse hepatitis virus A59-induced demyelination can occur in the absence of CD8+ T cells
    • Gombold, J., Sutherland, R., Lavi, E., Paterson, Y., and Weiss, S.R. (1995). Mouse hepatitis virus A59-induced demyelination can occur in the absence of CD8+ T cells. Microb. Pathog. 18, 211-221.
    • (1995) Microb. Pathog. , vol.18 , pp. 211-221
    • Gombold, J.1    Sutherland, R.2    Lavi, E.3    Paterson, Y.4    Weiss, S.R.5
  • 21
    • 0009571465 scopus 로고
    • Temperature-sensitive mutants of mouse hepatitis virus produce a high incidence of demyelination
    • Haspel, M.V., Lampert, P.W., and Oldstone, M.B.A. (1978). Temperature-sensitive mutants of mouse hepatitis virus produce a high incidence of demyelination. Proc. Natl. Acad. Sci. USA 75, 4033-4036.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 4033-4036
    • Haspel, M.V.1    Lampert, P.W.2    Oldstone, M.B.A.3
  • 23
    • 0025560428 scopus 로고
    • Localization of virus and antibody response in mice infected persistently with MHV-JHM
    • Jacobsen, G., and Perlman, S. (1990). Localization of virus and antibody response in mice infected persistently with MHV-JHM. Adv. Exp. Med. Biol. 276, 573-578.
    • (1990) Adv. Exp. Med. Biol. , vol.276 , pp. 573-578
    • Jacobsen, G.1    Perlman, S.2
  • 24
    • 0026787326 scopus 로고
    • b-restricted ovalbumin peptide and an assessment of the predictive power of MHC-binding motifs
    • b-restricted ovalbumin peptide and an assessment of the predictive power of MHC-binding motifs. Eur. J. Immunol. 22, 2663-2667.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2663-2667
    • Jameson, S.1    Bevan, M.2
  • 25
    • 0028323247 scopus 로고
    • Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire
    • Kalams, S., Johnson, R., Trocha, A., Dynan, M., Ngo, H., D'Aquila, R., Kurnick, J., and Walker, B. (1994). Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire. J. Exp. Med. 179, 1261-1271.
    • (1994) J. Exp. Med. , vol.179 , pp. 1261-1271
    • Kalams, S.1    Johnson, R.2    Trocha, A.3    Dynan, M.4    Ngo, H.5    Aquila, R.6    Kurnick, J.7    Walker, B.8
  • 27
    • 0019964287 scopus 로고
    • Virus persistence and recurring demyelination produced by a temperature-sensitive mutant of MHV-4
    • Knobler, R.L., Lambert, P.W., and Oldstone, M.B.A. (1982). Virus persistence and recurring demyelination produced by a temperature-sensitive mutant of MHV-4. Nature 298, 279-280.
    • (1982) Nature , vol.298 , pp. 279-280
    • Knobler, R.L.1    Lambert, P.W.2    Oldstone, M.B.A.3
  • 28
    • 0025940132 scopus 로고
    • Nucleocapsid or spike protein-specific CD4+ T lymphocytes protect against coronavirus-induced encephalomyelitis in the absence of CD8+ T cells
    • Körner, H., Schliephake, A., Winter, J., Zimprich, F., Lassmann, H., Sedgwick, J., Siddell, S., and Wege, H. (1991). Nucleocapsid or spike protein-specific CD4+ T lymphocytes protect against coronavirus-induced encephalomyelitis in the absence of CD8+ T cells. J. Immunol. 147, 2317-2323.
    • (1991) J. Immunol. , vol.147 , pp. 2317-2323
    • Körner, H.1    Schliephake, A.2    Winter, J.3    Zimprich, F.4    Lassmann, H.5    Sedgwick, J.6    Siddell, S.7    Wege, H.8
  • 29
    • 0000579872 scopus 로고
    • Pathogenesis of a neurotropic murine coronavirus, strain JHM in the central nervous system of mice. Semin
    • Kyuwa, S., and Stohlman, S.A. (1990). Pathogenesis of a neurotropic murine coronavirus, strain JHM in the central nervous system of mice. Semin. Virol. 1, 273-280.
    • (1990) Virol. , vol.1 , pp. 273-280
    • Kyuwa, S.1    Stohlman, S.A.2
  • 30
    • 0021343397 scopus 로고
    • Experimental demyelination produced by the A59 strain of MHV
    • Lavi, E., Gilden, D., Wroblewska, Z., Rorke, L., and Weiss, S. (1984). Experimental demyelination produced by the A59 strain of MHV. Neurology 34, 597-603.
    • (1984) Neurology , vol.34 , pp. 597-603
    • Lavi, E.1    Gilden, D.2    Wroblewska, Z.3    Rorke, L.4    Weiss, S.5
  • 33
    • 0030020130 scopus 로고    scopus 로고
    • Single-cell PCR analysis of TCR repertoires selected by antigen in vivo: A high magnitude CD8 response is comprised of very few clones
    • Maryanski, J., Jongeneel, C., Bucher, P., Casanova, J.-L., and Walker, P. (1996). Single-cell PCR analysis of TCR repertoires selected by antigen in vivo: a high magnitude CD8 response is comprised of very few clones. Immunity 4, 47-55.
    • (1996) Immunity , vol.4 , pp. 47-55
    • Maryanski, J.1    Jongeneel, C.2    Bucher, P.3    Casanova, J.-L.4    Walker, P.5
  • 35
    • 0029960939 scopus 로고    scopus 로고
    • AIDS pathogenesis: A finite immune response to blame?
    • Miedema, F., and Klein, M.R. (1996). AIDS pathogenesis: a finite immune response to blame? Science 272, 505-506.
    • (1996) Science , vol.272 , pp. 505-506
    • Miedema, F.1    Klein, M.R.2
  • 36
    • 0024514101 scopus 로고
    • Characterization of coronavirus JHM variants isolated from Wistar Furth rats with a viral-induced demyelinating disease
    • Morris, V., Tieszer, C., Mackinnon, J., and Percy, D. (1989). Characterization of coronavirus JHM variants isolated from Wistar Furth rats with a viral-induced demyelinating disease. Virology 169, 127-136.
    • (1989) Virology , vol.169 , pp. 127-136
    • Morris, V.1    Tieszer, C.2    Mackinnon, J.3    Percy, D.4
  • 37
    • 0028930288 scopus 로고
    • Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus
    • Moskophidis, D., and Zinkernagel, R.M. (1995). Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus. J. Virol. 69, 2187-2193.
    • (1995) J. Virol. , vol.69 , pp. 2187-2193
    • Moskophidis, D.1    Zinkernagel, R.M.2
  • 38
    • 0029985351 scopus 로고    scopus 로고
    • Population dynamics of immune responses to persistent viruses
    • Nowak, M.A., and Bangham, C.R.M. (1996). Population dynamics of immune responses to persistent viruses. Science 272, 74-79.
    • (1996) Science , vol.272 , pp. 74-79
    • Nowak, M.A.1    Bangham, C.R.M.2
  • 40
    • 0024831463 scopus 로고
    • Sequence analysis reveals extensive polymorphism and evidence of deletions within the E2 glycoprotein gene of several strains of murine hepatitis virus
    • Parker, S.E., Gallagher, T.M., and Buchmeier, M.J. (1989). Sequence analysis reveals extensive polymorphism and evidence of deletions within the E2 glycoprotein gene of several strains of murine hepatitis virus. Virology 173, 664-673.
    • (1989) Virology , vol.173 , pp. 664-673
    • Parker, S.E.1    Gallagher, T.M.2    Buchmeier, M.J.3
  • 41
    • 0027941162 scopus 로고
    • Cytokine induction during T-cell-mediated clearance of mouse hepatitis virus from neurons in vivo
    • Pearce, B.D., Hobbs, M.V., McGraw, T.S., and Buchmeier, M.J. (1994). Cytokine induction during T-cell-mediated clearance of mouse hepatitis virus from neurons in vivo. J. Virol. 68, 5483-5495.
    • (1994) J. Virol. , vol.68 , pp. 5483-5495
    • Pearce, B.D.1    Hobbs, M.V.2    McGraw, T.S.3    Buchmeier, M.J.4
  • 42
    • 0023098948 scopus 로고
    • Late onset, symptomatic, demyelinating encephalomyelitis in mice infected with MHV-JHM in the presence of maternal antibody
    • Perlman, S., Schelper, R., Bolger, E., and Ries, D. (1987). Late onset, symptomatic, demyelinating encephalomyelitis in mice infected with MHV-JHM in the presence of maternal antibody. Microb. Pathog. 2, 185-194.
    • (1987) Microb. Pathog. , vol.2 , pp. 185-194
    • Perlman, S.1    Schelper, R.2    Bolger, E.3    Ries, D.4
  • 43
    • 0025364080 scopus 로고
    • Identification of the spinal cord as a major site of persistence during chronic infection with a murine coronavirus
    • Perlman, S., Jacobsen, G., Olson, A.L., and Afifi, A. (1990). Identification of the spinal cord as a major site of persistence during chronic infection with a murine coronavirus. Virology 175, 418-426.
    • (1990) Virology , vol.175 , pp. 418-426
    • Perlman, S.1    Jacobsen, G.2    Olson, A.L.3    Afifi, A.4
  • 45
    • 0024992268 scopus 로고
    • Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo
    • Pircher, H., Moskophidis, D., Rohrer, U., Burki, K., Hengartner, H., and Zinkernagel, R. (1990). Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo. Nature 346, 629-633.
    • (1990) Nature , vol.346 , pp. 629-633
    • Pircher, H.1    Moskophidis, D.2    Rohrer, U.3    Burki, K.4    Hengartner, H.5    Zinkernagel, R.6
  • 46
    • 0029166085 scopus 로고
    • Hepatitis B virus (HBV) sequence variation in cytotoxic T lymphocyte epitopes is not common in patients with chronic HBV infection
    • Rehermann, B., Pasquinelli, C., Mosier, S., and Chisari, F. (1995). Hepatitis B virus (HBV) sequence variation in cytotoxic T lymphocyte epitopes is not common in patients with chronic HBV infection. J. Clin. Invest. 96, 1527-1534.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1527-1534
    • Rehermann, B.1    Pasquinelli, C.2    Mosier, S.3    Chisari, F.4
  • 48
    • 0025006862 scopus 로고
    • Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro
    • Schumacher, T.N.M., Heemels, M.-T., Neefjes, J.J., Kast, W.M., Melief, C.J.M., and Ploegh, H.L. (1990). Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro. Cell 62, 563-567.
    • (1990) Cell , vol.62 , pp. 563-567
    • Schumacher, T.N.M.1    Heemels, M.-T.2    Neefjes, J.J.3    Kast, W.M.4    Melief, C.J.M.5    Ploegh, H.L.6
  • 49
    • 0018935506 scopus 로고
    • In vivo and in vitro models of demyelinating diseases. III. JHM virus infection of rats
    • Sorensen, O., Perry, D., and Dales, S. (1980). In vivo and in vitro models of demyelinating diseases. III. JHM virus infection of rats. Arch. Neurol. 37, 478-484.
    • (1980) Arch. Neurol. , vol.37 , pp. 478-484
    • Sorensen, O.1    Perry, D.2    Dales, S.3
  • 50
    • 0022655482 scopus 로고
    • In vivo effects of coronavirus-specific T cell clones: DTH inducer cells prevent a lethal infection but do not inhibit virus replication
    • Stohlman, S.A., Matsushima, G.K., Casteel, N., and Weiner, L.P. (1986). In vivo effects of coronavirus-specific T cell clones: DTH inducer cells prevent a lethal infection but do not inhibit virus replication. J. Immunol. 136, 3052-3056.
    • (1986) J. Immunol. , vol.136 , pp. 3052-3056
    • Stohlman, S.A.1    Matsushima, G.K.2    Casteel, N.3    Weiner, L.P.4
  • 51
    • 0028888169 scopus 로고
    • Mouse hepatitis virus-specific cytotoxic T lymphocytes protect from lethal infection without eliminating virus from the central nervous system
    • Stohlman, S.A., Bergmann, C.C., van der Veen, R.C., and Hinton, D.R. (1995). Mouse hepatitis virus-specific cytotoxic T lymphocytes protect from lethal infection without eliminating virus from the central nervous system. J. Virol. 69, 684-694.
    • (1995) J. Virol. , vol.69 , pp. 684-694
    • Stohlman, S.A.1    Bergmann, C.C.2    Van Der Veen, R.C.3    Hinton, D.R.4
  • 52
    • 0028852336 scopus 로고
    • Spread of a neurotropic coronavirus to spinal cord white matter via neurons and astrocytes
    • Sun, N., and Perlman, S. (1995). Spread of a neurotropic coronavirus to spinal cord white matter via neurons and astrocytes. J. Virol. 69, 633-641.
    • (1995) J. Virol. , vol.69 , pp. 633-641
    • Sun, N.1    Perlman, S.2
  • 53
    • 0023492620 scopus 로고
    • Comparative analysis of coronavirus JHM-induced demyelinating encephalomyelitis in Lewis and Brown Norway rats
    • Watanabe, R., Wege, H., and ter Meulen, V. (1987). Comparative analysis of coronavirus JHM-induced demyelinating encephalomyelitis in Lewis and Brown Norway rats. Lab. Invest. 57, 375-384.
    • (1987) Lab. Invest. , vol.57 , pp. 375-384
    • Watanabe, R.1    Wege, H.2    Ter Meulen, V.3
  • 54
    • 0029146911 scopus 로고
    • Immunopathological aspects of coronavirus infection. Springer Semin
    • Wege, H. (1995). Immunopathological aspects of coronavirus infection. Springer Semin. Immunopathol. 17, 133-148.
    • (1995) Immunopathol. , vol.17 , pp. 133-148
    • Wege, H.1
  • 55
    • 0025047026 scopus 로고
    • Effective clearance of mouse hepatitis virus from the central nervous system requires both CD4+ and CD8+ T cells
    • Williamson, J.S., and Stohlman, S.A. (1990). Effective clearance of mouse hepatitis virus from the central nervous system requires both CD4+ and CD8+ T cells. J. Virol. 64, 4589-4592.
    • (1990) J. Virol. , vol.64 , pp. 4589-4592
    • Williamson, J.S.1    Stohlman, S.A.2
  • 56
    • 0025875361 scopus 로고
    • Characterization of brain-infiltrating mononuclear cells during infection with mouse hepatitis virus strain JHM
    • Williamson, J.S., Sykes, K.C., and Stohlman, S.A. (1991). Characterization of brain-infiltrating mononuclear cells during infection with mouse hepatitis virus strain JHM. J. Neuroimmunol. 32, 199-207.
    • (1991) J. Neuroimmunol. , vol.32 , pp. 199-207
    • Williamson, J.S.1    Sykes, K.C.2    Stohlman, S.A.3
  • 58
    • 0028966897 scopus 로고
    • Identification of a CD4+ T cell epitope within the M protein of a neurotropic coronavirus
    • Xue, S., Jaszewski, A., and Perlman, S. (1995). Identification of a CD4+ T cell epitope within the M protein of a neurotropic coronavirus. Virology 208, 173-179.
    • (1995) Virology , vol.208 , pp. 173-179
    • Xue, S.1    Jaszewski, A.2    Perlman, S.3
  • 59
    • 0025970358 scopus 로고
    • Protection of mice from a lethal coronavirus infection in the central nervous system by adoptive transfer of virus-specific T cell clones
    • Yamaguchi, K., Goto, N., Kyuwa, S., Hayami, M., and Toyoda, Y. (1991). Protection of mice from a lethal coronavirus infection in the central nervous system by adoptive transfer of virus-specific T cell clones. J. Neuroimmunol. 32, 1-9.
    • (1991) J. Neuroimmunol. , vol.32 , pp. 1-9
    • Yamaguchi, K.1    Goto, N.2    Kyuwa, S.3    Hayami, M.4    Toyoda, Y.5
  • 61
    • 0030024279 scopus 로고    scopus 로고
    • Immunology taught by viruses
    • Zinkernagel, R.M. (1996). Immunology taught by viruses. Science 277, 173-178.
    • (1996) Science , vol.277 , pp. 173-178
    • Zinkernagel, R.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.