Effects of amiloride on gustatory quality descriptions and temporal patterns produced by NaCl

Chemical Senses

Volumn 23, Issue 5, 1998, Pages 501-511

  Halpern, Bruce P ^a   Darlington, Richard B ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMILORIDE; CAFFEINE; SODIUM CHLORIDE;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GUSTATORY SYSTEM; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; TASTE; TEMPORAL SUMMATION; TONGUE;

ADOLESCENT; ADULT; AMILORIDE; CAFFEINE; FEMALE; HUMANS; MALE; PREGNANCY; SODIUM CHLORIDE; TASTE; TIME FACTORS;

EID: 0031687080     PISSN: 0379864X     EISSN: None     Source Type: Journal    
DOI: 10.1093/chemse/23.5.501     Document Type: Article

References (46)

1. Anand, K.K. and Zuniga, J.R. (1997) Effect of amiloride on suprathreshold NaCl, LiCl, and KCl salt taste in humans. Physiol. Behav., 62, 925-929.
2. Brand, J.G., Teeter, J.H., Cagan, R.H. and Kare, M.R. (eds) (1989) Chemical Senses. Volume 1. Receptor Events and Transduction in Taste and Olfaction. Marcel Dekker, New York.
3. Breslin, P.A.S. (1996) Interactions among salty, sour and bitter compounds. Food Qual. Pref., 7, 390-399.
4. Breslin, P.A.S. and Beauchamp, G.K. (1995) Suppression of bitterness by sodium: variation among bitter taste stimuli. Chem. Senses, 20, 609-623.
5. Brosvic, G. M. and Rowe, M.M. (1992) Methyl xanthine, adenosine, and human taste responsivity. Physiol. Behav., 52, 559-563.
6. Darlington, R.B. (1990) Regression and Linear Models. McGraw-Hill, New York.
7. Darlington, R.B. (1998) A Meta-Analytic 'p-pooler' with Three Advantages. http://www.psych.cornell.edu/Darlington/pprod1.htm.
8. Delconte, J.D., Kelling, S.T. and Halpern, B.P. (1992) Speed and consistency of human decisions to swallow or spit sweet and sour solutions. Experientia, 48, 1106-1109.
9. Delwiche, J.F., Halpern, B.P. and Lee, M.Y. (1996) A comparison of tip of the tongue and sip & spit screening procedures. Food Qual. Pref., 7, 293-297.
10. Denton, D. (1982) The Hunger for Salt. Springer-Verlag, Berlin.
11. DeSimone, J.A., Heck, G. L. and DeSimone, S.K. (1981) Active ion transport in dog tongue: a possible role in taste. Science, 214, 1039-1041.
12. Desor, J.A. and Finn, J. (1989) Effects of amiloride on salt taste in humans. Chem. Senses, 14, 793-803.
13. Friedman, M.I., Tordoff, M.G. and Kare, M.R. (eds) (1991) Chemical Senses. Volume 4, Appetite and Nutrition. Marcel Dekker, New York.
14. + channel. Physiol. Rev., 68, 309-373.
15. Halpern, B.P. (1985) Time as a factor in gustation: temporal patterns of taste stimulation and response. In Pfaff, D.W. (ed.), Taste, Olfaction, and the Central Nervous System. The Rockefeller University Press, New York, pp. 181-209.
16. Halpern, B.P. (1987) Human judgments of MSG taste: quality and reaction times. In Kawamura, Y. and Kare, M.R. (eds), Umami: a Basic Taste. Marcel Dekker, New York, pp. 325-354.
17. Halpern, B.P. (1991 ) More than meets the tongue: temporal characteristics of taste intensity and quality. In Lawless, H. T. and Klein, B.P. (eds), Sensory Science Theory and Applications in Foods. Marcel Dekker, New York, pp. 37-105.
18. Halpern, B.P. (1994) Temporal patterns of perceived tastes differ from liquid flow at the tongue. In Kurihara, K., Suzuki, N. and Ogawa, H. (eds), Olfaction and Taste XI. Springer-Verlag, Tokyo, pp. 297-300.
19. Halpern, B.P. (1997) Psychophysics of taste. In Beauchamp, G.K. and Bartoshuk, L.M. (eds), Tasting and Smelling. Handbook of Perception and Cognition, 2nd edn. Academic Press, San Diego, CA, pp. 77-123.
20. Halpern, B.P. (1998) Amiloride and vertebrate gustatory responses to NaCl. Neurosci. Biobehav. Rev., in press.
21. Halpern, B.P., Kelling, S.T., Davis, J., Dorries, K.M., Haq, A. and Meltzer, J.S. (1992) Effects of amiloride on human taste responses to NaCl: time-intensity and taste quality descriptor measures. Chem. Senses, 17, 637 (abstract).
22. Halpern, B.P., Meltzer, J.S. and Darlington, R.B. (1993) Effects of amiloride on tracked taste intensity and on taste quality descriptions of NaCl: individual differences and dose-response effects. Chem. Senses, 18, 566 (abstract).
23. Halpern, B.P., Meltzer, J.S., Lee, M. and Darlington, R.B. (1995) Amiloride and judgments of NaCl taste: no consistent effects on either time course of taste intensity or reports of salty taste. Chem. Senses, 20, 701-702 (abstract).
24. Halpern, B.P., Meltzer, J.S., Lee, M. and Darlington, R.B. (1996) Amiloride and judgments of NaCl taste: no effects on tracked taste intensity. Chem. Senses, 21, 611 (abstract).
25. Kamen, J.M., Pilgrim, F.J., Gutman, N.J. and Kroll, B.J. (1961) Interactions of suprathreshold taste stimuli. J. Exp. Psychol., 62, 348-356.
26. Kelling, S.T. and Halpern, B.P. (1986) Physical characteristics of open flow and closed flow taste delivery apparatus. Chem. Senses, 11, 89-104.
27. Kelling, S.T. and Halpern, B.P. (1988) Taste judgments and gustatory stimulus duration: taste quality, taste intensity, and reaction time. Chem. Senses, 13, 559-586.
28. Kinnamon, S.C. (1996) Taste transduction: linkage between molecular mechanisms and psychophysics. Food Qual. Pref., 7, 153-159.
29. Lindemann, B. (1995) Sweet and salty: transduction in taste. News Physiol. Sci., 10, 166-170.
30. 2+ exchange. Pharmacol. Res., 25, 303-310.
31. Margolskee, R.F. (1993) The molecular biology of taste transduction. BioEssays, 15, 645-650.
32. McCutcheon, N.B. (1992) Human psychophysical studies of saltiness suppression by amiloride. Physiol. Behav., 51, 1069-1074.
33. Mela, D.J. (1989) Biner taste intensity: the effect of tastant and thiourea taster status. Chem. Senses, 14, 131-135.
34. O'Mahony, M., Rothman, L., Ellison, J., Shaw, D. and Buteau, L. (1990) Taste descriptive analysis: concept formation, alignment and appropriateness. J. Sensory Stud., 5, 71-103.
35. + receptor mechanisms. Chem. Senses, 20, 37-46.
36. Ossebaard, C.A. and Smith, D.V. (1996) Amiloride suppresses the sourness of NaCl and LiCl. Physiol. Behav., 60, 1317-1322.
37. Ossebaard, C.A., Polet, I. A. and Smith, D.V. (1997) Amiloride effects on taste quality: comparison of single and multiple response category procedures. Chem. Senses, 22, 267-275.
38. Rubico, S.M. and McDaniel, M.R. (1992). Sensory evaluation of acids by free-choice profiling. Chem. Senses, 17, 273-289.
39. Schiffman, S.S. (1988) Taste transduction and modulation. News Physiol. Sci., 3, 109-112.
40. + salts and sweeteners. Proc. Natl Acad. Sci. USA, 80, 6136-6140.
41. Schiffman, S.S., Gill, J.M. and Diaz, C. (1985) Methyl xanthines enhance taste: evidence for modulation of taste by adenosine receptor. Pharmacol. Biochem. Behav., 22, 195-204.
42. Simon, S.A. and Roper, S.D. (eds) (1993) Mechanisms of Taste Transduction. CRC Press, Boca Raton, FL.
43. + channels. Annu. Rev. Physiol., 53, 509-530.
44. Smith, D.V. and Ossebaard, C.A. (1995) Amiloride suppression of the taste intensity of sodium chloride: evidence from direct magnitude scaling. Physiol. Behav., 57, 773-777.
45. Tennissen, A.M. (1992) Amiloride reduces intensity responses of human fungiform papillae. Physiol. Behav., 51, 1061-1068.
46. Tennissen, A.M. and McCutcheon, N.B. (1996) Anterior tongue stimulation with amiloride suppresses NaCI saltiness, but not citric acid sourness in humans. Chem. Senses, 21, 113-120.