Antiretroviral activity and pharmacokinetics in mice of oral bis(pivaloyloxymethyl)-9-(2-phosphonylmethoxyethyl)adenine, the bis(pivaloyloxymethyl) ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine

Antimicrobial Agents and Chemotherapy

Volumn 40, Issue 1, 1996, Pages 22-28

  Naesens, Lieve ^a   Balzarini, Jan ^a   Bischofberger, Norbert ^b   De Clercq, Erik ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b GILEAD SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

9 (2 PHOSPHONOMETHOXYETHYL)ADENINE DIPHENYL ESTER; ADEFOVIR; ADEFOVIR DIPIVOXIL; ANTIVIRUS AGENT; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; COMBINED IMMUNODEFICIENCY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG FORMULATION; DRUG SYNTHESIS; FEMALE; MOLONEY MURINE SARCOMA ONCOVIRUS; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; VIRUS INHIBITION;

EID: 0030045493     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.1.22     Document Type: Article

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