Entropically driven enhancement of cleavage activity of a DNA-armed hammerhead ribozyme: Mechanism of action of hammerhead ribozymes

Journal of Organic Chemistry

Volumn 62, Issue 26, 1997, Pages 9138-9147

  Warashina, Masaki ^a,b,c   Takagi, Yasuomi ^b,c   Sawata, Shinya ^b,c   Zhou, De Min ^a,b,c   Kuwabara, Tomoko ^a,b,c   Taira, Kazunari ^a,b,c  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b NATL INST BIOSCI HUM TECHNOL   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; OXYGEN; PHOSPHATE; RIBOZYME; RNA;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; DRUG MECHANISM; ENTROPY; ENZYME ACTIVITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; KINETICS; TEMPERATURE; THERMODYNAMICS;

EID: 0031449332     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9712411     Document Type: Article

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