Magnesium-mediated conversion of an inactive form of a hammerhead ribozyme to an active complex with its substrate: An investigation by NMR spectroscopy

Journal of Biological Chemistry

Volumn 271, Issue 16, 1996, Pages 9447-9454

  Orita, Masaya ^a   Vinayak, Ravi ^b   Andrus, Alex ^b   Warashina, Masaki ^c,e   Chiba, Atsushi ^d   Kaniwa, Hidetoshi ^a   Nishikawall, Fumiko ^c   Nishikawa, Satoshi ^c   Taira, Kazunari ^c,e  

^a ASTELLAS PHARMA INC   (Japan)

^b PERKINELMER INC   (United States)

^c NATL INST BIOSCI HUM TECHNOL   (Japan)

^d IBARAKI UNIVERSITY   (Japan)

^e UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM; RIBOZYME;

ARTICLE; BASE PAIRING; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME INACTIVATION; ENZYME SUBSTRATE COMPLEX; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING;

BASE COMPOSITION; BASE SEQUENCE; KINETICS; MAGNESIUM; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; RNA, CATALYTIC; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 0029997458     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.16.9447     Document Type: Article

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