Regulation of leptin production in cultured mature white adipocytes

Hormone and Metabolic Research

Volumn 28, Issue 12, 1996, Pages 685-689

  Hardie, L J ^a   Guilhot, N ^a   Trayhurn, P ^a  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

dexamethasone; ELISA; growth hormone; IGF 1; insulin; isoprenaline; tumor necrosis factor

Indexed keywords

DACTINOMYCIN; DEXAMETHASONE; GROWTH HORMONE; INSULIN; ISOPRENALINE; LEPTIN; PROPRANOLOL; SOMATOMEDIN C; TUMOR NECROSIS FACTOR;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION REGULATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030455365     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-979878     Document Type: Article

References (33)

1. Trayhurn P, Rayner DV: Hormones and the ob gene-product (leptin) in the control of energy-balance. Biochem Soc Transac 24: 565-570 (1996).
2. Zhang YY, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homolog. Nature 374: 479-479 (1994).
3. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S, Kern PA, Friedman JM: Leptin levels in human and rodent - measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nature Med 1: 1155-1161 (1995).
4. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F: Effects of the obese gene-product on body-weight regulation in ob/ob mice. Science 269: 540-543 (1995).
5. Rentsch J, Levens N, Chiesi M: Recombinant ob-gene product reduces food-intake in fasted mice. Biochem Biophys Res Comm 214: 131-136 (1995).
6. Cioffi JA, Shafer AW, Zupancic TJ, Smith-Gbur J, Mikhail A, Platika D, Snodgrass HR: Novel B219/Ob receptor isoforms - possible role of leptin in hematopoiesis and reproduction. Nature Med 2: 585-589 (1996).
7. Ghilardi N, Ziegler S, Wiestner, A, Stoffel R, Heim MH, Skoda RC: Defective STAT signaling by the leptin receptor in diabetic mice. Proc Natl Acad Sci USA 93: 6231-6235 (1996).
8. Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Trayhurn P: Localization of leptin receptor messenger-RNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain-regions by in-situ hybridization. FEBS Letters 387: 113-116 (1996).
9. Hardie LJ, Rayner DV, Holmes S, Trayhurn P: Circulating leptin levels are modulated by fasting, cold-exposure and insulin administration in lean but not zucker (fa/fa) rats as measured by ELISA. Biochem Biophys Res Comm 223: 660-665 (1996)
10. Devos P, Saladin R, Auwerx J, Staels B: Induction of Ob gene-expression by corticosteroids is accompanied by body-weight loss and reduced food-intake. J Biol Chem 270: 15958-15961 (1995).
11. Trayhurn P, Duncan JS, Rayner DV: Acute cold-induced suppression of ob (obese) gene-expression in white adipose-tissue of mice - mediation by the sympathetic system. Biochem J 311: 729-733 (1995).
12. Grunfeld C, Zhano C, Fuller J, Pollock A, Moser A, Friedman J, Feingold KR: Endotoxin and cytokines induce expression of leptin, the ob gene-product, in hamsters - a role for leptin in the anorexia of infection. J Clin Invest 97: 2152-2157 (1996).
13. Dagogojack S, Fanelli C, Paramore D, Brothers J, Landt M: Plasma leptin and insulin relationships in obese and nonobese humans. Diabetes 45: 695-698 (1996).
14. Vidal H, Auboeuf D, De Vos P, Staels B, Riou JP, Auwerx J, Laville M: The expression of ob gene is not acutely regulated by insulin and fasting in human abdominal subcutaneous adipose tissue. J Clin Invest 98: 251-255 (1996).
15. Leroy P, Dessolin S, Villageois P, Moon BC, Friedman JM, Ailhaud G, Dani C: Expression of ob gene in adipose-cells - regulation by insulin. J Biol Chem 271: 2365-2368 (1996).
16. Maffei M, Fei H, Lee GH, Dani C, Leroy P, Zhang YY, Proena R, Negrel R, Ailhaud G, Friedman JM: Increased expression in adipocytes of Ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus. Proc Natl Acad Sci USA 92: 6957-6960 (1995).
17. Mitchell SE, Rees WD, Tadayyon M, Arch JRS, Trayhurn P: Ob gene expression in 3T3-L1 cells: comparison with markers of adipocyte differentiation. Int J Obes 20: 129 (1996).
18. Kallen CB, Lazar MA: Antidiabetic thiazolidinediones inhibit leptin (ob) gene-expression in 3T3-L1 adipocytes. Proc Natl Acad Sci USA 93: 5793-5796 (1996).
19. Macdougald OA, Hwang CS, Fan HY, Lane MD: Regulated expression of the obese gene-product (leptin) in white adipose-tissue and 3T3-L1 adipocytes. Proc Natl Acad Sci USA 92: 9034-9037 (1995).
20. Rentsch J, Chiesi M: Regulation of ob gene messenger-RNA levels in cultured adipocytes. FEBS Letters 379: 55-59 (1996).
21. Slieker LJ, Sloop KW, Surface PL, Kriauciunas A, Laquier F, Manetta J, Buevalleskey J, Stephens TW: Regulation of expression of ob messenger-RNA and protein by glucocorticoids and cAMP. J Biol Chem 271: 5301-5304 (1996).
22. Murakami T, Iida M, Shima K: Dexamethasone regulates obese expression in isolated rat adipocytes. Biochem Biophys Res Comm 214: 1260-1267 (1995).
23. Foley JE, Foley R, Gliemann J: Glucose-induced acceleration of deoxyglucose transport in rat. J Biol Chem 255: 9674-9677 (1980)
24. Mantzoros CS, Qu DQ, Frederich RC, Susulic VS, Lowell BB, Maratosflier E, Flier JS: Activation of beta(3) adrenergic-receptors suppresses leptin expression and mediates a leptin-independent inhibition of food-intake in mice. Diabetes 45: 909-914 (1996).
25. Gertner JM: Growth hormone actions on fat distribution and metabolism. Horm Res 38: 41-43 (1992).
26. Hotamisligil GS, Shargill NS, Spiegelmann BM: Adipose expression of tumor necrosis factor α: direct role in obesity-linked insulin resistance. Science 259: 87-91 (1993).
27. Kamai Y, Mikawa S, Endo K, Sakai H, Komano T: Regulation of insulin-like growth factor-I expression in mouse preadipocyte Ob1771 cells. J Biol Chem 271: 9883-9886 (1996).
28. Pomp D, Oberbauer AM, Murray JD: Development of obesity following inactivation of a growth hormone transgene in mice. Transgenic Res 5: 13-23 (1996).
29. Peter MA, Winterhalter KH, Boni-Schnetzler M, Froesch RE, Zapf J: Regulation of insulin-like growth factor I (IGF-I) and IGF-binding proteins by growth hormone in rat white adipose tissue. Endocrinology 133: 2624-2631 (1993).
30. Wabitsch M, Hauner H, Weinze E, Teller W: In vitro effects of growth hormone in adipose tissue. Acta Paediatr 406: 48-53 (1994).
31. Morin CL, Schlaepfer IR, Eckel RH: Tumor necrosis factor α eliminates binding of NF-Y and an octamer-binding protein to the lipoprotein lipase promoter in 3T3-L1 adipocytes. J Clin Invest 95: 1684-1689 (1995).
32. Petruschke TH, Hauner H: Tumor necrosis factor α prevents the differentiation of human adipocyte precursor cells and causes delipidation of newly developed fat cells. J Clin Endocrinol Metab 76: 742-747 (1993).
33. Vidal-Puig A, Jimenez-Linan M, Lowell BB, Hamann A, Erding H, Spiegelman B, Flier JS, Moller DE: Regulation of PPARγ gene expression by nutrition and obesity in rodents. J Clin Invest 97: 2553-2561 (1996).