Regulated expression of the diphtheria toxin A chain by a tumor-specific chimeric transcription factor results in selective toxicity for alveolar rhabdomyosarcoma cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 26, 1997, Pages 14701-14706

  Massuda, Edmond S ^a   Dunphy, Edward J ^a   Redman, Rebecca A ^a   Schreiber, Jennifer J ^a   Nauta, Lauren E ^b   Barr, Frederic G ^b   Maxwell, Ian H ^c   Cripe, Timothy P ^a,d  

^a University of Wisconsin Children's Hospital   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d University of Wisconsin Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; DIPHTHERIA TOXIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PAX 3 FKHR; TRANSCRIPTION FACTOR PAX 7 FKHR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; GENE TRANSFER; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; RHABDOMYOSARCOMA;

DIPHTHERIA TOXIN; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE THERAPY; GENE TRANSFER TECHNIQUES; HELA CELLS; HOMEODOMAIN PROTEINS; HUMANS; MUSCLE PROTEINS; NERVE TISSUE PROTEINS; PAX7 TRANSCRIPTION FACTOR; RECOMBINANT FUSION PROTEINS; RHABDOMYOSARCOMA, ALVEOLAR; TRANSCRIPTION FACTORS;

EID: 0031446784     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.26.14701     Document Type: Article

References (43)

1. Heyn, R., Haeberlen, V., Newton, W. A., Ragab, A. H., Raney, R. B., Tefft, M., Wharam, M., Ensign, L. G. & Maurer, H. M. (1993) J. Clin. Oncol. 11, 262-270.
2. Pappo, A. S., Shapiro, D. N., Crist, W. M. & Maurer, H. M. (1995) J. Clin. Oncol. 13, 2123-2139.
3. Barr, F. G., Galili, N., Holick, J., Biegel, J. A., Rovera, G. & Emanuel, B. S. (1993) Nat. Genet. 3, 113-117.
4. Davis, R., D'Cruz, C., Lovell, M., Biegel, J. & Barr, F. (1994) Cancer Res. 54, 2869-2872.
5. Galili, N., Davis, R. J., Fredericks, W. J., Mukhopadhyay, S., Rauscher, F. J., III, Emanuel, B. S., Rovera, G. & Barr, F. G. (1993) Nat. Genet. 5, 230-235.
6. Sublett, J., Jeon, I.-S. & Shapiro, D. (1995) Oncogene 11, 545-552.
7. Fredericks, W. J., Galili, N.. Mukhopadhyay, S., Rovera, G., Bennicelli, J., Barr, F. G. & Rauscher, F. J., III (1995) Mol. Cell. Biol. 15, 1522-1535.
8. Bennicelli, J., Edwards, R. & Barr, F. (1996) Proc. Natl. Acad. Sci. USA 93, 5455-5459.
9. Chalepakis, G., Goulding, M., Read, A., Strachan, T. & Gruss, P. (1994) Proc. Natl. Acad. Sci. USA 91, 3685-3689.
10. Strachan, T. & Read, A. P. (1994) Curr. Opin. Genet. Dev. 4, 427-438.
11. Stoykova, A. & Gruss, P. (1994) J. Neurosci. 14, 1395-1412.
12. Bernasconi, M., Remppis, A., Fredericks, W., Rauscher, F. J., III & Schafer, B. (1996) Proc. Natl. Acad. Sci. USA 93, 13164-13169.
13. Rabbitts, T. H. (1994) Nature (London) 372, 143-149.
14. Kmiec, E. B. (1996) Semin. Oncol. 23, 188-193.
15. Leopold, L. H., Shore, S. K. & Reddy, E. P. (1996) Leuk. Lymphoma 22, 365-373.
16. Kozu, T., Sueoka, E., Okabe, S., Sueoka, N., Komori, A. & Fujiki H. (1996) J. Cancer Res. Clin. Oncol. 122, 254-256.
17. Choo, Y., Sanchez-Garcia, I. & Klug, A. (1994) Nature (London) 372, 642-645.
18. Sandvig, K. & van Deurs, B. (1992) Exp. Cell Res. 200, 253-262
19. Kochi, S. K. & Collier, R. J. (1993) Exp. Cell Res. 208, 296-302.
20. Yamaizumi, M., Mekada, E., Uchida, T. & Okada, Y. (1978) Cell 15, 245-250.
21. Palmiter, R. D., Behringer, R. R., Quaife, C. J., Maxwell, F., Maxwell, I. H. & Brinster, R. L. (1987) Cell 50, 435-443, errata Cell 62, facing page 608.
22. Breitman, M. L., Clapoff, S., Rossant, J., Tsui, L. C., Glode, L. M., Maxwell, I. H. & Bernstein, A. (1987) Science 238, 1563-1565.
23. Breitman, M. L., Rombola, H., Maxwell, I. H., Klintworth, G. K. & Bernstein, A. (1990) Mol. Cell. Biol. 10, 474-479.
24. Behringer, R. R., Mathews, L. S., Palmiter, R. D. & Brinster, R. L. (1988) Genes Dev. 2, 453-461.
25. Maxwell, I. H., Maxwell, F. & Glode, L. M. (1986) Cancer Res. 46, 4660-4664.
26. Chalepakis, G., Fritsch, R., Fickenscher, H., Deutsch, U., Goulding, M. & Gruss, P. (1991) Cell 66, 873-884.
27. Maxwell, I. H., Harrison, G. S., Wood, W. M. & Maxwell, F. (1989) BioTechniques 7, 276-280.
28. Kozarsky, K. & Wilson, J. (1993) Curr. Opin. Genet. Dev. 3, 499-503.
29. Yoshimura, K., Rosenfeld, M., Seth, P. & Crystal, R. (1994) J. Biol. Chem. 268, 2300-2303.
30. Pool, M. & Arttamangkul, S. (1997) Cytometry 28, 36-41.
31. Seed, B. (1988) Gene 67, 271-277.
32. Kelly, K., Womer, R. & Barr, F. (1996) Cancer 78, 1320-1327.
33. Sikora, K. (1994) Gene Ther. 1, 149-151.
34. Kozmik, Z., Sure, U., Ruedi, D., Busslinger, M. & Aguzzi, A. (1995) Proc. Natl. Acad. Sci. USA 92, 5709-5713.
35. Weber-Hall, S., Anderson, J., McManus, A., Abe, S., Nojima, T., Pinkerton, R., Pritchard-Jones, K. & Shipley, J. (1996) Cancer Res. 56, 3220-3224.
36. Ogose, A., Motoyama, T., Hotta, T. & Watanabe, H. (1995) Virchows Archiv 426, 385-391.
37. Roth, J. & Cristiano, R. (1997) J. Natl. Cancer Inst. 89, 21-39.
38. Mesnil, M., Piccoli, C., Tiraby, G., Willecke, K. & Yamasaki, H. (1996) Proc. Natl. Acad. Sci. USA 93, 1831-1835.
39. Rill, D. R., Santana, V. M., Roberts, W. M., Nilson, T., Bowman, L. C., Krance, R. A., Heslop, H. E., Moen, R. C., Ihle, J. N. & Brenner, M. K. (1994) Blood 84, 380-383.
40. Maxwell, F., Maxwell, I. H. & Glode, L. M. (1987) Mol. Cell. Biol. 7, 1576-1579.
41. Kasahara, N., Dozy, A. & Kay, Y. (1994) Science 266, 1373-1376.
42. Barry, M., Dower, W. & Johnston, S. (1996) Nat. Med. 2, 299-305.
43. Chen, L., Chen, D., Yoshinobu, M., Dong, Y., Fine, H. & Kufe, D. (1995) J. Clin. Invest. 96, 2775-2782.