c-kit ligand stimulates tyrosine phosphorylation of the c-Cbl protein in human hematopoietic cells

Leukemia

Volumn 10, Issue 9, 1996, Pages 1436-1442

  Wisniewski, D ^a   Strife, A ^a   Clarkson, B ^a,b,c  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Memorial Hospital for Cancer and Allied Diseases   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

c Cbl; Grb2; Hematopoietic cells; Kit ligand; Tyrosine phosphorylation

Indexed keywords

HEMOPOIETIC GROWTH FACTOR; LIGAND; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE; STEM CELL FACTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTO ONCOGENE; SIGNAL TRANSDUCTION;

EID: 0029740513     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Dixon FJ (ed). Advances in Immunology, Vol 55. Academic Press: San Diego, CA, 1994.
2. Broxmeyer HE, Maze R, Miyazawa K, Carow C, Hendrie PC, Cooper S, Hangoc G, Vadhan-Raj S, Lu L. The kit receptor and its ligand, Steel factor, as regulators of hemopoiesis. Cancer Cells 1991; 3: 480-487 (review).
3. Metcalf D. Hematopoietic regulators: redundancy or subtlety? Blood 1993; 82: 3515-3523 (review).
4. Strife A, Perez A, Lambek C, Wisniewski D, Bruno S, Darzynkiewicz Z, Clarkson B. Characterization of lineage-negative blast subpopulations derived from normal and chronic myelogenous leukemia bone marrows and determination of their responsiveness to human c-kit ligand. Cancer Res 1993; 53: 401-409.
5. Brandt JE, Bhalla K, Huffman R. Effects of interleukin-3 and c-kit ligand on the survival of various classes of human hematopoietic progenitor cells. Blood 1994; 83: 1507-1514.
6. Cáceres-Cortés J, Rajotte D, Dumouchel J, Haddad P, Hoang T. Product of the Steel locus suppresses apoptosis in hemopoietic cells. Comparison with pathways activated by granulocyte-macrophage colony-stimulating factor. J Biol Chem 1994; 269: 12084-12091.
7. McNiece IL, Langley KE, Zsebo KM. Recombinant stem cell factor synergises with GM-CSF, G-CSF, IL-3, and Epo to stimulate human progenitor cells of the myeloid and erythroid lineages. Exp Hematol 1991; 19: 226-231.
8. - cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor. Blood 1991; 77: 2316-2321.
9. Migliaccio G, Migliaccio AR, Valinsky J, Langley K, Zsebo K, Visser JW, Adamson JW. Stem cell factor induces proliferation and differentiation of highly enriched murine hematopoietic cells. Proc Natl Acad Sci USA 1991; 88: 7420-7424.
10. Avraham H, Vannier E, Cowley S, Jiang SX, Chi S, Dinarello CA, Zsebo KM, Groopman JE. Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells. Blood 1992; 79: 365-371.
11. Qiu F, Ray P, Brown K, Barker PE, Jhanwar S, Ruddle FH, Besmer P. Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family - oncogenic activation of v-kit involves deletion of extracellular domain and C terminus. EMBO J 1988; 7: 1003-1011.
12. Hirayama F, Lyman SD, Clark SC, Ogawa M. The flt3 ligand supports proliferation of lymphohematopoietic progenitors and early B-lymphoid progenitors. Blood 1995; 85: 1762-1768.
13. Panayotou G, Waterfield MD. Assembly of signalling complexes by receptor tyrosine kinases. BioEssays 1993; 15: 171-177 (review).
14. BCR/ABL. J Biol Chem 1994; 269: 5016-5021.
15. Tauchi T, Boswell HS, Leibowitz D, Broxmeyer HE. Coupling between p210bcr-abl and She and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway. J Exp Med 1994; 179: 167-175.
16. vav, in human hemopoietic cells. J Biol Chem 1992; 267: 18021-18026.
17. BCR/ABL. EMBO J 1995; 14: 257-265.
18. Tang B, Mano H, Yi T, Ihle JN. Tec kinase associates with c-kit and is tyrosine phosphorylated and activated following stem cell factor binding. Mol Cell Biol 1994; 14: 8432-8437.
19. Yi T, Ihle JN. Association of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligand. Mol Cell Biol 1993; 13: 3350-3358.
20. Tauchi T, Feng G-S, Marshall MS, Shen R, Mantel C, Pawson T, Broxmeyer HE. The ubiquitously expressed Syp phosphatase interacts with c-kit and Grb2 in hematopoietic cells. J Biol Chem 1994; 269: 25206-25211.
21. Langdon WY, Hartley JW, Klinken SP, Ruscetti SK, Morse HC. v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas. Proc Natl Acad Sci USA 1989; 86: 1168-1172.
22. Mushinski JF, Goodnight JA, Rudikoff E, Morse HC III, Langdon WY. Expression of c-abl proto-oncogene is modulated during differentiation but not during induction of proliferation. Oncogene 1994; 9: 2489-2497.
23. Yoon CH, Lee J, Jongeward GD, Sternberg PW. Similarity of sli-1, a regulator of vulval development in C. elegans to the mammalian proto-oncogene c-cbl. Science 1995; 269: 1102-1105.
24. Meisner H, Conway BR, Hartley D, Czech MP. Interactions of Cbl with Grb2 and phosphatidylinositol 3′-kinase in activated Jurkat cells. Mol Cell Biol 1995; 15: 3571-3578.
25. Fukazawa T, Reedquist KA, Trub T, Soltoff S, Panchamoorthy G, Druker B, Cantley L, Shoelson SE, Band H. The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase. J Biol Chem 1995; 270: 19141-19150.
26. Cory GOC, Lovering RC, Hinshelwood S, MacCarthy-Morrogh L, Levinsky RJ, Kinnon C. The protein product of the c-cbl protoon-cogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase. J Exp Med 1995; 182: 611-615.
27. Tanaka S, Neff L, Baron R, Levy JB. Tyrosine phosphorylation and translocation of the c-Cbl protein after activation of tyrosine kinase signaling pathways. J Biol Chem 1995; 270: 14347-14351.
28. Galisteo ML, Dikic I, Batzer AG, Langdon WY, Schlessinger J. Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation. J Biol Chem 1995; 270: 20242-20245.
29. Bowtell DDL, Langdon WY. The protein product of the c-cbl oncogene rapidly complexes with the EGF receptor and is tyrosine phosphorylated following EGF stimulation. Oncogene 1995; 11: 1561-1567.
30. Meisner Y, Czech MP. Coupling of the proto-oncogene product c-Cbl to the epidermal growth factor receptor. J Biol Chem 1995; 270: 25332-25335.
31. Odai H, Sasaki K, Iwamatsu A, Hanazono Y, Tanaka T, Mitani K, Yazaki Y, Hirai H. The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells. J Biol Chem 1995; 270: 10800-10805.
32. Wang Y, Yeung Y-G, Langdon WY, Stanley ER. c-Cbl is transiently tyrosine-phosphorylated, ubiquitinated, and membrane-targeted following CSF-1 stimulation of macrophages. J Biol Chem 1996; 271: 17-20.
33. Andoniou CEA, Thien CBF, Langdon WY. Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene. EMBO J 1994; 13: 4515-4523.
34. c-Cbl. Exp Hematol 1996; 24: 310-313.
35. BCR/ABI to the phosphatidylinositol-3′ kinase pathway. Oncogene 1996; 12: 839-846.
36. de Jong R, ten Hoeve J, Heisterkamp N, Groffen J. Crkl is complexed with tyrosine-phosphorylated Cbl in Ph-positive leukemia. J Biol Chem 1995; 270: 21468-21471.
37. Avanzi GC, Lista P, Giovinazzo B, Miniero R, Saglio G, Benetton G, Coda R, Cattoretti G, Pegoraro L. Selective growth response to IL-3 of a human leukaemic cell line with megakaryoblastic features. Br J Haematol 1988; 69: 359-366.
38. Santoli D, Yang Y-C, Clark SC, Kreider BL, Caracciolo D, Rovera G. Synergistic and antagonistic effects of recombinant human interleukin (IL) 3, IL-1α, granulocyte and macrophage colony-stimulating factors (G-CSF and M-CSF) on the growth of GM-CSF-dependent leukemic cell lines. J Immunol 1987; 139: 3348-3354.
39. Kitamura T, Tange T, Terasawa T, Chiba S, Kuwaki T, Miyagawa K, Piao Y-F, Miyazono K, Urabe A, Takaku F. Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin. J Cell Physiol 1989; 140: 323-334.
40. Wisniewski D, Strife A, Berman E, Clarkson B. C-kit ligand stimulates tyrosine phosphorylation of a similar pattern of phosphotyrosyl proteins in primary primitive normal hematopoietic progenitors that are constitutively phosphorylated in comparable primitive progenitors in chronic phase chronic myelogenous leukemia. Leukemia 1996; 10: 229-237.
41. Hendrie PC, Miyazawa K, Yang Y-C, Langefeld CD, Broxmeyer HE. Mast cell growth factor (c-kit ligand) enhances cytokine stimulation of proliferation of human factor dependent cell line, MO7e. Exp Hematol 1991; 19: 1031-1037.
42. Lowenstein EJ, Daly RJ, Batzer AG, Li W, Margolis B, Lammers R, Ullrich A, Skolnik EY, Bar-Sagi D, Schlessinger J. The SH2 and SH3 domain-containing protein GRB-2 links receptor tyrosine kinases to ras signaling. Cell 1992; 70: 431-442.
43. Buday L, Downward J. Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adaptor protein, and Sos nucleotide exchange factor. Cell 1993; 73: 611-620.
44. Rozakis-Adcock M, Fernley R, Wade J, Pawson T, Bowtell D. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1. Nature 1993; 363: 83-85.
45. Chardin P, Cussac D, Maignan S, Ducruix A. The Grb2 adaptor. FEBS Lett 1995; 369: 47-51.
46. Bar-Sagi D, Rotin D, Batzer A, Mandiyan V, Schlessinger J. SH3 domains direct cellular localization of signaling molecules. Cell 1993; 74: 83-91.
47. Matuoka K, Shibasaki F, Shibata M, Takenawa T. Ash/Grb2, and SH2/SH3-containing protein, couples to signaling for mitogenesis and cytoskeletal reorganization by EGDF and PDGF. EMBO J 1993; 12: 3467-3473.
48. Donovan J, Wange R, Langdon W, Samelson L. The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the T cell antigen receptor. J Biol Chem 1994; 169: 22921-22924.
49. Rivero-Lezcano O, Sameshima J, Marcilla A, Robbins K. Physical association between src homology 3 elements and the protein product of the c-cbl proto-oncogene. J Biol Chem 1994; 269: 17363-17366.
50. Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J. Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. Nature (Lond) 1993; 363: 85-88.
51. Miyazawa K, Hendrie PC, Mantel C, Wood K, Ashman LK, Broxmeyer HE. Comparative analysis of signaling pathways between mast cell growth factor (c-kit ligand) and granulocyte-macrophage colony-stimulating factor in a human factor-dependent myeloid cell line involves phosphorylation of Raf-1, GTPase-activating protein and mitogen-activated protein kinase. Exp Hematol 1991; 19: 1110-1123.
52. cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase. J Biol Chem 1996; 271: 3187-3194.