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Volumn 57, Issue 3, 1997, Pages 549-554

Telomerase activity is associated with cell cycle deregulation in human breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN D1; CYCLIN E; KI 67 ANTIGEN; PROTEIN P16; RETINOBLASTOMA PROTEIN; TELOMERASE;

EID: 0031050924     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (84)

References (54)
  • 1
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley, C. B., Futcher, A. B., and Greider, C. W. Telomeres shorten during ageing of human fibroblasts. Nature (Lond.), 345: 458-460, 1990.
    • (1990) Nature (Lond.) , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 3
    • 0029145379 scopus 로고
    • Evidence for a critical telomere length in senescent human fibroblasts
    • Allsopp, R. C., and Harley, C. B. Evidence for a critical telomere length in senescent human fibroblasts. Exp. Cell Res., 219: 130-136, 1995.
    • (1995) Exp. Cell Res. , vol.219 , pp. 130-136
    • Allsopp, R.C.1    Harley, C.B.2
  • 4
    • 0029127226 scopus 로고
    • Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: A model for senescence?
    • von Zglinicki, T., Saretzki, G., Döcke, W., and Lotze, C. Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence? Exp. Cell Res., 220: 186-193, 1995.
    • (1995) Exp. Cell Res. , vol.220 , pp. 186-193
    • Von Zglinicki, T.1    Saretzki, G.2    Döcke, W.3    Lotze, C.4
  • 5
    • 0029924534 scopus 로고    scopus 로고
    • From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: The telomere loss/DNA damage model of cell aging
    • Vaziri, H., and Benchimol, S. From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: the telomere loss/DNA damage model of cell aging. Exp. Gerontol., 31: 295-301, 1996.
    • (1996) Exp. Gerontol. , vol.31 , pp. 295-301
    • Vaziri, H.1    Benchimol, S.2
  • 6
    • 0028261160 scopus 로고
    • Escape from senescence in human diploid fibroblasts induced directly by mutant p53
    • Bond, J. A., Wyllie, F. S. and Wynford-Thomas, D. Escape from senescence in human diploid fibroblasts induced directly by mutant p53. Oncogene, 9: 1885-1889, 1994.
    • (1994) Oncogene , vol.9 , pp. 1885-1889
    • Bond, J.A.1    Wyllie, F.S.2    Wynford-Thomas, D.3
  • 8
    • 1842346897 scopus 로고
    • Both Rb and p53 are potential regulators of human cellular senescence
    • M. L. Brandi and R. White (eds.), New York: Raven Press
    • Shay, J. W., and Wright, W. E. Both Rb and p53 are potential regulators of human cellular senescence. In: M. L. Brandi and R. White (eds.), Hereditary Tumors, pp. 173-182. New York: Raven Press, 1991.
    • (1991) Hereditary Tumors , pp. 173-182
    • Shay, J.W.1    Wright, W.E.2
  • 9
    • 0025729836 scopus 로고
    • Defining the molecular mechanisms of human cell immortalization
    • Shay, J. W., Wright, W. E., and Werbin, H. Defining the molecular mechanisms of human cell immortalization. Biochem. Biophys. Acta, 1072: 1-7, 1991.
    • (1991) Biochem. Biophys. Acta , vol.1072 , pp. 1-7
    • Shay, J.W.1    Wright, W.E.2    Werbin, H.3
  • 10
    • 0019305047 scopus 로고
    • Limited lifespan in somatic cell hybrids and cybrids
    • Bunn, C. L., and Tarrant, G. M. Limited lifespan in somatic cell hybrids and cybrids. Exp. Cell Res., 127: 385-396, 1980.
    • (1980) Exp. Cell Res. , vol.127 , pp. 385-396
    • Bunn, C.L.1    Tarrant, G.M.2
  • 11
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in tetrahymena extracts
    • Greider, C. W., and Blackburn, E. H. Identification of a specific telomere terminal transferase activity in tetrahymena extracts. Cell, 43: 405-413, 1985.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 12
    • 0024325562 scopus 로고
    • The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
    • Morin, G. B. The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell, 59: 521-529, 1989.
    • (1989) Cell , vol.59 , pp. 521-529
    • Morin, G.B.1
  • 14
    • 0028007237 scopus 로고
    • Telomere dynamics in an immortal human cell line
    • Murnane, J. P., Sabatier, L., Marder, B. A., and Morgan, W. F. Telomere dynamics in an immortal human cell line. EMBO J., 13: 4953-4962, 1994.
    • (1994) EMBO J. , vol.13 , pp. 4953-4962
    • Murnane, J.P.1    Sabatier, L.2    Marder, B.A.3    Morgan, W.F.4
  • 15
    • 0029162563 scopus 로고
    • Telomere elongation in immortal human cells without detectable telomerase activity
    • Bryan, M. T., Englezou, A., Gupta, J., Bacchetti, S., and Reddel, R. R. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J., 14: 4240-4248, 1995.
    • (1995) EMBO J. , vol.14 , pp. 4240-4248
    • Bryan, M.T.1    Englezou, A.2    Gupta, J.3    Bacchetti, S.4    Reddel, R.R.5
  • 16
    • 0029655485 scopus 로고    scopus 로고
    • Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines
    • Strahl, C., and Blackburn, E. H. Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines. Mol. Cell. Biol., 16: 53-65, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 53-65
    • Strahl, C.1    Blackburn, E.H.2
  • 18
    • 0027956728 scopus 로고
    • Telomerase activity in vitro in human malignant hematopoietic cells
    • Nilsson, P., Mehle, C., Remes, K., and Roos, G. Telomerase activity in vitro in human malignant hematopoietic cells. Oncogene, 9: 3043-3048, 1994.
    • (1994) Oncogene , vol.9 , pp. 3043-3048
    • Nilsson, P.1    Mehle, C.2    Remes, K.3    Roos, G.4
  • 19
    • 0029114679 scopus 로고
    • Telomeres and telomerase in human cancer
    • Bacchetti, S., and Counter, C. M. Telomeres and telomerase in human cancer. Int. J. Oncol., 7: 423-432, 1995.
    • (1995) Int. J. Oncol. , vol.7 , pp. 423-432
    • Bacchetti, S.1    Counter, C.M.2
  • 22
    • 0029019717 scopus 로고
    • Telomerase activity in human liver tissues: Comparison between chronic liver disease and hepatocellular carcinomas
    • Tahara, H., Nakanishi, T., Kitamoto, M., Nakashio, R., Shay, J. W., Tahara, E., Kajiyama, G., and Ide, T. Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas. Cancer Res., 55: 2734-2736, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 2734-2736
    • Tahara, H.1    Nakanishi, T.2    Kitamoto, M.3    Nakashio, R.4    Shay, J.W.5    Tahara, E.6    Kajiyama, G.7    Ide, T.8
  • 26
    • 0029937268 scopus 로고    scopus 로고
    • Telomerase activation in normal B lymphocytes and non-Hodgkin's lymphomas
    • Norrback, K-F., Dahlenborg, K., Carlsson, R., and Roos, G. Telomerase activation in normal B lymphocytes and non-Hodgkin's lymphomas. Blood, 88: 222-229, 1996.
    • (1996) Blood , vol.88 , pp. 222-229
    • Norrback, K.-F.1    Dahlenborg, K.2    Carlsson, R.3    Roos, G.4
  • 28
    • 0029973653 scopus 로고    scopus 로고
    • Regulation of telomerase activity in immortal cell lines
    • Holt, S. E., Wright, W. E., and Shay, J. W. Regulation of telomerase activity in immortal cell lines. Mol. Cell Biol., 16: 2932-2939, 1996.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 2932-2939
    • Holt, S.E.1    Wright, W.E.2    Shay, J.W.3
  • 29
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R. A. The retinoblastoma protein and cell cycle control. Cell, 81: 323-330, 1995.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 30
    • 0029286242 scopus 로고
    • Cyclins, CDKs and cancer
    • Pines, J. Cyclins, CDKs and cancer. Semin. Cancer Biol., 6: 63-72, 1995.
    • (1995) Semin. Cancer Biol. , vol.6 , pp. 63-72
    • Pines, J.1
  • 32
    • 0026057931 scopus 로고
    • Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis
    • Borg, A., Sigurdsson, H., Clark, G. M., Freno, M., Fuqua, S. A. W., Olsson, H., Killander, D., and McGurie, W. L. Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis. Br. J. Cancer. 63: 136-142, 1991.
    • (1991) Br. J. Cancer. , vol.63 , pp. 136-142
    • Borg, A.1    Sigurdsson, H.2    Clark, G.M.3    Freno, M.4    Fuqua, S.A.W.5    Olsson, H.6    Killander, D.7    McGurie, W.L.8
  • 35
    • 0029161567 scopus 로고
    • Deregulation of cyclin E in breast cancer
    • Keyomarsi, K., Conte, D., Jr., Toyofuku, W., and Fox, P. Deregulation of cyclin E in breast cancer. Oncogene, 11: 941-950, 1995.
    • (1995) Oncogene , vol.11 , pp. 941-950
    • Keyomarsi, K.1    Conte Jr., D.2    Toyofuku, W.3    Fox, P.4
  • 36
    • 0029758105 scopus 로고    scopus 로고
    • Cyclin E overexpression, a negative prognostic factor in breast cancer with strong correlation to oestrogen receptor status
    • Nielsen, N. H., Amerlöv, C., Emdin, S. O., and Landberg, G. Cyclin E overexpression, a negative prognostic factor in breast cancer with strong correlation to oestrogen receptor status. Br. J. Cancer, 74: 874-880, 1996.
    • (1996) Br. J. Cancer , vol.74 , pp. 874-880
    • Nielsen, N.H.1    Amerlöv, C.2    Emdin, S.O.3    Landberg, G.4
  • 37
    • 0028180384 scopus 로고
    • Inducible . acceleration of G1 progression through tetracycline-regulated expression of human cyclin E
    • Wimmel, A., Lucibello, F. C., Sewing, A., Adolphs, S., and Müller, R. Inducible . acceleration of G1 progression through tetracycline-regulated expression of human cyclin E. Oncogene, 9: 995-997, 1994.
    • (1994) Oncogene , vol.9 , pp. 995-997
    • Wimmel, A.1    Lucibello, F.C.2    Sewing, A.3    Adolphs, S.4    Müller, R.5
  • 38
    • 0028909645 scopus 로고
    • Human cyclin E, a nuclear protein essential for the G1- to S-phase transition
    • Ohtsubo, M., Theodoras, A. M., Schumacher, J., Roberts, J. M., and Pagano, M. Human cyclin E, a nuclear protein essential for the G1- to S-phase transition. Mol. Cell. Biol., 75: 2612-2624, 1995.
    • (1995) Mol. Cell. Biol. , vol.75 , pp. 2612-2624
    • Ohtsubo, M.1    Theodoras, A.M.2    Schumacher, J.3    Roberts, J.M.4    Pagano, M.5
  • 39
    • 0028913568 scopus 로고
    • Alterations in telomeric repeat length in lung cancer are associated with loss of heterozygosity in p53 and Rb
    • Hiyama, K., Ishioka, S., Shirotani, Y., Inai, K., Hiyama, E., Murakami, I., Isobe, T., Inamizu, T., and Yamakido, M. Alterations in telomeric repeat length in lung cancer are associated with loss of heterozygosity in p53 and Rb. Oncogene, 10: 937-944, 1995.
    • (1995) Oncogene , vol.10 , pp. 937-944
    • Hiyama, K.1    Ishioka, S.2    Shirotani, Y.3    Inai, K.4    Hiyama, E.5    Murakami, I.6    Isobe, T.7    Inamizu, T.8    Yamakido, M.9
  • 42
    • 0344252789 scopus 로고
    • Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP)
    • Piatyszek, M. A., Kim, N. W., Weinrich, S. L., Hiyama, K., Hiyama, E., Wright, W. E., and Shay, J. W. Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP). Methods Cell Sci., 17: 1-5, 1995.
    • (1995) Methods Cell Sci. , vol.17 , pp. 1-5
    • Piatyszek, M.A.1    Kim, N.W.2    Weinrich, S.L.3    Hiyama, K.4    Hiyama, E.5    Wright, W.E.6    Shay, J.W.7
  • 43
    • 0029023065 scopus 로고
    • Modifications of a telomeric repeat amplification protocol (TRAP) results in increased reliability, linearity and sensitivity
    • Wright, W. E., Shay, J. W., and Piatyszek, M. A. Modifications of a telomeric repeat amplification protocol (TRAP) results in increased reliability, linearity and sensitivity. Nucleic Acids Res., 23: 3794-3795, 1995.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 3794-3795
    • Wright, W.E.1    Shay, J.W.2    Piatyszek, M.A.3
  • 45
    • 0027412111 scopus 로고
    • Toward a molecular understanding of human breast cancer: A hypothesis
    • Shay, J. W., Wright, W. E., and Werbin, H. Toward a molecular understanding of human breast cancer: a hypothesis. Breast Cancer Res. Treat., 25: 83-94, 1993.
    • (1993) Breast Cancer Res. Treat. , vol.25 , pp. 83-94
    • Shay, J.W.1    Wright, W.E.2    Werbin, H.3
  • 47
    • 0028951667 scopus 로고
    • Expression of retinoblastoma gene protein (Rb) in breast cancer as related to established prognostic factors and survival
    • Pietiläinen, T., Lipponen, P., Aaltomaa, S., Eskelinen, M., Kosma, V. M., and Syrjänen, K. Expression of retinoblastoma gene protein (Rb) in breast cancer as related to established prognostic factors and survival. Eur. J. Cancer, 31: 329-333, 1995.
    • (1995) Eur. J. Cancer , vol.31 , pp. 329-333
    • Pietiläinen, T.1    Lipponen, P.2    Aaltomaa, S.3    Eskelinen, M.4    Kosma, V.M.5    Syrjänen, K.6
  • 50
    • 1842311449 scopus 로고    scopus 로고
    • Deregulation of cyclin E and D1 in breast cancer is associated with inactivation of the retinoblastoma protein
    • in press
    • Nielsen, N. H., Emdin, S. O., Cajander, J., and Landberg, G. Deregulation of cyclin E and D1 in breast cancer is associated with inactivation of the retinoblastoma protein. Oncogene, in press, 1996.
    • (1996) Oncogene
    • Nielsen, N.H.1    Emdin, S.O.2    Cajander, J.3    Landberg, G.4
  • 51
    • 0027976222 scopus 로고
    • Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: Link between cell cycle control and malignant transformation
    • Lovec, H., Sewing, A., Lucibello, F. C., Müller, H., and Möröy, T. Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: link between cell cycle control and malignant transformation. Oncogene, 9: 323-326, 1994.
    • (1994) Oncogene , vol.9 , pp. 323-326
    • Lovec, H.1    Sewing, A.2    Lucibello, F.C.3    Müller, H.4    Möröy, T.5
  • 52
    • 0028139463 scopus 로고
    • Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
    • Wang, J. Y. J., Knudsen, E. S., and Welch, P. J. Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Adv. Cancer Res., 64: 25-85, 1994.
    • (1994) Adv. Cancer Res. , vol.64 , pp. 25-85
    • Wang, J.Y.J.1    Knudsen, E.S.2    Welch, P.J.3
  • 53
    • 0029883680 scopus 로고    scopus 로고
    • A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer
    • Michalides, R., Hageman, P., van Tineren, H., Houben, L., Wientjens, E., Klompmarker, R., and Peterse, J. A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer. Br. J. Cancer, 73: 728-734, 1996.
    • (1996) Br. J. Cancer , vol.73 , pp. 728-734
    • Michalides, R.1    Hageman, P.2    Van Tineren, H.3    Houben, L.4    Wientjens, E.5    Klompmarker, R.6    Peterse, J.7
  • 54
    • 0027193034 scopus 로고
    • Cyclin-dependent regulation of G1 in mammalian fibroblasts
    • Ohtsubo, M., and Roberts, J. M. Cyclin-dependent regulation of G1 in mammalian fibroblasts. Science (Washington DC), 26: 1908-1912, 1993.
    • (1993) Science (Washington DC) , vol.26 , pp. 1908-1912
    • Ohtsubo, M.1    Roberts, J.M.2


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