메뉴 건너뛰기




Volumn 10, Issue 1, 1997, Pages 5-21

Genetic aberrations in squamous cell carcinoma of the head and neck (SCCHN), with reference to oral carcinoma (Review)

Author keywords

Head and neck cancer; Oral carcinoma; Squamous cell carcinoma

Indexed keywords

GENE EXPRESSION; HEAD AND NECK CANCER; HUMAN; ONCOGENE; PRIORITY JOURNAL; REVIEW; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE;

EID: 0031017764     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.10.1.5     Document Type: Review
Times cited : (29)

References (324)
  • 1
    • 0022150834 scopus 로고
    • Advanced methods in the evaluation of premalignant lesions and carcinomas of the oral mucosa
    • Burkhardt A: Advanced methods in the evaluation of premalignant lesions and carcinomas of the oral mucosa. J Oral Pathol 14: 751-778, 1985.
    • (1985) J Oral Pathol , vol.14 , pp. 751-778
    • Burkhardt, A.1
  • 2
    • 0026636412 scopus 로고
    • Oncogenes and tumour-suppressor genes in squamous cell carcinoma of the head and neck
    • Field JK: Oncogenes and tumour-suppressor genes in squamous cell carcinoma of the head and neck. Eur J Cancer Oral Oncol 28B: 67-76, 1992.
    • (1992) Eur J Cancer Oral Oncol , vol.28 B , pp. 67-76
    • Field, J.K.1
  • 3
    • 10144260096 scopus 로고
    • Oncogenes and tumour suppressor genes as prognostic indicators in the development of human tumours
    • Pusztai L, Lewis CE and Yap E (eds). Oxford University Press, Oxford
    • Field JK and Spandidos DA: Oncogenes and tumour suppressor genes as prognostic indicators in the development of human tumours. In: Regulation and Proliferation of Neoplastic Cells. Pusztai L, Lewis CE and Yap E (eds). Vol. 1. Oxford University Press, Oxford, pp59-78, 1995.
    • (1995) Regulation and Proliferation of Neoplastic Cells , vol.1 , pp. 59-78
    • Field, J.K.1    Spandidos, D.A.2
  • 4
    • 0026800767 scopus 로고
    • Genetic alterations in head and neck cancer
    • Somers KD and Schechter GL: Genetic alterations in head and neck cancer. Otolaryngol Clin N Amer 25: 1065-1071, 1992.
    • (1992) Otolaryngol Clin N Amer , vol.25 , pp. 1065-1071
    • Somers, K.D.1    Schechter, G.L.2
  • 5
    • 0027329996 scopus 로고
    • Oncogenes, tumour suppressors and viruses in oral squamous carcinoma
    • Scully C: Oncogenes, tumour suppressors and viruses in oral squamous carcinoma. J Oral Pathol Med 22: 337-347, 1993.
    • (1993) J Oral Pathol Med , vol.22 , pp. 337-347
    • Scully, C.1
  • 6
    • 0029366565 scopus 로고
    • Review article: The role of oncogenesis, tumour suppressor genes and growth factors in oral squamous cell carcinoma: a case of apoptosis versus proliferation
    • Sugerman PB, Joseph BK and Savage NW: Review article: the role of oncogenesis, tumour suppressor genes and growth factors in oral squamous cell carcinoma: a case of apoptosis versus proliferation. Oral Diseases 1: 172-188, 1995.
    • (1995) Oral Diseases , vol.1 , pp. 172-188
    • Sugerman, P.B.1    Joseph, B.K.2    Savage, N.W.3
  • 7
    • 84930300557 scopus 로고
    • Potentially malignant lesions and conditions of the mouth and oropharynx: Natural history - Cellular and molecular markers of risk
    • Johnson NW, Ranasinghe AW and Warnakulasuriya KAAS: Potentially malignant lesions and conditions of the mouth and oropharynx: natural history - cellular and molecular markers of risk. Eur J Cancer Prevent 2 (Suppl 2): 31-51, 1993.
    • (1993) Eur J Cancer Prevent , vol.2 , Issue.2 SUPPL. , pp. 31-51
    • Johnson, N.W.1    Ranasinghe, A.W.2    Warnakulasuriya, K.A.A.S.3
  • 8
    • 0025294748 scopus 로고
    • Chromosome abnormalities in squamous cell carcinoma of the human oral cavity
    • Ravindran T, Vijayakumar T, Sudha L, et al: Chromosome abnormalities in squamous cell carcinoma of the human oral cavity. Neoplasma 37:191-197, 1990.
    • (1990) Neoplasma , vol.37 , pp. 191-197
    • Ravindran, T.1    Vijayakumar, T.2    Sudha, L.3
  • 10
    • 0026795877 scopus 로고
    • Cytogenetics in head and neck cancer
    • Cowan JM: Cytogenetics in head and neck cancer. Mol Biol Genet 25: 1073-1087, 1992.
    • (1992) Mol Biol Genet , vol.25 , pp. 1073-1087
    • Cowan, J.M.1
  • 11
    • 0028100027 scopus 로고
    • Allelic loss at chromosomes 3p, 8p, 13q, and 17p associated with poor prognosis in head and neck cancer
    • Li XH, Lee NK, Ye YW, Waber PG, Schweitzer C, Cheng QC and Nisen PD: Allelic loss at chromosomes 3p, 8p, 13q, and 17p associated with poor prognosis in head and neck cancer. J Natl Cancer Inst 86: 1524-1529, 1994.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1524-1529
    • Li, X.H.1    Lee, N.K.2    Ye, Y.W.3    Waber, P.G.4    Schweitzer, C.5    Cheng, Q.C.6    Nisen, P.D.7
  • 12
    • 0028155340 scopus 로고
    • Allelotype of squamous carcinoma of the head and neck using microsatellite
    • Ah-See KW, Cooke TG, Pickford IR, Soutar D and Balmain A: Allelotype of squamous carcinoma of the head and neck using microsatellite. Cancer Res 54: 1617-1621, 1994.
    • (1994) Cancer Res , vol.54 , pp. 1617-1621
    • Ah-See, K.W.1    Cooke, T.G.2    Pickford, I.R.3    Soutar, D.4    Balmain, A.5
  • 15
    • 0028067519 scopus 로고
    • Cancer genetics
    • Bodmer WF: Cancer genetics. Br Med Bull 50: 517-526, 1994.
    • (1994) Br Med Bull , vol.50 , pp. 517-526
    • Bodmer, W.F.1
  • 19
    • 0027302839 scopus 로고
    • Recurrent Cytogenetic abnormalities in squamous cell carcinoma in South African Indians: A retrospective study
    • van Dyke DL, Worsham MJ, Benninger MS, et al: Recurrent Cytogenetic abnormalities in squamous cell carcinoma in South African Indians: a retrospective study. S Afr Med J 83: 425-429, 1993.
    • (1993) S Afr Med J , vol.83 , pp. 425-429
    • Van Dyke, D.L.1    Worsham, M.J.2    Benninger, M.S.3
  • 21
    • 0025740210 scopus 로고
    • Cytogenetic surveillance of tobacco-areca nut (mava) chewers, including patients with oral cancers and premalignant conditions
    • Adhvaryu SG, Dave BJ and Trivedi AH: Cytogenetic surveillance of tobacco-areca nut (mava) chewers, including patients with oral cancers and premalignant conditions. Mutat Res 261: 41-49, 1991.
    • (1991) Mutat Res , vol.261 , pp. 41-49
    • Adhvaryu, S.G.1    Dave, B.J.2    Trivedi, A.H.3
  • 22
    • 0023475508 scopus 로고
    • Increased fragile sites and sister chromatid exchanges in bone marrow and peripheral blood of young cigarette smokers
    • Kao-Shan CS, Fine RL, Whang-Peng J, Lee EC and Chabner BA: Increased fragile sites and sister chromatid exchanges in bone marrow and peripheral blood of young cigarette smokers. Cancer Res 47: 6278-6282, 1987.
    • (1987) Cancer Res , vol.47 , pp. 6278-6282
    • Kao-Shan, C.S.1    Fine, R.L.2    Whang-Peng, J.3    Lee, E.C.4    Chabner, B.A.5
  • 23
    • 0029922149 scopus 로고    scopus 로고
    • Genetic susceptibility to head and neck squamous cell carcinoma
    • Cloos J, Spitz MR, Schants SP, et al: Genetic susceptibility to head and neck squamous cell carcinoma. J Natl Cancer Inst 88: 530-535, 1996.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 530-535
    • Cloos, J.1    Spitz, M.R.2    Schants, S.P.3
  • 24
    • 0023218109 scopus 로고
    • Immunoglobin allotypes in head and neck cancer patients with multiple primary cancers
    • De Vries N, De Lange G, Drexhage HA and Snow GB: Immunoglobin allotypes in head and neck cancer patients with multiple primary cancers. Acta Oto-laryngol 104: 187-191, 1987.
    • (1987) Acta Oto-laryngol , vol.104 , pp. 187-191
    • De Vries, N.1    De Lange, G.2    Drexhage, H.A.3    Snow, G.B.4
  • 25
    • 0023626530 scopus 로고
    • HLA antigens and immunoglobulin allotypes in head and neck cancer patients with and without multiple primary tumors
    • De Vries N, De Waal LP, De Lange G, Drexhage HA and Snow GB: HLA antigens and immunoglobulin allotypes in head and neck cancer patients with and without multiple primary tumors. Cancer 60: 957-961, 1987.
    • (1987) Cancer , vol.60 , pp. 957-961
    • De Vries, N.1    De Waal, L.P.2    De Lange, G.3    Drexhage, H.A.4    Snow, G.B.5
  • 26
    • 0024348361 scopus 로고
    • Chromosome sensitivity to bleomycin-induced mutagenesis, an independent risk factor for upper aerodigestive tract cancers
    • Spitz MR, Fueger JJ, Beddingfield NA, Annegers JF, Hsu TC, Newell GR and Schantz SP: Chromosome sensitivity to bleomycin-induced mutagenesis, an independent risk factor for upper aerodigestive tract cancers. Cancer Res 49: 4626-4628, 1989.
    • (1989) Cancer Res , vol.49 , pp. 4626-4628
    • Spitz, M.R.1    Fueger, J.J.2    Beddingfield, N.A.3    Annegers, J.F.4    Hsu, T.C.5    Newell, G.R.6    Schantz, S.P.7
  • 28
    • 0025650896 scopus 로고
    • Mutagen sensitivity in patients with head and neck cancers: A biologic marker for risk of multiple primary malignancies
    • Schantz SP, Spitz MR and Hsu TC: Mutagen sensitivity in patients with head and neck cancers: a biologic marker for risk of multiple primary malignancies. J Natl Cancer Inst 82: 1773-1775, 1990.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 1773-1775
    • Schantz, S.P.1    Spitz, M.R.2    Hsu, T.C.3
  • 29
    • 0028266469 scopus 로고
    • Increased mutagen sensitivity in head and neck squamous cell carcinoma patients, particularly those with multiple primary tumors
    • Cloos J, Braakhuis BJM, Steen I, Copper MP, De Vries N, Nauta JJP and Snow GB: Increased mutagen sensitivity in head and neck squamous cell carcinoma patients, particularly those with multiple primary tumors. Int J Cancer 56: 816-819, 1994.
    • (1994) Int J Cancer , vol.56 , pp. 816-819
    • Cloos, J.1    Braakhuis, B.J.M.2    Steen, I.3    Copper, M.P.4    De Vries, N.5    Nauta, J.J.P.6    Snow, G.B.7
  • 30
    • 0027567218 scopus 로고
    • Association between family history of cancer and mutagen sensitivity in upper aerodigestive tract cancer patients
    • Bondy ML, Spitz MR, Halibi S, et al: Association between family history of cancer and mutagen sensitivity in upper aerodigestive tract cancer patients. Cancer Epidem Biomarker Prev 2: 103-106, 1991.
    • (1991) Cancer Epidem Biomarker Prev , vol.2 , pp. 103-106
    • Bondy, M.L.1    Spitz, M.R.2    Halibi, S.3
  • 32
    • 0027140815 scopus 로고
    • Monitoring of smokeless tobacco consumers using cytogenetic endpoints
    • Trivedi AH, Bhavana JD and Adhvaryu SG: Monitoring of smokeless tobacco consumers using cytogenetic endpoints. Anticancer Res 13: 2245-2250, 1993.
    • (1993) Anticancer Res , vol.13 , pp. 2245-2250
    • Trivedi, A.H.1    Bhavana, J.D.2    Adhvaryu, S.G.3
  • 34
    • 0027998601 scopus 로고
    • Sister chromatid exchange frequencies in lymphocytes of oral cancer patients seem to be influenced by drinking habits
    • Popp W, Wolf R, Vahrenholz C, Radtke J, Schell C, Kraus R, Brauksiepe G and Norpoth K: Sister chromatid exchange frequencies in lymphocytes of oral cancer patients seem to be influenced by drinking habits. Carcinogenesis 15: 1603-1607, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 1603-1607
    • Popp, W.1    Wolf, R.2    Vahrenholz, C.3    Radtke, J.4    Schell, C.5    Kraus, R.6    Brauksiepe, G.7    Norpoth, K.8
  • 35
    • 0030065735 scopus 로고    scopus 로고
    • Centromeric breakage as a major cause of cytogenetic abnormalities in, oral squamous cell carcinoma
    • Hermsen MAJA, Joenje H, Arwert F, et al: Centromeric breakage as a major cause of cytogenetic abnormalities in, oral squamous cell carcinoma. Genes Chromosom Cancer 15: 1-9, 1996.
    • (1996) Genes Chromosom Cancer , vol.15 , pp. 1-9
    • Hermsen, M.A.J.A.1    Joenje, H.2    Arwert, F.3
  • 36
    • 0027425894 scopus 로고
    • Chromosome abnormalities in oral squamous cell carcinomas
    • Jin Y and Mertens F: Chromosome abnormalities in oral squamous cell carcinomas. Oral Oncol Eur J Cancer 29B: 257-263, 1993.
    • (1993) Oral Oncol Eur J Cancer , vol.29 B , pp. 257-263
    • Jin, Y.1    Mertens, F.2
  • 38
    • 0025093299 scopus 로고
    • Frequent arrangement of chromsomal bands 1p22 and 11q13 in squamous cell carcinomas of the head and neck
    • Jin Y, Higashi K, Mandahl N, et al: Frequent arrangement of chromsomal bands 1p22 and 11q13 in squamous cell carcinomas of the head and neck. Genes Chromosom Cancer 2: 198-204, 1990.
    • (1990) Genes Chromosom Cancer , vol.2 , pp. 198-204
    • Jin, Y.1    Higashi, K.2    Mandahl, N.3
  • 39
    • 0027238628 scopus 로고
    • Chromosome abnormalities in eighty-three head and neck squamous cell carcinomas: Influence of culture conditions on karyotypic pattern
    • Jin Y, Mertens F, Mandahl N, Heim S, Olegard C, Wennerberg J, Bjorklund A and Mitelman F: Chromosome abnormalities in eighty-three head and neck squamous cell carcinomas: influence of culture conditions on karyotypic pattern. Cancer Res 53: 2140-2146, 1993.
    • (1993) Cancer Res , vol.53 , pp. 2140-2146
    • Jin, Y.1    Mertens, F.2    Mandahl, N.3    Heim, S.4    Olegard, C.5    Wennerberg, J.6    Bjorklund, A.7    Mitelman, F.8
  • 40
    • 0026751965 scopus 로고
    • Multiple cytogenetic aberrations in squamous cell carcinomas of the head and neck
    • Owens W, Field JK, Howard PJ and Stell PM: Multiple cytogenetic aberrations in squamous cell carcinomas of the head and neck. Oral Oncol Eur J Cancer 28B: 17-21, 1992.
    • (1992) Oral Oncol Eur J Cancer , vol.28 B , pp. 17-21
    • Owens, W.1    Field, J.K.2    Howard, P.J.3    Stell, P.M.4
  • 41
    • 0029919607 scopus 로고    scopus 로고
    • Frequent gene deletions in potentialy malignant oral lesions
    • Emilion G, Langdon JD, Speight P and Partridge M: Frequent gene deletions in potentialy malignant oral lesions. Br J Cancer 73: 809-813, 1996.
    • (1996) Br J Cancer , vol.73 , pp. 809-813
    • Emilion, G.1    Langdon, J.D.2    Speight, P.3    Partridge, M.4
  • 42
    • 13344262679 scopus 로고    scopus 로고
    • Allelic imbalance on chromosome 3p in oral dysplastic lesions: An early event in oral Carcinogenesis
    • Roz L, Wu CL, Porter SR, Scully C, et al: Allelic imbalance on chromosome 3p in oral dysplastic lesions: an early event in oral Carcinogenesis. Cancer Res 56: 1228-1231, 1996.
    • (1996) Cancer Res , vol.56 , pp. 1228-1231
    • Roz, L.1    Wu, C.L.2    Porter, S.R.3    Scully, C.4
  • 43
    • 0029934699 scopus 로고    scopus 로고
    • Loss of heterozygosity of the short arm of chromosomes 3 and 9 in oral cancer
    • Ishwad CS, Ferrell RE, Rossie KM, et al: Loss of heterozygosity of the short arm of chromosomes 3 and 9 in oral cancer. Int J Cancer 69: 1-4, 1996.
    • (1996) Int J Cancer , vol.69 , pp. 1-4
    • Ishwad, C.S.1    Ferrell, R.E.2    Rossie, K.M.3
  • 44
    • 0030044276 scopus 로고    scopus 로고
    • Chromosome 13q deletion mapping in head and neck squamous cell carcinomas: Identification of two distinct regions of preferential loss
    • Maestro R, Piccinin S, Doglioni C, et al: Chromosome 13q deletion mapping in head and neck squamous cell carcinomas: identification of two distinct regions of preferential loss. Cancer Res 56: 1146-1150, 1996.
    • (1996) Cancer Res , vol.56 , pp. 1146-1150
    • Maestro, R.1    Piccinin, S.2    Doglioni, C.3
  • 45
    • 0030070862 scopus 로고    scopus 로고
    • LOH at 3p correlates with a poor survival in oral squamous cell carcinoma
    • Partridge M, Emilion G and Langdon JD: LOH at 3p correlates with a poor survival in oral squamous cell carcinoma. Br J Cancer 73: 366-371, 1996.
    • (1996) Br J Cancer , vol.73 , pp. 366-371
    • Partridge, M.1    Emilion, G.2    Langdon, J.D.3
  • 46
    • 0029975154 scopus 로고    scopus 로고
    • Definition of a tumor suppressor gene locus on the short arm of chromosome 3 in squamous cell carcinoma of the head and neck by means of microsatellite markers
    • Rowley H, Jones A, Spandidos D and Field J: Definition of a tumor suppressor gene locus on the short arm of chromosome 3 in squamous cell carcinoma of the head and neck by means of microsatellite markers. Arch Otolaryngol Head Neck Surg 122: 497-501, 1996.
    • (1996) Arch Otolaryngol Head Neck Surg , vol.122 , pp. 497-501
    • Rowley, H.1    Jones, A.2    Spandidos, D.3    Field, J.4
  • 47
    • 0030071144 scopus 로고    scopus 로고
    • Frequent allelic loss at chromosome arm 3p is distinct from genetic alterations of the Von-Hippel Lindau tumor suppressor gene in head and neck cancer
    • Waber PG, Lee NK and Nisen PD: Frequent allelic loss at chromosome arm 3p is distinct from genetic alterations of the Von-Hippel Lindau tumor suppressor gene in head and neck cancer. Oncogene 12: 365-369, 1996.
    • (1996) Oncogene , vol.12 , pp. 365-369
    • Waber, P.G.1    Lee, N.K.2    Nisen, P.D.3
  • 49
    • 0028793638 scopus 로고
    • Microsatellite instability in oral cancer
    • Ishwad CS, Ferrell RE, Rossie KM, et al: Microsatellite instability in oral cancer. Int J Cancer 64: 332-335, 1995.
    • (1995) Int J Cancer , vol.64 , pp. 332-335
    • Ishwad, C.S.1    Ferrell, R.E.2    Rossie, K.M.3
  • 50
    • 0025173179 scopus 로고
    • Sequential loss of suppressor genes for three specific functions during in vivo carcinogenesis
    • Moroco JR, Solt DB and Polverini PJ: Sequential loss of suppressor genes for three specific functions during in vivo carcinogenesis. Lab Invest 63: 298-306, 1990.
    • (1990) Lab Invest , vol.63 , pp. 298-306
    • Moroco, J.R.1    Solt, D.B.2    Polverini, P.J.3
  • 51
    • 0029549836 scopus 로고
    • Infrequent Ha-ras mutations and absence of Ki-ras, N-ras and p53 mutations in 4-nitroquinoline 1-oxide-induced rat oral lesions
    • Suzui M, Yoshimi N, Tanaka T and Mori H: Infrequent Ha-ras mutations and absence of Ki-ras, N-ras and p53 mutations in 4-nitroquinoline 1-oxide-induced rat oral lesions. Mol Carcinogen 14:294-298, 1995.
    • (1995) Mol Carcinogen , vol.14 , pp. 294-298
    • Suzui, M.1    Yoshimi, N.2    Tanaka, T.3    Mori, H.4
  • 52
    • 0029925134 scopus 로고    scopus 로고
    • Sequential expression of myc-, ras-, oncogene products and EGF receptor during DMBA-induced tongue carcinogenesis
    • Shintani S, Matsumura T, Alcalde RE and Yoshihama Y: Sequential expression of myc-, ras-, oncogene products and EGF receptor during DMBA-induced tongue carcinogenesis. Int J Oncol 8: 821-826, 1996.
    • (1996) Int J Oncol , vol.8 , pp. 821-826
    • Shintani, S.1    Matsumura, T.2    Alcalde, R.E.3    Yoshihama, Y.4
  • 53
    • 0029919546 scopus 로고    scopus 로고
    • P53 and Ha-ras mutations in chemically induced hamster buccal pouch carcinomas
    • Chang K-W, Lin S-C, Koos S, Pather K and Solt D: P53 and Ha-ras mutations in chemically induced hamster buccal pouch carcinomas. Carcinogenesis 17: 595-600, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 595-600
    • Chang, K.-W.1    Lin, S.-C.2    Koos, S.3    Pather, K.4    Solt, D.5
  • 54
    • 0022415193 scopus 로고
    • Comparative chromosome analysis of nine squamous cell carcinoma cell lines from tumors of the head and neck
    • Hauser-Urfer IF and Stauffer J: Comparative chromosome analysis of nine squamous cell carcinoma cell lines from tumors of the head and neck. Cytogenet Cell Genet 39: 35-39, 1985.
    • (1985) Cytogenet Cell Genet , vol.39 , pp. 35-39
    • Hauser-Urfer, I.F.1    Stauffer, J.2
  • 55
    • 0022458675 scopus 로고
    • Biological studies on ten human squamous cell lines: An overview
    • Easty DM, Easty GC, Bacici A, et al: Biological studies on ten human squamous cell lines: an overview. Eur J Cancer Clin Oncol 22: 617-634, 1986.
    • (1986) Eur J Cancer Clin Oncol , vol.22 , pp. 617-634
    • Easty, D.M.1    Easty, G.C.2    Bacici, A.3
  • 56
    • 12644282831 scopus 로고
    • Non random abnormalities of chromosomes 1 and 11 in squamous cell carcinoma of the head and neck region
    • abs. 34
    • Tharapel SA, Norwood M and Lester EP: Non random abnormalities of chromosomes 1 and 11 in squamous cell carcinoma of the head and neck region. Am Soc Hum Genet 43 (Suppl): abs. 34, 1988.
    • (1988) Am Soc Hum Genet , vol.43 , Issue.SUPPL.
    • Tharapel, S.A.1    Norwood, M.2    Lester, E.P.3
  • 59
    • 0026323511 scopus 로고
    • Serum-free growth and karyotype analyses of cultured normal and tumorous (Sq CC/Y1) human buccal epithelial cells
    • Sundqvist K, Kulkarni P, Hybbinette SS, Bertolero F, Liu Y and Grafstrom RC: Serum-free growth and karyotype analyses of cultured normal and tumorous (Sq CC/Y1) human buccal epithelial cells. Cancer Commun 3: 331-340, 1991.
    • (1991) Cancer Commun , vol.3 , pp. 331-340
    • Sundqvist, K.1    Kulkarni, P.2    Hybbinette, S.S.3    Bertolero, F.4    Liu, Y.5    Grafstrom, R.C.6
  • 60
    • 0028051642 scopus 로고
    • Loss of heterozygosity of chromosome 9p21 is associated with the immortal phenotype of neoplastic human head and neck keratinocytes
    • Loughran O, Edington KG, Berry IJ, Clark LJ and Parkinson EK: Loss of heterozygosity of chromosome 9p21 is associated with the immortal phenotype of neoplastic human head and neck keratinocytes. Cancer Res 54: 5045-5049, 1994.
    • (1994) Cancer Res , vol.54 , pp. 5045-5049
    • Loughran, O.1    Edington, K.G.2    Berry, I.J.3    Clark, L.J.4    Parkinson, E.K.5
  • 61
    • 0028111467 scopus 로고
    • Frequent deletion of chromosome 3p in oral squamous cell carcinoma
    • Partridge M, Kiguwa S and Langdon JD: Frequent deletion of chromosome 3p in oral squamous cell carcinoma. Oral Oncol Eur J Cancer 30B: 248-251, 1994.
    • (1994) Oral Oncol Eur J Cancer , vol.30 B , pp. 248-251
    • Partridge, M.1    Kiguwa, S.2    Langdon, J.D.3
  • 62
    • 0029929885 scopus 로고    scopus 로고
    • Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment
    • Mao L, Lee JS, Fan YH, Ro JY, Batsakis JG, Lippman S, Hittleman W and Hong WK: Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment. Nature Med 2: 682-685, 1996.
    • (1996) Nature Med , vol.2 , pp. 682-685
    • Mao, L.1    Lee, J.S.2    Fan, Y.H.3    Ro, J.Y.4    Batsakis, J.G.5    Lippman, S.6    Hittleman, W.7    Hong, W.K.8
  • 65
    • 0027177767 scopus 로고
    • Polymerase chain reactionbased restriction fragment length polymorphism analysis of the short arm of chromosome 3 in primary head and neck squamous carcinoma
    • El-Naggar AK, Lee M, Wang G, et al: Polymerase chain reactionbased restriction fragment length polymorphism analysis of the short arm of chromosome 3 in primary head and neck squamous carcinoma. Cancer 72: 881-886, 1993.
    • (1993) Cancer , vol.72 , pp. 881-886
    • El-Naggar, A.K.1    Lee, M.2    Wang, G.3
  • 66
    • 0028062854 scopus 로고
    • The relationship of loss of heterozygosity to tobacco exposure and early recurrence in head and neck squamous-cell carcinoma
    • Lydiatt WM, Davidson BJ, Shah J, Schantz SP and Chaganti RSK: The relationship of loss of heterozygosity to tobacco exposure and early recurrence in head and neck squamous-cell carcinoma. Am J Surg 168: 437-440, 1994.
    • (1994) Am J Surg , vol.168 , pp. 437-440
    • Lydiatt, W.M.1    Davidson, B.J.2    Shah, J.3    Schantz, S.P.4    Chaganti, R.S.K.5
  • 67
    • 0026708253 scopus 로고
    • Cytogenetic evidence of the multistep origin of head and neck squamous cell carcinomas
    • Cowan JM, Beckett MA, Ahmed-Swan S and Weichselbaum RR: Cytogenetic evidence of the multistep origin of head and neck squamous cell carcinomas. J Natl Cancer Inst 84: 793-797, 1992.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 793-797
    • Cowan, J.M.1    Beckett, M.A.2    Ahmed-Swan, S.3    Weichselbaum, R.R.4
  • 71
    • 0028343792 scopus 로고
    • Allele loss on chromosome 3 in squamous cell carcinoma of the head and neck correlates with poor clinical prognostic indicators
    • Field JK, Tsiriyotis C, Zoumpourlis V, Howard P, Spandidos DA and Jones AS: Allele loss on chromosome 3 in squamous cell carcinoma of the head and neck correlates with poor clinical prognostic indicators. Int J Oncol 4: 543-549, 1994.
    • (1994) Int J Oncol , vol.4 , pp. 543-549
    • Field, J.K.1    Tsiriyotis, C.2    Zoumpourlis, V.3    Howard, P.4    Spandidos, D.A.5    Jones, A.S.6
  • 73
    • 0028659790 scopus 로고
    • Deletion mapping on the short arm chromosome 3 in squamous cell carcinoma of the oral cavity
    • Wu C-L, Sloan P, Read AP, Harris R and Thakker N: Deletion mapping on the short arm chromosome 3 in squamous cell carcinoma of the oral cavity. Cancer Res 54: 6484-6488, 1994.
    • (1994) Cancer Res , vol.54 , pp. 6484-6488
    • Wu, C.-L.1    Sloan, P.2    Read, A.P.3    Harris, R.4    Thakker, N.5
  • 74
    • 0028828791 scopus 로고
    • Suppression of tumorigenicity in three different cell lines of human oral squamous cell carcinoma by introduction of chromosome 3p via microcell-mediated chromosome transfer
    • Uzawa N, Yoshida MA, Oshimura M and Ikeuchi T: Suppression of tumorigenicity in three different cell lines of human oral squamous cell carcinoma by introduction of chromosome 3p via microcell-mediated chromosome transfer. Oncogene 11: 1997-2004, 1995.
    • (1995) Oncogene , vol.11 , pp. 1997-2004
    • Uzawa, N.1    Yoshida, M.A.2    Oshimura, M.3    Ikeuchi, T.4
  • 76
    • 0028024941 scopus 로고
    • Abnormalities in the adenomatous polyposis coli gene in human oral squamous cell carcinoma
    • Uzawa K, Yoshida H, Susuki H, Tanzawa H, Shimazaki J, Senio S and Sato K: Abnormalities in the adenomatous polyposis coli gene in human oral squamous cell carcinoma. Int J Cancer 58: 814-817, 1994.
    • (1994) Int J Cancer , vol.58 , pp. 814-817
    • Uzawa, K.1    Yoshida, H.2    Susuki, H.3    Tanzawa, H.4    Shimazaki, J.5    Senio, S.6    Sato, K.7
  • 77
    • 0027162572 scopus 로고
    • Increased polysomies of chromosomes 7 and 17 during head and neck multistage tumorigenesis
    • Voravud N, Shin DM, Ro JY, Lee JS, Hong WK and Hittelman WN: Increased polysomies of chromosomes 7 and 17 during head and neck multistage tumorigenesis. Cancer Res 53: 2874-2883, 1993.
    • (1993) Cancer Res , vol.53 , pp. 2874-2883
    • Voravud, N.1    Shin, D.M.2    Ro, J.Y.3    Lee, J.S.4    Hong, W.K.5    Hittelman, W.N.6
  • 78
    • 0024405695 scopus 로고
    • TGF-α and EGF receptor mRNAs in human oral cancers
    • Todd R, Donoff BR, Gertz R, et al: TGF-α and EGF receptor mRNAs in human oral cancers. Carcinogenesis 10: 1553-1556, 1989.
    • (1989) Carcinogenesis , vol.10 , pp. 1553-1556
    • Todd, R.1    Donoff, B.R.2    Gertz, R.3
  • 79
    • 0025774584 scopus 로고
    • Immunohistochemical localization of epidermal growth fact (EGF) and EGF receptor in human oral mucosa and its malignancy
    • Shirasuna K, Hayashido Y, Sugiyama M, Yoshioka H and Matsuya T: Immunohistochemical localization of epidermal growth fact (EGF) and EGF receptor in human oral mucosa and its malignancy. Virchows Arch (A) 418: 349-353, 1991.
    • (1991) Virchows Arch (A) , vol.418 , pp. 349-353
    • Shirasuna, K.1    Hayashido, Y.2    Sugiyama, M.3    Yoshioka, H.4    Matsuya, T.5
  • 80
    • 85007744231 scopus 로고
    • Epidermal growth factor receptor in squamous cell carcinoma and other epidermal lesions of squamous origin: An immunohistochemical study
    • Kunikata M, Yamada K, Yamada T, Mori M, Tatemoto Y and Osaki T: Epidermal growth factor receptor in squamous cell carcinoma and other epidermal lesions of squamous origin: an immunohistochemical study. Acta Histochem Cytochem 25: 387-394, 1992.
    • (1992) Acta Histochem Cytochem , vol.25 , pp. 387-394
    • Kunikata, M.1    Yamada, K.2    Yamada, T.3    Mori, M.4    Tatemoto, Y.5    Osaki, T.6
  • 81
    • 0028021655 scopus 로고
    • The value of epidermal growth factor receptor (EGFR) as a tumor marker for human oral premalignant and malignant lesions
    • Kuttan NAA, Zhang L, Rosin MP, Bhakthan NMG and Priddy RW: The value of epidermal growth factor receptor (EGFR) as a tumor marker for human oral premalignant and malignant lesions. Int J Oncol 5: 955-960, 1994.
    • (1994) Int J Oncol , vol.5 , pp. 955-960
    • Kuttan, N.A.A.1    Zhang, L.2    Rosin, M.P.3    Bhakthan, N.M.G.4    Priddy, R.W.5
  • 82
    • 0027183870 scopus 로고
    • Elevated levels of transforming growth factor áand epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer
    • Grandis JR and Tweardy DJ: Elevated levels of transforming growth factor áand epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer. Cancer Res 53: 3579-3584, 1993.
    • (1993) Cancer Res , vol.53 , pp. 3579-3584
    • Grandis, J.R.1    Tweardy, D.J.2
  • 83
    • 0022624502 scopus 로고
    • Increased EGF receptors on human squamous carcinoma cell lines
    • Cowley GP, Smith JA and Gusterson BA: Increased EGF receptors on human squamous carcinoma cell lines. Br J Cancer 53: 223-239, 1986.
    • (1986) Br J Cancer , vol.53 , pp. 223-239
    • Cowley, G.P.1    Smith, J.A.2    Gusterson, B.A.3
  • 84
    • 0022653770 scopus 로고
    • High incidence of amplification of the epidermal growth factor receptor genes in human squamous carcinoma cell lines
    • Yamamoto T and Kamata N: High incidence of amplification of the epidermal growth factor receptor genes in human squamous carcinoma cell lines. Cancer Res 46: 414-416, 1986.
    • (1986) Cancer Res , vol.46 , pp. 414-416
    • Yamamoto, T.1    Kamata, N.2
  • 85
    • 0022542478 scopus 로고
    • Overexpression of the EGF receptor is a hallmark of squamous cell carcinomas
    • Ozanne B, Richards CS, Hendler F, Bums D and Gusterson B: Overexpression of the EGF receptor is a hallmark of squamous cell carcinomas. J Pathol 149:9-14, 1986.
    • (1986) J Pathol , vol.149 , pp. 9-14
    • Ozanne, B.1    Richards, C.S.2    Hendler, F.3    Bums, D.4    Gusterson, B.5
  • 87
    • 0023220294 scopus 로고
    • Analysis of the epidermal growth factor receptor gene in fresh human head and neck tumours
    • Eisbruch A, Blick M, Lee JS, Sacks PG and Gutterman J: Analysis of the epidermal growth factor receptor gene in fresh human head and neck tumours. Cancer Res 47: 3603-3605, 1987.
    • (1987) Cancer Res , vol.47 , pp. 3603-3605
    • Eisbruch, A.1    Blick, M.2    Lee, J.S.3    Sacks, P.G.4    Gutterman, J.5
  • 89
    • 0024429751 scopus 로고
    • Production of TGF-α and TGF-β by cultured keratinocytes skin and oral squamous cell carcinomas - Potential autocrine regulation of normal and malignant epithelial cell proliferation
    • Partridge M, Green MR, Langdon JD and Feldman M: Production of TGF-α and TGF-β by cultured keratinocytes skin and oral squamous cell carcinomas - potential autocrine regulation of normal and malignant epithelial cell proliferation. Br J Cancer 60: 542-548, 1989.
    • (1989) Br J Cancer , vol.60 , pp. 542-548
    • Partridge, M.1    Green, M.R.2    Langdon, J.D.3    Feldman, M.4
  • 90
    • 0024363095 scopus 로고
    • The expression of epidermal growth factor receptors in the patients with oral cancer
    • Bergler W, Bier H and Ganzer U: The expression of epidermal growth factor receptors in the patients with oral cancer. Arch Otorhinolaryngol 246: 121-125, 1989.
    • (1989) Arch Otorhinolaryngol , vol.246 , pp. 121-125
    • Bergler, W.1    Bier, H.2    Ganzer, U.3
  • 91
    • 0024604427 scopus 로고
    • Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck
    • Ishitoya J, Toriyama M, Oguchi N, Kitamura K, Ohshima M, Asano K and Yamamoto T: Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck. Br J Cancer 59: 559-562, 1989.
    • (1989) Br J Cancer , vol.59 , pp. 559-562
    • Ishitoya, J.1    Toriyama, M.2    Oguchi, N.3    Kitamura, K.4    Ohshima, M.5    Asano, K.6    Yamamoto, T.7
  • 92
    • 0024535206 scopus 로고
    • Epidermal growth factor receptor protein tyrosine kinase activity in human cell lines established from squamous cell carcinomas of the head and neck
    • Maxwell SA, Sacks PG, Gutterman JU and Gallick GE: Epidermal growth factor receptor protein tyrosine kinase activity in human cell lines established from squamous cell carcinomas of the head and neck. Cancer Res 49: 1130-1137, 1989.
    • (1989) Cancer Res , vol.49 , pp. 1130-1137
    • Maxwell, S.A.1    Sacks, P.G.2    Gutterman, J.U.3    Gallick, G.E.4
  • 93
    • 0002956137 scopus 로고
    • Increased EGF-R1 binding predicts a poor survival in squamous tumours
    • Hendler FJ, Shum-Siu A, Oeschsli M, et al: Increased EGF-R1 binding predicts a poor survival in squamous tumours. Cancer Cells 7: 347-351, 1989.
    • (1989) Cancer Cells , vol.7 , pp. 347-351
    • Hendler, F.J.1    Shum-Siu, A.2    Oeschsli, M.3
  • 94
    • 0024513581 scopus 로고
    • Activation of oncogenes in human oral cancer cells: A novel codon 13 mutation of c-Ha-ras-1 and concurrent amplifications of c-erbB-1 and c-myc
    • Tadokoro K, Ueda M, Ohshima T, Fujita K, Rikimaru K, Takashashi N, Enomoto S and Tschuchida N: Activation of oncogenes in human oral cancer cells: a novel codon 13 mutation of c-Ha-ras-1 and concurrent amplifications of c-erbB-1 and c-myc. Oncogene 4: 499-505, 1989.
    • (1989) Oncogene , vol.4 , pp. 499-505
    • Tadokoro, K.1    Ueda, M.2    Ohshima, T.3    Fujita, K.4    Rikimaru, K.5    Takashashi, N.6    Enomoto, S.7    Tschuchida, N.8
  • 96
    • 0025304583 scopus 로고
    • Immunohistochemical localization of c-myc and EGF receptor gene products in oral squamous cell carcinoma
    • Sakai H, Kawano K, Okamura K and Hashimoto N: Immunohistochemical localization of c-myc and EGF receptor gene products in oral squamous cell carcinoma. J Oral Pathol Med 19: 1-4, 1990.
    • (1990) J Oral Pathol Med , vol.19 , pp. 1-4
    • Sakai, H.1    Kawano, K.2    Okamura, K.3    Hashimoto, N.4
  • 97
    • 0025333824 scopus 로고
    • Amplification of the Int-2 gene in human head and neck squamous cell carcinomas
    • Somers KD, Cartwright SL and Schechter GL: Amplification of the Int-2 gene in human head and neck squamous cell carcinomas. Oncogene 5: 915-920, 1990.
    • (1990) Oncogene , vol.5 , pp. 915-920
    • Somers, K.D.1    Cartwright, S.L.2    Schechter, G.L.3
  • 98
    • 0026343328 scopus 로고
    • Epidermal growth factor receptor amplification in head and neck cancer
    • El-Zayat EAA, Pingree TG, Mock PM, et al: Epidermal growth factor receptor amplification in head and neck cancer. Cancer J 4: 375-379, 1991.
    • (1991) Cancer J , vol.4 , pp. 375-379
    • El-Zayat, E.A.A.1    Pingree, T.G.2    Mock, P.M.3
  • 99
    • 0026344914 scopus 로고
    • Gene amplification and gene dosage in cell lines derived from squamous cell carcinoma of the head and neck
    • Yin XY, Donovanpeluso M, Whiteside TL, et al: Gene amplification and gene dosage in cell lines derived from squamous cell carcinoma of the head and neck. Genes Chromosom Cancer 3: 443-454, 1991.
    • (1991) Genes Chromosom Cancer , vol.3 , pp. 443-454
    • Yin, X.Y.1    Donovanpeluso, M.2    Whiteside, T.L.3
  • 100
    • 0010233988 scopus 로고
    • Growth stimulation of A431 cells by epidermal growth factor: Identification of high affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody
    • Kawamoto T, Sato JD, Polikoff ALJ, Sato GH and Mendelsohn J: Growth stimulation of A431 cells by epidermal growth factor: identification of high affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody. Proc Natl Acad Sci USA 80: 1337, 1983.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 1337
    • Kawamoto, T.1    Sato, J.D.2    Polikoff, A.L.J.3    Sato, G.H.4    Mendelsohn, J.5
  • 101
    • 0025753351 scopus 로고
    • Quantitative assay of epidermal growth factor receptor in human squamous cell carcinomas of the oral region by an avidin-biotin method
    • Kawamoto T, Takahashi K, Nishi M, Kimura T, Matsumura T and Taniguchi S: Quantitative assay of epidermal growth factor receptor in human squamous cell carcinomas of the oral region by an avidin-biotin method. Jpn J Cancer Res 82: 403-410, 1991.
    • (1991) Jpn J Cancer Res , vol.82 , pp. 403-410
    • Kawamoto, T.1    Takahashi, K.2    Nishi, M.3    Kimura, T.4    Matsumura, T.5    Taniguchi, S.6
  • 102
    • 0025362139 scopus 로고
    • Tumour progression in experimental oral carcinogenesis is associated with changes in EGF and TGF-β receptor expression and altered responses to these growth factors
    • Game SM, Stone A, Scully C and Prime SS: Tumour progression in experimental oral carcinogenesis is associated with changes in EGF and TGF-β receptor expression and altered responses to these growth factors. Carcinogenesis 11: 965-973, 1990.
    • (1990) Carcinogenesis , vol.11 , pp. 965-973
    • Game, S.M.1    Stone, A.2    Scully, C.3    Prime, S.S.4
  • 103
    • 0025013088 scopus 로고
    • Expression of c-erbB-2 and c-myc in squamous epithelia and squamous cell carcinomas of the head and neck and the lower female genital tract
    • Riviere A, Wilckens C and Loning T: Expression of c-erbB-2 and c-myc in squamous epithelia and squamous cell carcinomas of the head and neck and the lower female genital tract. J Oral Pathol Med 19: 408-413, 1990.
    • (1990) J Oral Pathol Med , vol.19 , pp. 408-413
    • Riviere, A.1    Wilckens, C.2    Loning, T.3
  • 104
    • 0025905507 scopus 로고
    • Comparative investigation of c-erbB-2/neu expression in head and neck tumors and mammary cancer
    • Riviere A, Becker J and Loning T: Comparative investigation of c-erbB-2/neu expression in head and neck tumors and mammary cancer. Cancer 67: 2142-2149, 1991.
    • (1991) Cancer , vol.67 , pp. 2142-2149
    • Riviere, A.1    Becker, J.2    Loning, T.3
  • 105
    • 0026324504 scopus 로고
    • A comparison of epidermal growth factor receptor (EGFR) and c-erbB-2 oncogene expression in head and neck squamous cell carcinomas
    • Kearsley JH, Leonard JH, Walsh M and Wright GR: A comparison of epidermal growth factor receptor (EGFR) and c-erbB-2 oncogene expression in head and neck squamous cell carcinomas. Pathology 23: 189-194, 1991.
    • (1991) Pathology , vol.23 , pp. 189-194
    • Kearsley, J.H.1    Leonard, J.H.2    Walsh, M.3    Wright, G.R.4
  • 107
    • 0026061104 scopus 로고
    • Characterization, quantification and potential clinical value of epidermal growth factor receptor in head and neck squamous cell carcinomas
    • Santini J, Formento JL, Frauncoual M, Milano G, Schneider M, Dassonville O and Demard E: Characterization, quantification and potential clinical value of epidermal growth factor receptor in head and neck squamous cell carcinomas. Head Neck 13: 132-139, 1991.
    • (1991) Head Neck , vol.13 , pp. 132-139
    • Santini, J.1    Formento, J.L.2    Frauncoual, M.3    Milano, G.4    Schneider, M.5    Dassonville, O.6    Demard, E.7
  • 108
    • 9044221839 scopus 로고
    • Growth factors and their receptors as markers of the high risk lesion, with special reference to epidermal growth factors
    • Johnson NW (ed). Cambridge University Press, Cambridge
    • Talacko AA, Shirlaw PJ and Johnson NW: Growth factors and their receptors as markers of the high risk lesion, with special reference to epidermal growth factors. In: Risk Markers for Oral Diseases. Oral Cancer. Detection of patients and lesions at risk. Johnson NW (ed). Vol. 2. Cambridge University Press, Cambridge, pp29-316, 1991.
    • (1991) Risk Markers for Oral Diseases. Oral Cancer. Detection of Patients and Lesions at Risk , vol.2 , pp. 29-316
    • Talacko, A.A.1    Shirlaw, P.J.2    Johnson, N.W.3
  • 111
    • 0026584304 scopus 로고
    • Gene amplification and overexpression of epidermal growth factor receptor in squamous cell carcinoma of the head and neck
    • Rikimaru K, Tadokoro K, Yamamoto T, Enomoto S and Tsuchida N: Gene amplification and overexpression of epidermal growth factor receptor in squamous cell carcinoma of the head and neck. Head Neck 14: 8-13, 1992.
    • (1992) Head Neck , vol.14 , pp. 8-13
    • Rikimaru, K.1    Tadokoro, K.2    Yamamoto, T.3    Enomoto, S.4    Tsuchida, N.5
  • 112
    • 0026448253 scopus 로고
    • Amplification and overexpression of epidermal growth factor receptor gene in human oropharyngeal cancer
    • Saranath D, Panchal RG, Nair R, Mehta AR, Sanghavi VD and Deo MG: Amplification and overexpression of epidermal growth factor receptor gene in human oropharyngeal cancer. Oral Oncol Eur J Cancer 28B: 139-143, 1992.
    • (1992) Oral Oncol Eur J Cancer , vol.28 B , pp. 139-143
    • Saranath, D.1    Panchal, R.G.2    Nair, R.3    Mehta, A.R.4    Sanghavi, V.D.5    Deo, M.G.6
  • 113
    • 0026582296 scopus 로고
    • Evaluation of epidermal growth factor receptor in squamous cell carcinoma of the oral cavity
    • Yamada T, Takagi M and Shioda S: Evaluation of epidermal growth factor receptor in squamous cell carcinoma of the oral cavity. Oral Surg Oral Med Oral Pathol 73: 67-70, 1992.
    • (1992) Oral Surg Oral Med Oral Pathol , vol.73 , pp. 67-70
    • Yamada, T.1    Takagi, M.2    Shioda, S.3
  • 115
    • 0027524082 scopus 로고
    • Oncogenes in head and neck cancer
    • Irish JC and Bernstein A: Oncogenes in head and neck cancer. Laryngoscope 103:42-52, 1993.
    • (1993) Laryngoscope , vol.103 , pp. 42-52
    • Irish, J.C.1    Bernstein, A.2
  • 119
    • 0028317004 scopus 로고
    • Co-expression of ras p21 and epidermal growth factor receptor during various stages of tumour progression in oral mucosa
    • Kannan S, Balaram P, Chandran BJ, Pillai MR, Mathew B and Nair MK: Co-expression of ras p21 and epidermal growth factor receptor during various stages of tumour progression in oral mucosa. Tumor Biol 15: 73-81, 1994.
    • (1994) Tumor Biol , vol.15 , pp. 73-81
    • Kannan, S.1    Balaram, P.2    Chandran, B.J.3    Pillai, M.R.4    Mathew, B.5    Nair, M.K.6
  • 120
    • 0027432231 scopus 로고
    • EGFR and PCNA expression in oral squamous cell carcinomas - A valuable tool in estimating the patient's prognosis
    • Storkel S, Reichart T, Reiffen KA and Wagner W: EGFR and PCNA expression in oral squamous cell carcinomas - a valuable tool in estimating the patient's prognosis. Oral Oncol Eur J Cancer 29B: 273-277, 1993.
    • (1993) Oral Oncol Eur J Cancer , vol.29 B , pp. 273-277
    • Storkel, S.1    Reichart, T.2    Reiffen, K.A.3    Wagner, W.4
  • 121
    • 0029943264 scopus 로고    scopus 로고
    • Correlation of transforming growth factor áand epidermal growth factor receptor in oropharyngeal carcinomas
    • Bergler W, Petroianu G, Juncker C and Hormann K: Correlation of transforming growth factor áand epidermal growth factor receptor in oropharyngeal carcinomas. Acta Oto-laryngol 116: 486-489, 1996.
    • (1996) Acta Oto-laryngol , vol.116 , pp. 486-489
    • Bergler, W.1    Petroianu, G.2    Juncker, C.3    Hormann, K.4
  • 122
    • 0028292482 scopus 로고
    • Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis
    • Shin DM, Ro JY, Hong WK and Hittelman WN: Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis. Cancer Res 54: 3153-3159, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3153-3159
    • Shin, D.M.1    Ro, J.Y.2    Hong, W.K.3    Hittelman, W.N.4
  • 123
    • 0026518226 scopus 로고
    • Cytogenetic studies of eight squamous cell carcinomas of the head and neck. Deletion of 7q, a possible primary chromosomal event
    • Osella P, Carlson A, Wyandt H and Milungky A: Cytogenetic studies of eight squamous cell carcinomas of the head and neck. Deletion of 7q, a possible primary chromosomal event. Cancer Genet Cytogenet 59: 73-78, 1992.
    • (1992) Cancer Genet Cytogenet , vol.59 , pp. 73-78
    • Osella, P.1    Carlson, A.2    Wyandt, H.3    Milungky, A.4
  • 124
    • 0028170396 scopus 로고
    • Loss of heterozygosity and microsatellite instability of the H-ras gene in cancer of the head and neck
    • Kiaris H, Spandidos DA, Jones AS and Field JK: Loss of heterozygosity and microsatellite instability of the H-ras gene in cancer of the head and neck. Int J Oncol 5: 579-582, 1994.
    • (1994) Int J Oncol , vol.5 , pp. 579-582
    • Kiaris, H.1    Spandidos, D.A.2    Jones, A.S.3    Field, J.K.4
  • 126
    • 0027406542 scopus 로고
    • Evidence for the presence of two tumor suppressor genes on chromosome 8p for colorectal carcinoma
    • Fujiwara Y, Emi M, Ohata H, Kato Y, Nakajima T, Mori T and Nakamura Y: Evidence for the presence of two tumor suppressor genes on chromosome 8p for colorectal carcinoma. Cancer Res 53: 1172-1174, 1993.
    • (1993) Cancer Res , vol.53 , pp. 1172-1174
    • Fujiwara, Y.1    Emi, M.2    Ohata, H.3    Kato, Y.4    Nakajima, T.5    Mori, T.6    Nakamura, Y.7
  • 127
    • 0027324631 scopus 로고
    • Deletion mapping of chromosome 8 in cancers of the urinary bladder using restriction fragment length polymorphisms and microsatellite polymorphisms
    • Knowles MA, Shaw ME and Proctor AJ: Deletion mapping of chromosome 8 in cancers of the urinary bladder using restriction fragment length polymorphisms and microsatellite polymorphisms. Oncogene 8: 1357-1364, 1993.
    • (1993) Oncogene , vol.8 , pp. 1357-1364
    • Knowles, M.A.1    Shaw, M.E.2    Proctor, A.J.3
  • 128
    • 0028113758 scopus 로고
    • Loss of heterozygosity of chromosome 8 microsatellite loci implicates a candidate tumor suppressor gene between the loci D8S87 and D8S133 in human prostate cancer
    • Trapman J, Sleddens HF, van der Weiden MM, Dinjins WN, Konig JJ, Schroder FH, Faber PW and Bosman FT: Loss of heterozygosity of chromosome 8 microsatellite loci implicates a candidate tumor suppressor gene between the loci D8S87 and D8S133 in human prostate cancer. Cancer Res 54: 6061-6064, 1994.
    • (1994) Cancer Res , vol.54 , pp. 6061-6064
    • Trapman, J.1    Sleddens, H.F.2    Van Der Weiden, M.M.3    Dinjins, W.N.4    Konig, J.J.5    Schroder, F.H.6    Faber, P.W.7    Bosman, F.T.8
  • 129
    • 0027278766 scopus 로고
    • c-myc oncoprotein expression in oral precancerous and early cancerous lesions
    • Eversole LR and Sapp JP: c-myc oncoprotein expression in oral precancerous and early cancerous lesions. Oral Oncol Eur J Cancer 29B: 131-135, 1993.
    • (1993) Oral Oncol Eur J Cancer , vol.29 B , pp. 131-135
    • Eversole, L.R.1    Sapp, J.P.2
  • 130
    • 0022038637 scopus 로고
    • Multiple transcriptional activation of cellular oncogenes in human head and neck solid tumours
    • Spandidos DA, Lamothe A and Field JK: Multiple transcriptional activation of cellular oncogenes in human head and neck solid tumours. Anticancer Res 5: 221-224, 1985.
    • (1985) Anticancer Res , vol.5 , pp. 221-224
    • Spandidos, D.A.1    Lamothe, A.2    Field, J.K.3
  • 131
    • 0022572014 scopus 로고
    • Alterations of myc, myb and Ha-ras proto-oncogene in cancers are frequent and show clinical correlations
    • Yokota J, Tsuwetsugu-Yokota V, Battifora H, Le Febre C and Cline JJ: Alterations of myc, myb and Ha-ras proto-oncogene in cancers are frequent and show clinical correlations. Science 231: 261-267, 1986.
    • (1986) Science , vol.231 , pp. 261-267
    • Yokota, J.1    Tsuwetsugu-Yokota, V.2    Battifora, H.3    Le Febre, C.4    Cline, J.J.5
  • 133
    • 0025304583 scopus 로고
    • Immunohistochemical localization of c-myc oncogene product and EGF receptor in oral squamous cell carcinoma
    • Kawano SH, Okamura K and Hashimoto N: Immunohistochemical localization of c-myc oncogene product and EGF receptor in oral squamous cell carcinoma. J Oral Pathol Med 19: 1-4, 1990.
    • (1990) J Oral Pathol Med , vol.19 , pp. 1-4
    • Kawano, S.H.1    Okamura, K.2    Hashimoto, N.3
  • 135
    • 12644258802 scopus 로고
    • Expression des oncogenes c-erbB-2 et c-myc dans des tumeurs humaines des voies aerodigestives superieures
    • Muller D, Millon R, Eber M, Abecassis J and Methlin G: Expression des oncogenes c-erbB-2 et c-myc dans des tumeurs humaines des voies aerodigestives superieures. Bull Cancer 77: 535, 1990.
    • (1990) Bull Cancer , vol.77 , pp. 535
    • Muller, D.1    Millon, R.2    Eber, M.3    Abecassis, J.4    Methlin, G.5
  • 137
    • 0028947875 scopus 로고
    • The role of oncogenes and tumour-suppressor genes in the aetiology of oral, head and neck squamous cell carcinoma
    • Field JK: The role of oncogenes and tumour-suppressor genes in the aetiology of oral, head and neck squamous cell carcinoma. J R Soc Med 88: 9-35, 1995.
    • (1995) J R Soc Med , vol.88 , pp. 9-35
    • Field, J.K.1
  • 138
    • 0030002466 scopus 로고    scopus 로고
    • MYC amplification in squamous cell carcinomas of the head and neck
    • Rodrigo JP, Lazo PS, Ramos S, et al; MYC amplification in squamous cell carcinomas of the head and neck. Arch Otolaryngol Head Neck Surg 122: 504-507, 1996.
    • (1996) Arch Otolaryngol Head Neck Surg , vol.122 , pp. 504-507
    • Rodrigo, J.P.1    Lazo, P.S.2    Ramos, S.3
  • 142
    • 0029061585 scopus 로고
    • Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma
    • El-Naggar AK, Hurr K, Batsakis JG, Luna MA, Goepfert H and Huff V: Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma. Cancer Res 55: 2656-2659, 1995.
    • (1995) Cancer Res , vol.55 , pp. 2656-2659
    • El-Naggar, A.K.1    Hurr, K.2    Batsakis, J.G.3    Luna, M.A.4    Goepfert, H.5    Huff, V.6
  • 143
    • 0029115890 scopus 로고
    • Chromosome 18: A possible site for a tumour suppressor gene deletion in squamous cell carcinoma of the head and neck
    • Rowley H, Jones AS and Field JK: Chromosome 18: a possible site for a tumour suppressor gene deletion in squamous cell carcinoma of the head and neck. Clin Otolaryngol 20: 266-271, 1995.
    • (1995) Clin Otolaryngol , vol.20 , pp. 266-271
    • Rowley, H.1    Jones, A.S.2    Field, J.K.3
  • 144
    • 0028302819 scopus 로고
    • Homozygous and hemizygous deletions of 9p centromeric to the interferon genes in lung cancer
    • Mead LJ, Gillespie MT, Irving LB and Campbell LJ:-Homozygous and hemizygous deletions of 9p centromeric to the interferon genes in lung cancer. Cancer Res 54: 2307-2309, 1994.
    • (1994) Cancer Res , vol.54 , pp. 2307-2309
    • Mead, L.J.1    Gillespie, M.T.2    Irving, L.B.3    Campbell, L.J.4
  • 145
    • 0028275733 scopus 로고
    • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • Nobori T, Miura K, Wu DJ, Lois A, Takabayaski K and Carson DA: Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 368: 753-755, 1994.
    • (1994) Nature , vol.368 , pp. 753-755
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayaski, K.5    Carson, D.A.6
  • 146
    • 0029088549 scopus 로고
    • Loss of heterozygosity at 9p23 defines a novel locus in nonsmall cell lung cancer
    • Neville EM, Stewart MP, Myskow M, Donnelly RJ and Field JK: Loss of heterozygosity at 9p23 defines a novel locus in nonsmall cell lung cancer. Oncogene 11: 581-585, 1995.
    • (1995) Oncogene , vol.11 , pp. 581-585
    • Neville, E.M.1    Stewart, M.P.2    Myskow, M.3    Donnelly, R.J.4    Field, J.K.5
  • 147
    • 0028270326 scopus 로고
    • Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer
    • Merlo A, Gabrielson E, Mabry M, Vollmer R, Baylin SB and Sidransky D: Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer. Cancer Res 54: 2322-2326, 1994.
    • (1994) Cancer Res , vol.54 , pp. 2322-2326
    • Merlo, A.1    Gabrielson, E.2    Mabry, M.3    Vollmer, R.4    Baylin, S.B.5    Sidransky, D.6
  • 148
  • 149
    • 0030091666 scopus 로고    scopus 로고
    • Cyclin D1-PRAD-1 as a central target in oncogenesis
    • Hosokawa Y and Arnold A: Cyclin D1-PRAD-1 as a central target in oncogenesis. J Lab Clin Med 127: 246-252, 1996.
    • (1996) J Lab Clin Med , vol.127 , pp. 246-252
    • Hosokawa, Y.1    Arnold, A.2
  • 150
    • 0028033422 scopus 로고
    • Rates of p16 (MTS-1) mutations in primary tumours with 9p loss
    • Cairns P: Rates of p16 (MTS-1) mutations in primary tumours with 9p loss. Science 265: 415-416, 1994.
    • (1994) Science , vol.265 , pp. 415-416
    • Cairns, P.1
  • 152
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS-1 in human cancers
    • Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, Baylin SB and Sidransky D: 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS-1 in human cancers. Nature Med 1: 686-692, 1995.
    • (1995) Nature Med , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sidransky, D.8
  • 158
    • 0028566272 scopus 로고
    • MTS-1/CDK41 is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma
    • Yeudall WA, Crawford RY, Ensley JD and Robbins KC: MTS-1/CDK41 is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma. Carcinogenesis 15: 2683-2686, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 2683-2686
    • Yeudall, W.A.1    Crawford, R.Y.2    Ensley, J.D.3    Robbins, K.C.4
  • 159
    • 0028138707 scopus 로고
    • Higher frequency of alterations in p16/CDKN2 gene in squamous cell
    • Ahang S, Klein-Szanto AJP, Sauter ER, et al: Higher frequency of alterations in p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck. Cancer Res 54: 5050-5053, 1994.
    • (1994) Cancer Res , vol.54 , pp. 5050-5053
    • Ahang, S.1    Klein-Szanto, A.J.P.2    Sauter, E.R.3
  • 160
    • 0029963169 scopus 로고    scopus 로고
    • p16 inhibition of transformed and primary squamous epithelial cells
    • Enders GH, Koh J, Missero C, Rustgi AK and Harlow E: p16 inhibition of transformed and primary squamous epithelial cells. Oncogene 12: 1239-1245, 1996.
    • (1996) Oncogene , vol.12 , pp. 1239-1245
    • Enders, G.H.1    Koh, J.2    Missero, C.3    Rustgi, A.K.4    Harlow, E.5
  • 161
    • 0029060026 scopus 로고
    • Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck
    • Kiaris H, Spandidos DA, Jones AS, Vaughan ED and Field JK: Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck. Br J Cancer 72: 123-128, 1995.
    • (1995) Br J Cancer , vol.72 , pp. 123-128
    • Kiaris, H.1    Spandidos, D.A.2    Jones, A.S.3    Vaughan, E.D.4    Field, J.K.5
  • 163
    • 0025063619 scopus 로고
    • Analysis of the c-Ha-ras-1 gene for deletion, mutation, amplification and expression in lymph node metastases of human head and neck carcinomas
    • Sheng ZM, Barrois M, Klijanienko J, Micheau C, Richard JM and Riou G: Analysis of the c-Ha-ras-1 gene for deletion, mutation, amplification and expression in lymph node metastases of human head and neck carcinomas. Br J Cancer 62: 398-404, 1990.
    • (1990) Br J Cancer , vol.62 , pp. 398-404
    • Sheng, Z.M.1    Barrois, M.2    Klijanienko, J.3    Micheau, C.4    Richard, J.M.5    Riou, G.6
  • 166
    • 0024397085 scopus 로고
    • Frequent amplification of the bcl-1 locus in head and neck squamous cell carcinomas
    • Berenson JR, Yang J and Mickel RA: Frequent amplification of the bcl-1 locus in head and neck squamous cell carcinomas. Oncogene4: 111-11116, 1989.
    • (1989) Oncogene , vol.4 , pp. 111-11116
    • Berenson, J.R.1    Yang, J.2    Mickel, R.A.3
  • 167
    • 0026521388 scopus 로고
    • Identification and cloning of 2 overexpressed genes, U21B31/ PRAD-1 and EMS-1, within the amplified chromosome 11q13 region in human carcinomas
    • Schuuring E, Verhoeven E, Mool WJ and Michalides RJAM: Identification and cloning of 2 overexpressed genes, U21B31/ PRAD-1 and EMS-1, within the amplified chromosome 11q13 region in human carcinomas. Oncogene 7: 355-361, 1992.
    • (1992) Oncogene , vol.7 , pp. 355-361
    • Schuuring, E.1    Verhoeven, E.2    Mool, W.J.3    Michalides, R.J.A.M.4
  • 168
    • 0025970229 scopus 로고
    • D11S287, a purative oncogene in chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BDL-I
    • Lammie GA, Fantl V, Smith R, Schuuring ED, Brookes S and Michalides R: D11S287, a purative oncogene in chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BDL-I. Oncogene 6: 439-444, 1991.
    • (1991) Oncogene , vol.6 , pp. 439-444
    • Lammie, G.A.1    Fantl, V.2    Smith, R.3    Schuuring, E.D.4    Brookes, S.5    Michalides, R.6
  • 169
    • 0026075824 scopus 로고
    • Chromosome 11q1S abnormalities in human cancer
    • Lammie GA and Peters G: Chromosome 11q1S abnormalities in human cancer. Cancer Cells 3: 413-420, 1991.
    • (1991) Cancer Cells , vol.3 , pp. 413-420
    • Lammie, G.A.1    Peters, G.2
  • 170
    • 0027464236 scopus 로고
    • Unexpected PRAD-1 amplification in multiple simultaneous localizations of squamous cell carcinoma of the head and neck
    • Klijanienko J, Bianchi AB, Cvitkovic E, Janot F, Luboinski B and Conti CJ: Unexpected PRAD-1 amplification in multiple simultaneous localizations of squamous cell carcinoma of the head and neck. Eur J Cancer 29: 563-564, 1993.
    • (1993) Eur J Cancer , vol.29 , pp. 563-564
    • Klijanienko, J.1    Bianchi, A.B.2    Cvitkovic, E.3    Janot, F.4    Luboinski, B.5    Conti, C.J.6
  • 172
    • 0028200882 scopus 로고
    • PRAD-1 (CCND1)/cyclin D1 oncogene amplification in primary head and neck squamous cell carcinoma
    • Callender T, El-Naggar AK, Lee MS, Frankenthaler R, Luna MA and Batsakis JG: PRAD-1 (CCND1)/cyclin D1 oncogene amplification in primary head and neck squamous cell carcinoma. Cancer 74: 152-158, 1994.
    • (1994) Cancer , vol.74 , pp. 152-158
    • Callender, T.1    El-Naggar, A.K.2    Lee, M.S.3    Frankenthaler, R.4    Luna, M.A.5    Batsakis, J.G.6
  • 174
    • 0028022741 scopus 로고
    • Chromosome 11q13 gene amplifications in head and neck squamous cell carcinomas: Relation with lymph node invasion
    • Parise O, Janot F and Guerry R: Chromosome 11q13 gene amplifications in head and neck squamous cell carcinomas: relation with lymph node invasion. Int J Oncol 5: 309-313, 1994.
    • (1994) Int J Oncol , vol.5 , pp. 309-313
    • Parise, O.1    Janot, F.2    Guerry, R.3
  • 175
    • 0028810532 scopus 로고
    • Cyclin D1 (PRAD-1, CCND1) and glutathione-S-transferase π gene expression in head and neck squamous cell carcinoma
    • Gaffey MJ, lezzoni JC, Meredit SD, et al: Cyclin D1 (PRAD-1, CCND1) and glutathione-S-transferase π gene expression in head and neck squamous cell carcinoma. Hum Pathol 26: 1221-1226, 1995.
    • (1995) Hum Pathol , vol.26 , pp. 1221-1226
    • Gaffey, M.J.1    Lezzoni, J.C.2    Meredit, S.D.3
  • 176
    • 0027469208 scopus 로고
    • Coamplification of the hst and bcl-1 oncogenes in advanced squamous cell carcinomas of the head and neck
    • Volling P, Jungejulsing M, Jucker M, Stutzer H, Diehl V and Tesch H: Coamplification of the hst and bcl-1 oncogenes in advanced squamous cell carcinomas of the head and neck. Eur J Cancer 29A: 383-389, 1993.
    • (1993) Eur J Cancer , vol.29 A , pp. 383-389
    • Volling, P.1    Jungejulsing, M.2    Jucker, M.3    Stutzer, H.4    Diehl, V.5    Tesch, H.6
  • 177
    • 0023841241 scopus 로고
    • Amplification of human Int-2 in breast cancers and squamous carcinomas
    • Zhou DJ, Casey G and Cline MJ: Amplification of human Int-2 in breast cancers and squamous carcinomas. Oncogene 2: 279-282, 1988.
    • (1988) Oncogene , vol.2 , pp. 279-282
    • Zhou, D.J.1    Casey, G.2    Cline, M.J.3
  • 178
    • 0028894280 scopus 로고
    • Abnormal patterns of D-type cyclin expression and G1 regulation in human head and neck cancer
    • Bartkova J, Lukas J, Muller H, et al: Abnormal patterns of D-type cyclin expression and G1 regulation in human head and neck cancer. Cancer Res 55: 949-956, 1995.
    • (1995) Cancer Res , vol.55 , pp. 949-956
    • Bartkova, J.1    Lukas, J.2    Muller, H.3
  • 179
    • 0028953560 scopus 로고
    • Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck
    • Michalides R, van Veelen N, Hart A, Loftus B, Wientjens E and Balm A: Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck. Cancer Res 55: 975-978, 1995.
    • (1995) Cancer Res , vol.55 , pp. 975-978
    • Michalides, R.1    Van Veelen, N.2    Hart, A.3    Loftus, B.4    Wientjens, E.5    Balm, A.6
  • 180
    • 0027976222 scopus 로고
    • Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: Link between cell cycle control and malignant transformation
    • Lovec H, Sewing A, Lucibello FC, Muller R and Moroy T: Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: link between cell cycle control and malignant transformation. Oncogene 9: 323-326, 1994.
    • (1994) Oncogene , vol.9 , pp. 323-326
    • Lovec, H.1    Sewing, A.2    Lucibello, F.C.3    Muller, R.4    Moroy, T.5
  • 181
    • 0023226760 scopus 로고
    • The relation of ras oncogene product p21 expression to clinicopathological status and clinical outcome in squamous cell head and neck cancer
    • Azuma M, Furumoto N, Kawamata H, Yoshide H, Yanagawa T, Yura Y, Takegawa Y and Sato M: The relation of ras oncogene product p21 expression to clinicopathological status and clinical outcome in squamous cell head and neck cancer. Cancer J 1: 375-380, 1987.
    • (1987) Cancer J , vol.1 , pp. 375-380
    • Azuma, M.1    Furumoto, N.2    Kawamata, H.3    Yoshide, H.4    Yanagawa, T.5    Yura, Y.6    Takegawa, Y.7    Sato, M.8
  • 183
    • 0025732716 scopus 로고
    • High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India
    • Saranath D, Chang SE, Bhoite LT, et al:. High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India. Br J Cancer 63: 573-578, 1991.
    • (1991) Br J Cancer , vol.63 , pp. 573-578
    • Saranath, D.1    Chang, S.E.2    Bhoite, L.T.3
  • 184
    • 0028500793 scopus 로고
    • Immunohistochemical detection of the H-ras, K-ras, and N-ras oncogenes in squamous cell carcinoma of the head and neck
    • McDonald JS, Jones H, Pavelic ZP, Pavelic LJ, Stambrook PJ and Gluckmari JL: Immunohistochemical detection of the H-ras, K-ras, and N-ras oncogenes in squamous cell carcinoma of the head and neck. J Oral Pathol Med 23: 342-346, 1994.
    • (1994) J Oral Pathol Med , vol.23 , pp. 342-346
    • McDonald, J.S.1    Jones, H.2    Pavelic, Z.P.3    Pavelic, L.J.4    Stambrook, P.J.5    Gluckmari, J.L.6
  • 186
    • 0025237434 scopus 로고
    • Low incidence of ras oncogene activation in human squamous cell carcinomas
    • Rumsby G, Carter RL and Gusterson BA: Low incidence of ras oncogene activation in human squamous cell carcinomas. Br J Cancer 61: 365-368, 1990.
    • (1990) Br J Cancer , vol.61 , pp. 365-368
    • Rumsby, G.1    Carter, R.L.2    Gusterson, B.A.3
  • 187
    • 0025890028 scopus 로고
    • Ras mutations in United Kingdom examples of oral malignancies are infrequent
    • Chang SE, Bhatia P, Johnson NW, et al: Ras mutations in United Kingdom examples of oral malignancies are infrequent. Int J Cancer 48: 409-412, 1991.
    • (1991) Int J Cancer , vol.48 , pp. 409-412
    • Chang, S.E.1    Bhatia, P.2    Johnson, N.W.3
  • 188
    • 0026719081 scopus 로고
    • Point mutations in Ha-ras oncogene are detectable in formalin-fixed tissues of oral squamous cell carcinomas, but are infrequent in British cases
    • Warnakulasuriya KAAS, Chang SE and Johnson NW: Point mutations in Ha-ras oncogene are detectable in formalin-fixed tissues of oral squamous cell carcinomas, but are infrequent in British cases. J Oral Pathol Med 21: 225-229, 1992.
    • (1992) J Oral Pathol Med , vol.21 , pp. 225-229
    • Warnakulasuriya, K.A.A.S.1    Chang, S.E.2    Johnson, N.W.3
  • 190
    • 0027474504 scopus 로고
    • Ras gene point mutation is a rare event in premalignant tissues and malignant cells and tissues from oral mucosal lesions
    • Yeudall WA, Torrance LK, Elsegood KA, Speight P, Scully C and Prime SS: Ras gene point mutation is a rare event in premalignant tissues and malignant cells and tissues from oral mucosal lesions. Oral Oncol Eur J Cancer: 29B: 63-67, 1993.
    • (1993) Oral Oncol Eur J Cancer , vol.29 B , pp. 63-67
    • Yeudall, W.A.1    Torrance, L.K.2    Elsegood, K.A.3    Speight, P.4    Scully, C.5    Prime, S.S.6
  • 191
    • 0027372049 scopus 로고
    • Immunohistochemical analysis of ras p21 expression in normal, premalignant and malignant oral mucosa
    • Kannan S, Balaram P, Radhakrishna P, Chandran GJ and Nair MK: Immunohistochemical analysis of ras p21 expression in normal, premalignant and malignant oral mucosa. Int J Cancer 55: 700-702, 1993.
    • (1993) Int J Cancer , vol.55 , pp. 700-702
    • Kannan, S.1    Balaram, P.2    Radhakrishna, P.3    Chandran, G.J.4    Nair, M.K.5
  • 192
    • 0022746134 scopus 로고
    • Clinical relevance of oncogene expression in head and neck tumours
    • Field JK, Lamothe A and Spandidos DA: Clinical relevance of oncogene expression in head and neck tumours. Anticancer Res 6: 595-600, 1986.
    • (1986) Anticancer Res , vol.6 , pp. 595-600
    • Field, J.K.1    Lamothe, A.2    Spandidos, D.A.3
  • 194
    • 0024318896 scopus 로고
    • Loss of Harvey ras heterozygosity in oral squamous cell carcinoma
    • Howell RE, Wong FSH and Fenwick RG: Loss of Harvey ras heterozygosity in oral squamous cell carcinoma. J Oral Pathol Med 18: 79-83, 1989.
    • (1989) J Oral Pathol Med , vol.18 , pp. 79-83
    • Howell, R.E.1    Wong, F.S.H.2    Fenwick, R.G.3
  • 195
    • 0026642865 scopus 로고
    • Activating mutation of the Ha-ras gene in chemically induced tumors of the hamster cheek pouch
    • Gimenez-Conti IB, Bianchi AB, Stockman SL, Conti CJ and Slaga TJ: Activating mutation of the Ha-ras gene in chemically induced tumors of the hamster cheek pouch. Mol Carcinogen 5: 259-263, 1992.
    • (1992) Mol Carcinogen , vol.5 , pp. 259-263
    • Gimenez-Conti, I.B.1    Bianchi, A.B.2    Stockman, S.L.3    Conti, C.J.4    Slaga, T.J.5
  • 196
    • 0028072696 scopus 로고
    • Harvey ras (H-ras) point mutations are induced by 4-nitroquinoline-1-oxide in murine oral squamous epithelia, while squamous cell carcinomas and loss of heterozygosity occur without additional exposure
    • Yuan B, Heniford BW, Ackermann DM, Hawkins BL and Hendler FJ: Harvey ras (H-ras) point mutations are induced by 4-nitroquinoline-1-oxide in murine oral squamous epithelia, while squamous cell carcinomas and loss of heterozygosity occur without additional exposure. Cancer Res 54: 5310-5317, 1994.
    • (1994) Cancer Res , vol.54 , pp. 5310-5317
    • Yuan, B.1    Heniford, B.W.2    Ackermann, D.M.3    Hawkins, B.L.4    Hendler, F.J.5
  • 197
    • 0023132887 scopus 로고
    • Transforming activity of human c-H-ras-1 proto-oncogene generated by the binding of 2-amino-6-methyl-dipyrido (1,2-a:3′,2′-d)imidazole and 4-nitroquinoline N-oxide: Direct evidence of cellular transformation by chemically modified DNA
    • Hashimoto Y, Kawachi E, Shudo K, Sekiya T and Sugimura T: Transforming activity of human c-H-ras-1 proto-oncogene generated by the binding of 2-amino-6-methyl-dipyrido (1,2-a:3′,2′-d)imidazole and 4-nitroquinoline N-oxide: direct evidence of cellular transformation by chemically modified DNA. Jpn J Cancer Res 78: 211-215, 1987.
    • (1987) Jpn J Cancer Res , vol.78 , pp. 211-215
    • Hashimoto, Y.1    Kawachi, E.2    Shudo, K.3    Sekiya, T.4    Sugimura, T.5
  • 200
    • 0024292712 scopus 로고
    • The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A
    • Phelps WE, Yee CL, Munger K and Howley PM: The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A. Cell 53: 539-547, 1988.
    • (1988) Cell , vol.53 , pp. 539-547
    • Phelps, W.E.1    Yee, C.L.2    Munger, K.3    Howley, P.M.4
  • 201
    • 0028370026 scopus 로고
    • Mutations of Ki-ras oncogene codon 12 in betel quid chewing-related human oral squamous cell carcinoma in Taiwan
    • Kuo MYP, Jeng JH, Chiang CP and Hahn LJ: Mutations of Ki-ras oncogene codon 12 in betel quid chewing-related human oral squamous cell carcinoma in Taiwan. J Oral Pathol Med 23: 70-74, 1994.
    • (1994) J Oral Pathol Med , vol.23 , pp. 70-74
    • Kuo, M.Y.P.1    Jeng, J.H.2    Chiang, C.P.3    Hahn, L.J.4
  • 202
    • 0028017632 scopus 로고
    • Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma
    • Yoo GH, Xu HJ, Brennan JA, Westra W, Hruban RH, Koch W, Benedict WF and Sidransky D: Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma. Cancer Res 54: 4603-4606, 1994.
    • (1994) Cancer Res , vol.54 , pp. 4603-4606
    • Yoo, G.H.1    Xu, H.J.2    Brennan, J.A.3    Westra, W.4    Hruban, R.H.5    Koch, W.6    Benedict, W.F.7    Sidransky, D.8
  • 203
    • 0027331855 scopus 로고
    • State of p53, Rb and DCC tumor suppressor genes in human oral cancer cell lines
    • Kim MS, Li S-L, Bertolami CN, Cherrick HM and Park N-H: State of p53, Rb and DCC tumor suppressor genes in human oral cancer cell lines. Anticancer Res 13: 1405-1414, 1993.
    • (1993) Anticancer Res , vol.13 , pp. 1405-1414
    • Kim, M.S.1    Li, S.-L.2    Bertolami, C.N.3    Cherrick, H.M.4    Park, N.-H.5
  • 204
    • 0027512268 scopus 로고
    • Loss of heterozygosity of p53 in oral cancers demonstrated by the polymerase chain reaction
    • Largey JS, Meltzer SJ, Yin J, et al: Loss of heterozygosity of p53 in oral cancers demonstrated by the polymerase chain reaction. Cancer 71: 1933-1937, 1993.
    • (1993) Cancer , vol.71 , pp. 1933-1937
    • Largey, J.S.1    Meltzer, S.J.2    Yin, J.3
  • 205
    • 0028606130 scopus 로고
    • Numerical aberrations of chromosome 17 detected by FISH with DNA-specific probe in oral tumours
    • Tsuji T, Mimura Y, Maeda K, Ida M, Sasaki K and Shinozaki F: Numerical aberrations of chromosome 17 detected by FISH with DNA-specific probe in oral tumours. Anticancer Res 14: 1689-1693, 1994.
    • (1994) Anticancer Res , vol.14 , pp. 1689-1693
    • Tsuji, T.1    Mimura, Y.2    Maeda, K.3    Ida, M.4    Sasaki, K.5    Shinozaki, F.6
  • 207
    • 0028303944 scopus 로고
    • Loss of heterozygosity studies on chromosome 17 in head and neck cancer using microsatellite markers
    • Adamson R, Jones AS and Field JK: Loss of heterozygosity studies on chromosome 17 in head and neck cancer using microsatellite markers. Oncogene 9: 2077-2092, 1994.
    • (1994) Oncogene , vol.9 , pp. 2077-2092
    • Adamson, R.1    Jones, A.S.2    Field, J.K.3
  • 208
    • 0026793914 scopus 로고
    • Oral cancer progression and c-erbB-2/neu proto-oncogene expression
    • Hou L, Shi D, Tu S-M, et al: Oral cancer progression and c-erbB-2/neu proto-oncogene expression. Cancer Lett 65: 215-220, 1992.
    • (1992) Cancer Lett , vol.65 , pp. 215-220
    • Hou, L.1    Shi, D.2    Tu, S.-M.3
  • 209
    • 0027055481 scopus 로고
    • Expression of c-erbB-2 in human head and neck carcinoma
    • Craven JM, Pavelic ZP, Stambrook PJ, et al: Expression of c-erbB-2 in human head and neck carcinoma. Anticancer Res 12: 2273-2276, 1992.
    • (1992) Anticancer Res , vol.12 , pp. 2273-2276
    • Craven, J.M.1    Pavelic, Z.P.2    Stambrook, P.J.3
  • 210
    • 0026759018 scopus 로고
    • C-erbB-2 expression in squamous cell carcinoma of the head and neck
    • Field JK, Spandidos DA, Yiagnisis M, et al: C-erbB-2 expression in squamous cell carcinoma of the head and neck. Anticancer Res 12: 613-619, 1992.
    • (1992) Anticancer Res , vol.12 , pp. 613-619
    • Field, J.K.1    Spandidos, D.A.2    Yiagnisis, M.3
  • 211
    • 0029005367 scopus 로고
    • Prognostic relevance of aberrations in the erbB oncogenes from breast, ovarian, oral and lung cancers: Double-differential polymerase chain reaction (ddPCR) for clinical diagnosis
    • Brandt B, Vogt Y, Schlotter CM, et al: Prognostic relevance of aberrations in the erbB oncogenes from breast, ovarian, oral and lung cancers: double-differential polymerase chain reaction (ddPCR) for clinical diagnosis. Gene 159: 35-42, 1995.
    • (1995) Gene , vol.159 , pp. 35-42
    • Brandt, B.1    Vogt, Y.2    Schlotter, C.M.3
  • 212
    • 0028903165 scopus 로고
    • p53 expression: A potential biomarker for risk of multiple primary malignancies in the upper aerodigestive tract
    • Gallo O and Bianchi S: p53 expression: a potential biomarker for risk of multiple primary malignancies in the upper aerodigestive tract. Oral Oncol Eur J Cancer 31B: 53-57, 1995.
    • (1995) Oral Oncol Eur J Cancer , vol.31 B , pp. 53-57
    • Gallo, O.1    Bianchi, S.2
  • 213
    • 0028454180 scopus 로고
    • The yin and yang of p53 in cellular proliferation
    • Deppert W: The yin and yang of p53 in cellular proliferation. Cancer Biol 5: 187-202, 1994.
    • (1994) Cancer Biol , vol.5 , pp. 187-202
    • Deppert, W.1
  • 214
    • 0028605343 scopus 로고
    • New link found between p53 and DNA repair
    • Marx J: New link found between p53 and DNA repair. Science 266: 1321-1322, 1994.
    • (1994) Science , vol.266 , pp. 1321-1322
    • Marx, J.1
  • 216
    • 0027716315 scopus 로고
    • p53 sweeps through cancer research
    • Culotta E and Koshland DE Jr: p53 sweeps through cancer research. Science 262: 1958-1961, 1993.
    • (1993) Science , vol.262 , pp. 1958-1961
    • Culotta, E.1    Koshland Jr., D.E.2
  • 217
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M and Harris CC: Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54: 4855-4878, 1994.
    • (1994) Cancer Res , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 221
    • 0028206590 scopus 로고
    • Frameshift and nonsense p53 mutations in squamous cell carcinoma of head and neck: Non-reactivity with three anti-p53 monoclonal antibodies
    • Chen YT, Xu L, Massey L, Zlotolow IM, Huvos AG, Garin-Chesa P and Old LJ: Frameshift and nonsense p53 mutations in squamous cell carcinoma of head and neck: non-reactivity with three anti-p53 monoclonal antibodies. Int J Oncol 4: 609-614, 1994.
    • (1994) Int J Oncol , vol.4 , pp. 609-614
    • Chen, Y.T.1    Xu, L.2    Massey, L.3    Zlotolow, I.M.4    Huvos, A.G.5    Garin-Chesa, P.6    Old, L.J.7
  • 222
    • 0027717991 scopus 로고
    • Some oral carcinoma from Sri Lanka betel/tobacco chewers overexpress p53 oncoprotein but lack mutations in exons 5-9
    • Ranasinghe A, MacGeoch C, Dyer S, Spurr N and Johnson NW: Some oral carcinoma from Sri Lanka betel/tobacco chewers overexpress p53 oncoprotein but lack mutations in exons 5-9. Anticancer Res 13: 2065-2068, 1993.
    • (1993) Anticancer Res , vol.13 , pp. 2065-2068
    • Ranasinghe, A.1    MacGeoch, C.2    Dyer, S.3    Spurr, N.4    Johnson, N.W.5
  • 223
    • 0027285474 scopus 로고
    • Low prevalence of expression of p53 oncoprotein in oral carcinomas from Sri Lanka associated with betel and tobacco chewing
    • Ranasinghe AW, Warnakulasuriya KAAS and Johnson NW: Low prevalence of expression of p53 oncoprotein in oral carcinomas from Sri Lanka associated with betel and tobacco chewing. Oral Oncol Eur J Cancer 29B: 147-150, 1993.
    • (1993) Oral Oncol Eur J Cancer , vol.29 B , pp. 147-150
    • Ranasinghe, A.W.1    Warnakulasuriya, K.A.A.S.2    Johnson, N.W.3
  • 225
    • 0030087692 scopus 로고    scopus 로고
    • The use of antigen retrieval for immunohistochemical detection of p53 overexpression in malignant and benign oral mucosa: A cautionary tale
    • Dowell SP and Ogden GR: The use of antigen retrieval for immunohistochemical detection of p53 overexpression in malignant and benign oral mucosa: a cautionary tale. J Oral Pathol Med 25: 60-64, 1996.
    • (1996) J Oral Pathol Med , vol.25 , pp. 60-64
    • Dowell, S.P.1    Ogden, G.R.2
  • 226
    • 0025738297 scopus 로고
    • Elevated p53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck
    • Field JK, Spandidos DA, Malliri A, Yiagnisis M, Gosney JR and Stell PM: Elevated p53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck. Br J Cancer 64: 573-577, 1991.
    • (1991) Br J Cancer , vol.64 , pp. 573-577
    • Field, J.K.1    Spandidos, D.A.2    Malliri, A.3    Yiagnisis, M.4    Gosney, J.R.5    Stell, P.M.6
  • 227
    • 0025941313 scopus 로고
    • Expression of p53 in premalignant and malignant squamous epithelium
    • Gusterson BA, Anbazaghan R, Warren W, et al: Expression of p53 in premalignant and malignant squamous epithelium. Oncogene 6: 1785-1789, 1991.
    • (1991) Oncogene , vol.6 , pp. 1785-1789
    • Gusterson, B.A.1    Anbazaghan, R.2    Warren, W.3
  • 229
    • 0027099684 scopus 로고
    • Detection of mutations in p53 gene in human head and neck carcinomas by single strand conformation polymorphism analysis
    • Chang Y, Lin Y, Tsai C, Shu C, Tsai M, Choo K and Liu S: Detection of mutations in p53 gene in human head and neck carcinomas by single strand conformation polymorphism analysis. Cancer Lett 67: 167-174, 1992.
    • (1992) Cancer Lett , vol.67 , pp. 167-174
    • Chang, Y.1    Lin, Y.2    Tsai, C.3    Shu, C.4    Tsai, M.5    Choo, K.6    Liu, S.7
  • 230
    • 0026598768 scopus 로고
    • Overexpression of the p53 gene in head and neck cancer, linked with heavy smoking and drinking
    • Field JK, Spandidos DA and Stell PM: Overexpression of the p53 gene in head and neck cancer, linked with heavy smoking and drinking. Lancet 339: 502-503, 1992.
    • (1992) Lancet , vol.339 , pp. 502-503
    • Field, J.K.1    Spandidos, D.A.2    Stell, P.M.3
  • 231
    • 0343608130 scopus 로고
    • Mutations in the p53 gene at codon 249 are rare in squamous cell carcinoma of the head and neck
    • Field JK, Malliri A, Jones AJ and Spandidos DA: Mutations in the p53 gene at codon 249 are rare in squamous cell carcinoma of the head and neck. Int J Oncol 1: 253-256, 1992.
    • (1992) Int J Oncol , vol.1 , pp. 253-256
    • Field, J.K.1    Malliri, A.2    Jones, A.J.3    Spandidos, D.A.4
  • 232
    • 0026763465 scopus 로고
    • Expression of the tumour suppressor gene p53 in oral cancer
    • Langdon JD and Partridge M: Expression of the tumour suppressor gene p53 in oral cancer. Brit J Oral Maxillofac Surg 30: 214-220, 1992.
    • (1992) Brit J Oral Maxillofac Surg , vol.30 , pp. 214-220
    • Langdon, J.D.1    Partridge, M.2
  • 233
    • 0026534598 scopus 로고
    • Assessment of p53 protein expression in normal, benign and malignant oral mucosa
    • Ogden GR, Kiddie RA, Lunny DP and Lane DP: Assessment of p53 protein expression in normal, benign and malignant oral mucosa. J Pathol 166: 389-394, 1992.
    • (1992) J Pathol , vol.166 , pp. 389-394
    • Ogden, G.R.1    Kiddie, R.A.2    Lunny, D.P.3    Lane, D.P.4
  • 234
    • 0026487126 scopus 로고
    • Improved immunohistochemical detection of p53 protein in paraffin-embedded tissues reveals elevated levels in most head and neck and lung carcinomas: Correlation of clinicopathological parameters
    • Pavelic Z, Gluckman J, Gapany M, Reising J, Craven J, Kelley D, Pavelic L, Gapany S, Biddinger P and Strambrook P: Improved immunohistochemical detection of p53 protein in paraffin-embedded tissues reveals elevated levels in most head and neck and lung carcinomas: correlation of clinicopathological parameters. Anticancer Res 12: 1389-1394, 1992.
    • (1992) Anticancer Res , vol.12 , pp. 1389-1394
    • Pavelic, Z.1    Gluckman, J.2    Gapany, M.3    Reising, J.4    Craven, J.5    Kelley, D.6    Pavelic, L.7    Gapany, S.8    Biddinger, P.9    Strambrook, P.10
  • 235
    • 0026620901 scopus 로고
    • The p53 tumour suppressor gene and ras oncogene mutations in oral squamous cell carcinoma
    • Sakai E, Rikimura K, Ueda M, et al: The p53 tumour suppressor gene and ras oncogene mutations in oral squamous cell carcinoma. Int J Cancer 52: 729-867, 1992.
    • (1992) Int J Cancer , vol.52 , pp. 729-867
    • Sakai, E.1    Rikimura, K.2    Ueda, M.3
  • 237
    • 0026560020 scopus 로고
    • Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes
    • Sakai E and Tsuchida N: Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes. Oncogene 7: 927-933, 1992.
    • (1992) Oncogene , vol.7 , pp. 927-933
    • Sakai, E.1    Tsuchida, N.2
  • 238
    • 0030046066 scopus 로고    scopus 로고
    • P53 overexpression in head and neck carcinoma and radiotherapy results
    • Awwad S, Jaras E, Somes J, Lunec J: P53 overexpression in head and neck carcinoma and radiotherapy results. Int J Radiation Biol Phys 34: 323-332, 1996.
    • (1996) Int J Radiation Biol Phys , vol.34 , pp. 323-332
    • Awwad, S.1    Jaras, E.2    Somes, J.3    Lunec, J.4
  • 240
    • 0026768143 scopus 로고
    • Overexpression of p53 in head and neck cancer
    • Watling DL, Gown AM and Coltrera MD: Overexpression of p53 in head and neck cancer. Head Neck 14: 437-444, 1992.
    • (1992) Head Neck , vol.14 , pp. 437-444
    • Watling, D.L.1    Gown, A.M.2    Coltrera, M.D.3
  • 241
    • 0027892066 scopus 로고
    • p53 protein expression in squamocellular carcinomas of the lip
    • Berner A, Holm R, Naess A and Hjortdal O: p53 protein expression in squamocellular carcinomas of the lip. Anticancer Res 13: 2421-2424, 1993.
    • (1993) Anticancer Res , vol.13 , pp. 2421-2424
    • Berner, A.1    Holm, R.2    Naess, A.3    Hjortdal, O.4
  • 243
    • 0027415517 scopus 로고
    • Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract
    • Chung KY, Mukhopadyay T, Kim J, Casson A, Ro JY, Goepfert H, Hong WK and Roth JA: Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract. Cancer Res 53: 1676-1683, 1993.
    • (1993) Cancer Res , vol.53 , pp. 1676-1683
    • Chung, K.Y.1    Mukhopadyay, T.2    Kim, J.3    Casson, A.4    Ro, J.Y.5    Goepfert, H.6    Hong, W.K.7    Roth, J.A.8
  • 244
    • 0027295824 scopus 로고
    • P53 overexpression in end stage squamous cell carcinomas of the head and neck: Correlates with a very poor clinical outcome
    • Field JK, Malliri A, Butt SA, et al: p53 overexpression in end stage squamous cell carcinomas of the head and neck: correlates with a very poor clinical outcome. Int J Oncol 3: 431-435, 1993.
    • (1993) Int J Oncol , vol.3 , pp. 431-435
    • Field, J.K.1    Malliri, A.2    Butt, S.A.3
  • 246
    • 0027367016 scopus 로고
    • Immunohistochemical detection of p53 oncoprotein in human oral squamous cell carcinomas and leukoplakias: Comparison with proliferating cell nuclear antigen staining and correlation with clinicopathological findings
    • Nishioka H, Hiasa Y, Isao H, Yoshiteru K, Kitahori Y, Konishi N and Sugimura M: Immunohistochemical detection of p53 oncoprotein in human oral squamous cell carcinomas and leukoplakias: comparison with proliferating cell nuclear antigen staining and correlation with clinicopathological findings. Oncology 50: 426-429, 1993.
    • (1993) Oncology , vol.50 , pp. 426-429
    • Nishioka, H.1    Hiasa, Y.2    Isao, H.3    Yoshiteru, K.4    Kitahori, Y.5    Konishi, N.6    Sugimura, M.7
  • 247
    • 0027315554 scopus 로고
    • Abnormalities in the p53 gene in tumors and cell lines of human squamous-cell carcinomas of the head and neck
    • Yin XY, Smith ML, Whiteside TL, Johnson JT, Herberman AB and Locker J: Abnormalities in the p53 gene in tumors and cell lines of human squamous-cell carcinomas of the head and neck. Int J Cancer 54: 322-327, 1993.
    • (1993) Int J Cancer , vol.54 , pp. 322-327
    • Yin, X.Y.1    Smith, M.L.2    Whiteside, T.L.3    Johnson, J.T.4    Herberman, A.B.5    Locker, J.6
  • 249
    • 0028048423 scopus 로고
    • Nuclear DNA content and p53 immunostaining in oral squamous cell carcinoma - An analysis of a consecutive 10 year material
    • Högmo A, Munck-Wikland E, Kuylenstierna R, Lindholm J and Auer G: Nuclear DNA content and p53 immunostaining in oral squamous cell carcinoma - an analysis of a consecutive 10 year material. Int J Oncol 5: 915-920, 1994.
    • (1994) Int J Oncol , vol.5 , pp. 915-920
    • Högmo, A.1    Munck-Wikland, E.2    Kuylenstierna, R.3    Lindholm, J.4    Auer, G.5
  • 251
    • 0028031138 scopus 로고
    • Prognostic significance of p53 protein accumulation in early stage T1 oral cavity cancer
    • Gluckman JL, Stambrook PJ and Pavelic ZP: Prognostic significance of p53 protein accumulation in early stage T1 oral cavity cancer. Oral Oncol Eur J Cancer 30B: 281, 1994.
    • (1994) Oral Oncol Eur J Cancer , vol.30 B , pp. 281
    • Gluckman, J.L.1    Stambrook, P.J.2    Pavelic, Z.P.3
  • 252
    • 0028158007 scopus 로고
    • Activation of p53 gene expression in premalignant lesions during head and neck tumonigenesis
    • Shin DM, Kim J, Ro JY, Hittelman J, Roth JA, Hong WK and Hittelman WN: Activation of p53 gene expression in premalignant lesions during head and neck tumonigenesis. Cancer Res 54: 321-326, 1994.
    • (1994) Cancer Res , vol.54 , pp. 321-326
    • Shin, D.M.1    Kim, J.2    Ro, J.Y.3    Hittelman, J.4    Roth, J.A.5    Hong, W.K.6    Hittelman, W.N.7
  • 253
    • 0028174225 scopus 로고
    • p53 gene mutations in oropharyngeal carcinomas: A comparison of solitary and multiple primary tumours and lymph-node metastases
    • Zariwala M, Schmid S, Pfaltz M, Ohgaki H, Kleihues P and Schafer R: p53 gene mutations in oropharyngeal carcinomas: a comparison of solitary and multiple primary tumours and lymph-node metastases. Int J Cancer 56: 807-811, 1994.
    • (1994) Int J Cancer , vol.56 , pp. 807-811
    • Zariwala, M.1    Schmid, S.2    Pfaltz, M.3    Ohgaki, H.4    Kleihues, P.5    Schafer, R.6
  • 255
    • 0028814029 scopus 로고
    • Molecular assessment of histopathological staging in squamous cell carcinoma of the head and neck
    • Brennan JA, Mao L, Hruban RH, Boyle JO, et al: Molecular assessment of histopathological staging in squamous cell carcinoma of the head and neck. N Engl J Med 332: 429-435, 1995.
    • (1995) N Engl J Med , vol.332 , pp. 429-435
    • Brennan, J.A.1    Mao, L.2    Hruban, R.H.3    Boyle, J.O.4
  • 256
    • 0028931590 scopus 로고
    • Immunohistochemical detection of p53 protein in preneoplastic lesions and squamous cell carcinoma of the head and neck
    • Lavieille JP, Brabilla E, Riva-Lavieille C, Reyt E, Charachon R and Brambilla C: Immunohistochemical detection of p53 protein in preneoplastic lesions and squamous cell carcinoma of the head and neck. Acta Oto-laryngol 115: 334-339, 1995.
    • (1995) Acta Oto-laryngol , vol.115 , pp. 334-339
    • Lavieille, J.P.1    Brabilla, E.2    Riva-Lavieille, C.3    Reyt, E.4    Charachon, R.5    Brambilla, C.6
  • 257
    • 0028838610 scopus 로고
    • TP53 mutations in upper aerodigestive squamous cell carciomas from a group of Brazilian patients
    • Nagai MA, Miracca EC, Yamamoto L, Kowalski LP and Brentani RR: TP53 mutations in upper aerodigestive squamous cell carciomas from a group of Brazilian patients. Am J Surg 170: 492-494, 1995.
    • (1995) Am J Surg , vol.170 , pp. 492-494
    • Nagai, M.A.1    Miracca, E.C.2    Yamamoto, L.3    Kowalski, L.P.4    Brentani, R.R.5
  • 258
    • 0028842503 scopus 로고
    • Recurrences and second primary tumours in the head and neck region: Differentiation by p53 mutation analysis
    • Gasparotto D, Maestro R, Barzan L, et al: Recurrences and second primary tumours in the head and neck region: differentiation by p53 mutation analysis. Ann Oncol 6: 933-939, 1995.
    • (1995) Ann Oncol , vol.6 , pp. 933-939
    • Gasparotto, D.1    Maestro, R.2    Barzan, L.3
  • 259
    • 0029046901 scopus 로고
    • Overexpression of p53 is an early event in the tumorigenesis of oral squamous cell carcinomas
    • Shintani S, Yoshihama Y, Emilio AR and MatsumuraT: Overexpression of p53 is an early event in the tumorigenesis of oral squamous cell carcinomas. Anticancer Res 15: 205-208, 1995.
    • (1995) Anticancer Res , vol.15 , pp. 205-208
    • Shintani, S.1    Yoshihama, Y.2    Emilio, A.R.3    Matsumura, T.4
  • 260
    • 15844389852 scopus 로고    scopus 로고
    • P53 gene alterations and p53 protein in oral epithelial dysplasia and squamous cell carcinoma
    • Kusama K, Okutsu S, Takeda A, et al: P53 gene alterations and p53 protein in oral epithelial dysplasia and squamous cell carcinoma. J Pathol 178: 415-421, 1996.
    • (1996) J Pathol , vol.178 , pp. 415-421
    • Kusama, K.1    Okutsu, S.2    Takeda, A.3
  • 261
    • 0029923259 scopus 로고    scopus 로고
    • Relationship between p53 mutation incidence in oral cavity squamous cell carcinomas and patient tobacco use
    • Lazarus P, Stern J, Zwiebel N, Fair A, Richie JP Jr and Schantz S: Relationship between p53 mutation incidence in oral cavity squamous cell carcinomas and patient tobacco use. Carcinogenesis 17: 733-739, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 733-739
    • Lazarus, P.1    Stern, J.2    Zwiebel, N.3    Fair, A.4    Richie Jr., J.P.5    Schantz, S.6
  • 264
    • 0030087886 scopus 로고    scopus 로고
    • Overexpression of p53 protein in squamous cell carcinoma of buccal mucosa and tongue in Taiwan: An immunohistochemical and clinicopathological study
    • Yan JJ, Tzeng CC and Jin YT: Overexpression of p53 protein in squamous cell carcinoma of buccal mucosa and tongue in Taiwan: an immunohistochemical and clinicopathological study. J Oral Pathol Med 25: 55-59, 1996.
    • (1996) J Oral Pathol Med , vol.25 , pp. 55-59
    • Yan, J.J.1    Tzeng, C.C.2    Jin, Y.T.3
  • 265
    • 0028467172 scopus 로고
    • Association of overexpression of p53 oncoprotein with the state of cell proliferation in oral carcinoma
    • Warnakulasuriya KAAS and Johnson NW: Association of overexpression of p53 oncoprotein with the state of cell proliferation in oral carcinoma. J Oral Pathol Med 23: 246-250, 1994.
    • (1994) J Oral Pathol Med , vol.23 , pp. 246-250
    • Warnakulasuriya, K.A.A.S.1    Johnson, N.W.2
  • 266
    • 0026490218 scopus 로고
    • Expression of the tumour suppressor gene p53 mutant nuclear phosphoprotein in oral carcinoma and potentially malignant oral lesions
    • Warnakulasuriya KAAS and Johnson NW: Expression of the tumour suppressor gene p53 mutant nuclear phosphoprotein in oral carcinoma and potentially malignant oral lesions. J Oral Pathol Med 21: 404-408, 1992.
    • (1992) J Oral Pathol Med , vol.21 , pp. 404-408
    • Warnakulasuriya, K.A.A.S.1    Johnson, N.W.2
  • 267
    • 0027438521 scopus 로고
    • p53 and Ki-67 expression in preneoplastic and neoplastic lesions of the oral mucosa
    • Girod SC, Krueger G and Paper HD: p53 and Ki-67 expression in preneoplastic and neoplastic lesions of the oral mucosa. Int J Oral Maxillofac Surg 22: 285-288, 1993.
    • (1993) Int J Oral Maxillofac Surg , vol.22 , pp. 285-288
    • Girod, S.C.1    Krueger, G.2    Paper, H.D.3
  • 268
    • 0027853193 scopus 로고
    • Expression of mutated p53 occurs in tumor-distant epithelia of head and neck cancer patients: A possible molecular basis for the development of multiple tumors
    • Nees M, Homann N, Discher H, Andl T, Enders C, Harrold-Mende C, Schulmann A and Bosch FX: Expression of mutated p53 occurs in tumor-distant epithelia of head and neck cancer patients: a possible molecular basis for the development of multiple tumors. Cancer Res 53: 4189-4196, 1993.
    • (1993) Cancer Res , vol.53 , pp. 4189-4196
    • Nees, M.1    Homann, N.2    Discher, H.3    Andl, T.4    Enders, C.5    Harrold-Mende, C.6    Schulmann, A.7    Bosch, F.X.8
  • 269
    • 0028106313 scopus 로고
    • Overexpression of p53 protein in betel- and tobacco-related human oral dysplasia and squamous cell carcinoma in India
    • Kaur J, Srivastava A and Ralhan R: Overexpression of p53 protein in betel- and tobacco-related human oral dysplasia and squamous cell carcinoma in India. Int J Cancer 58: 240-245, 1994.
    • (1994) Int J Cancer , vol.58 , pp. 240-245
    • Kaur, J.1    Srivastava, A.2    Ralhan, R.3
  • 270
    • 0028113633 scopus 로고
    • p53 is overexpressed in fifty percent of pre-invasive lesions of head and neck epithelium
    • Sauter ER, Cleveland D, Trock B, Ridge JA and Klein-Szanto JP: p53 is overexpressed in fifty percent of pre-invasive lesions of head and neck epithelium. Carcinogenesis 15: 2269-2274, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 2269-2274
    • Sauter, E.R.1    Cleveland, D.2    Trock, B.3    Ridge, J.A.4    Klein-Szanto, J.P.5
  • 271
    • 0028347978 scopus 로고
    • The presence of p53 protein in relation to Ki-67 as cellular proliferation marker in head and neck squamous cell carcinoma and adjacent dysplastic mucosa
    • Slootweg PJ, Koole R and Hordijk GJ: The presence of p53 protein in relation to Ki-67 as cellular proliferation marker in head and neck squamous cell carcinoma and adjacent dysplastic mucosa. Oral Oncol Eur J Cancer 30B: 138-141, 1994.
    • (1994) Oral Oncol Eur J Cancer , vol.30 B , pp. 138-141
    • Slootweg, P.J.1    Koole, R.2    Hordijk, G.J.3
  • 276
    • 0029664754 scopus 로고    scopus 로고
    • P53 expression: Predicting recurrence and second primary tumors in head and neck squamous cell carcinoma
    • Shin DM, Lee JS, Lippman SM, et al: P53 expression: predicting recurrence and second primary tumors in head and neck squamous cell carcinoma. J Natl Cancer Inst 88: 519-529, 1996.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 519-529
    • Shin, D.M.1    Lee, J.S.2    Lippman, S.M.3
  • 277
    • 0027022218 scopus 로고
    • p53 Overexpression correlates with increased survival in patients with squamous carcinoma of the tongue base
    • Sauter ER, Ridge JA, Gordon J and Elsenberg BL: p53 Overexpression correlates with increased survival in patients with squamous carcinoma of the tongue base. Am J Surg 164: 651-653, 1992.
    • (1992) Am J Surg , vol.164 , pp. 651-653
    • Sauter, E.R.1    Ridge, J.A.2    Gordon, J.3    Elsenberg, B.L.4
  • 278
    • 0027350156 scopus 로고
    • Relationship between immunohistochemically detectable p53 protein and prognostic factors in head and neck tumors
    • Gapany M, Pavelic ZP, Gapany SR, et al: Relationship between immunohistochemically detectable p53 protein and prognostic factors in head and neck tumors. Cancer Detection Prev 17: 379-386, 1993.
    • (1993) Cancer Detection Prev , vol.17 , pp. 379-386
    • Gapany, M.1    Pavelic, Z.P.2    Gapany, S.R.3
  • 279
    • 0028052266 scopus 로고
    • Tumor angiogenesis, the p53 antigen and cervical metastasis in squamous cell carcinoma of the tongue
    • Leedy DA, Trune DR, Kronz JD, Weidner N and Cohen JI: Tumor angiogenesis, the p53 antigen and cervical metastasis in squamous cell carcinoma of the tongue. Otolaryngol Head Neck Surg 111: 417-422, 1994.
    • (1994) Otolaryngol Head Neck Surg , vol.111 , pp. 417-422
    • Leedy, D.A.1    Trune, D.R.2    Kronz, J.D.3    Weidner, N.4    Cohen, J.I.5
  • 280
    • 0028072009 scopus 로고
    • Association of p53 expression with cytokinetics and HPV capsid antigen prevalence in oral carcinomas
    • Mukhopadhyay D, Chatterjee R and Chakraborty RN: Association of p53 expression with cytokinetics and HPV capsid antigen prevalence in oral carcinomas. Cancer Lett 87: 99-105, 1994.
    • (1994) Cancer Lett , vol.87 , pp. 99-105
    • Mukhopadhyay, D.1    Chatterjee, R.2    Chakraborty, R.N.3
  • 281
    • 0028359148 scopus 로고
    • Die expression der tumor suppressorgene p53 und Rb bei patienten mit plattenepihtelkarzinomen im Kopf/Halsbereich
    • Schipper JH and Kelker W: Die expression der tumor suppressorgene p53 und Rb bei patienten mit plattenepihtelkarzinomen im Kopf/Halsbereich. HNO 42: 270-274, 1994.
    • (1994) HNO , vol.42 , pp. 270-274
    • Schipper, J.H.1    Kelker, W.2
  • 282
    • 0027997635 scopus 로고
    • TP53 gene mutations and CCND1 gene amplification in head and neck squamous cell carcinoma lines
    • Xu L, Davidson BJ, Murty VVVS, et al: TP53 gene mutations and CCND1 gene amplification in head and neck squamous cell carcinoma lines. Int J Cancer 59: 383-387, 1994.
    • (1994) Int J Cancer , vol.59 , pp. 383-387
    • Xu, L.1    Davidson, B.J.2    Murty, V.V.V.S.3
  • 283
    • 0028951290 scopus 로고
    • High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumours and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions
    • Ahomadegbe JC, Barrois M, Fogel S, et al: High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumours and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions. Oncogene 10: 1217-1227, 1995.
    • (1995) Oncogene , vol.10 , pp. 1217-1227
    • Ahomadegbe, J.C.1    Barrois, M.2    Fogel, S.3
  • 284
    • 0028985726 scopus 로고
    • p53 expression in multicentric squamous cell carcinoma and surrounding squamous epithelium of the upper aerodigestive tract
    • Nakanishi Y, Noguchi M, Matsuno Y, Saikawa M, Mukai K, Shimosato Y and Hirohashi S: p53 expression in multicentric squamous cell carcinoma and surrounding squamous epithelium of the upper aerodigestive tract. Cancer 75: 1657-1662, 1995.
    • (1995) Cancer , vol.75 , pp. 1657-1662
    • Nakanishi, Y.1    Noguchi, M.2    Matsuno, Y.3    Saikawa, M.4    Mukai, K.5    Shimosato, Y.6    Hirohashi, S.7
  • 285
    • 0028832048 scopus 로고
    • p53 expression and cell proliferation in squamous cell carcinomas of the head and neck
    • Nylander K, Stenling R, Gustafsson H, Zackrisson B and Roos G: p53 expression and cell proliferation in squamous cell carcinomas of the head and neck. Cancer 75: 87-93, 1995.
    • (1995) Cancer , vol.75 , pp. 87-93
    • Nylander, K.1    Stenling, R.2    Gustafsson, H.3    Zackrisson, B.4    Roos, G.5
  • 286
    • 0028953618 scopus 로고
    • p53 mutations, protein expression and cell proliferation in squamous cell carcinomas of the head and neck
    • Nylander K, Nilsson P, Mehle C and Roos G: p53 mutations, protein expression and cell proliferation in squamous cell carcinomas of the head and neck. Cancer 71: 826-830, 1995.
    • (1995) Cancer , vol.71 , pp. 826-830
    • Nylander, K.1    Nilsson, P.2    Mehle, C.3    Roos, G.4
  • 287
    • 0027437509 scopus 로고
    • Intratumoral microvessel density and p53 protein: Correlation with metastasis in head and neck squamous cells carcinoma
    • Gasparini G, Weidnere N, Maluta S, et al: Intratumoral microvessel density and p53 protein: correlation with metastasis in head and neck squamous cells carcinoma. Int J Cancer 55: 739-744, 1993.
    • (1993) Int J Cancer , vol.55 , pp. 739-744
    • Gasparini, G.1    Weidnere, N.2    Maluta, S.3
  • 288
    • 0027176479 scopus 로고
    • p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines
    • Brachman DG, Beckett M, Graves D, Haraf D, Vokes E and Weichselbaum RR: p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines. Cancer Res 53: 3667-3669, 1993.
    • (1993) Cancer Res , vol.53 , pp. 3667-3669
    • Brachman, D.G.1    Beckett, M.2    Graves, D.3    Haraf, D.4    Vokes, E.5    Weichselbaum, R.R.6
  • 289
    • 0029981574 scopus 로고    scopus 로고
    • Increased radiosensitivity is associated with p53 mutations in cell lines derived from oral cavity carcinoma
    • Pekkola-Heino K, Servomaa K, Kiuru A and Grenman R: Increased radiosensitivity is associated with p53 mutations in cell lines derived from oral cavity carcinoma. Acta Oto-laryngol 116: 3341-3344, 1996.
    • (1996) Acta Oto-laryngol , vol.116 , pp. 3341-3344
    • Pekkola-Heino, K.1    Servomaa, K.2    Kiuru, A.3    Grenman, R.4
  • 292
    • 0030095683 scopus 로고
    • Incidence elevee des mutations p53 dans les tumeurs primitives et metastases dei voies aerodigestives superieures et frequente en proteine dans les epitheliums normaux
    • Fogel S, Ahomadegbe JC, Barrois M, et al: Incidence elevee des mutations p53 dans les tumeurs primitives et metastases dei voies aerodigestives superieures et frequente en proteine dans les epitheliums normaux. Bull Cancer 83: 227-233, 1956.
    • (1956) Bull Cancer , vol.83 , pp. 227-233
    • Fogel, S.1    Ahomadegbe, J.C.2    Barrois, M.3
  • 293
    • 0027269712 scopus 로고
    • Sequential upregulation of proliferating cell nucler antigen in head and neck tumorigenesis: A potential biomarker
    • Shin DM, Voravud N, Ro JY, Lee JS, Hong WK and Hitteiman WK: Sequential upregulation of proliferating cell nucler antigen in head and neck tumorigenesis: a potential biomarker. J Natl Cancer Inst 85: 971-978, 1993.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 971-978
    • Shin, D.M.1    Voravud, N.2    Ro, J.Y.3    Lee, J.S.4    Hong, W.K.5    Hitteiman, W.K.6
  • 294
    • 0028305672 scopus 로고
    • Mutations in the conserved region's of p53 are infrequent in betel-associated oral cancers from Papua New Guinea
    • Thomas S, Brennan J, Martel G, Frazer I, Montesano R, Sidransky D and Hollstein M: Mutations in the conserved region's of p53 are infrequent in betel-associated oral cancers from Papua New Guinea. Cancer Res 54: 3588-3593, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3588-3593
    • Thomas, S.1    Brennan, J.2    Martel, G.3    Frazer, I.4    Montesano, R.5    Sidransky, D.6    Hollstein, M.7
  • 295
    • 0028989718 scopus 로고
    • p53 oncoprotein overexpression correlates with mutagen-induced chromosome fragility in head and neck cancer patients with multiple malignancies
    • Gallo O, Bianchi S, Giovannucci-Uzzielli ML, Santoro R, Lenzi S, Salimbeni C, Abruzzese M and Alajmo E: p53 oncoprotein overexpression correlates with mutagen-induced chromosome fragility in head and neck cancer patients with multiple malignancies. Br J Cancer 71: 1008-1012, 1995.
    • (1995) Br J Cancer , vol.71 , pp. 1008-1012
    • Gallo, O.1    Bianchi, S.2    Giovannucci-Uzzielli, M.L.3    Santoro, R.4    Lenzi, S.5    Salimbeni, C.6    Abruzzese, M.7    Alajmo, E.8
  • 296
    • 0028041859 scopus 로고
    • P53 expression and mutations in squamous cell carcinoma of the head and neck: Expression correlates with the patients use of tobacco and alcohol
    • Field JK, Zoumpourlis V, Spandidos DA and Jones AS: P53 expression and mutations in squamous cell carcinoma of the head and neck: expression correlates with the patients use of tobacco and alcohol. Cancer Detection Prev 18: 197-208, 1994.
    • (1994) Cancer Detection Prev , vol.18 , pp. 197-208
    • Field, J.K.1    Zoumpourlis, V.2    Spandidos, D.A.3    Jones, A.S.4
  • 297
    • 0028968306 scopus 로고
    • Analysis of the p53 gene in relation to tobacco and alcohol in cancers of the upper aerodigestive tract
    • Franceschi S, Gloghini A, Maestro R, et al: Analysis of the p53 gene in relation to tobacco and alcohol in cancers of the upper aerodigestive tract. Int J Cancer 60: 872-876, 1995.
    • (1995) Int J Cancer , vol.60 , pp. 872-876
    • Franceschi, S.1    Gloghini, A.2    Maestro, R.3
  • 298
    • 0021701330 scopus 로고
    • Formation of DNA modifications by chemical carcinogens, identification, localization and quantification
    • Kriek E, Engelse LD, Scherer E and Westra JG: Formation of DNA modifications by chemical carcinogens, identification, localization and quantification. Biochem Biophys Acta 738: 181-201, 1984.
    • (1984) Biochem Biophys Acta , vol.738 , pp. 181-201
    • Kriek, E.1    Engelse, L.D.2    Scherer, E.3    Westra, J.G.4
  • 300
    • 0027386274 scopus 로고
    • p53, retinoblastoma and human papillomavirus in squamous cell carcinoma and adjacent normal mucosa of the upper aerodigestive tract
    • Lee NK, Ye Y-W, Chen J, Li X, Waber PG and Nisen PD: p53, retinoblastoma and human papillomavirus in squamous cell carcinoma and adjacent normal mucosa of the upper aerodigestive tract. Arch Otolaryngol Head Neck Surg 119: 1125-1131, 1991.
    • (1991) Arch Otolaryngol Head Neck Surg , vol.119 , pp. 1125-1131
    • Lee, N.K.1    Ye, Y.-W.2    Chen, J.3    Li, X.4    Waber, P.G.5    Nisen, P.D.6
  • 301
    • 0027079358 scopus 로고
    • The transcriptional function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein
    • Mietz JA, Unger T, Hubregtse JM and Howley PM: The transcriptional function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J 11: 5013-5020, 1992.
    • (1992) EMBO J , vol.11 , pp. 5013-5020
    • Mietz, J.A.1    Unger, T.2    Hubregtse, J.M.3    Howley, P.M.4
  • 302
    • 0026660417 scopus 로고
    • Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytes
    • Hubbert NL, Sedman SA and Schiller JT: Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytes. J Virol 66: 6237-6241, 1992.
    • (1992) J Virol , vol.66 , pp. 6237-6241
    • Hubbert, N.L.1    Sedman, S.A.2    Schiller, J.T.3
  • 303
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand J, Zambetti GP, Olson DC, George D and Levine AJ: The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69: 1237-1245, 1992.
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 304
    • 0030021031 scopus 로고    scopus 로고
    • WAF1/CIP1, gadd45, cyclins, cyclin-dependent kinases and PCNA in oral cancer
    • WAF1/CIP1, gadd45, cyclins, cyclin-dependent kinases and PCNA in oral cancer. Int J Oncol 8: 21-28, 1996.
    • (1996) Int J Oncol , vol.8 , pp. 21-28
    • Gujuluva, C.1    Sin, K.H.2    Park, N.-H.3
  • 305
    • 0027266971 scopus 로고
    • Human papillomavirus 16 EB expression disrupts the p53-mediated cellular response to DNA damage
    • Kessis TD, Slebos RJ, Nelson WG, et al: Human papillomavirus 16 EB expression disrupts the p53-mediated cellular response to DNA damage. Proc Natl Acad Sci USA 90: 3988-3992, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3988-3992
    • Kessis, T.D.1    Slebos, R.J.2    Nelson, W.G.3
  • 309
    • 0028168721 scopus 로고
    • Involvement of aberrant p53 expression and human papillomavirus in carcinoma of the head, neck and esophagus
    • Lewensohn-Fuchs I, Munck-Wikland E, Berke Z, et al: Involvement of aberrant p53 expression and human papillomavirus in carcinoma of the head, neck and esophagus. Anticancer Res 14: 1281-1286, 1994.
    • (1994) Anticancer Res , vol.14 , pp. 1281-1286
    • Lewensohn-Fuchs, I.1    Munck-Wikland, E.2    Berke, Z.3
  • 310
    • 0029883353 scopus 로고    scopus 로고
    • Human papilloma viruses and p53 mutations in normal premalignant and malignant oral epithelia
    • Mao E-J, Schwartz SM, Daling JR, Oda D, Tickman L and Beckmann AM: Human papilloma viruses and p53 mutations in normal premalignant and malignant oral epithelia. Int J Cancer 69: 152-158, 1996.
    • (1996) Int J Cancer , vol.69 , pp. 152-158
    • Mao, E.-J.1    Schwartz, S.M.2    Daling, J.R.3    Oda, D.4    Tickman, L.5    Beckmann, A.M.6
  • 311
    • 0029915967 scopus 로고    scopus 로고
    • Mutations in the p53 gene and human papillomavirus infection as significant prognostic factors in squamous cell carcinomas of the oral cavity
    • Chiba I, Shindoh M, Yasuda M, Yamazak Y, Amemiya A, Sao Y, Fujinaga K, Notani K-I and Fukuda H: Mutations in the p53 gene and human papillomavirus infection as significant prognostic factors in squamous cell carcinomas of the oral cavity. Oncogene 12: 1663-1668, 1996.
    • (1996) Oncogene , vol.12 , pp. 1663-1668
    • Chiba, I.1    Shindoh, M.2    Yasuda, M.3    Yamazak, Y.4    Amemiya, A.5    Sao, Y.6    Fujinaga, K.7    Notani, K.-I.8    Fukuda, H.9
  • 312
    • 0028069906 scopus 로고
    • Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus
    • Liu T-J, Zhang W-W, Taylor DL, Roth JA, Goepfert H and Clayman GL: Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus. Cancer Res 54: 3662-3667, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3662-3667
    • Liu, T.-J.1    Zhang, W.-W.2    Taylor, D.L.3    Roth, J.A.4    Goepfert, H.5    Clayman, G.L.6
  • 313
    • 0029879575 scopus 로고    scopus 로고
    • Transfection of wild-tpe TP53 induced differentiation in human gingival carcinoma cells
    • Takahashi R, Inagaki T, Matsuwari S, Fujioka M, et al: Transfection of wild-tpe TP53 induced differentiation in human gingival carcinoma cells. Eur J Cancer 32A: 533-539, 1996.
    • (1996) Eur J Cancer , vol.32 A , pp. 533-539
    • Takahashi, R.1    Inagaki, T.2    Matsuwari, S.3    Fujioka, M.4
  • 316
    • 0028326166 scopus 로고
    • Cancer screening based on genetic alterations in human tumors
    • Mao L and Sidransky D: Cancer screening based on genetic alterations in human tumors. Cancer Res 54 (Suppl): 1939s-1940s, 1994.
    • (1994) Cancer Res , vol.54 , Issue.SUPPL.
    • Mao, L.1    Sidransky, D.2
  • 318
    • 0030008882 scopus 로고    scopus 로고
    • Microsatellite instabilitity in preinvasive and invasive head and neck squamous carcinoma
    • El-Naggar AK, Hurr K, Huff V, Clayman GL, Luna MA and Batsakis JG: Microsatellite instabilitity in preinvasive and invasive head and neck squamous carcinoma. Am J Pathol 148: 2067-2072, 1996.
    • (1996) Am J Pathol , vol.148 , pp. 2067-2072
    • El-Naggar, A.K.1    Hurr, K.2    Huff, V.3    Clayman, G.L.4    Luna, M.A.5    Batsakis, J.G.6
  • 322
    • 0028920353 scopus 로고
    • Comparative genomic hybridization detects deletions and amplifications in head and neck squamous cell carcinomas
    • Speicher MR, Howe C, Crotty P, Du Manior S, Costa J and Ward DC: Comparative genomic hybridization detects deletions and amplifications in head and neck squamous cell carcinomas. Cancer Res 55: 1010-1013, 1995.
    • (1995) Cancer Res , vol.55 , pp. 1010-1013
    • Speicher, M.R.1    Howe, C.2    Crotty, P.3    Du Manior, S.4    Costa, J.5    Ward, D.C.6
  • 323
    • 0029449061 scopus 로고
    • Detection of DNA amplifications and deletions in oral squamous cell carcinoma cell lines by comparative genomic hybridization (CGH)
    • Matsumura K: Detection of DNA amplifications and deletions in oral
    • (1995) Kokubo Gakkai Zasshi , vol.62 , pp. 513-531
    • Matsumura, K.1
  • 324
    • 0028840534 scopus 로고
    • Distinct nonrandom patterns of chromosomal aberrations in the progression of squamous cell carcinomas of the head and neck
    • Soder AI, Hopman AHN, Ramaekers CS, Conradt C and Bosch FX: Distinct nonrandom patterns of chromosomal aberrations in the progression of squamous cell carcinomas of the head and neck. Cancer Res 55: 5030-5037, 1995.
    • (1995) Cancer Res , vol.55 , pp. 5030-5037
    • Soder, A.I.1    Hopman, A.H.N.2    Ramaekers, C.S.3    Conradt, C.4    Bosch, F.X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.