Cyclin D1/PRAD1 as a central target in oncogenesis

Journal of Laboratory and Clinical Medicine

Volumn 127, Issue 3, 1996, Pages 246-252

  Hosokawa, Yoshitaka ^b   Arnold, Andrew ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLINE; ONCOPROTEIN;

ADENOMA; ANIMAL; B CELL LYMPHOMA; CHROMOSOME 11; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; NEOPLASM; PARATHYROID TUMOR; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW;

ADENOMA; ANIMALS; CHROMOSOMES, HUMAN, PAIR 11; CYCLIN D1; CYCLINS; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; HUMANS; LYMPHOMA, B-CELL; NEOPLASMS; ONCOGENE PROTEINS; PARATHYROID NEOPLASMS;

EID: 0030091666     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2143(96)90092-X     Document Type: Review

References (67)

1. Hunter T, Pines J. Cyclins and cancer. Cell 1991;66:1071-4.
2. Motokura T, Arnold A. Cyclins and oncogenesis. Biochim Biophys Acta 1993;1155:63-78.
3. Sherr CJ. G1 phase progression: cycling on cue. Cell 1994; 79:551-5.
4. Hunter T, Pines J. Cyclins and cancer II: cyclin D and CDK inhibitors come of age. Cell 1994;79:573-82.
5. Sherr CJ, Roberts JM. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 1995;9:1149-63.
6. Lehner CF, O'Farrell PH. The roles of Drosophila cyclins A and B in mitotic control. Cell 1990;61:535-47.
7. Xiong Y, Connolly T, Fucher B, Beach D. Human D-type cyclin. Cell 1991;65:691-9.
8. Lew DJ, Dulic V, Reed SE. Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast. Cell 1991;66:1197-206.
9. Koff A, Cross F, Fisher A, et al. Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family. Cell 1991;66:1217-28.
10. Arnold A, Staunton CE, Kim HG, Gaz RD, Kronenberg HM. Monoclonality and abnormal parathyroid hormone genes in parathyroid adenomas. N Engl J Med 1988;318:658-62.
11. Arnold A, Kim HG, Gaz RD, et al. Molecular cloning and chromosome mapping of DNA rearranged with the parathyroid hormone gene in a parathyroid adenoma. J Clin Invest 1989;83:2034-40.
12. Rosenberg CL, Kim HG, Shows TB, Kronenberg HM, Arnold A. Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors. Oncogene 1991;6:449-53.
13. Motokura T, Bloom T, Kim HG, et al. A novel cyclin encoded by a bell-linked candidate oncogene. Nature 1991;350: 512-5.
14. Matsushime H, Roussel MF, Ashmun RA, Sherr CJ. Colonystimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell 1991;65;701-13.
15. Won K-A, Xiong Y, Beach D, Gilman MZ. Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts. Proc Natl Acad Sci USA 1992;89:9910-4.
16. Motokura T, Keyomarsi K, Kronenberg HM, Arnold A. Cloning and characterization of human cyclin D3, a cDNA closely related in sequence to the PRAD1/cyclin D1 protooncogene. J Biol Chem 1992;267:20412-5.
17. Musgrove EA, Hamilton JA, Lee CS, Sweeney KJE, Watts CKW, Sutherland RL. Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression. Mol Cell Biol 1993;13:3577-87.
18. Sewing A, Bürger C, Brüsselbach S, et al. Human cyclin D1 encodes a labile nuclear protein whose synthesis is directly induced by growth factors and suppressed by cyclic AMP. J Cell Sci 1993;104:545-54.
19. Hosokawa Y. Onga T, Nakashima K. Induction of D2 and D3 cyclin-encoding genes during promotion of the G1/S transition by prolactin in rat Nb2 cells. Gene 1994;147:249-52.
20. Arnold A. The cyclin D1/PRAD1 oncogene in human neoplasia. J Invest Med (in press).
21. Hsi E, Zukerberg LR, Yang WI, Arnold A. Cyclin D1 (PRAD1) expression in parathyroid adenomas: an immunohistochemical study [Abstract]. J Bone Miner Res 1995; 10(suppl 1):M526.
22. INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma. Science 1995;269:1281-4.
23. Khatib ZA, Matsushime H, Valentine M, Schapiro DN, Sherr CJ, Look AT. Coamplification of the CDK4 gene and MDM2 and GLI in human sarcomas. Cancer Res 1993;53: 5535-41.
24. He J, Allen JR, Collins VP, et al. CDK4 amplification is an alterative mechanism to p16 gene homozygous deletions in glioma cell lines. Cancer Res 1994;54:5804-7.
25. Korsmeyer SJ. Chromosomal translocation in lymphoid malignancies reveal novel proto-oncogenes. Annu Rev Immunol 1992;10:785-807.
26. Tsujimoto Y, Yunis J, Onorato-Showe L, Erickson J, Nowel PC, Croce CM. Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation. Science 1984;224: 1403-6.
27. Rosenberg CL, Wong E, Petty EM, et al. PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma. Proc Natl Acad Sci USA 1991;88:9638-42.
28. Withers DA, Harvey RC, Faust JB, Melnyk O, Carey K, Meeker TC. Characterization of a candidate bell gene. Mol Cell Biol 1991;11:4846-53.
29. Seto M, Yamamoto K, Iida S, et al. Gene rearrangement and overexpression of PRAD1 in lymphoid malignancy with t(11; 14)(q13;q32) translocation. Oncogene 1992;7:1401-6.
30. Komatsu H, Iida S, Yamamoto K, Mikuni C, et al. A variant chromosome translocation at 11q13 identifying PRAD1/cyclin D1 as the BCL-1 gene. Blood 1994;84:1226-31.
31. Williams ME, Swerdlow SH, Rosenberg CL, Arnold A. Chromosome 11 translocation breakpoints at the PRAD1/ cyclin D1 gene locus in centrocytic lymphoma. Leukemia 1993;7:241-5.
32. Bodrug SE, Warner BJ, Bath ML, Linderman GJ, Harris AW, Adams JM. Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene. EMBO J 1994;13:2124-30.
33. Lovec H, Grzeschiczek A, Kowalski M-B, Möröy T. Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice. EMBO J 1994:13:3487-95.
34. Yang W-I, Zukerberg LR, Motokura T, Arnold A, Harris NL. Cyclin D1 (bcl-1, PRAD1) protein expression in low grade B-cell lymphomas and reactive hyperplasis. Am J Pathol 1994;145:86-96.
35. Peters G, Fantl V, Smith R, Brookes S, Dickson C. Chromosome 11q13 markers and D-type cyclins in breast cancer. Breast Cancer Res Treat 1995;33:125-35.
36. Lammie GA, Fantl V, Smith R, et al. D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1. Oncogene 1991;6:439-44.
37. Peters G, Brookes S, Smith R, Dickson C. Tumorigenesis by mouse mammary tumor virus: evidence for a common region for provirus integration in mammary tumors. Cell 1983;33: 367-77.
38. Peters G. Inappropriate expression of growth factor genes in tumors induced by mouse mammary tumor virus. Semin Virol 1991;2:319-28.
39. Schuuring E, Verhoeven E, Mooi WJ, Michalides RJAM. Identification and cloning of two overexpressed genes, U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas. Oncogene 1992;7: 355-61.
40. Wang T, Cardiff R, Zukerberg L, Lees E, Arnold A, Schmidt E. Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature 1994;369:669-71.
41. Sicinski P, Donaher JL, Parker SB, et al. Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell 1995;82:621-30.
42. Buckley MF, Sweeney KJE, Hamilton JA, et al. Expression and amplification of cyclin genes in human breast cancer. Oncogene 1993;8:2127-33.
43. Zukerberg L, Yang W-I, Gadd M, et al. Cyclin D1 (PRAD1) protein expression in breast cancer: approximately one-third of infiltrating mammary carcinomas show overexpression of cyclin D1 oncogene. Modern Pathology 1995;8:560-7.
44. Gillett C, Fantl V, Smith R, et al. Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res 1994;54:1812-7.
45. Bartkova J, Lukas J, Müller H, Lützhft D, Straus M, Bartek J. Cyclin D1 protein expression and function in human breast cancer. Int J Cancer 1994;57:353-61.
46. Bartkova J, Lukas J, Strauss M, Bartek J. Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis. Oncogene 1995;10:775-8.
47. Hosokawa Y, Tu T, Tahara H, Smith AP, Arnold A. Absence of cyclin D1/PRAD1 point mutations in human breast cancers and parathyroid adenomas and identification of a new cyclin D1 gene polymorphism. Cancer Lett 1995;93:165-70.
48. Baldin V, Lukas J, Marcote MJ, Pagano M, Draetta G. Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev 1993;7:812-21.
49. Quelle E, Ashmun RA, Shurtleff SA, et al. Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. Genes Dev 1993;7:1559-71.
50. Pagano M, Theodoras AM, Tam SW, Draetta GF. Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts. Genes Dev 1994;8:1627-39.
51. Atadja P, Wong H, Veillete C, Riabowol K. Overexpression of cyclin D1 blocks proliferation of normal diploid fibroblasts. Exp Cell Res 1995;217:205-16.
52. Jiang W, Kahn SM, Zhou Y, et al. Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression. Oncogene 1993; 8:3447-57.
53. Lovec H, Sewing A, Lucibello F, Mueller R, Moroy T. Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: link between cell cycle control and malignant transformation. Oncogene 1994;9:323-6.
54. Hinds P, Dowdy S, Ng-Eaton E, Arnold A, Weinberg R. Function of a human cyclin as an oncogene. Proc Natl Acad Sci USA 1994;91:709-13.
55. Dowdy SF, Hind PW, Louie K, Reed SL Arnold A, Weinberg RA. Physical interaction of the retinoblastoma protein with human D cyclins. Cell 1993;73:499-511.
56. Ewen ME, Sluss HK, Sherr CJ, Matsushime H, Kato J-K, Livingston DM. Functional interaction of the retinoblastoma protein with mammalian D-type cyclin. Cell 1993;73: 487-97.
57. Lukas J, Bartkova J, Rohde M, Strauss M, Bartek J. Cyclin D1 is dispensable for Gl control in retinoblastoma gene-deficient cells independent of cdk4 activity. Mol Cell Biol 1995;15:2600-11.
58. Motokura T, Arnold A. PRAD1/cyclin D1 proto-oncogene: genomic organization, 5′ DNA sequence, and sequence of a tumor-specific rearrangement breakpoint. Gene Chromo Cancer 1993;7:89-95.
59. Philipp A, Schneider A, Väsrik I, et al. Repression of cyclin D1: a novel function of myc. Mol Cell Biol 1994;14:4032-43.
60. Müller H, Lukas J, Schneider A, et al. Cyclin D1 expression is regulated by the retinoblastoma protein. Proc Natl Acad Sci USA 1994;91:2945-9.
61. Lukas J, Müller H, Bartkova J, et al. DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in Gl. J Cell Biol 1994;125:625-38.
62. Herber B, Truss M, Müller R. Inducible regulatory elements in the human cyclin D1 promoter. Oncogene 1994;9:1295-304.
63. Betticher DC, Thatcher N, Altermatt HJ, Hoban P, Ryder WD, Heighway J. Alternate splicing produces a novel cyclin D1 transcript. Oncogene 1995;11:1005-11.
64. Rao SS, Chu C, Kohtz DS. Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulators. Mol Cell Biol 1994;14:5259-67.
65. Skapek SX, Rhee J, Spicer DB, Lassar AB. Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase. Science 1995;267:1022-4.
66. Freeman RS, Estus S, Johnson EM Jr. Analysis of cell cyclerelated gene expression in postmitotic neurons: selective induction of cyclin D1 during programmed cell death. Neuron 1994;12:343-55.
67. Tamaru T, Trigun SK, Okada M, Nakagawa H. Identification of cells expressing a D type G1 cyclin in matured brain: implication for its role in neuronal function. Neurosci Lett 1993;153:169-72.