Transfection of wild-type TP53 induces differentiation in human gingival carcinoma cells

European Journal of Cancer

Volumn 32, Issue 3, 1996, Pages 533-539

  Takahashi, R ^a   Inagaki, T ^a,b   Matsuwari, S ^c   Fujioka, M ^c   Maeda, S ^c   Ijuhin, N ^b   Haga, H ^a   Koh, T ^a   Shimada, K ^c   Saya, H ^d  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Gingival cancer; Squamous cell carcinoma; TP53 gene; Transfection

Indexed keywords

PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENICITY; CELL DIFFERENTIATION; CONTROLLED STUDY; GENETIC TRANSFECTION; GINGIVA TUMOR; HUMAN; HUMAN CELL; MOUSE; MOUTH CARCINOMA; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

ANIMALS; BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; CELL TRANSFORMATION, NEOPLASTIC; GENE TRANSFER TECHNIQUES; GENES, P53; GINGIVAL NEOPLASMS; HUMANS; MICE; MICE, NUDE; MOLECULAR SEQUENCE DATA; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0029879575     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/0959-8049(95)00611-7     Document Type: Article

References (30)

1. Levine AJ, Momand J, Finlay CA. The p53 tumour suppressor gene. Nature 1991, 351, 453-456.
2. Vogelstein B, Kinzler KW. P53 function and dysfunction (mini-review). Cell 1992, 21, 523-526.
3. Effect P, McCoy R, Abdel-Hamid M, Flynn K, Zhang Q, Busson P. Alterations of the p53 gene in nasopharyngeal carcinoma. J Virol 1992, 66, 3768-3775.
4. Sakai E, Tsuchida N. Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes. Oncogene 1992, 7, 927-933.
5. Maestro R, Dolcetti R, Gasparotto D, et al. High frequency of p54 alterations associated with protein overexpression in human squamous cell carcinoma of the larynx. Oncogene 1992, 7, 1159-1166.
6. Hollstein M, Sidransky D, Vogelstein B, Harris CC. p53 mutations in human cancers. Science 1991, 253, 49-53.
7. Baker SJ, Markowitz S, Fearon ER, Willson JK, Vogelstein B. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 1990, 249, 912-915.
8. Kyo E, Yokozaki H, Yanagihara K, et al. Reduced tumorigenicity and cell motility of gastric carcinoma cell line by introduction of wild-type p53 gene. Int J Oncol 1993, 3, 265-271.
9. Chen PL, Chen Y, Bookstein R, Lee WH. Genetic mechanisms of tumour suppression by the human p53 gene. Science 1990, 250, 1576-1580.
10. Radinsky R, Fidler IJ, Price JE, et al. Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild type p53. Oncogene 1994, 9, 1877-1883.
11. Brenner L, Munoz-Antonia T, Vellucci VF, Zhou ZL, Reiss M. Wild-type p53 tumor suppressor gene restores differentiation of human squamous carcinoma cells but not the response to transforming growth factor β1. Cell Growth Diff 1993, 4, 993-1004.
12. Inagaki T, Matsuwari S, Takahashi R, Shimada K, Fujie K, Maeda S. Establishment of human oral cancer cell lines (KOSC-2 and -3) carrying p53 and c-myc a by abnormalities Geneticin treatment. Int J Cancer 1994, 56, 301-308.
13. Chen C, Okayama H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 1987, 7, 2745-2752.
14. Deeley RG, Udell DS, Burns AT, Gordon JI, Goldberger RF. Kinetics of avian vitellogenin messenger RNA induction. Comparison between primary and secondary response to estrogen. J Biol Chem 1977, 252, 7913-7915.
15. Mattern J, Jaeger S, Wayss K, Volm M. Therapeutic response of human lung tumor xenografts to cyclophosphamide. Anticancer Res 1982, 2, 355-358.
16. Wijsman JH, Jonker RR, Keijzer R, et al. A new methods to detect apoptosis in paraffin sections: in situ end-labeling of fragmented DNA. J Histochem Cytochem 1993, 41, 7-12.
17. Gavlieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992, 119, 493-501.
18. Chen Y, Chen PL, Arnaiz N, Goodrich D, Lee WH. Expression of wild-type p53 in human A673 cells suppresses tumorigenicity but not growth rate. Oncogene 1991, 6, 1799-1805.
19. Merzak A, Raynal S, Rogers JP et al. Human wild type p53 inhibits cell proliferation and elicits dramatic morphological changes in human glioma cell lines in vitro. J Neurol Sci 1994, 127, 125-133.
20. Ehinger M, Nilsson E, Persson AM, Olsson I, Gullberg U. Involvement of the tumor suppressor gene p53 in tumor necrosis factor-induced differentiation of the leukemic cell line K562. Cell Growth Differ 1995, 6, 9-17.
21. Woodworth CD, Wang H, Simpson S, Alvarez Salas LM, Notario V. Overexpression of wild-type p53 alters growth and differentiation of normal human keratinocytes but not of human papillomavirus-expressing cell lines. Cell Growth Differ 1993, 4, 367-376.
22. Nervi C, Vollberg TM, George MD, Zelent A. Expression of nuclear retinoic acid receptors in normal tracheobronchial cells and in lung carcinoma cells. Exp Cell Res 1991, 195, 163-170.
23. Poddar S, Hong WK, Thacher SM, Lotan R. Retinoic acid suppression of squamous differentiation in human head-and-neck squamous carcinoma cells. Int J Cancer 1991, 48, 239-247.
24. Sugiyama M, Speight PM, Prime SS, Watt FM. Comparison of integrin expression and terminal differentiation capacity in cell lines derived from oral squamous cell carcinomas. Carcinogenesis 1993, 14, 2171-2176.
25. Rorcke EA, Eckert RL. Stable expression of transfected human involucrin gene in various cell types: evidence for in situ cross-linking by type I and type II transglutaminase. J Invest Dermatol 1991, 97, 543-548.
26. Zhang W, Shay WS, Deisseroth A. Inactive p53 mutants may enhance the transcriptional activity of wild-type p53. Cancer Res 1993, 53, 4772-4775.
27. Bischoff JR, Casso D, Beach D. Human p53 inhibits growth in Schizosaccharomyces pombe. Mol Cell Biol 1992, 12, 1405-1411.
28. Halevy O, Michalovitz D, Oren M. Different tumor-derived p53 mutations exhibit distinct biological activities. Science 1990, 250, 113-116.
29. Moberg KH, Tyndall WA, Hall DJ. Wild-type murine p53 represses transcription from the murine c-myc promoter in a human glial cell line. J Cell Biochem 1992, 49, 208-215.
30. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M. Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin 6. Nature 1991, 352, 345-347.