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Volumn 8, Issue 1, 1997, Pages 61-70

Multidrug resistance in Mycobacterium tuberculosis

Author keywords

ethambutol; fluoroquinolones; isoniazid; pyrazinamide; rifampicin; short course chemotherapy; streptomycin; tuberculosis

Indexed keywords

CAPREOMYCIN; CYCLOSERINE; ETHAMBUTOL; ETHIONAMIDE; ISONIAZID; KANAMYCIN; OFLOXACIN; PYRAZINAMIDE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; SPARFLOXACIN; STREPTOMYCIN; TUBERCULOSTATIC AGENT;

EID: 0030994680     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(96)00356-1     Document Type: Article
Times cited : (29)

References (123)
  • 1
    • 0028887541 scopus 로고
    • Bacterial resistance mechanisms to β-lactam antibiotics: Assessment of management strategies
    • Dudley M. Bacterial resistance mechanisms to β-lactam antibiotics: assessment of management strategies. Pharmacotherapy 1995:S9-S14.
    • (1995) Pharmacotherapy
    • Dudley, M.1
  • 2
    • 0028950023 scopus 로고
    • Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR
    • Dutka-Malen S, Evers S, Courvalin P. Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR. J Clin Microbiol 1995;33:24-27.
    • (1995) J Clin Microbiol , vol.33 , pp. 24-27
    • Dutka-Malen, S.1    Evers, S.2    Courvalin, P.3
  • 3
    • 0030003732 scopus 로고    scopus 로고
    • Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: Results of a 30-center national surveillance study
    • Doern GV, Brueggemann A, Holley HP, Rauch AM. Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: results of a 30-center national surveillance study. Antimicrob Agents Chemother 1996;40:1208-1213.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1208-1213
    • Doern, G.V.1    Brueggemann, A.2    Holley, H.P.3    Rauch, A.M.4
  • 4
    • 0026760182 scopus 로고
    • The crisis in antibiotic resistance
    • Neu HC. The crisis in antibiotic resistance. Science 1992;257:1064-1072.
    • (1992) Science , vol.257 , pp. 1064-1072
    • Neu, H.C.1
  • 7
    • 0028220996 scopus 로고
    • Evolution of drug-resistant tuberculosis: A tale of two species
    • Iseman MD. Evolution of drug-resistant tuberculosis: a tale of two species. Proc Natl Acad Sci USA 1994;91:2428-2429.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2428-2429
    • Iseman, M.D.1
  • 8
    • 0028127262 scopus 로고
    • Tuberculosis susceptibility patterns, predictors of multidrug resistance, and implications for initial therapeutic regimens at a New York hospital
    • Weltman AC, Rose DN. Tuberculosis susceptibility patterns, predictors of multidrug resistance, and implications for initial therapeutic regimens at a New York hospital. Arch Intern Med 1994;154:2161-2167.
    • (1994) Arch Intern Med , vol.154 , pp. 2161-2167
    • Weltman, A.C.1    Rose, D.N.2
  • 9
    • 0026552319 scopus 로고
    • Epidemiology of mycobacterial diseases in AIDS
    • Horsburgh Jr. CR. Epidemiology of mycobacterial diseases in AIDS. Res Microbiol 1992;143:372-377.
    • (1992) Res Microbiol , vol.143 , pp. 372-377
    • Horsburgh C.R., Jr.1
  • 10
    • 0028902930 scopus 로고
    • The epidemiology of tuberculosis among foreign-born persons in the United States 1986-1993
    • McKenna MT, McCray E, Onorato I. The epidemiology of tuberculosis among foreign-born persons in the United States 1986-1993. N Engl J Med 1995;332:1071-1076.
    • (1995) N Engl J Med , vol.332 , pp. 1071-1076
    • McKenna, M.T.1    McCray, E.2    Onorato, I.3
  • 12
    • 0025767090 scopus 로고
    • Permeability of mycobacterial cell wall
    • Nikaido H, Jarlier V. Permeability of mycobacterial cell wall. Res Microbiol 1991;142:437-443.
    • (1991) Res Microbiol , vol.142 , pp. 437-443
    • Nikaido, H.1    Jarlier, V.2
  • 13
    • 0007630831 scopus 로고
    • Über Hydrazinderivate der Pyridincarbonsäuren
    • Meyer H, Mally J. Über Hydrazinderivate der Pyridincarbonsäuren. Monatshefte für Chemie 1912;33:393-414.
    • (1912) Monatshefte für Chemie , vol.33 , pp. 393-414
    • Meyer, H.1    Mally, J.2
  • 14
    • 0001548959 scopus 로고
    • Synthetic tuberculostatics show promise
    • Fox HH. Synthetic Tuberculostatics show promise. Chem Eng News 1951;29:3963-3964.
    • (1951) Chem Eng News , vol.29 , pp. 3963-3964
    • Fox, H.H.1
  • 16
    • 0342937461 scopus 로고
    • Antituberculous properties of hydrazines of isonicotinic acid (Rimifon, Marsalid)
    • Steenken Jr. W, Wolinsky E. Antituberculous properties of hydrazines of isonicotinic acid (Rimifon, Marsalid). Am Rev Tuberc 1952;65:365-375.
    • (1952) Am Rev Tuberc , vol.65 , pp. 365-375
    • Steenken W., Jr.1    Wolinsky, E.2
  • 17
    • 75549111449 scopus 로고
    • Isotopic studies on the effect of isoniazid on protein synthesis of mycobacteria
    • Tsukamura M, Tsukamura S. Isotopic studies on the effect of isoniazid on protein synthesis of mycobacteria. Jpn J Tuberc 1963;11:14-17.
    • (1963) Jpn J Tuberc , vol.11 , pp. 14-17
    • Tsukamura, M.1    Tsukamura, S.2
  • 18
    • 0014516373 scopus 로고
    • A review of the action of isoniazid
    • Youatt J. A review of the action of isoniazid. Am Rev Respir Dis 1969;99:729-749.
    • (1969) Am Rev Respir Dis , vol.99 , pp. 729-749
    • Youatt, J.1
  • 21
    • 0001293738 scopus 로고
    • Sterilization of tubercle bacilli by isonicotinic acid hydrazide and the incidence of variants resistant to the drug in vitro
    • Middlebrook G. Sterilization of tubercle bacilli by isonicotinic acid hydrazide and the incidence of variants resistant to the drug in vitro. Am Rev Tuberc 1952;65:765-767.
    • (1952) Am Rev Tuberc , vol.65 , pp. 765-767
    • Middlebrook, G.1
  • 22
    • 0001496477 scopus 로고
    • Some observations on the pathogenicity of isoniazid-resistant variants of tubercle bacilli
    • Middlebrook G, Cohn ML. Some observations on the pathogenicity of isoniazid-resistant variants of tubercle bacilli. Science 1953;118:297-299.
    • (1953) Science , vol.118 , pp. 297-299
    • Middlebrook, G.1    Cohn, M.L.2
  • 23
    • 0026705772 scopus 로고
    • The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis
    • Zhang Y, Heym B, Allen B, Young D, Cole S. The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis. Nature 1992;358:591-3.
    • (1992) Nature , vol.358 , pp. 591-593
    • Zhang, Y.1    Heym, B.2    Allen, B.3    Young, D.4    Cole, S.5
  • 24
    • 0027248433 scopus 로고
    • Characterization of the katG gene encoding a catalase-peroxidase required for the isoniazid susceptibility of Mycobacterium tuberculosis
    • Heym B, Zhang Y, Poulet S, Young D, Cole ST. Characterization of the katG gene encoding a catalase-peroxidase required for the isoniazid susceptibility of Mycobacterium tuberculosis. J Bacteriol 1993;175:4255-4259.
    • (1993) J Bacteriol , vol.175 , pp. 4255-4259
    • Heym, B.1    Zhang, Y.2    Poulet, S.3    Young, D.4    Cole, S.T.5
  • 25
    • 0027162576 scopus 로고
    • Genetic basis of isoniazid resistance of Mycobacterium tuberculosis
    • Zhang Y. Genetic basis of isoniazid resistance of Mycobacterium tuberculosis. Res Microbiol 1993;144:143-149.
    • (1993) Res Microbiol , vol.144 , pp. 143-149
    • Zhang, Y.1
  • 26
    • 0022366614 scopus 로고
    • Catalases HPI and HPII in Escherichia coli are induced independently
    • Loewen PC, Switala J, Triggs-Raine BL. Catalases HPI and HPII in Escherichia coli are induced independently. Arch Biochem Biophys 1985;243:144-149.
    • (1985) Arch Biochem Biophys , vol.243 , pp. 144-149
    • Loewen, P.C.1    Switala, J.2    Triggs-Raine, B.L.3
  • 28
    • 0018367454 scopus 로고
    • Purification of the o-Dianisidine peroxidase from Escherichia coli B
    • Claiborne A, Fridovich I. Purification of the o-Dianisidine Peroxidase from Escherichia coli B. J Biol Chem 1979;254:4245-4252.
    • (1979) J Biol Chem , vol.254 , pp. 4245-4252
    • Claiborne, A.1    Fridovich, I.2
  • 29
    • 0027162576 scopus 로고
    • Genetic basis of isoniazid resistance of Mycobacterium tuberculosis
    • Zhang Y. Genetic basis of isoniazid resistance of Mycobacterium tuberculosis. Res Microbiol 1993;144:143-9.
    • (1993) Res Microbiol , vol.144 , pp. 143-149
    • Zhang, Y.1
  • 30
    • 0027993499 scopus 로고
    • Mechanistic studies of the oxidation of isoniazid by the catalase-peroxidase from Mycobacterium tuberculosis
    • Johnsson K, Schultz PG. Mechanistic studies of the oxidation of isoniazid by the catalase-peroxidase from Mycobacterium tuberculosis. J Am Chem Soc 1994;116:7425-7426.
    • (1994) J Am Chem Soc , vol.116 , pp. 7425-7426
    • Johnsson, K.1    Schultz, P.G.2
  • 31
    • 0029042636 scopus 로고
    • Studies on the mechanism of action of isoniazid and ethionamide in the chemotherapy of tuberculosis
    • Johnsson K, King D, Schultz PG. Studies on the mechanism of action of isoniazid and ethionamide in the chemotherapy of tuberculosis. J Am Chem Soc 1995;117:5009-5010.
    • (1995) J Am Chem Soc , vol.117 , pp. 5009-5010
    • Johnsson, K.1    King, D.2    Schultz, P.G.3
  • 32
    • 0028960179 scopus 로고
    • Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis
    • Heym B, Alzari P, Honoré N, Cole S. Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis. Mol Microbiol 1995;15:235-245.
    • (1995) Mol Microbiol , vol.15 , pp. 235-245
    • Heym, B.1    Alzari, P.2    Honoré, N.3    Cole, S.4
  • 33
    • 0028886398 scopus 로고
    • Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis
    • Rouse DA, Li Z, Bai G-H, Morris SL. Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis. Antimicrob Agents Chemother 1995;39:2472-2477.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2472-2477
    • Rouse, D.A.1    Li, Z.2    Bai, G.-H.3    Morris, S.L.4
  • 34
    • 0030042509 scopus 로고    scopus 로고
    • Characterization of the catalase-peroxidase gene katG and inhA locus in isoniazid-resistant and -susceptible strains of Mycobacterium tuberculosis by automated DNA sequencing: Restricted array of mutations associated with drug resistance
    • Musser JM, Kapur V, Williams DL, Kreiswirth BN, van Soolingen D, van Embden JDA. Characterization of the catalase-peroxidase gene katG) and inhA locus in isoniazid-resistant and -susceptible strains of Mycobacterium tuberculosis by automated DNA sequencing: restricted array of mutations associated with drug resistance. J Infect Dis 1996;173:196-202.
    • (1996) J Infect Dis , vol.173 , pp. 196-202
    • Musser, J.M.1    Kapur, V.2    Williams, D.L.3    Kreiswirth, B.N.4    Van Soolingen, D.5    Van Embden, J.D.A.6
  • 35
    • 0025995263 scopus 로고
    • Bacterial catalase-peroxidases are gene duplicated members of the plant peroxidase superfamily
    • Welinder KG. Bacterial catalase-peroxidases are gene duplicated members of the plant peroxidase superfamily. Biochem Biophys Acta 1991;1080:215-220.
    • (1991) Biochem Biophys Acta , vol.1080 , pp. 215-220
    • Welinder, K.G.1
  • 36
    • 0026465558 scopus 로고
    • The catalase-peroxidase of Mycobacterium intracellulare: Nucleotide sequence analysis and expression in Escherichia coli
    • Morris SL, Nair J, Rouse DA. The catalase-peroxidase of Mycobacterium intracellulare: nucleotide sequence analysis and expression in Escherichia coli. J Gen Microbiol 1992;138:2363-2370.
    • (1992) J Gen Microbiol , vol.138 , pp. 2363-2370
    • Morris, S.L.1    Nair, J.2    Rouse, D.A.3
  • 37
    • 0014285414 scopus 로고
    • Acquired isoniazid resistance and catalase activity
    • Wayne LG, Diaz GA, Doubek JR. Acquired isoniazid resistance and catalase activity. Am Rev Respir Dis 1968;97:909-913.
    • (1968) Am Rev Respir Dis , vol.97 , pp. 909-913
    • Wayne, L.G.1    Diaz, G.A.2    Doubek, J.R.3
  • 38
    • 0028156861 scopus 로고
    • InhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis
    • Banerjee A, Dubnau E, Quemard A, Balasubramanian V, Um KS, Wilson T, et al. inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis. Science 1994;263:227-230.
    • (1994) Science , vol.263 , pp. 227-230
    • Banerjee, A.1    Dubnau, E.2    Quemard, A.3    Balasubramanian, V.4    Um, K.S.5    Wilson, T.6
  • 39
    • 0007949255 scopus 로고
    • L' Activité antituberculeuse de l' Ethionamide
    • Rist N. L' Activité antituberculeuse de l' Ethionamide. Adv Tuberc Res 1960;10:69-126.
    • (1960) Adv Tuberc Res , vol.10 , pp. 69-126
    • Rist, N.1
  • 40
    • 0028988237 scopus 로고
    • Crystal stucture and function of the isoniazid target of Mycobacterium tuberculosis
    • Dessen A, Quémard A, Blunchard JS, Jacobs Jr. WR, Sacchettini JC. Crystal stucture and function of the isoniazid target of Mycobacterium tuberculosis. Science 19995;267:1638-1641.
    • (1995) Science , vol.267 , pp. 1638-1641
    • Dessen, A.1    Quémard, A.2    Blunchard, J.S.3    Jacobs W.R., Jr.4    Sacchettini, J.C.5
  • 41
    • 0028817097 scopus 로고
    • Rapid Mycobacterium species assignment and unambiguous identification of mutations associated with antimicrobial resistance in Mycobacterium tuberculosis by automated DNA sequencing
    • Kapur V, Li L-L, Hamrick MR, Plikaytis BB, Shinnick TM, Telenti A, et al. Rapid Mycobacterium species assignment and unambiguous identification of mutations associated with antimicrobial resistance in Mycobacterium tuberculosis by automated DNA sequencing. Arch Pathol Lab Med 1995;119:131-8.
    • (1995) Arch Pathol Lab Med , vol.119 , pp. 131-138
    • Kapur, V.1    Li, L.-L.2    Hamrick, M.R.3    Plikaytis, B.B.4    Shinnick, T.M.5    Telenti, A.6
  • 42
    • 0029121093 scopus 로고
    • New isoniazid ethionamide resistance gene mutation and screening for multidrug-resistant Mycobacterium tuberculosis strains
    • Ristow M, Möhlig M, Rifai M, Schatz H, Feldmann K, Pfeiffer A. New isoniazid ethionamide resistance gene mutation and screening for multidrug-resistant Mycobacterium tuberculosis strains. Lancet 1995;346:502-503.
    • (1995) Lancet , vol.346 , pp. 502-503
    • Ristow, M.1    Möhlig, M.2    Rifai, M.3    Schatz, H.4    Feldmann, K.5    Pfeiffer, A.6
  • 43
    • 0014548884 scopus 로고
    • An enzyme system of Mycobacterium tuberculosis that reacts specifically with Isoniazid. II
    • Youatt J, Tham SH. An Enzyme System of Mycobacterium tuberculosis that reacts specifically with Isoniazid. II. Am Rev Respir Dis 1969;100:31-37.
    • (1969) Am Rev Respir Dis , vol.100 , pp. 31-37
    • Youatt, J.1    Tham, S.H.2
  • 44
    • 0030032612 scopus 로고    scopus 로고
    • Flavin-dependent alkyl hydroperoxide reductase from Salmonella typhimurium. 1. Purification and enzymatic activities of overexpressed AhpF and AhpC proteins
    • Poole LB, Ellis HR. Flavin-dependent alkyl hydroperoxide reductase from Salmonella typhimurium. 1. Purification and Enzymatic activities of overexpressed AhpF and AhpC Proteins. Biochemistry 1996;35:56-64.
    • (1996) Biochemistry , vol.35 , pp. 56-64
    • Poole, L.B.1    Ellis, H.R.2
  • 45
    • 0024785396 scopus 로고
    • Identification and molecular analysis of OxyR-regulates promoters important for the bacterial adaptation to oxidative stress
    • Tartaglia LA, Storz G, Ames BN. Identification and molecular analysis of OxyR-regulates promoters important for the bacterial adaptation to oxidative stress. J Mol Biol 1989;210:709-719.
    • (1989) J Mol Biol , vol.210 , pp. 709-719
    • Tartaglia, L.A.1    Storz, G.2    Ames, B.N.3
  • 46
    • 0028882958 scopus 로고
    • Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene:Implications for sensitivity to isoniazid
    • Deretic V, Philipp W, Dhandayutapani S, Mudd MH, Curcic R, Garbe T, et al. Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene:implications for sensitivity to isoniazid. Mol Microbiol 1995;17:889-900.
    • (1995) Mol Microbiol , vol.17 , pp. 889-900
    • Deretic, V.1    Philipp, W.2    Dhandayutapani, S.3    Mudd, M.H.4    Curcic, R.5    Garbe, T.6
  • 48
    • 0029888258 scopus 로고    scopus 로고
    • Oxidative stress reponse and its role in sensitivity to isoniazid in Mycobacteria: Characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis
    • Dhandayuthapani S, Zhang Y, Mudd MH, Deretic V. Oxidative stress reponse and its role in sensitivity to isoniazid in Mycobacteria: characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis. J Bacteriol 1996;187:3641-3649.
    • (1996) J Bacteriol , vol.187 , pp. 3641-3649
    • Dhandayuthapani, S.1    Zhang, Y.2    Mudd, M.H.3    Deretic, V.4
  • 49
    • 0029996734 scopus 로고    scopus 로고
    • Compensatory ahpC gene expression in isoniazid-resistant Mycobacterium tuberculosis
    • Sherman DR, Mdluli K, Hickey MJ, Arain TM, Morris SL, Barry III CE, et al. Compensatory ahpC Gene expression in isoniazid-resistant Mycobacterium tuberculosis. Science 1996;272:1643-1643.
    • (1996) Science , vol.272 , pp. 1643-1643
    • Sherman, D.R.1    Mdluli, K.2    Hickey, M.J.3    Arain, T.M.4    Morris, S.L.5    Barry C.E. III6
  • 50
    • 0029915633 scopus 로고    scopus 로고
    • AhpC, a gene involved in isoniazid resistance of the Mycobacterium tuberculosis complex
    • Wilson TM, Collins DM. ahpC, a gene involved in isoniazid resistance of the Mycobacterium tuberculosis complex. Mol Microbiol 1996;19:1025-1034.
    • (1996) Mol Microbiol , vol.19 , pp. 1025-1034
    • Wilson, T.M.1    Collins, D.M.2
  • 51
    • 0024637416 scopus 로고
    • Present status of chemotherapy for tuberculosis
    • Grosset JH. Present status of chemotherapy for tuberculosis. Rev Infect Dis 1989;11:5347-5352.
    • (1989) Rev Infect Dis , vol.11 , pp. 5347-5352
    • Grosset, J.H.1
  • 54
    • 0020791848 scopus 로고
    • Rifampin: Mechanisms of action and resistance
    • Wehrli W. Rifampin: mechanisms of action and resistance. Rev Infect Dis 1983;5:S407-S411.
    • (1983) Rev Infect Dis , vol.5
    • Wehrli, W.1
  • 55
    • 0027483138 scopus 로고
    • The molecular basis of rifampin resistance in Mycobacterium leprae
    • Honoré N, Cole ST. The molecular basis of rifampin resistance in Mycobacterium leprae. Antimicrob Agents Chemother 1993;37:414-418.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 414-418
    • Honoré, N.1    Cole, S.T.2
  • 57
    • 0342937457 scopus 로고
    • Detection of rifampin resistance mutations in Mycobacterium tuberculosis and M. leprae
    • Persing DH, Smith TF, Tenover FC, White TJ (eds). American Society for Microbiology, Washington D.C.
    • Imboden P, Cole S, Bodmer T, Telenti A. Detection of rifampin resistance mutations in Mycobacterium tuberculosis and M. leprae. In: Persing DH, Smith TF, Tenover FC, White TJ (eds) Diagnostic Molecular Microbiology. Principles and Applications. American Society for Microbiology, Washington D.C., 1993;519-526.
    • (1993) Diagnostic Molecular Microbiology. Principles and Applications , pp. 519-526
    • Imboden, P.1    Cole, S.2    Bodmer, T.3    Telenti, A.4
  • 58
    • 0027538104 scopus 로고
    • Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis
    • Telenti A, Imboden P, Marchesi F, Lowrie D, Cole ST, Colston MJ, et al. Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis. Lancet 1993;341:647-650.
    • (1993) Lancet , vol.341 , pp. 647-650
    • Telenti, A.1    Imboden, P.2    Marchesi, F.3    Lowrie, D.4    Cole, S.T.5    Colston, M.J.6
  • 59
    • 0024319151 scopus 로고
    • Characterization of the pleiotropic phenotypes of rifampin-resistant rpoB mutants of Escherichia coli
    • Jin DJ, Gross CA. Characterization of the pleiotropic phenotypes of rifampin-resistant rpoB mutants of Escherichia coli. J Bacteriol 1989;171:5229-5231.
    • (1989) J Bacteriol , vol.171 , pp. 5229-5231
    • Jin, D.J.1    Gross, C.A.2
  • 60
    • 0028863891 scopus 로고
    • Rapid detection of rifampicin resistance in sputum and biopsy specimens from tuberculosis patients by PCR and line probe assay
    • Beenhouwer De H, Lhiang Z, Jannes G, Mijs W, Machtelinckx L, Rossau R, et al. Rapid detection of rifampicin resistance in sputum and biopsy specimens from tuberculosis patients by PCR and line probe assay. Tuberc Lung Dis 1995;76:425-30.
    • (1995) Tuberc Lung Dis , vol.76 , pp. 425-430
    • De Beenhouwer, H.1    Lhiang, Z.2    Jannes, G.3    Mijs, W.4    Machtelinckx, L.5    Rossau, R.6
  • 61
    • 0027495006 scopus 로고
    • Direct, automated detection of rifampicin-resistant Mycobacterium tuberculosis by polymerase chain reaction and single-strand conformation polymorphism analysis
    • Telenti A, Imboden P, Marchesi F, Schmidheini T, Bodmer T. Direct, automated detection of rifampicin-resistant Mycobacterium tuberculosis by polymerase chain reaction and single-strand conformation polymorphism analysis. Antimicrob Agents Chemother 1993;37:2054-2058.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 2054-2058
    • Telenti, A.1    Imboden, P.2    Marchesi, F.3    Schmidheini, T.4    Bodmer, T.5
  • 62
    • 0015914856 scopus 로고
    • Cyclic blockade of initiation sites by streptomycin-damaged ribosomes in Escherichia coli:An explanation for dominance of sensitivity
    • Wallace BJ, Davis BD. Cyclic Blockade of initiation sites by streptomycin-damaged ribosomes in Escherichia coli:an explanation for dominance of sensitivity. J Mol Biol 1973;75:377-390.
    • (1973) J Mol Biol , vol.75 , pp. 377-390
    • Wallace, B.J.1    Davis, B.D.2
  • 63
    • 0015527272 scopus 로고
    • Location of amino acid replacements in protein S12 isolated from Escherichia coli mutants resistant to streptomycin
    • Funatsu G, Wittmann HG. Location of amino acid replacements in protein S12 isolated from Escherichia coli mutants resistant to streptomycin. J Mol Biol 1975;68:547-550.
    • (1975) J Mol Biol , vol.68 , pp. 547-550
    • Funatsu, G.1    Wittmann, H.G.2
  • 64
    • 0014385399 scopus 로고
    • Antibiotic inhibitors of the bacterial ribosome
    • Weisblum B, Davies J. Antibiotic inhibitors of the bacterial ribosome. Bacteriol Rev 1968;32:493-528.
    • (1968) Bacteriol Rev , vol.32 , pp. 493-528
    • Weisblum, B.1    Davies, J.2
  • 65
    • 0016264804 scopus 로고
    • The effects of streptomycin or dihydrostrepotmycin binding to 16S RNA or to 30S ribosomal subunits
    • Garvin RT, Biswas DK, Gorini L. The Effects of streptomycin or dihydrostrepotmycin binding to 16S RNA or to 30S ribosomal subunits. Proc Nat Acad Sci USA 1974;71:3814-3818.
    • (1974) Proc Nat Acad Sci USA , vol.71 , pp. 3814-3818
    • Garvin, R.T.1    Biswas, D.K.2    Gorini, L.3
  • 66
    • 0023238983 scopus 로고
    • Interaction of antibiotics with functional sites in 16S ribosomal RNA
    • Moazed D, Noller HF. Interaction of antibiotics with functional sites in 16S ribosomal RNA. Nature 1987;327:389-394.
    • (1987) Nature , vol.327 , pp. 389-394
    • Moazed, D.1    Noller, H.F.2
  • 67
    • 0008234804 scopus 로고
    • Problems of drug resistance
    • Mitchison DA. Problems of drug resistance. Br Med Bull 1954;10:115-124.
    • (1954) Br Med Bull , vol.10 , pp. 115-124
    • Mitchison, D.A.1
  • 68
  • 69
    • 0028082028 scopus 로고
    • Genetic alterations in streptomycin-resistant Mycobacterium tuberculosis: Mapping of mutations conferring resistance
    • Meier A, Kirschner P, Bange F-C, Vogel U, Böttger EC. Genetic alterations in streptomycin-resistant Mycobacterium tuberculosis: mapping of mutations conferring resistance. Antimicrob Agents Chemother 1994;38:228-233.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 228-233
    • Meier, A.1    Kirschner, P.2    Bange, F.-C.3    Vogel, U.4    Böttger, E.C.5
  • 70
    • 0029912436 scopus 로고    scopus 로고
    • Characterization of streptomycin resistance mechanisms among Mycobacterium tuberculosis isolates from patients in New York City
    • Cooksey RC, Morlock GP, McQueen A, Glickman SE, Crawford JT. Characterization of streptomycin resistance mechanisms among Mycobacterium tuberculosis isolates from patients in New York City. Antimicrob Agents Chemother 1996;40:1186-1188.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1186-1188
    • Cooksey, R.C.1    Morlock, G.P.2    McQueen, A.3    Glickman, S.E.4    Crawford, J.T.5
  • 71
    • 0026670271 scopus 로고
    • The nucleotide sequence of the promoter, 16s rRNA and spacer region of the ribosomal RNA operon of Mycobacterium tuberculosis and comparison with Mycobacterium leprae precursor rRNA
    • Kempsell KE, Ji Y-E, Estrada ICE, Colston MJ, Cox RA. The nucleotide sequence of the promoter, 16S rRNA and spacer region of the ribosomal RNA operon of Mycobacterium tuberculosis and comparison with Mycobacterium leprae precursor rRNA. J Gen Microbiol 1992;138:1717-1727.
    • (1992) J Gen Microbiol , vol.138 , pp. 1717-1727
    • Kempsell, K.E.1    Ji, Y.-E.2    Estrada, I.C.E.3    Colston, M.J.4    Cox, R.A.5
  • 72
    • 0028100019 scopus 로고
    • Resistance to drugs targeting protein synthesis in mycobacteria
    • Böttger E. Resistance to drugs targeting protein synthesis in mycobacteria. Trends Microbiol 1994;2:416-421.
    • (1994) Trends Microbiol , vol.2 , pp. 416-421
    • Böttger, E.1
  • 74
    • 0027489149 scopus 로고
    • Molecular basis of streptomycin resistance in Mycobacterium tuberculosis: Alterations of the ribosomal protein S12 gene and point mutations within a functional 16S ribosomal RNA pseudoknot
    • Finken M, Kirschner P, Meier A, Wrede A. Böttger EC. Molecular basis of streptomycin resistance in Mycobacterium tuberculosis: alterations of the ribosomal protein S12 gene and point mutations within a functional 16S ribosomal RNA Pseudoknot. Mol Microbiol 1993;9:1239-1246.
    • (1993) Mol Microbiol , vol.9 , pp. 1239-1246
    • Finken, M.1    Kirschner, P.2    Meier, A.3    Wrede, A.4    Böttger, E.C.5
  • 75
    • 0028942364 scopus 로고
    • Novel mutation in the 16S rRNA associated with streptomycin dependence in Mycobacterium tuberculosis
    • Honoré N, Marchal G, Cole ST. Novel mutation in the 16S rRNA associated with streptomycin dependence in Mycobacterium tuberculosis. Antimicrob Agents Chemother 1995;39:769-770.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 769-770
    • Honoré, N.1    Marchal, G.2    Cole, S.T.3
  • 76
    • 0025737972 scopus 로고
    • A functional pseudoknot in 16S ribosomal RNA
    • Powers T, Noller HF. A functional pseudoknot in 16S ribosomal RNA. EMBO J 1991;10:2203-2214.
    • (1991) EMBO J , vol.10 , pp. 2203-2214
    • Powers, T.1    Noller, H.F.2
  • 77
    • 0015694583 scopus 로고
    • Mechanisms of antibiotic resistance in bacteria
    • Benveniste R, Davies J. Mechanisms of antibiotic resistance in bacteria. Annu Rev Biochem 1973;42:471-506.
    • (1973) Annu Rev Biochem , vol.42 , pp. 471-506
    • Benveniste, R.1    Davies, J.2
  • 78
    • 0018774431 scopus 로고
    • Isolation of plasmids from mycobacteria
    • Crawford JT, Bates JH. Isolation of plasmids from mycobacteria. Infect Immunol 1979;24:979-981.
    • (1979) Infect Immunol , vol.24 , pp. 979-981
    • Crawford, J.T.1    Bates, J.H.2
  • 79
    • 0342663538 scopus 로고
    • Plasmids, antibiotic resistance, and mobile genetic elements in mycobacteria
    • McFadden J (ed). Surrey University Press, London
    • Martin C, Ranes M, Gicquel B. Plasmids, Antibiotic resistance, and mobile genetic elements in mycobacteria. In: McFadden J (ed) The Molecular Biology of the Mycobacteria. Surrey University Press, London. 1990:120-138.
    • (1990) The Molecular Biology of the Mycobacteria , pp. 120-138
    • Martin, C.1    Ranes, M.2    Gicquel, B.3
  • 80
    • 0017123289 scopus 로고
    • Inhibition of dihydrostreptomycin binding to Mycobacterium smegmatis by monovalent and divalent cation salts
    • Beggs WH, Andrews FA. Inhibition of dihydrostreptomycin binding to Mycobacterium smegmatis by monovalent and divalent cation salts. Antimicrob Agents Chemother 1976;9:393-396.
    • (1976) Antimicrob Agents Chemother , vol.9 , pp. 393-396
    • Beggs, W.H.1    Andrews, F.A.2
  • 81
    • 0017644533 scopus 로고
    • Effects of membrane-energy mutations and cations on streptomycin and gentamicin accumulation by bacteria: A model for entry of streptomycin and gentamicin in susceptible and resistant bacteria
    • Bryan LE, van den Elzen HM. Effects of Membrane-energy mutations and cations on streptomycin and gentamicin accumulation by bacteria: a model for entry of streptomycin and gentamicin in susceptible and resistant bacteria. Antimicrob Agents Chemother 1977;12:163-177.
    • (1977) Antimicrob Agents Chemother , vol.12 , pp. 163-177
    • Bryan, L.E.1    Van den Elzen, H.M.2
  • 82
    • 0027418821 scopus 로고
    • Characterization of the channel formed by the mycobacterial porin in lipid bilayer membranes
    • Trias J, Benz R. Characterization of the channel formed by the mycobacterial porin in lipid bilayer membranes. J Biol Chem 1993;268:6234-6240.
    • (1993) J Biol Chem , vol.268 , pp. 6234-6240
    • Trias, J.1    Benz, R.2
  • 84
    • 76949116151 scopus 로고
    • Pyrazinamide (Aldinamide) in the treatment of pulmonary tuberculosis
    • Yeager RL, Munroe WGC, Dessau FI. Pyrazinamide (Aldinamide) in the treatment of pulmonary tuberculosis. Am Rev Tuberc 1952;65:523-534.
    • (1952) Am Rev Tuberc , vol.65 , pp. 523-534
    • Yeager, R.L.1    Munroe, W.G.C.2    Dessau, F.I.3
  • 85
    • 0000801595 scopus 로고
    • Lack of significant in vitro sensitivity of Mycobacterium tuberculosis to pyrazinamide on three different solid media
    • Tarshis MS, Weed Jr. WA. Lack of significant in vitro sensitivity of Mycobacterium tuberculosis to pyrazinamide on three different solid media. Am Rev Tuberc 1953;67:391-395.
    • (1953) Am Rev Tuberc , vol.67 , pp. 391-395
    • Tarshis, M.S.1    Weed W.A., Jr.2
  • 86
    • 77049188261 scopus 로고
    • Activation of pyrazinamide and nicotinamide in acidic environments in vitro
    • McDermott W, Tompsett R. Activation of pyrazinamide and nicotinamide in acidic environments in vitro. Am Rev Tuberc 1954;70:748-754.
    • (1954) Am Rev Tuberc , vol.70 , pp. 748-754
    • McDermott, W.1    Tompsett, R.2
  • 87
    • 0000082103 scopus 로고
    • The intracellular activation of pyrazinamide and nicotinamide
    • Mackaness GB. The intracellular activation of pyrazinamide and nicotinamide. Am Rev Tuberc Pulm Dis 1956;74:718-728.
    • (1956) Am Rev Tuberc Pulm Dis , vol.74 , pp. 718-728
    • Mackaness, G.B.1
  • 88
    • 0342503244 scopus 로고
    • The chemotherapy of pulmonary tuberculosis with pyrazinamide used alone and in combination with streptomycin, Para-aminosalicylic acid, or isoniazid
    • Schwartz WS, Moyer RE. The Chemotherapy of pulmonary tuberculosis with pyrazinamide used alone and in combination with streptomycin, Para-aminosalicylic acid, or isoniazid. Am Rev Tuberc 1954;70:413-422.
    • (1954) Am Rev Tuberc , vol.70 , pp. 413-422
    • Schwartz, W.S.1    Moyer, R.E.2
  • 89
    • 0008143578 scopus 로고
    • Further observations on pyrazinamide alone and in combination with other drugs in experimental tuberculosis
    • Steenken Jr. W, Wolinsky E, Smith MM, Montalbine V. Further observations on pyrazinamide alone and in combination with other drugs in experimental tuberculosis. Am Rev Tuberc Pulm Dis 1957;76:643-659.
    • (1957) Am Rev Tuberc Pulm Dis , vol.76 , pp. 643-659
    • Steenken W., Jr.1    Wolinsky, E.2    Smith, M.M.3    Montalbine, V.4
  • 90
    • 0025845247 scopus 로고
    • Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic
    • Crowle AJ, Dahl R, Ross E, May MH. Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic. Infect Immunol 1991;59:1823-1831.
    • (1991) Infect Immunol , vol.59 , pp. 1823-1831
    • Crowle, A.J.1    Dahl, R.2    Ross, E.3    May, M.H.4
  • 92
    • 0029954860 scopus 로고    scopus 로고
    • Mutations in pncA, a gene encoding pyrazinamidase, nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus
    • Scorpio A, Zhang Y. Mutations in pncA, a gene encoding pyrazinamidase, nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus. Nature Med 1996;2:662-7.
    • (1996) Nature Med , vol.2 , pp. 662-667
    • Scorpio, A.1    Zhang, Y.2
  • 93
    • 0014062867 scopus 로고
    • Pyrazinamide susceptibility and amidase activity of tubercle bacilli
    • Konno K, Feldmann FM, McDermott W. Pyrazinamide susceptibility and amidase activity of tubercle bacilli. Am Rev Respir Dis 1967;95:461-469.
    • (1967) Am Rev Respir Dis , vol.95 , pp. 461-469
    • Konno, K.1    Feldmann, F.M.2    McDermott, W.3
  • 94
    • 0003190187 scopus 로고
    • Effect of ethambutol on nucleic acid metabolism in Mycobacterium smegmatis and its reversal by polyamines and divalent cations
    • Forbes M, Kuck NA, Peets EA. Effect of ethambutol on nucleic acid metabolism in Mycobacterium smegmatis and its reversal by polyamines and divalent cations. J Bacteriol 1965;89:1299-1305.
    • (1965) J Bacteriol , vol.89 , pp. 1299-1305
    • Forbes, M.1    Kuck, N.A.2    Peets, E.A.3
  • 95
    • 0017361343 scopus 로고
    • Effect of ethambutol on the viable cell count in Mycobacterium smegmatis
    • Kilburn JO, Greenberg J. Effect of ethambutol on the viable cell count in Mycobacterium smegmatis. Antimicrob Agents Chemother 1977;11:534-540.
    • (1977) Antimicrob Agents Chemother , vol.11 , pp. 534-540
    • Kilburn, J.O.1    Greenberg, J.2
  • 96
    • 0024431530 scopus 로고
    • Inhibition of synthesis of arabinogalactan by ethambutol in Mycobacterium smegmatis
    • Takayama K, Kilburn JO. Inhibition of synthesis of arabinogalactan by ethambutol in Mycobacterium smegmatis. Antimicrob Agents Chemother 1989;33:1493-1499.
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 1493-1499
    • Takayama, K.1    Kilburn, J.O.2
  • 97
    • 0024993025 scopus 로고
    • Cell wall and membrane changes associated with ethambutol resistance in Mycobacterium tuberculosis H37Ra
    • Sareen M, Khuller GK. Cell Wall and membrane changes associated with ethambutol resistance in Mycobacterium tuberculosis H37Ra. Antimicrob Agents Chemother 1990;34:1773-1776.
    • (1990) Antimicrob Agents Chemother , vol.34 , pp. 1773-1776
    • Sareen, M.1    Khuller, G.K.2
  • 100
    • 0029908204 scopus 로고    scopus 로고
    • The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug elhambutal
    • Belanger AE, Besra GS, Ford ME, Mikusovak, Belisle JT, Brennan PJ, Inanuke JM. The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug elhambutal. Proc Natl Acad Sci USA 1996;93:11919-11924.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11919-11924
    • Belanger, A.E.1    Besra, G.S.2    Ford, M.E.3    Mikusovak, B.J.T.4    Brennan, P.J.5    Inanuke, J.M.6
  • 102
    • 0030041117 scopus 로고    scopus 로고
    • Structure-activity relationships of the quinolone antibacterials against mycobacteria: Effect of structural changes at N-1 and C-7
    • Renau TE, Sanchcz JP, Gage JW, Dever JA, Shapiro MA, Gracheck SJ, et al. Structure-activity relationships of the quinolone antibacterials against mycobacteria: effect of structural changes at N-1 and C-7. J Med Chem 1996;39:729-35.
    • (1996) J Med Chem , vol.39 , pp. 729-735
    • Renau, T.E.1    Sanchcz, J.P.2    Gage, J.W.3    Dever, J.A.4    Shapiro, M.A.5    Gracheck, S.J.6
  • 103
    • 0022611093 scopus 로고
    • Comparative in vitro activities of ciprofloxacin and other 4-quinolones against Mycobacterium tuberculosis and Mycobacterium intracellulare
    • Fenlon CH, Cynamon MH. Comparative in vitro activities of ciprofloxacin and other 4-quinolones against Mycobacterium tuberculosis and Mycobacterium intracellulare. Antimicrob Agents Chemother 1986;29:386-388.
    • (1986) Antimicrob Agents Chemother , vol.29 , pp. 386-388
    • Fenlon, C.H.1    Cynamon, M.H.2
  • 105
    • 0027236230 scopus 로고
    • Susceptibility of Mycobacterium kansasii to ofloxacin, sparfloxacin, clarithromycin, azithromycin, and fusidic acid
    • Witzig RS, Franzblau SG. Susceptibility of Mycobacterium kansasii to ofloxacin, sparfloxacin, clarithromycin, azithromycin, and fusidic acid. Antimicrob Agents Chemother 1993;37:1997-1999.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 1997-1999
    • Witzig, R.S.1    Franzblau, S.G.2
  • 107
    • 0002516115 scopus 로고
    • Mechanisms of quinolone action and bacterial killing
    • Hooper DC and Wolfson JS (eds). American Society for Microbiology, Washington, D.C.
    • Hooper DC, Wolfson JS. Mechanisms of quinolone action and bacterial killing. In: Hooper DC and Wolfson JS (eds) Quinolone Antimicrobial Agents. American Society for Microbiology, Washington, D.C., 1993:53-76.
    • (1993) Quinolone Antimicrobial Agents , pp. 53-76
    • Hooper, D.C.1    Wolfson, J.S.2
  • 108
    • 0026071883 scopus 로고
    • 4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified using the polymerase chain reaction
    • Oram M, Fisher LM. 4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified using the polymerase chain reaction. Antimicrob Agents Chemother 1991;35:387-389.
    • (1991) Antimicrob Agents Chemother , vol.35 , pp. 387-389
    • Oram, M.1    Fisher, L.M.2
  • 109
    • 0026692159 scopus 로고
    • Detection of gyrA gene mutations associated with ciprofloxacin resistance in methicillin resistant Staphylococcus aureus: Analysis by polymerase chain reaction and direct DNA sequencing
    • Goswitz JJ, Willard KE, Fasching CE, Peterson LR. Detection of gyrA gene mutations associated with ciprofloxacin resistance in methicillin resistant Staphylococcus aureus: analysis by polymerase chain reaction and direct DNA sequencing. Antimicrob Agents Chemother 1992;36:1166-1169.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 1166-1169
    • Goswitz, J.J.1    Willard, K.E.2    Fasching, C.E.3    Peterson, L.R.4
  • 112
    • 0028299121 scopus 로고
    • Cloning and nucleotide sequence of the Mycobacterium tuberculosis gyrA and gyrB genes, and characterization of quinolone resistance mutations
    • Takiff HE, Salazar L, Guerrero C, Huang WM, Kreisworth B, Cole S et al. Cloning and nucleotide sequence of the Mycobacterium tuberculosis gyrA and gyrB genes, and characterization of quinolone resistance mutations. Antimicrob Agents Chemother 1994;38:773-780.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 773-780
    • Takiff, H.E.1    Salazar, L.2    Guerrero, C.3    Huang, W.M.4    Kreisworth, B.5    Cole, S.6
  • 113
    • 0028339849 scopus 로고
    • Selection of a gyrA mutant of Mycobacterium tuberculosis resistant to fluoroquinolones during treatment with ofloxacin
    • published erratum appears in J Infect Dis 1994;170:1351
    • Cambau E, Sougakoff W, Besson M, Truffot PC, Grosset J, Jarlier V. Selection of a gyrA mutant of Mycobacterium tuberculosis resistant to fluoroquinolones during treatment with ofloxacin (published erratum appears in J Infect Dis 1994;170:1351). J Infect Dis 1994;170:479-83.
    • (1994) J Infect Dis , vol.170 , pp. 479-483
    • Cambau, E.1    Sougakoff, W.2    Besson, M.3    Truffot, P.C.4    Grosset, J.5    Jarlier, V.6
  • 115
    • 0028849122 scopus 로고
    • Intracellular accumulation of norfloxacin in Mycobacterium smegmatis
    • Corti S, Chevalier J, Cremieux A. Intracellular accumulation of norfloxacin in Mycobacterium smegmatis. Antimicrob Agents Chemother 1995;39:2466-2471.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2466-2471
    • Corti, S.1    Chevalier, J.2    Cremieux, A.3
  • 116
    • 0030013072 scopus 로고    scopus 로고
    • Active efflux of fluoroquinolones in Mycobacterium smegmatis mediated by lfrA, a multidrug efflux pump
    • Liu J, Takiff HE, Nikaido H. Active efflux of fluoroquinolones in Mycobacterium smegmatis mediated by lfrA, a multidrug efflux pump. J Bacteriol 1996;178:3791-3795.
    • (1996) J Bacteriol , vol.178 , pp. 3791-3795
    • Liu, J.1    Takiff, H.E.2    Nikaido, H.3
  • 117
    • 0030058375 scopus 로고    scopus 로고
    • Efflux pumps of the proton antiporter family confers low level fluoroquinolone resistance in M. smegmatis
    • Takiff HE, Cimino M, Musso MC, Weisbrod T, Martinez R, Delgado MB, et al. Efflux pumps of the proton antiporter family confers low level fluoroquinolone resistance in M. smegmatis. Proc Natl Acad Sci USA 1996;93:362-366.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 362-366
    • Takiff, H.E.1    Cimino, M.2    Musso, M.C.3    Weisbrod, T.4    Martinez, R.5    Delgado, M.B.6
  • 118
    • 23444456920 scopus 로고
    • Prevention of drug access to bacterial targets: Permeability barriers and active efflux
    • Nikaido H. Prevention of drug access to bacterial targets: Permeability barriers and active efflux. Science 1994;264:382-388.
    • (1994) Science , vol.264 , pp. 382-388
    • Nikaido, H.1
  • 119
    • 0026588343 scopus 로고
    • Active efflux mechanisms for antimicrobial resistance
    • Levy SB. Active efflux mechanisms for antimicrobial resistance. Antimicrob Agents Chemother 1992;36:695-703.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 695-703
    • Levy, S.B.1
  • 120
    • 0028365052 scopus 로고
    • Implications of multidrug-resistance for the future of short-course chemotherapy of tuberculosis: A molecular study
    • Heym B, Honoré N, Truffot-Pernot C, Banerjee A, Schurra C, Jacobs Jr. WR, et al. Implications of Multidrug-Resistance for the Future of Short-Course Chemotherapy of Tuberculosis: A Molecular Study. Lancet 1994;344:293-298.
    • (1994) Lancet , vol.344 , pp. 293-298
    • Heym, B.1    Honoré, N.2    Truffot-Pernot, C.3    Banerjee, A.4    Schurra, C.5    Jacobs W.R., Jr.6
  • 121
    • 0028955432 scopus 로고
    • Molecular mechanisms of multiple drug resistance in clinical isolates of Mycobacterium tuberculosis
    • Morris S, Bai G, Suffys P, Portillo-Gomez L, Fairchok M, Rouse D. Molecular mechanisms of multiple drug resistance in clinical isolates of Mycobacterium tuberculosis. J Infect Dis 1995;171:954-60.
    • (1995) J Infect Dis , vol.171 , pp. 954-960
    • Morris, S.1    Bai, G.2    Suffys, P.3    Portillo-Gomez, L.4    Fairchok, M.5    Rouse, D.6
  • 122
    • 0027473496 scopus 로고
    • Treatment of 171 patients with pulmonary tuberculosis resistant to isoniazid and rifampin
    • Goble M, Iseman MD, Madsen LA, Waite D, Ackerson L, Horsburgh R. Treatment of 171 patients with pulmonary tuberculosis resistant to isoniazid and rifampin. N Engl J Med 1993;328:527-532.
    • (1993) N Engl J Med , vol.328 , pp. 527-532
    • Goble, M.1    Iseman, M.D.2    Madsen, L.A.3    Waite, D.4    Ackerson, L.5    Horsburgh, R.6
  • 123
    • 0027912966 scopus 로고
    • Treatment of multidrug-resistant tuberculosis
    • Iseman MD. Treatment of multidrug-resistant tuberculosis. N Engl J Med 1993;329:784-791.
    • (1993) N Engl J Med , vol.329 , pp. 784-791
    • Iseman, M.D.1


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