How does alendronate inhibit protein-tyrosine phosphatases?

Journal of Biological Chemistry

Volumn 272, Issue 36, 1997, Pages 22472-22480

  Skorey, Kathryn ^a   Ly, Hoa D ^a   Kelly, John ^a   Hammond, Mike ^a   Ramachandran, Chidambaram ^a   Huang, Zheng ^a   Gresser, Michael J ^a   Wang, Qingping ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; CALCIUM; CD45 ANTIGEN; CYSTEINE; HYDROGEN PEROXIDE; PROTEIN TYROSINE PHOSPHATASE;

ARTICLE; DRUG MECHANISM; ENZYME INHIBITION; ENZYME KINETICS; INHIBITION KINETICS; MASS SPECTROMETRY; OXIDATION; PRIORITY JOURNAL;

ALENDRONATE; BINDING SITES; CALCIUM; CATALASE; CATALYSIS; CYSTEINE; ENZYME INHIBITORS; ENZYME REACTIVATORS; HYDROGEN PEROXIDE; KINETICS; OXIDATION-REDUCTION; PROTEIN-TYROSINE-PHOSPHATASE;

EID: 0030931795     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.36.22472     Document Type: Article

References (41)

1. Sato, M., Grasser, W., Endo, N., Akins, R., Simmons, H., Thompson, D. D., Golub, E., and Rodan, G. A. (1991) J. Clin. Invest. 88, 2095-2105
2. Rodan, G. A. (1994) Annu. Rep. Med. Chem. 29, 275-285
3. Gatti, D., Zamberlan, N., Braga, V., Dorizzi, R., Adami, S., and Rossini, M. (1994) J. Bone Miner. Res. 9, 1833-1837
4. Kanis, J. A., Gertz, B. J., Singer, F., and Ortolani, S. (1995) Osteoporosis Int. 5, 1-13
5. Liberman, U. A., Weiss, S. R., Broll, J., Minne, H. W., Quan, H., Bell, N. H., Rodriguez-Portales, J., Downs, R. W., Jr., Dequeker, J., Favus, M., Seeman, E., Recker, R. R., Capizzi, T., Santora, A. C., II, Lombardi, A., Shah, R. V., Hirsch, L. J., and Karpf, D. B. (1995) N. Engl. J. Med. 333, 1437-1443
6. Siris, E., Weinstein, R. S., Altman, R., Conte, J. M., Favus, M., Lombardi, A., Lyles, K., McIlwain, H., Murphy, W. A., Jr., Reda, C., Rude, R., Seton, M., Tiegs, R., Thompson, D., Tucci, J. R., Yates, A. J., and Zimering, M. (1996) J. Clin. Endocrinol. & Metab. 81, 961-967
7. Rodan, G. A., and Fleisch H. A. (1996) J. Clin. Invest. 97, 2692-2696
8. Gresser, M. J., Tracey, A. S., and Stankiewicz, P. J. (1987) Adv. Protein Phosphatases 4, 35-37
9. Krieger, N. S., and Tashjian, A. H. D., Jr. (1983) Endocrinology 113, 324-328
10. Neel, B. G., and Tonks, N. K. (1997) Curr. Opin. Cell Biol. 9, 193-204
11. Stone, R. L., and Dixon, J. E. (1994) J. Biol. Chem. 269, 31323-31326
12. Sun, H., and Tonks, N. K. (1994) Trends Biochem. Sci. 19, 480-485
13. Guan, K. L., and Dixon, J. E. (1991) J. Biol. Chem. 266, 17026-17030
14. Schmidt, A., Rutledge, S. J., Endo, N., Opas, E. E., Tanaka, H., Wesolowski, G., Leu, C. T., Huang, Z., Ramachandran, C., Sevgi, B. R., and Rodan, G. A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 3068-3073
15. Endo, N., Rutledge, S. J., Opas, E. E., Vogel, R., Rodan, G. A., and Schmidt, A. (1996) J. Bone Miner. Res. 11, 535-543
16. Wang, Q., Janzen, N., Ramachandran, C., and Jirik, F. (1997) Biochem. Pharmacol., in press
17. Huyer, G., Liu, S., Kelly, J., Moffat, J., Payette, P., Kennedy, B., Tsaprailis, G., Gresser, M. J., and Ramachandran, C. (1997) J. Biol. Chem. 272, 843-851
18. Masarachia, P., Weinreb, M., Balena, R., and Rodan, G. A. (1996) Bone (Elmsford) 19, 281-290
19. Zhang, Z.-Y., Maclean, D., Thieme-Selfer, A. M., Roeske, R. W., and Dixon, J. E. (1993) Anal. Chem. 211, 7-15
20. Haugland, R. P. (1992-1994) in Handbook of Fluorescent Probes and Research Chemicals (Larison, K., ed) 5th Ed., pp. 115-119, Molecular Probes, Inc. Eugene, OR
21. Mevkh, A. T., Sudina, G. F., Golub, N. B., and Varfolomeev, S. D. (1985) Anal. Biochem. 150, 91-96
22. Nardelli, N., and Pelizzi, G. (1983) Inorg. Chim. Acta 80, 259-271
23. Lamson, M. L., Fox, J. L., and Higuchi, W. I. (1984) Int. J. Pharm. (Amst.) 21, 143-154
24. Ostovic, D., Stelmach, C., and Hulshizer, B. (1993) Pharmacol. Res. 10, 470-472
25. Kitz, R., and Wilson, I. B. (1962) J. Biol. Chem. 237, 3245-3249
26. Percival, M. D., Denis, D., Riendeau, D., and Gresser, M. J. (1992) Eur. J. Biochem. 210, 109-117
27. Costa, M., Pecci, L., Pensa, B., and Cannella, C. (1977) Biochem. Biophys. Res. Commun. 78, 596-603
28. Sawyer, D. T., Sobkowiak, A., and Matsushita, T. (1996) Acc. Chem. Res. 29, 409-416
29. Trotta, P. P., Pinkus, L. M., and Meister, A. (1974) J. Biol. Chem. 249, 1915-1921
30. Stankiewicz, P. J., Gresser, M. J., Tracey, A. S., and Mass, L. F. (1987) Biochemistry 26, 1264-1269
31. Allison, W. S. (1976) Acc. Chem. Res. 9, 293-299
32. Dowson, R. M. C., Elliott, D. C., Elliott, W. H., and Jones, K. M. (1987) Data for Biochemical Research, 3rd Ed., pp. 404-407, Oxford University Press, Oxford
33. Zhao, F., Yang, J., and Schoneich, C. (1996) Pharmacol. Res. 13, 931-938
34. Suzuki, Y. J., Forman, H. J., and Sevanian, A. (1997) Free Radical Biol. & Med. 22, 269-285
35. Vepa, S., Scribner, W. M., and Natarajan, V. (1997) Free Radical Biol. & Med. 22, 25-35
36. Monteiro, H. P., and Stern, A. (1996) Free Radical Biol. & Med. 21, 323-333
37. Burdon, R. H., and Rice-Evans, C. (1989) Free Radical Res. Commun. 6, 345-348
38. Shibanuma, M., Kuroki, T., and Nose, M. (1988) Oncogene 3, 17-21
39. Gallagher, K. E., Betteridge, L. J., Patel, M. K., and Schacter, M. (1993) Biochem. Soc. Trans. 21, 98 (abstr.)
40. Taher, M. M., and Abd-Elfattah, A. S. A. (1996) Mol. Biol. Int. 40, 159-171
41. Nakamura, K, Hori, T., Sato, N., Sugie, K., Kawakami, T., and Yodoi, J. (1993) Oncogene 8, 3133-3139