Embryonic morphogenesis signaling pathway mediated by JNK targets the transcriptions factor JUN and the TGF-β homologue decapentaplegic

Journal of Cellular Biochemistry

Volumn 67, Issue 1, 1997, Pages 1-12

  Sluss, Hayla K ^a   Davis, Roger J ^a,b  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Dorsal closure signaling pathway; DPP; Drosophila; JNK pathway; Mutations

Indexed keywords

PROTEIN KINASE; TRANSCRIPTION FACTOR;

ARTICLE; CELL MIGRATION; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; GENE MUTATION; GENE STRUCTURE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ACTIVATING TRANSCRIPTION FACTOR 2; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DROSOPHILA; DROSOPHILA PROTEINS; ECTODERM; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; GENETIC COMPLEMENTATION TEST; INSECT PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOGENESIS; POINT MUTATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-JUN; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030931380     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19971001)67:1<1::AID-JCB1>3.0.CO;2-1     Document Type: Article

References (51)

1. Adler V, Polotskaya A, Wagner F, Kraft AS (1992): Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity. J Biol Chem 267:17001-17005.
2. Adler V, Unlap T, Kraft AS (1994): A peptide encoding the c-Jun δ domain inhibits the activity of a c-Jun amino-terminal protein kinase. J Biol Chem 269:11186-11191.
3. Affolter M, Nellen D, Nussbaumer U, Basler K (1994): Multiple requirements for the receptor serine/thronine kinase thick veins reveal novel functions of TGFβ homologues during Drosophila embryogenesis. Development 120:3105-3117.
4. Arora K, Dai H, Kazuko SG, Jamal J, O'Connor MB, Letsou A, Warrior R (1995): The Drosophila schnurri gene acts in the DPP/TGFβ signaling pathway and encodes a transmembrane factor homologous to the MBP family. Cell 81:781-790.
5. Ashburner M (1989): "Drosophila: A Laboratory Manual." Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
6. Brummel TJ, Twombly V, Marques G, Wrana JL, Newfeld SJ, Attisano L, Massague J, O'Connor MB, Gelbart WM (1994): Characterization and relationship of DPP receptors encoded by the saxophone and thick veins genes in Drosophila. Cell 78:251-261.
7. Dai T, Rubie E, Franklin CC, Kraft A, Gillespie DA, Avruch J, Kyriakis JM, Woodgett JR (1995): Stress-activated protein kinases bind directly to the delta domain of c-Jun in resting cells: implications for repression of c-Jun function. Oncogene 10:849-855.
8. Dérijard B, Hibi M, Wu I-H, Barrett T, Su B, Deng T, Karin M, Davis RJ (1994): JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025-1037.
9. Dérijard B, Raingeaud J, Barrett T, Wu I-H, Han J, Ulevitch RJ, Davis RJ (1995): Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267:682-685.
10. Fehon RG, Dawson IA, Artavanis-Tsakonas S (1994): A Drosophila homologue of membrane skeleton protein 4.1 is associated with sptat junctions and is encoded by th coracle gene. Development 120:545-557.
11. Glise B, Bourbon H, Noselli S (1995): hemipterous encodes a novel MAP kinase kinase required for epithelial cell sheet movement. Cell 83:451-461.
12. Grieder NC, Nellen D, Burke R, Basler K, Affolter M (1995): schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1. Cell 81:791-800.
13. Gupta S, Campbell D, Dérijard B, Davis RJ (1995): Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267:389-393.
14. Gupta S, Barrett T, Whitmarsh AJ, Sluss HK, Cavanagh J, Davis RJ (1996): Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J 15: 2760-2770.
15. Harden N, Loh HY, Chia W, Lim L (1995): A dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental shape changes in Drosophila. Development 121:903-914.
16. Harden N, Lee J, Loh H-Y, Ong Y-M, Tan I, Leung T, Manser E, Lim L (1996): A Drosophila homolog of the Rac-and Cdc42-activated serine/theonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures. Mol Cell Biol 16:1896-1980.
17. Hibi M, Lin A, Smeal T, Minden A, Karin M (1993): Identification of an oncoprotein-and UV-responsive protein kinase that bind and potentiate the c-Jun activation domain. Genes Dev 7:2135-2148.
18. Hursch DA, Padgeett RW, Gelbart WM (1993): Cross regulation of decapentaplegic and utlrabithorax transcription in the embryonic mesoderm of Drosophila. Development 117:1211-1222.
19. Immerglück K, Lawrence PA, Bienz M (1990): Induction across germ layers in Drosophila mediated by a genetic cascade. Cell 62:261-268.
20. Irish VF, Gelbart WM (1987): The decapentaplegic gene is required for dorsal-ventral patterning in the Drosophila embryo. Genes Dev 1:868-879.
21. Jackson PD, Hoffmann FM (1994): Embryonic expression patterns of the Drosophila decapentaplegic gene: Separate regulatory elements control blastoderm expression and lateral ectoderm expression. Dev Dynam 199:28-44.
22. Jurgens G, Weischaus E, Nusslein-Volhard C, Kluding H (1984): Mutations affecting the pattern of the larval cuticle in Drosophila melonagaster II. Zygotic loci on the third chromosome. Rouxs Arch Dev Biol 193:283-295.
23. Kallunki T, Su B, Tsigelny I, Sluss HK, Dérijard B, Moore G, Davis RJ, Karin M (1994): JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation. Genes Dev 8:2996-3007.
24. Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad MF, Avruch J, Woodgett JR (1994): The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369:156-160.
25. Leptin M (1995): Drosophila gastrulation: From pattern formation to morphogenesis. Annu Rev Cell Dev Biol 11:189-212.
26. Letsou A, Arora K, Wrana JL, Simin K, Twombly V, Jamal J, Staehling-Hampton K, Hoffmann FM, Gelbart WM, Massague J, O'Connor MB (1995): Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGF-β receptor family. Cell 80:899-908.
27. Lin A, Minden A, Martinetto H, Claret F-X, Lange-Carter C, Mercurio F, Johnson GL, Karin M (1995): Identification of a dual specificity kinase that activates Jun kinases and p38-Mpk2. Science 268:286-290.
28. Livingstone C, Patel G, Jones N (1995): ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J 14:1785-1797.
29. MacKrell AJ, Blumberg B, Haynes SR, Fessler JH (1988): The lethal myosperoid gene of Drosophila encodes a membrane protein homologous to vertebrate integrin beta subunits. Proc Natl Acad Sci USA 85:2633-2637.
30. Panganiban GEF, Reuter R, Scott MP, Hoffmann FM (1990): A Drosophila growth factor homolog, decapentaplegic, regulates homeotic gene expression within and across germ layers during midgut morphogenesis. Development 110:1041-1050.
31. Perkins KK, Admon A, Patel N, Tijan R (1990): The Drosophila Fos-related transcription factor AP-1 protein is a developmentally regulated transcription factor. Genes Dev 4:822-834.
32. Perkins KK, Dailey GM, Tijan R (1988): Novel Jun-and Fos-related proteins in Drosophila are functionally homologous to enhancer factor AP-1. EMBO J 13:4265-4273.
33. Ramain P, Heitzler P, Haenlin M, Simpson P (1993): pannier, a negative regulator of achaete and scute in Drosophila, encodes a zinc finger protein with homology to the vertebrate transcription factor GATA-1. Development 119:1277-1291.
34. Ray R, Arora K, Nüsslein-Volhard C, Gelbart WM (1991): The control of cell fate along the dorsal ventral axis of the Drosophila embryo. Development 113:35-54.
35. Reuter R, Panganiban GEF, Hoffmann FM, Scott MP (1990): Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos. Development 110:1031-1040.
36. Riesgo-Escovar JR, Jenni M, Fritz A, Hafen E (1996): The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye. Genes Dev 10:2759-2768.
37. Ruberte E, Marty T, Nellen D, Affolter M, Basler K (1995): An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo. Cell 6341-6351.
38. Sanchez I, Hughes RT, Mayer BJ, Yee K, Woodgett JR, Avruch J, Kyriakis JM, Zon LI (1994): Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372:794-798.
39. Sluss HK, Barrett T, Dérijard B, Davis RJ (1994): Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol Cell Biol 14:8376-8384.
40. Sluss HK, Han Z, Davis RJ, Ip YT (1996): A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila. Genes Dev 10:2745-2758.
41. Staehling-Hampton K, Laughon AS, Hoffmann FM (1995): A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling. Development 121:3393-3403.
42. Strutt DI, Weber U, Mlodzik M (1997): The role of RhoA in tissue polarity and Frizzled signaling. Nature 387:292-295.
43. Tournier C, Whitmarsh AJ, Cavanagh J, Barrett T, Davis RJ (1997): MAP kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase. Proc Natl Acad Sci USA 94:7337-7342.
44. Treier M, Bohmann D, Mlodzik M (1995): JUN cooperates with the ETS domain protein pointed to induce photoreceptor R7 fate in the Drosophila eye. Cell 83:753-760.
45. Twombly V, Blackman RK, Jin H, Graff JM, Padgett RW, Gelbart WM (1996): The TGF-β signaling pathway is essential for Drosophila oogenesis. Development 122: 1555-1565.
46. van Dam H, Wilhelm D, Herr I, Steffen A, Herrlich P, Angel P (1995): ATF2 is preferentially activated by stress-activated protein kinases to mediate c-Jun induction in response to genotoxic agents. EMBO J 14:1798-1811.
47. Whitmarsh AJ, Davis RJ (1996): Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. J Mol Med 74:589-607.
48. Winick J, Abel T, Leonard MW, Michelson I, Chardon-Loriaux, Holmgren RA, Maniatis T, Engel JD (1993): A GATA family transcription factor is expressed along the embryonic dorsoventral axis in Drosophila melonagaster. Development 119:1055-1065.
49. 2-terminal kinase activation, and defects in AP-1 transcriptional activity. Proc Natl Acad Sci USA 94:3004-3009.
50. Young P, Richman AM, Ketchum AS, Kiehart DP (1993): Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function. Genes Dev 7:29-41.
51. Zhang K, Chaillet JR, Perkins LA, Halazonetis TD, Perrimon N (1990): Drosophila homolog of the mammalian jun oncogene is expressed during embryonic development and activates transcription in mammalian cells. Proc Natl Acad Sci USA 87:6281-6285.