메뉴 건너뛰기




Volumn 13, Issue 3, 1997, Pages 127-138

Islet antigen-specific T cell clones in autoimmune diabetes: From mice to men

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; T LYMPHOCYTE ANTIGEN;

EID: 0030924123     PISSN: 07424221     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0895(199709)13:3<127::AID-DMR192>3.0.CO;2-A     Document Type: Review
Times cited : (14)

References (94)
  • 1
    • 0020067836 scopus 로고
    • Neonatal thymectomy prevents spontaneous diabetes mellitus in BB/W rat
    • Like AA, Kislauskis E, Williams RM, and Rossini AA: Neonatal thymectomy prevents spontaneous diabetes mellitus in BB/W rat. Science 216: 644-646, 1982.
    • (1982) Science , vol.216 , pp. 644-646
    • Like, A.A.1    Kislauskis, E.2    Williams, R.M.3    Rossini, A.A.4
  • 2
    • 0027958044 scopus 로고
    • Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice
    • Chatenoud L, Thervet E, Primo J, and Bach JF: Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice. Proc Natl Acad Sci USA 91: 123-127, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 123-127
    • Chatenoud, L.1    Thervet, E.2    Primo, J.3    Bach, J.F.4
  • 3
    • 0023903295 scopus 로고
    • Immunotherapy of the nonobese diabetic mouse: Treatment with an antibody to T-helper lymphocytes
    • Shizuru JA, Taylor-Edwards C, Banks BA, Gregory AK, and Fathman CG: Immunotherapy of the nonobese diabetic mouse: Treatment with an antibody to T-helper lymphocytes. Science 240: 659-662, 1988.
    • (1988) Science , vol.240 , pp. 659-662
    • Shizuru, J.A.1    Taylor-Edwards, C.2    Banks, B.A.3    Gregory, A.K.4    Fathman, C.G.5
  • 4
    • 0026680392 scopus 로고
    • The use of a nondepleting anti-CD4 monoclonal antibody to re-establish tolerance to beta cells in NOD mice
    • Hutchings P, Oreilly L, Parish NM, Waldmann H, and Cooke A: The use of a nondepleting anti-CD4 monoclonal antibody to re-establish tolerance to beta cells in NOD mice. Eur J Immunol 22: 1913-1918, 1992.
    • (1992) Eur J Immunol , vol.22 , pp. 1913-1918
    • Hutchings, P.1    Oreilly, L.2    Parish, N.M.3    Waldmann, H.4    Cooke, A.5
  • 6
    • 0022492875 scopus 로고
    • Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice
    • Wicker LS, Miller BJ, and Mullen Y: Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice. Diabetes 35: 855-860, 1986.
    • (1986) Diabetes , vol.35 , pp. 855-860
    • Wicker, L.S.1    Miller, B.J.2    Mullen, Y.3
  • 7
    • 0027991167 scopus 로고
    • Islet-specific T cell clones transfer diabetes to nonobese diabetic (NOD) FL mice
    • Peterson JD, Pike B, McDuffie M, and Haskins K: Islet-specific T cell clones transfer diabetes to nonobese diabetic (NOD) FL mice. J Immunol 153: 2800-2806, 1994.
    • (1994) J Immunol , vol.153 , pp. 2800-2806
    • Peterson, J.D.1    Pike, B.2    McDuffie, M.3    Haskins, K.4
  • 8
    • 0027468997 scopus 로고
    • Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice: Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-thy-la donors
    • Christianson SW, Shultz LD, and Leiter EH: Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice: Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-thy-la donors. Diabetes 42: 44-55, 1993.
    • (1993) Diabetes , vol.42 , pp. 44-55
    • Christianson, S.W.1    Shultz, L.D.2    Leiter, E.H.3
  • 9
    • 0023829859 scopus 로고
    • NOD marrow stem cells adoptively transfer diabetes to resistant (NOD × NON) F1 mice
    • Serreze DV, Leiter EH, Worthen SM, and Shultz LD: NOD marrow stem cells adoptively transfer diabetes to resistant (NOD × NON) F1 mice. Diabetes 37: 252-255, 1988.
    • (1988) Diabetes , vol.37 , pp. 252-255
    • Serreze, D.V.1    Leiter, E.H.2    Worthen, S.M.3    Shultz, L.D.4
  • 10
    • 0023544492 scopus 로고
    • Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates: Requirement for both L3T4+ and Lyt-2+ T cells
    • Bendelac A, Carnaud C, Boitard C, and Bach JF: Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates: Requirement for both L3T4+ and Lyt-2+ T cells. J Exp Med 166: 823-832, 1987.
    • (1987) J Exp Med , vol.166 , pp. 823-832
    • Bendelac, A.1    Carnaud, C.2    Boitard, C.3    Bach, J.F.4
  • 13
    • 0029837397 scopus 로고    scopus 로고
    • Perspectives in diabetes: T-cell responses to islet autoantigens in insulin-dependent diabetes mellitus. The search for the Holy Grail
    • Roep BO: Perspectives in diabetes: T-cell responses to islet autoantigens in insulin-dependent diabetes mellitus. The search for the Holy Grail. Diabetes 45: 1147-1156, 1996.
    • (1996) Diabetes , vol.45 , pp. 1147-1156
    • Roep, B.O.1
  • 14
    • 0030003418 scopus 로고    scopus 로고
    • Evidence of recurrent autoimmunity in human allogeneic islet transplantation
    • Stegall MD, Lafferty KJ, Kam I, and Gill RG: Evidence of recurrent autoimmunity in human allogeneic islet transplantation. Transplantation 61: 1272-1274, 1996.
    • (1996) Transplantation , vol.61 , pp. 1272-1274
    • Stegall, M.D.1    Lafferty, K.J.2    Kam, I.3    Gill, R.G.4
  • 15
    • 0026565852 scopus 로고
    • Characterization of T lymphocytes infiltrating human pancreas allograft affected by isletitis and recurrent diabetes
    • Santamaria P, Nakhleh RE, Sutherland DE, and Barbosa JJ: Characterization of T lymphocytes infiltrating human pancreas allograft affected by isletitis and recurrent diabetes. Diabetes 41: 53-61, 1992.
    • (1992) Diabetes , vol.41 , pp. 53-61
    • Santamaria, P.1    Nakhleh, R.E.2    Sutherland, D.E.3    Barbosa, J.J.4
  • 17
    • 0029954214 scopus 로고    scopus 로고
    • Insulin-dependent diabetes mellitus
    • Tisch R, and McDevitt H: Insulin-dependent diabetes mellitus. Cell 89: 290-297, 1996.
    • (1996) Cell , vol.89 , pp. 290-297
    • Tisch, R.1    McDevitt, H.2
  • 18
    • 0028979331 scopus 로고
    • Escape from "horror autotoxicus": Pathogenesis and treatment of autoimmune disease
    • Steinman L: Escape from "horror autotoxicus": Pathogenesis and treatment of autoimmune disease. [Review] Cell 80: 7-10, 1995.
    • (1995) Cell , vol.80 , pp. 7-10
    • Steinman, L.1
  • 19
    • 0024954782 scopus 로고
    • Alternative self or nonself recognition of an antigen expressed in a rare cell type in transgenic mice: Implications for self-tolerance and autoimmunity
    • Hanahan D, Jolicoeur C, Alpert S, and Skowronski J: Alternative self or nonself recognition of an antigen expressed in a rare cell type in transgenic mice: Implications for self-tolerance and autoimmunity. Cold Spring Harbor Symp Quant Biol 54 Pt 2: 821-835, 1989.
    • (1989) Cold Spring Harbor Symp Quant Biol , vol.54 , Issue.2 PART , pp. 821-835
    • Hanahan, D.1    Jolicoeur, C.2    Alpert, S.3    Skowronski, J.4
  • 20
    • 0028301977 scopus 로고
    • T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus
    • Jolicoeur C, Hanahan D, and Smith KM: T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus. Proc Natl Acad Sci USA 91: 6707-6711, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6707-6711
    • Jolicoeur, C.1    Hanahan, D.2    Smith, K.M.3
  • 21
    • 12644301804 scopus 로고
    • Limiting dilution analysis of islet infiltrating and peripheral T cells in prediabetic NOD mice
    • Schloot N, Daniel D, and Wegmann D: Limiting dilution analysis of islet infiltrating and peripheral T cells in prediabetic NOD mice. Diabetologia 37 (Suppl. 1): A94, 1994.
    • (1994) Diabetologia , vol.37 , Issue.1 SUPPL.
    • Schloot, N.1    Daniel, D.2    Wegmann, D.3
  • 23
    • 0029773865 scopus 로고    scopus 로고
    • Diabetogenic T-cell clones
    • Haskins K, and Wegmann D: Diabetogenic T-cell clones. Diabetes 45: 1299-1305, 1996.
    • (1996) Diabetes , vol.45 , pp. 1299-1305
    • Haskins, K.1    Wegmann, D.2
  • 25
    • 0028914351 scopus 로고
    • Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from nod mice
    • Daniel D, Gill RG, Schloot N, and Wegmann D: Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from nod mice. Eur J Immunol 25: 1056-1062, 1995.
    • (1995) Eur J Immunol , vol.25 , pp. 1056-1062
    • Daniel, D.1    Gill, R.G.2    Schloot, N.3    Wegmann, D.4
  • 26
    • 0030935082 scopus 로고    scopus 로고
    • Altered immune response to insulin in newly diagnosed versus insulin treated patients and healthy control subjects
    • Schloot NC, Roep BO, Wegmann D, Yu L, Chase HP, Wang T, and Eisenbark GS: Altered immune response to insulin in newly diagnosed versus insulin treated patients and healthy control subjects. Diabetologia 40: 564-572.
    • Diabetologia , vol.40 , pp. 564-572
    • Schloot, N.C.1    Roep, B.O.2    Wegmann, D.3    Yu, L.4    Chase, H.P.5    Wang, T.6    Eisenbark, G.S.7
  • 27
    • 0029991807 scopus 로고    scopus 로고
    • Cellular immune response to diverse islet cell antigens in IDDM
    • Durinovic-Bello I, Hummel M, and Ziegler AG: Cellular immune response to diverse islet cell antigens in IDDM. Diabetes 45: 795-800, 1996.
    • (1996) Diabetes , vol.45 , pp. 795-800
    • Durinovic-Bello, I.1    Hummel, M.2    Ziegler, A.G.3
  • 28
    • 0030051666 scopus 로고    scopus 로고
    • HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recentonset insulin-dependent diabetes mellitus
    • Roep BO, Duinkerken G, Schreuder GM, Kolb H, de Vries RR, and Martin S: HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recentonset insulin-dependent diabetes mellitus. Eur J Immunol 26: 1285-1289, 1996.
    • (1996) Eur J Immunol , vol.26 , pp. 1285-1289
    • Roep, B.O.1    Duinkerken, G.2    Schreuder, G.M.3    Kolb, H.4    De Vries, R.R.5    Martin, S.6
  • 29
    • 0026492896 scopus 로고
    • Macrophages, T-cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus
    • Hanninen A, Jalkanen S, Salmi M, Toikkanen S, Nikolakaros G, and Simell O: Macrophages, T-cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus. J Clin Invest 90: 1901-1910, 1992.
    • (1992) J Clin Invest , vol.90 , pp. 1901-1910
    • Hanninen, A.1    Jalkanen, S.2    Salmi, M.3    Toikkanen, S.4    Nikolakaros, G.5    Simell, O.6
  • 30
    • 0028226301 scopus 로고
    • Skewed T-cell receptor usage and junctional heterogeneity among isletitis alpha beta and gamma delta T-cells in human IDDM
    • Corrected. Published erratum appears in Diabetes 43(7): 954, 1994
    • Santamaria P, Lewis C, Jessurun J, Sutherland DE, and Barbosa JJ: Skewed T-cell receptor usage and junctional heterogeneity among isletitis alpha beta and gamma delta T-cells in human IDDM. [Corrected. Published erratum appears in Diabetes 43(7): 954, 1994] Diabetes 43: 599-606, 1994.
    • (1994) Diabetes , vol.43 , pp. 599-606
    • Santamaria, P.1    Lewis, C.2    Jessurun, J.3    Sutherland, D.E.4    Barbosa, J.J.5
  • 32
    • 0027319208 scopus 로고
    • Gliadin-specific, HLA-DQ(alpha 1*0501, beta 1* 0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients
    • Lundin KE, Scott H, Hansen T, Paulsen G, Halstensen TS, Fausa O, Thorsby E, and Sollid LM: Gliadin-specific, HLA-DQ(alpha 1*0501, beta 1* 0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients. J Exp Med 178: 187-196, 1993.
    • (1993) J Exp Med , vol.178 , pp. 187-196
    • Lundin, K.E.1    Scott, H.2    Hansen, T.3    Paulsen, G.4    Halstensen, T.S.5    Fausa, O.6    Thorsby, E.7    Sollid, L.M.8
  • 33
    • 0028228509 scopus 로고
    • T cells from the peripheral blood of coeliac disease patients recognize gluten antigens when presented by HLA-DR, -DQ, or -DP molecules
    • Gjertsen HA, Sollid LM, Ek J, Thorsby E, and Lundin KE: T cells from the peripheral blood of coeliac disease patients recognize gluten antigens when presented by HLA-DR, -DQ, or -DP molecules. Scand J Immunol 39: 567-574, 1994.
    • (1994) Scand J Immunol , vol.39 , pp. 567-574
    • Gjertsen, H.A.1    Sollid, L.M.2    Ek, J.3    Thorsby, E.4    Lundin, K.E.5
  • 36
    • 0029923430 scopus 로고    scopus 로고
    • Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes
    • Tian J, Atkinson MA, Clare-Salzler M, Herschenfeld A, Forsthuber T, Lehmann PV, and Laufman DL: Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes. J Exp Med 183: 1561-1567, 1996.
    • (1996) J Exp Med , vol.183 , pp. 1561-1567
    • Tian, J.1    Atkinson, M.A.2    Clare-Salzler, M.3    Herschenfeld, A.4    Forsthuber, T.5    Lehmann, P.V.6    Laufman, D.L.7
  • 38
    • 0028007192 scopus 로고
    • Cellular immunity to a determinant common to glutamate decarboxylase and Coxsackie virus in insulin-dependent diabetes
    • Atkinson MA, Bowman MA, Campbell L, Darrow BL, Kaufman DL, and Maclaren NK: Cellular immunity to a determinant common to glutamate decarboxylase and Coxsackie virus in insulin-dependent diabetes. J Clin Invest 94: 2125-2129, 1994.
    • (1994) J Clin Invest , vol.94 , pp. 2125-2129
    • Atkinson, M.A.1    Bowman, M.A.2    Campbell, L.3    Darrow, B.L.4    Kaufman, D.L.5    Maclaren, N.K.6
  • 39
    • 0028806679 scopus 로고
    • Long-term culture of monoclonal human T lymphocytes: Models for immunosenescence?
    • Adibzadeh M, Pohla H, Rehbein A, and Pawelec G: Long-term culture of monoclonal human T lymphocytes: models for immunosenescence? Mech Ageing Dev 83: 171-183, 1995.
    • (1995) Mech Ageing Dev , vol.83 , pp. 171-183
    • Adibzadeh, M.1    Pohla, H.2    Rehbein, A.3    Pawelec, G.4
  • 40
    • 0030061894 scopus 로고    scopus 로고
    • T-cell recognition of beta-cell autoantigens in insulin-dependent diabetes mellitus
    • Kallan AA, de Vries RR, and Roep BO: T-cell recognition of beta-cell autoantigens in insulin-dependent diabetes mellitus. [Review] APMIS 104: 3-11, 1996.
    • (1996) APMIS , vol.104 , pp. 3-11
    • Kallan, A.A.1    De Vries, R.R.2    Roep, B.O.3
  • 41
    • 0030175968 scopus 로고    scopus 로고
    • Peripheral T cell clones from NOD mice specific for GAD65 peptides: Lack of islet responsiveness or diabetogenicity
    • Schloot NC, Daniel D, Norbury-Glaser M, and Wegmann DR: Peripheral T cell clones from NOD mice specific for GAD65 peptides: Lack of islet responsiveness or diabetogenicity. J Autoimmun 9: 357-363, 1996.
    • (1996) J Autoimmun , vol.9 , pp. 357-363
    • Schloot, N.C.1    Daniel, D.2    Norbury-Glaser, M.3    Wegmann, D.R.4
  • 42
    • 0030443713 scopus 로고    scopus 로고
    • The immune response to islets in experimental diabetes and insulin-dependent diabetes mellitus
    • Wegmann DR: The immune response to islets in experimental diabetes and insulin-dependent diabetes mellitus. Curr Opin Immunol 8: 860-864, 1996.
    • (1996) Curr Opin Immunol , vol.8 , pp. 860-864
    • Wegmann, D.R.1
  • 44
    • 0030026955 scopus 로고    scopus 로고
    • Imogen 38: A novel 38-kd islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient
    • Arden SD, Roep BO, Neophytou PI, Usac EF, Duinkerken G, de Vries RR, and Hutton JC: Imogen 38: A novel 38-kd islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient. J Clin Invest 97: 551-561, 1996.
    • (1996) J Clin Invest , vol.97 , pp. 551-561
    • Arden, S.D.1    Roep, B.O.2    Neophytou, P.I.3    Usac, E.F.4    Duinkerken, G.5    De Vries, R.R.6    Hutton, J.C.7
  • 45
    • 0025058568 scopus 로고
    • Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein
    • Elias D, Markovits D, Reshef T, Van der Zee R, and Cohen IR: Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein. Proc Natl Acad Sci USA 87: 1576-1580, 1990.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1576-1580
    • Elias, D.1    Markovits, D.2    Reshef, T.3    Van Der Zee, R.4    Cohen, I.R.5
  • 46
    • 0026451989 scopus 로고
    • Expression of 65kD heat-shock proteins in the inflammatory myopathies
    • Hohlfeld R, and Engel AG: Expression of 65kD heat-shock proteins in the inflammatory myopathies. Ann Neurol 32: 821-623, 1992.
    • (1992) Ann Neurol , vol.32 , pp. 821-1623
    • Hohlfeld, R.1    Engel, A.G.2
  • 47
    • 0026649346 scopus 로고
    • Heat-shock proteins in autoimmune diabetes: From causative antigen to specific therapy
    • Yang XD, and Fiege U: Heat-shock proteins in autoimmune diabetes: From causative antigen to specific therapy. Experientia 48: 650-565, 1992.
    • (1992) Experientia , vol.48 , pp. 650-1565
    • Yang, X.D.1    Fiege, U.2
  • 48
    • 0019468220 scopus 로고
    • Limiting dilution assays for the determination of immunocompetent cell frequencies
    • Taswell C: Limiting dilution assays for the determination of immunocompetent cell frequencies. J Immunol 126: 1614-1619, 1981.
    • (1981) J Immunol , vol.126 , pp. 1614-1619
    • Taswell, C.1
  • 49
    • 0025009870 scopus 로고
    • Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone
    • Haskins K, and McDuffie M: Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone. Science 249: 1433-1436, 1990.
    • (1990) Science , vol.249 , pp. 1433-1436
    • Haskins, K.1    McDuffie, M.2
  • 50
    • 0029010646 scopus 로고
    • In vivo activity and in vivo specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice
    • Healey D, Ozegbe P, Arden SD, Chandler P, Hutton JC, and Cooke A: In vivo activity and in vivo specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice. J Clin Invest 95: 2979-2985, 1995.
    • (1995) J Clin Invest , vol.95 , pp. 2979-2985
    • Healey, D.1    Ozegbe, P.2    Arden, S.D.3    Chandler, P.4    Hutton, J.C.5    Cooke, A.6
  • 51
    • 0025346694 scopus 로고
    • T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins
    • Roep BO, Arden SD, De Vries RRP, and Hutton JC: T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins. Nature 345: 632-634, 1990.
    • (1990) Nature , vol.345 , pp. 632-634
    • Roep, B.O.1    Arden, S.D.2    De Vries, R.R.P.3    Hutton, J.C.4
  • 52
    • 0029557226 scopus 로고
    • Beta-cell reactive T-cell clones from type 1 diabetes patients are not beta cell specific and recognize multiple antigens
    • Kallan AA, Roep BO, Arden SD, Hutton JC, and De Vries RRP: Beta-cell reactive T-cell clones from type 1 diabetes patients are not beta cell specific and recognize multiple antigens. J Autoimmun 8: 877-899, 1995.
    • (1995) J Autoimmun , vol.8 , pp. 877-899
    • Kallan, A.A.1    Roep, B.O.2    Arden, S.D.3    Hutton, J.C.4    De Vries, R.R.P.5
  • 53
    • 0030025159 scopus 로고    scopus 로고
    • A subtractive cloning approach to the identification of mRNAs specifically expressed in pancreatic β-cells
    • Neophytou PI, Muir EM, and Hutton JC: A subtractive cloning approach to the identification of mRNAs specifically expressed in pancreatic β-cells. Diabetes 45: 127-133, 1996.
    • (1996) Diabetes , vol.45 , pp. 127-133
    • Neophytou, P.I.1    Muir, E.M.2    Hutton, J.C.3
  • 54
    • 0029873864 scopus 로고    scopus 로고
    • T-cell epitope analysis using subtracted expression libraries (TEASEL): Application to a 38-kDa autoantigen recognized by T-cells from an insulin-dependent diabetic patient
    • Neophytou PI, Roep BO, Arden SD, Muir EI, Duinkerken G, Kallan AA, de Vries RR, and Hutton JC: T-cell epitope analysis using subtracted expression libraries (TEASEL): Application to a 38-kDa autoantigen recognized by T-cells from an insulin-dependent diabetic patient. Proc Natl Acad Sci USA 93: 2014-2018, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2014-2018
    • Neophytou, P.I.1    Roep, B.O.2    Arden, S.D.3    Muir, E.I.4    Duinkerken, G.5    Kallan, A.A.6    De Vries, R.R.7    Hutton, J.C.8
  • 55
    • 0028900485 scopus 로고
    • A diabetes-associated T-cell autoantigen maps to a telomeric locus on mouse chromosome 6
    • Dallas-Pedretti A, McDuffie M, and Haskins K: A diabetes-associated T-cell autoantigen maps to a telomeric locus on mouse chromosome 6. Proc Natl Acad Sci USA 92: 1386-1390, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1386-1390
    • Dallas-Pedretti, A.1    McDuffie, M.2    Haskins, K.3
  • 56
    • 0029966728 scopus 로고    scopus 로고
    • T-cell epitope determination
    • Waiden P: T-cell epitope determination. Curr Opin Immunol 8: 68-74, 1996.
    • (1996) Curr Opin Immunol , vol.8 , pp. 68-74
    • Waiden, P.1
  • 58
    • 0026715263 scopus 로고
    • Identification and quantification of a naturally presented peptide as recognized by cytotoxic T lymphocytes specific for an immunogenic tumor variant
    • Wallny HJ, Deres K, Faath S, Jung G, Van Pel A, Boon T, and Rammensee HG: Identification and quantification of a naturally presented peptide as recognized by cytotoxic T lymphocytes specific for an immunogenic tumor variant. Int Immunol 4: 1085-1090, 1992.
    • (1992) Int Immunol , vol.4 , pp. 1085-1090
    • Wallny, H.J.1    Deres, K.2    Faath, S.3    Jung, G.4    Van Pel, A.5    Boon, T.6    Rammensee, H.G.7
  • 59
    • 0029828854 scopus 로고    scopus 로고
    • Immunity to 60 kDa heat shock protein in autoimmune diabetes
    • Cohen IR, and Elias D: Immunity to 60 kDa heat shock protein in autoimmune diabetes. Diabetes Nutr Metab 9: 229-232, 1996.
    • (1996) Diabetes Nutr Metab , vol.9 , pp. 229-232
    • Cohen, I.R.1    Elias, D.2
  • 60
    • 4243858662 scopus 로고    scopus 로고
    • Characterization of diabetogenic, GAD65-specific T cell clones established from NOD mice
    • Schloot N, Gottlieb P, and Wegmann D: Characterization of diabetogenic, GAD65-specific T cell clones established from NOD mice. Diabetes 45: A 307, 1996.
    • (1996) Diabetes , vol.45
    • Schloot, N.1    Gottlieb, P.2    Wegmann, D.3
  • 61
    • 0030069688 scopus 로고    scopus 로고
    • Protection of nonobese diabetic mice from diabgtes by intranasal or subcutaneous administration of insulin peptide B-(9-23)
    • Daniel D, and Wegmann DR: Protection of nonobese diabetic mice from diabgtes by intranasal or subcutaneous administration of insulin peptide B-(9-23). Proc Natl Acad Sci USA 93: 956-960, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 956-960
    • Daniel, D.1    Wegmann, D.R.2
  • 62
    • 0030175881 scopus 로고    scopus 로고
    • T-cell clones to epitopes of glutamic acid decarboxylase 65 raised from normal subjects and patients with insulin-dependent diabetes
    • Lohmann T, Leslie RDG, and Londei M: T-cell clones to epitopes of glutamic acid decarboxylase 65 raised from normal subjects and patients with insulin-dependent diabetes. J Autoimmun 9: 385-389, 1996.
    • (1996) J Autoimmun , vol.9 , pp. 385-389
    • Lohmann, T.1    Leslie, R.D.G.2    Londei, M.3
  • 65
    • 0028965967 scopus 로고
    • Autoimmune versus inflammatory type 1 diabetes: A controversy?
    • Kolb H, Kolb-Bachofen V, and Roep BO: Autoimmune versus inflammatory type 1 diabetes: A controversy? Immunol Today 16: 170-172, 1995.
    • (1995) Immunol Today , vol.16 , pp. 170-172
    • Kolb, H.1    Kolb-Bachofen, V.2    Roep, B.O.3
  • 66
    • 0029030964 scopus 로고    scopus 로고
    • T helper cell subsets in insulin-dependent diabetes
    • Katz JD, Benoist C, and Mathis D: T helper cell subsets in insulin-dependent diabetes. Science 268: 1185-1188, 1995.
    • (1995) Science , vol.268 , pp. 1185-1188
    • Katz, J.D.1    Benoist, C.2    Mathis, D.3
  • 67
    • 0029030964 scopus 로고    scopus 로고
    • T helper cell subsets in insulin-dependent diabetes
    • Katz JD, Benoist C, and Mathis D: T helper cell subsets in insulin-dependent diabetes. Science 268: 1185-1188, 1996.
    • (1996) Science , vol.268 , pp. 1185-1188
    • Katz, J.D.1    Benoist, C.2    Mathis, D.3
  • 68
    • 0029053581 scopus 로고
    • CD4+ beta islet cell-reactive T cell clones that suppress autoimmune diabetes in nonobese diabetic mice
    • Akhtar I, Gold JP, Pan LY, Ferrara JL, Yang XD, Kim JI, and Tan KN: CD4+ beta islet cell-reactive T cell clones that suppress autoimmune diabetes in nonobese diabetic mice. J Exp Med 182: 87-97, 1995.
    • (1995) J Exp Med , vol.182 , pp. 87-97
    • Akhtar, I.1    Gold, J.P.2    Pan, L.Y.3    Ferrara, J.L.4    Yang, X.D.5    Kim, J.I.6    Tan, K.N.7
  • 69
    • 0027176158 scopus 로고
    • Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes
    • Harrison LC, Honeyman MC, De Aizpurua HJ, Schmidli RS, Colman PG, Tait BD, and Crom DS: Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes. Lancet 341: 1365-1369, 1993.
    • (1993) Lancet , vol.341 , pp. 1365-1369
    • Harrison, L.C.1    Honeyman, M.C.2    De Aizpurua, H.J.3    Schmidli, R.S.4    Colman, P.G.5    Tait, B.D.6    Crom, D.S.7
  • 71
    • 0030041347 scopus 로고    scopus 로고
    • The clinical significance of an autoimmune response against glutamic acid decarboxylase
    • Ellis TM, and Atkinson MA: The clinical significance of an autoimmune response against glutamic acid decarboxylase. Nature Med 2: 148-153, 1996.
    • (1996) Nature Med , vol.2 , pp. 148-153
    • Ellis, T.M.1    Atkinson, M.A.2
  • 72
    • 0028143519 scopus 로고
    • T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele
    • Tian J, Lehmann PV, and Kaufman DL: T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele. J Exp Med 180: 1979-1984, 1994.
    • (1994) J Exp Med , vol.180 , pp. 1979-1984
    • Tian, J.1    Lehmann, P.V.2    Kaufman, D.L.3
  • 73
    • 0031019620 scopus 로고    scopus 로고
    • T-cell reactivity of GAD65 peptide sequences shared with coxsackie virus protein in recent onset IDDM, post onset IDDM patients and control subjects
    • Schloot NC, Roep BO, Wegmann DR, Yu L, Wang T, and Eisenbarth GS: T-cell reactivity of GAD65 peptide sequences shared with coxsackie virus protein in recent onset IDDM, post onset IDDM patients and control subjects. Diabetologia 40: 332-338, 1997.
    • (1997) Diabetologia , vol.40 , pp. 332-338
    • Schloot, N.C.1    Roep, B.O.2    Wegmann, D.R.3    Yu, L.4    Wang, T.5    Eisenbarth, G.S.6
  • 74
    • 0017836309 scopus 로고
    • Passive transfer of diabetes mellitus from man to mouse
    • Buschard K, Madsbad S, and Rygaard J: Passive transfer of diabetes mellitus from man to mouse. Lancet 1(8070) 908-910, 1978.
    • (1978) Lancet , vol.1 , Issue.8070 , pp. 908-910
    • Buschard, K.1    Madsbad, S.2    Rygaard, J.3
  • 76
    • 0027176922 scopus 로고
    • Transfer of type-1 (insulin-dependent) diabetes mellitus associated autoimmunity to mice with severe combined immunodeficiency (SCID)
    • Petersen JS, Marshall MO, Baekkeskov S, Hejnaes KR, Hoiermadsen M, and Dyrberg T: Transfer of type-1 (insulin-dependent) diabetes mellitus associated autoimmunity to mice with severe combined immunodeficiency (SCID). Diabetologia 36: 510-515, 1993.
    • (1993) Diabetologia , vol.36 , pp. 510-515
    • Petersen, J.S.1    Marshall, M.O.2    Baekkeskov, S.3    Hejnaes, K.R.4    Hoiermadsen, M.5    Dyrberg, T.6
  • 77
    • 0028970655 scopus 로고
    • Emv30null NOD-scid mice: An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells
    • Serreze DV, Leiter EH, Hanson MS, Christianson SW, Shultz LD, Hesselton RM: Emv30null NOD-scid mice: An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells. Diabetes 44: 1392-1398, 1995.
    • (1995) Diabetes , vol.44 , pp. 1392-1398
    • Serreze, D.V.1    Leiter, E.H.2    Hanson, M.S.3    Christianson, S.W.4    Shultz, L.D.5    Hesselton, R.M.6
  • 78
    • 0029830079 scopus 로고    scopus 로고
    • HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: Definitive association with HLA-DRB1*0301 (DR3) gene
    • Kong YM, Lomo LC, Motte RW, Giraldo AA, Baisch J, Strauss G, Hämmerling GJ, and David CS: HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: Definitive association with HLA-DRB1*0301 (DR3) gene. J Exp Med 184: 1167-1172, 1996.
    • (1996) J Exp Med , vol.184 , pp. 1167-1172
    • Kong, Y.M.1    Lomo, L.C.2    Motte, R.W.3    Giraldo, A.A.4    Baisch, J.5    Strauss, G.6    Hämmerling, G.J.7    David, C.S.8
  • 79
    • 0030069688 scopus 로고    scopus 로고
    • Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)
    • Daniel D, and Wegmann D: Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23). Proc Natl Acad Sci USA 93: 956-960, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 956-960
    • Daniel, D.1    Wegmann, D.2
  • 80
    • 0026545730 scopus 로고    scopus 로고
    • Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice
    • Gerlin JC, Serreze DV, Christianson SW, and Leiter EH: Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice. Diabetes 41: 1672-1676.
    • Diabetes , vol.41 , pp. 1672-1676
    • Gerlin, J.C.1    Serreze, D.V.2    Christianson, S.W.3    Leiter, E.H.4
  • 81
    • 0028787305 scopus 로고
    • Treatment of autoimmune diabetes and insulitis in NOD mice with heat shock protein 60 peptide p277
    • Elias D, and Cohen IR: Treatment of autoimmune diabetes and insulitis in NOD mice with heat shock protein 60 peptide p277. Diabetes 44: 1132-1138, 1995.
    • (1995) Diabetes , vol.44 , pp. 1132-1138
    • Elias, D.1    Cohen, I.R.2
  • 82
    • 0026710502 scopus 로고
    • Marked dendritic cell-T cell cluster formation in the pancreatic lymph node of the non-obese diabetic mouse
    • Clare-Salzler M, and Mullen Y: Marked dendritic cell-T cell cluster formation in the pancreatic lymph node of the non-obese diabetic mouse. Immunology 76: 478-484, 1992.
    • (1992) Immunology , vol.76 , pp. 478-484
    • Clare-Salzler, M.1    Mullen, Y.2
  • 83
    • 0026094882 scopus 로고
    • Analysis of pancreas-infiltrating T-cells in diabetic NOD mice: Fusion with BW5147 yields a high frequency of islet-reactive hybridomas
    • Prud'homme GJ, Long TY, Bocarro DC, Balderas RS, and Theofilopoulos AN: Analysis of pancreas-infiltrating T-cells in diabetic NOD mice: fusion with BW5147 yields a high frequency of islet-reactive hybridomas. Autoimmunity 10: 285-289, 1991.
    • (1991) Autoimmunity , vol.10 , pp. 285-289
    • Prud'homme, G.J.1    Long, T.Y.2    Bocarro, D.C.3    Balderas, R.S.4    Theofilopoulos, A.N.5
  • 84
    • 0024947844 scopus 로고
    • An explanation for the protective effect of the MHC class II I-E molecule in murine diabetes
    • Reich EP, Sherwin RS, Kanagawa O, and Janeway CA, Jr: An explanation for the protective effect of the MHC class II I-E molecule in murine diabetes. Nature 341: 326-328, 1989.
    • (1989) Nature , vol.341 , pp. 326-328
    • Reich, E.P.1    Sherwin, R.S.2    Kanagawa, O.3    Janeway Jr., C.A.4
  • 85
    • 0029783716 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-restricted infiltration and destruction of pancreatic islets by NOD mouse derived β-cell cytotoxic CD8+ T-cell clones in vivo
    • Utsugi T, Yoon J-W, Park B, Imamura M, Averill N, Kawazu S, and Soutomenia P: Major histocompatibility complex class I-restricted infiltration and destruction of pancreatic islets by NOD mouse derived β-cell cytotoxic CD8+ T-cell clones in vivo. Diabetes 45: 1121-1131, 1996.
    • (1996) Diabetes , vol.45 , pp. 1121-1131
    • Utsugi, T.1    Yoon, J.-W.2    Park, B.3    Imamura, M.4    Averill, N.5    Kawazu, S.6    Soutomenia, P.7
  • 86
    • 13344294394 scopus 로고    scopus 로고
    • CD8 T-cell clones from young Nonobese Diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in absence of CD4 cells
    • Wong FS, Visintin I, Wen L, Flavell RA, and Janeway CA: CD8 T-cell clones from young Nonobese Diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in absence of CD4 cells. J Exp Med 183: 67-76, 1996.
    • (1996) J Exp Med , vol.183 , pp. 67-76
    • Wong, F.S.1    Visintin, I.2    Wen, L.3    Flavell, R.A.4    Janeway, C.A.5
  • 87
    • 0028574073 scopus 로고
    • HLA-DQ-restricted, islet-specific T-cell clones of a type 1 diabetic patient: T-cell receptor sequence similarities to insulitis-inducing T-cells of nonobese diabetic mice
    • Durinovic-Bello I, Steinle A, Ziegler AG, and Schendel DJ: HLA-DQ-restricted, islet-specific T-cell clones of a type 1 diabetic patient: T-cell receptor sequence similarities to insulitis-inducing T-cells of nonobese diabetic mice. Diabetes 43: 1318-1325, 1994.
    • (1994) Diabetes , vol.43 , pp. 1318-1325
    • Durinovic-Bello, I.1    Steinle, A.2    Ziegler, A.G.3    Schendel, D.J.4
  • 88
    • 0025811264 scopus 로고
    • Human islet cell induced T cell lines and clones from diabetic children
    • Kontiainen S, James RL, and Feldmann M: Human islet cell induced T cell lines and clones from diabetic children. Autoimmunity 8: 193-197, 1991.
    • (1991) Autoimmunity , vol.8 , pp. 193-197
    • Kontiainen, S.1    James, R.L.2    Feldmann, M.3
  • 89
    • 0028343830 scopus 로고
    • T cell clones generated from patients with type 1 diabetes using interleukin-2 proliferate to human islet antigens
    • Peakman M, Wen L, Mcnab GL, Watkins PJ, Tan KC, and Vergani D: T cell clones generated from patients with type 1 diabetes using interleukin-2 proliferate to human islet antigens. Autoimmunity 17: 31-39, 1994.
    • (1994) Autoimmunity , vol.17 , pp. 31-39
    • Peakman, M.1    Wen, L.2    Mcnab, G.L.3    Watkins, P.J.4    Tan, K.C.5    Vergani, D.6
  • 91
    • 0027522166 scopus 로고
    • Recognition of human insulin in the context of HLA-DRB1*0406 products by T-cells of insulin autoimmune syndrome patients and healthy donors
    • Ito Y, Nieda M, Uchigata Y, Nishimura M, Tokunaga K, Kuwata S, Obata F, Tadokoro K, Hirata K, Omori Y et al.: Recognition of human insulin in the context of HLA-DRB1*0406 products by T-cells of insulin autoimmune syndrome patients and healthy donors. J Immunol 151: 5770-5776, 1993.
    • (1993) J Immunol , vol.151 , pp. 5770-5776
    • Ito, Y.1    Nieda, M.2    Uchigata, Y.3    Nishimura, M.4    Tokunaga, K.5    Kuwata, S.6    Obata, F.7    Tadokoro, K.8    Hirata, K.9    Omori, Y.10
  • 92
    • 0023573995 scopus 로고
    • Processing and presentation of insulin. I. Analysis of immunogenic peptides and processing requirements for insulin A loop-specific T cells
    • Naquet P, Ellis J, Singh B, Hodges RS, and Delovitch TL: Processing and presentation of insulin. I. Analysis of immunogenic peptides and processing requirements for insulin A loop-specific T cells. J Immunol 139: 3955-3963, 1987.
    • (1987) J Immunol , vol.139 , pp. 3955-3963
    • Naquet, P.1    Ellis, J.2    Singh, B.3    Hodges, R.S.4    Delovitch, T.L.5
  • 93
    • 12644310898 scopus 로고    scopus 로고
    • Presentation of autoantigenic (GAD65) peptide in IDDM by an HLA allele protecting from disease
    • Bach JM, Otto H, Jung G, Nepom G, Boitard C, and van Endert PM: Presentation of autoantigenic (GAD65) peptide in IDDM by an HLA allele protecting from disease. Hum Immunol 47: 151, 1996.
    • (1996) Hum Immunol , vol.47 , pp. 151
    • Bach, J.M.1    Otto, H.2    Jung, G.3    Nepom, G.4    Boitard, C.5    Van Endert, P.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.