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1
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Definitive hematopoiesis is autonomously initiated by the AGM region
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Medvinsky A, Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell. 86:1996;897-906.
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Medvinsky, A.1
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2
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0004887468
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Lymphoid potential, probed before circulation in mouse, is restricted to caudal intraembryonic splanchnopleura
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Cumano A, Dieterlen-Lievre F, Godin I. Lymphoid potential, probed before circulation in mouse, is restricted to caudal intraembryonic splanchnopleura. Cell. 86:1996;907-916.
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Cumano, A.1
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0030045394
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B cells are generated throughout life in humans
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Nuez C, Nishimoto N, Gartland GL, Billips LG, Burrows PD, Kubagawa H, Cooper MD. B cells are generated throughout life in humans. J Immunol. 156:1996;866-872.
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Nuez, C.1
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Burrows, P.D.5
Kubagawa, H.6
Cooper, M.D.7
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4
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0028784287
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Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset
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Galy A, Travis M, Cen Z, Chen B. Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity. 3:1995;459-473.
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Galy, A.1
Travis, M.2
Cen, Z.3
Chen, B.4
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5
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0030250404
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In vitro tracking of IL-7 responsiveness and gene expression during commitment of bipotent B-cell/macrophage progenitors
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Kee BL, Paige CJ. In vitro tracking of IL-7 responsiveness and gene expression during commitment of bipotent B-cell/macrophage progenitors. Curr Biol. 6:1996;1159-1169.
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Curr Biol
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Kee, B.L.1
Paige, C.J.2
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6
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0030044169
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Self-renewal of B-1 lymphocytes is dependent on CD19
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Krop I, De Fougerolles AR, Hardy RR, Allison M, Schlissel MS, Fearon DT. Self-renewal of B-1 lymphocytes is dependent on CD19. Eur J Immunol. 26:1996;238-242.
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(1996)
Eur J Immunol
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Krop, I.1
De Fougerolles, A.R.2
Hardy, R.R.3
Allison, M.4
Schlissel, M.S.5
Fearon, D.T.6
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7
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0029930417
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Assembly of the truncated immunoglobulin heavy chain Dμ into antigen receptor-like complexes in pre-B cells but not in B cells
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Home MC, Roth PE, DeFranco AL. Assembly of the truncated immunoglobulin heavy chain Dμ into antigen receptor-like complexes in pre-B cells but not in B cells. Immunity. 4:1996;145-158.
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Immunity
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Home, M.C.1
Roth, P.E.2
DeFranco, A.L.3
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8
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0030006070
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Clonal selection and learning in the antibody system
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of outstanding interest. A scholarly and timely review of the entire process of B cell differentiation from the earliest developmental stages to the production of high-affinity antibodies by plasma cells and the generation of memory cells.
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of outstanding interest Rajewsky K. Clonal selection and learning in the antibody system. Nature. 381:1996;751-758 A scholarly and timely review of the entire process of B cell differentiation from the earliest developmental stages to the production of high-affinity antibodies by plasma cells and the generation of memory cells.
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(1996)
Nature
, vol.381
, pp. 751-758
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Rajewsky, K.1
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9
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0030057473
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Fate of surrogate light chains in B lineage cells
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of special interest. Biosynthesis and assembly of Ig receptor components were compared in human pro-B and pre-B cell lines. The surrogate light chains in pro-B cells did not associate with either Igα or Igβ, underwent rapid degradation, and failed to reach the surface, whereas in pre-B cell lines surrogate LCs associated with μ HCs, Igα and Igβ, to form a stable receptor complex. Participants in this assembly process included BIP, calnexin, GRP94 and an unidentified Mr 17 000 protein.
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of special interest Lassoued K, Illges H, Benlagha K, Cooper MD. Fate of surrogate light chains in B lineage cells. J Exp Med. 183:1996;421-429 Biosynthesis and assembly of Ig receptor components were compared in human pro-B and pre-B cell lines. The surrogate light chains in pro-B cells did not associate with either Igα or Igβ, underwent rapid degradation, and failed to reach the surface, whereas in pre-B cell lines surrogate LCs associated with μ HCs, Igα and Igβ, to form a stable receptor complex. Participants in this assembly process included BIP, calnexin, GRP94 and an unidentified Mr 17 000 protein.
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(1996)
J Exp Med
, vol.183
, pp. 421-429
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-
Lassoued, K.1
Illges, H.2
Benlagha, K.3
Cooper, M.D.4
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10
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-
0029741691
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Assembled pre-B cell receptor complexes are retained in the endoplasmic reticulum by a mechanism that is not selective for the pseudo-light chain
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Brouns GS, De Vries E, Neefjes JJ, Borst J. Assembled pre-B cell receptor complexes are retained in the endoplasmic reticulum by a mechanism that is not selective for the pseudo-light chain. J Biol Chem. 271:1996;19272-19278.
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(1996)
J Biol Chem
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, pp. 19272-19278
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Brouns, G.S.1
De Vries, E.2
Neefjes, J.J.3
Borst, J.4
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11
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0028670390
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Apotosis and macrophage-mediated cell deletion in the regulation of B lymphopoiesis in mouse bone marrow
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Osmond DG, Rico-Vargas S, Valenzona H, Fauteux L, Liu L, Janani R, Lu L, Jacobsen K. Apotosis and macrophage-mediated cell deletion in the regulation of B lymphopoiesis in mouse bone marrow. Immunol Rev. 142:1994;209-230.
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(1994)
Immunol Rev
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Osmond, D.G.1
Rico-Vargas, S.2
Valenzona, H.3
Fauteux, L.4
Liu, L.5
Janani, R.6
Lu, L.7
Jacobsen, K.8
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12
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0028179068
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The expression of Vpre-Bλ5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice
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Karasuyama H, Rolink A, Shinkai Y, Young F, Alt FW, Melchers F. The expression of Vpre-Bλ5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice. Cell. 77:1994;133-143.
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(1994)
Cell
, vol.77
, pp. 133-143
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Karasuyama, H.1
Rolink, A.2
Shinkai, Y.3
Young, F.4
Alt, F.W.5
Melchers, F.6
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13
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0029913115
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Regulation of an early developmental checkpoint in the B cell pathway by Igβ
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H rearrangement. The mechanism for this earlier than anticipated developmental block is unclear.
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H rearrangement. The mechanism for this earlier than anticipated developmental block is unclear.
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(1996)
Science
, vol.272
, pp. 411-414
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Gong, S.1
Nussenzweig, M.C.2
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14
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0026652354
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A critical role of the λ5 protein in B cell development
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Kitamura D, Kudo A, Schaal S, Mller W, Melchers F, Rajewsky K. A critical role of the λ5 protein in B cell development. Cell. 69:1992;823-831.
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(1992)
Cell
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Kitamura, D.1
Kudo, A.2
Schaal, S.3
Mller, W.4
Melchers, F.5
Rajewsky, K.6
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15
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0030249394
-
A prematurely expressed Igκ transgene, but not a VκJκ gene segment targeted into the Igκ locus, can rescue B cell development in λ5-deficient mice
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of special interest. These studies address the potential role of a conventional κLC in rescuing B cell development in ΨLC-deficient mice. Rearranged κ transgenes efficiently rescued B cell development when the transgene was expressed early in B lineage development. Because the conventional κ chain is interchangeable with the ΨLC, recognition of the putative ligand for the pre-BCR does not depend on specificity endowed by the ΨLC component.
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of special interest Pelanda R, Schaal S, Torres RM, Rajewsky K. A prematurely expressed Igκ transgene, but not a VκJκ gene segment targeted into the Igκ locus, can rescue B cell development in λ5-deficient mice. Immunity. 5:1996;229-239 These studies address the potential role of a conventional κLC in rescuing B cell development in ΨLC-deficient mice. Rearranged κ transgenes efficiently rescued B cell development when the transgene was expressed early in B lineage development. Because the conventional κ chain is interchangeable with the ΨLC, recognition of the putative ligand for the pre-BCR does not depend on specificity endowed by the ΨLC component.
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(1996)
Immunity
, vol.5
, pp. 229-239
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-
Pelanda, R.1
Schaal, S.2
Torres, R.M.3
Rajewsky, K.4
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16
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0029852931
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Surrogate or conventional light chains are required for membrane immunoglobulin mu to activate the precursor B cell transition
-
of special interest. In RAG-1/ 5 double-knockout mice, membrane μ HC transgenes were unable to promote pre-B cell progression, but either λ5 or λLC transgenes could complement this deficiency thus providing direct support for the dual pathways of early B cell development.
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of special interest Papavasiliou F, Jankovic M, Nussenzweig MC. Surrogate or conventional light chains are required for membrane immunoglobulin mu to activate the precursor B cell transition. J Exp Med. 184:1996;2025-2030 In RAG-1/ 5 double-knockout mice, membrane μ HC transgenes were unable to promote pre-B cell progression, but either λ5 or λLC transgenes could complement this deficiency thus providing direct support for the dual pathways of early B cell development.
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(1996)
J Exp Med
, vol.184
, pp. 2025-2030
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Papavasiliou, F.1
Jankovic, M.2
Nussenzweig, M.C.3
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17
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0029886467
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Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development
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of special interest. This study employed single cell polymerase chain reaction analysis of VDJ rearrangements on both alleles to demonstrate allelic inclusion in early pre-B cells and allelic exclusion in B cells of λ5 knockout mice. The data indicate that pre-BCR expression can terminate the VDJ rearrangement process. Cells that pursue the alternate pathway with early LC VJ rearrangements presumably become B cells to account for the limited numbers of these cells that are generated in these mice. This paper also provides evidence for the mediation of allelic exclusion at the IgH locus by a Dμ pre-BCR.
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of special interest Lffert D, Ehlich A, Mller W, Rajewsky K. Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development. Immunity. 4:1996;133-144 This study employed single cell polymerase chain reaction analysis of VDJ rearrangements on both alleles to demonstrate allelic inclusion in early pre-B cells and allelic exclusion in B cells of λ5 knockout mice. The data indicate that pre-BCR expression can terminate the VDJ rearrangement process. Cells that pursue the alternate pathway with early LC VJ rearrangements presumably become B cells to account for the limited numbers of these cells that are generated in these mice. This paper also provides evidence for the mediation of allelic exclusion at the IgH locus by a Dμ pre-BCR.
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(1996)
Immunity
, vol.4
, pp. 133-144
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Lffert, D.1
Ehlich, A.2
Mller, W.3
Rajewsky, K.4
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18
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0029947546
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H structure of the μ surrogate L chain
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H antigen specificity is involved in positive selection of pre-B cells.
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H antigen specificity is involved in positive selection of pre-B cells.
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(1996)
EMBO J
, vol.15
, pp. 1524-1533
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Ye, J.1
McCray, S.K.2
Clarke, S.H.3
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19
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0028784187
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Surrogate light chain-dependent selection of Ig heavy chain V regions
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Keyna U, Beck-Engeser GB, Jongstra J, Applequist SE, Jäck H-M. Surrogate light chain-dependent selection of Ig heavy chain V regions. J Immunol. 155:1995;5536-5542.
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(1995)
J Immunol
, vol.155
, pp. 5536-5542
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Keyna, U.1
Beck-Engeser, G.B.2
Jongstra, J.3
Applequist, S.E.4
Jäck, H.-M.5
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20
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0025823341
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Normal pre-B cells express a receptor complex of μ heavy chains and surrogate light chain proteins
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Nishimoto N, Kubagawa H, Ohno T, Gartland GL, Stankovic AK, Cooper MD. Normal pre-B cells express a receptor complex of μ heavy chains and surrogate light chain proteins. Proc Natl Acad Sci USA. 88:1991;6284-6288.
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(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 6284-6288
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Nishimoto, N.1
Kubagawa, H.2
Ohno, T.3
Gartland, G.L.4
Stankovic, A.K.5
Cooper, M.D.6
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21
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0027400889
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Expression of surrogate light chain receptors is restricted to a late stage in pre-B-cell differentiation
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Lassoued K, Nuez CA, Billips L, Kubagawa H, Monteiro RC, LeBien TW, Cooper MD. Expression of surrogate light chain receptors is restricted to a late stage in pre-B-cell differentiation. Cell. 73:1993;1-20.
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(1993)
Cell
, vol.73
, pp. 1-20
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Lassoued, K.1
Nuez, C.A.2
Billips, L.3
Kubagawa, H.4
Monteiro, R.C.5
Lebien, T.W.6
Cooper, M.D.7
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22
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0027979949
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Discrete early pro-B and pre-B stages in normal human bone marrow as defined by surface pseudo-light chain expression
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Guelpa-Fonlupt V, Tonnelle C, Blaise D, Fougereau M, Famoux F. Discrete early pro-B and pre-B stages in normal human bone marrow as defined by surface pseudo-light chain expression. Eur J Immunol. 24:1994;257-264.
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(1994)
Eur J Immunol
, vol.24
, pp. 257-264
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-
Guelpa-Fonlupt, V.1
Tonnelle, C.2
Blaise, D.3
Fougereau, M.4
Famoux, F.5
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23
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0028935407
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Precursor B cells of mouse bone marrow express two different complexes with the surrogate light chain on the surface
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of special interest. These studies in mice confirm the earlier observation in humans of low level expression of pre-B receptors on a subpopulation of pre-B cells (pre-BII). A monoclonal antibody against free λ5 protein also stained transformed and normal pro-B and pre-BI cells and precipitated surrogate LC together with a collection of other proteins ranging from Mr 30 000 to Mr 130 000 as a surrogate HC complex.
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of special interest Winkler TH, Rolink A, Melchers F, Karasuyama H. Precursor B cells of mouse bone marrow express two different complexes with the surrogate light chain on the surface. Eur J Immunol. 25:1995;446-450 These studies in mice confirm the earlier observation in humans of low level expression of pre-B receptors on a subpopulation of pre-B cells (pre-BII). A monoclonal antibody against free λ5 protein also stained transformed and normal pro-B and pre-BI cells and precipitated surrogate LC together with a collection of other proteins ranging from Mr 30 000 to Mr 130 000 as a surrogate HC complex.
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(1995)
Eur J Immunol
, vol.25
, pp. 446-450
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-
Winkler, T.H.1
Rolink, A.2
Melchers, F.3
Karasuyama, H.4
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24
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9544223185
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Cross-linking of B cell antigen receptor-related structure of pre-B cell lines induces tyrosine phosphorylation of p85 and p110 subunits and activation of phosphatidylinositol 3-kinase
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of special interest. A comprehensive comparison of signal transduction for pre-BCR versus BCRs. The data indicate a characteristic signaling pattern for the pre-BCR complex that involves tyrosine phosphorylation of phosphatidylinositol-3 kinase and protein kinase C (α isoform) activation without detectable Syk activation and minimal calcium mobilization.
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of special interest Kuwahara K, Kawai T, Mitsuyoshi S, Matsuo Y, Kikuchi H, Imajoh-Ohmi S, Hashimoto E, Inui S, Cooper MD, Sakaguchi N. Cross-linking of B cell antigen receptor-related structure of pre-B cell lines induces tyrosine phosphorylation of p85 and p110 subunits and activation of phosphatidylinositol 3-kinase. Int Immunol. 8:1996;1273-1285 A comprehensive comparison of signal transduction for pre-BCR versus BCRs. The data indicate a characteristic signaling pattern for the pre-BCR complex that involves tyrosine phosphorylation of phosphatidylinositol-3 kinase and protein kinase C (α isoform) activation without detectable Syk activation and minimal calcium mobilization.
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(1996)
Int Immunol
, vol.8
, pp. 1273-1285
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-
Kuwahara, K.1
Kawai, T.2
Mitsuyoshi, S.3
Matsuo, Y.4
Kikuchi, H.5
Imajoh-Ohmi, S.6
Hashimoto, E.7
Inui, S.8
Cooper, M.D.9
Sakaguchi, N.10
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25
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0029893866
-
The signaling activity of murine CD19 is regulated during B cell development
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of special interest. This data laden paper demonstrates that murine CD19 shares with human CD19 an association with complement receptor CD21 and CD81, tyrosine phosphorylation, binding of phosphatidylinositol-3 kinase, and synergistic signaling with membrane IgM. Several other important observations are made in this paper. First, CD19 ligation does not activate calcium mobilization until the pre-B cell stage. Second, μ heavy chain transgenic products that promote pre-B cell progression in RAG-2 deficient mice cannot be seen on the cell surface by immunofluorescence but can be demonstrated functionally by the synergistic effect of anti-μ and anti-CD19 on calcium flux. Third, a μ heavy chain transgene deleted of its CH1 domain can function as a pre-BCR although it does not bind λ5.
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of special interest Krop I, Shaffer AL, Fearon DT, Shlissel MS. The signaling activity of murine CD19 is regulated during B cell development. J Immunol. 157:1996;48-56 This data laden paper demonstrates that murine CD19 shares with human CD19 an association with complement receptor CD21 and CD81, tyrosine phosphorylation, binding of phosphatidylinositol-3 kinase, and synergistic signaling with membrane IgM. Several other important observations are made in this paper. First, CD19 ligation does not activate calcium mobilization until the pre-B cell stage. Second, μ heavy chain transgenic products that promote pre-B cell progression in RAG-2 deficient mice cannot be seen on the cell surface by immunofluorescence but can be demonstrated functionally by the synergistic effect of anti-μ and anti-CD19 on calcium flux. Third, a μ heavy chain transgene deleted of its CH1 domain can function as a pre-BCR although it does not bind λ5.
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(1996)
J Immunol
, vol.157
, pp. 48-56
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-
Krop, I.1
Shaffer, A.L.2
Fearon, D.T.3
Shlissel, M.S.4
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26
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0029379728
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Pre-B-cell development in the absence of λ5 in transgenic mice expressing a heavy-chain disease protein
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of special interest. Expression of a truncated μ heavy chain transgene allowed pre-B cell progression in SCID mice. Interestingly, mutant μ HC (VDJ deleted) reached the pre-B cell surface in relatively high levels even in λ5-deficient SCID mice. A cell surface distribution pattern indicative of receptor aggregation may account for the constitutive activation signal delivery by the truncated μ protein.
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of special interest Corcos D, Dunda O, Butor C, Cesbron J-Y, Lors P, Bucchini D, Jami J. Pre-B-cell development in the absence of λ5 in transgenic mice expressing a heavy-chain disease protein. Curr Biol. 5:1995;1140-1148 Expression of a truncated μ heavy chain transgene allowed pre-B cell progression in SCID mice. Interestingly, mutant μ HC (VDJ deleted) reached the pre-B cell surface in relatively high levels even in λ5-deficient SCID mice. A cell surface distribution pattern indicative of receptor aggregation may account for the constitutive activation signal delivery by the truncated μ protein.
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(1995)
Curr Biol
, vol.5
, pp. 1140-1148
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-
Corcos, D.1
Dunda, O.2
Butor, C.3
Cesbron, J.-Y.4
Lors, P.5
Bucchini, D.6
Jami, J.7
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27
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0029984777
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A novel anti-Vpre-B antibody identifies immunoglobulin-surrogate receptors on the surface of human pro-B cells
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Sanz E, De la Hera A. A novel anti-Vpre-B antibody identifies immunoglobulin-surrogate receptors on the surface of human pro-B cells. J Exp Med. 183:1996;2693-2698.
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(1996)
J Exp Med
, vol.183
, pp. 2693-2698
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Sanz, E.1
De La Hera, A.2
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28
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0028821820
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The cytoplasmic domains of immunoglobulin (Ig) α and Igβ can independently induce the precursor B cell transition and allelic exclusion
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Papavasiliou F, Jankovic M, Suh H, Nussenzweig MC. The cytoplasmic domains of immunoglobulin (Ig) α and Igβ can independently induce the precursor B cell transition and allelic exclusion. J Exp Med. 182:1995;1389-1394.
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(1995)
J Exp Med
, vol.182
, pp. 1389-1394
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Papavasiliou, F.1
Jankovic, M.2
Suh, H.3
Nussenzweig, M.C.4
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29
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0030058466
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Aberrant B cell development and immune response in mice with a compromised BCR complex
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of special interest. Gene targeting was used to delete most of the cytoplasmic tail of Igα, resulting in an Igα/Igβ heterodimer that allows the assembly and transport of pre-BCRs and BCRs, but is defective for Igα-mediated signaling. B cell generation in the bone marrow was inhibited only two- to four-fold, findings consistent with those in [28], which showed that the cytoplasmic domains of Igα and Igβ can independently induce early B cell development. There was a dramatic decrease in peripheral B cells, however, suggesting a developmental checkpoint that prevents cells with defective receptors from exiting the bone marrow.
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of special interest Torres RM, Flaswinkel H, Reth M, Rajewsky K. Aberrant B cell development and immune response in mice with a compromised BCR complex. Science. 272:1996;1804-1808 Gene targeting was used to delete most of the cytoplasmic tail of Igα, resulting in an Igα/Igβ heterodimer that allows the assembly and transport of pre-BCRs and BCRs, but is defective for Igα-mediated signaling. B cell generation in the bone marrow was inhibited only two- to four-fold, findings consistent with those in [28], which showed that the cytoplasmic domains of Igα and Igβ can independently induce early B cell development. There was a dramatic decrease in peripheral B cells, however, suggesting a developmental checkpoint that prevents cells with defective receptors from exiting the bone marrow.
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(1996)
Science
, vol.272
, pp. 1804-1808
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-
Torres, R.M.1
Flaswinkel, H.2
Reth, M.3
Rajewsky, K.4
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30
-
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0030031492
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Modulation of rat B cell differentiation in vivo by the administration of an anti-μ monoclonal antibody
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Soares M, Havaux X, Nisol F, Baxin H, Latinne D. Modulation of rat B cell differentiation in vivo by the administration of an anti-μ monoclonal antibody. J Immunol. 156:1996;108-118.
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(1996)
J Immunol
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Soares, M.1
Havaux, X.2
Nisol, F.3
Baxin, H.4
Latinne, D.5
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32
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0029758113
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Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
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of special interest. The PBSF/SDF-1 chemokine, which is constitutively expressed by bone-marrow-derived stromal cells and induces proliferation of B cell progenitors, was ablated by gene-targeting. The number of pro-β cells and pre-B cells was decreased in the liver and bone marrow of the mutant embryonic mice, indicating that PBSF/SDF-1 is essential for B lymphopoiesis and probably acts earlier than IL-7, which affects expansion of pre-B but not pro-B cells in knockout models. Myeloid progenitors were reduced only in the bone marrow, not the fetal liver, suggesting that the PBSF/SDF-1 chemokine may promote homing of hemopoietic precursors to the embryonic bone marrow.
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of special interest Nagasawa T, Hirota S, Tachibana K, Takakura N, Nishikawa S, Kitamura Y, Yoshida N, Kikutani H, Kishimoto T. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature. 382:1996;635-638 The PBSF/SDF-1 chemokine, which is constitutively expressed by bone-marrow-derived stromal cells and induces proliferation of B cell progenitors, was ablated by gene-targeting. The number of pro-β cells and pre-B cells was decreased in the liver and bone marrow of the mutant embryonic mice, indicating that PBSF/SDF-1 is essential for B lymphopoiesis and probably acts earlier than IL-7, which affects expansion of pre-B but not pro-B cells in knockout models. Myeloid progenitors were reduced only in the bone marrow, not the fetal liver, suggesting that the PBSF/SDF-1 chemokine may promote homing of hemopoietic precursors to the embryonic bone marrow.
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(1996)
Nature
, vol.382
, pp. 635-638
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-
Nagasawa, T.1
Hirota, S.2
Tachibana, K.3
Takakura, N.4
Nishikawa, S.5
Kitamura, Y.6
Yoshida, N.7
Kikutani, H.8
Kishimoto, T.9
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33
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16044370087
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The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
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Oberlin E, Amara A, Bachelerie F, Bessia C, Virelizier J-L, Arenzana-Seisdedos F, Schwartz O, Heare J-M, Clark-Lewis I, Legler DF, et al. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature. 382:1996;833-835.
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(1996)
Nature
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Oberlin, E.1
Amara, A.2
Bachelerie, F.3
Bessia, C.4
Virelizier, J.-L.5
Arenzana-Seisdedos, F.6
Schwartz, O.7
Heare, J.-M.8
Clark-Lewis, I.9
Legler, D.F.10
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34
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0029775576
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The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
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