Defective B Cell Development in Snell Dwarf (dw/dw) Mice Can Be Corrected by Thyroxine Treatment

Journal of Immunology

Volumn 157, Issue 8, 1996, Pages 3334-3340

  Montecino Rodriguez, Encarnacion ^a   Clark, Ross ^b   Johnson, Anne ^a   Collins, Linda ^a   Dorshkind, Kenneth ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOHYPOPHYSIS HORMONE; GROWTH HORMONE; SOMATOMEDIN C; THYROXINE;

ANIMAL; ARTICLE; B LYMPHOCYTE; BAGG ALBINO MOUSE; BONE MARROW; BONE MARROW TRANSPLANTATION; DRUG EFFECT; DWARFISM; GENETICS; HEMATOPOIESIS; IMMUNOLOGY; MOUSE; MOUSE MUTANT; PATHOLOGY;

ANIMALS; B-LYMPHOCYTES; BONE MARROW; BONE MARROW TRANSPLANTATION; DWARFISM; GROWTH HORMONE; HEMATOPOIESIS; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, INBRED BALB C; MICE, MUTANT STRAINS; MICE, SCID; PITUITARY HORMONES, ANTERIOR; THYROXINE;

EID: 0030587892     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Slabaugh M. B., M. E. Lieberman, J. J. Rutledge, and J. Gorski. 1981. Growth hormone and prolactin synthesis in normal and homozygous Snell and Ames dwarf mice. Endocrinology 109:1040.
2. Duquesnoy R. J., and G. M. Pedersen. 1981. Immunologic and hematologic deficiencies of the hypopituitary dwarf mouse. In Immunologic Defects in Laboratory Animals, Vol. 1. M. E. Gershwin and B. Merchant, eds. Plenum Press, New York, p. 309.
3. Li, S., E. B. Crenshaw III, E. J. Rawson, D. M. Simmons, L. W. Swanson, and M. G. Rosenfeld. 1990. Dwarf locus mutants lacking three pituitary cell types result from mutations in the pou-domain gene pit-1. Nature 347:528.
4. van Buul-Offers, S. C., R. J. Bloemen, M. G. Reignen-Gresnigt, H. A. van Leiden, C. M. Hoogerbrugge, and J. L. Van den Brande. Insulin-like growth factors-I and -II and their binding proteins during postnatal development of dwarf Snell mice before and during growth hormone and thyroxine therapy. J. Endocrinol 143:191.
5. Phillips, J. A., W. G. Beamer, and A. Bartke. 1982. Analysis of growth hormone genes in mice with genetic defects of growth hormone expression. J. Endocrinol. 92:405.
6. Fabris, N., W. Pierpaoli, and E. Sorkin. 1971. Hormones and the immunolgical capacity. III. The immunodeficiency disease of the hypopituitary Snell-Bagg dwarf mouse. Clin. Exp. Immunol. 9:209.
7. Fabris, N., W. Pierpaoli, and E. Sorkin. 1971. Hormones and the immunological capacity. IV. Restorative effects of developmental hormones or of lymphocytes on the immunodeficiency syndrome of the dwarf mouse. Clin. Exp. Immunol. 9:227.
8. Murphy, W. J., S. K. Durum, and D. L. Longo. 1993. Differential effects of growth hormone and prolactin on murine T cell development and function. J. Exp. Med 178:231.
9. Murphy, W. J., S. K. Durum, and D. L. Longo. 1992. Role of neuroendocrine hormones in murine T cell development. Growth hormone exerts thymopoietic effects in vivo. J. Immunol. 149:3851.
10. Gala, R. R. 1991. Prolactin and growth hormone in the regulation of the immune system. Proc. Soc. Exp. Biol. Med. 198:513.
11. Murphy, W. J., S. K. Durum, M. R. Anver, and D. L. Longo. 1992. Immunologic and hematologic effects of neuroendocrine hormones: studies on Dw/J Dwarf Mice. J. Immunol. 148:3799.
12. Baroni, C. D., N. Fabris, and G. Bertoli. 1969. Effects of hormones on development and function of lymphoid tissues: synergistic action of thyroxin and somatotropic hormone in pituitary dwarf mice. Immunology 17:303.
13. Dorshkind, K., G. M. Keller, R. A. Phillips, R. G Miller, G. C. Bosma, M. O'Toole, and M. J. Bosma. 1984. Functional status of cells from lymphoid and myeloid tissues in mice with severe combined immunodeficiency disease. J. Immunol 132:1804.
14. Cross, R. J., J. S. Bryson, and T. L. Roszman. 1992. Immunologic disparity in the hypopituitary dwarf mouse. J. Immunol. 148:1347.
15. Duquesnoy, R. J., and R. A. Good. 1970. Prevention of immunologic deficiency in pituitary dwarf mice by prolonged nursing. J. Immunol. 104:1553.
16. Hardy, R. R., C. E. Carmack, S. A. Shinton, J. D. Kemp, and K. Hayakawa. 1991. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173:1213.
17. Collins, L. S., and K. Dorshkind. 1987. A stromal cell line from myeloid long-term bone marrow cultures can support myelopoiesis and B lymphopoiesis. J. Immunol. 138:1082.
18. Geffner, M. E., N. Bersch, B. M. Lippe, R. G. Rosenfeld, R. L. Hintz, and D. W. Golde. 1990. Growth hormone mediates the growth of T-lymphoblast cell lines via locally generated insulin-like growth factor-1. J. Clin. Endocrinol. Metab. 71:464.
19. Clemmons, D. R., L. E. Underwood, and J. J. Van Wyk. 1981. Hormonal control of immunoreactive somatomedin production by cultured human fibroblasts. J. Clin. Invest. 67:10.
20. Landreth, K. S., R. Narayanan, and K. Dorshkind. 1992. Insulin-like growth factor-1 regulates pro-B cell differentiation. Blood 80:1207.
21. Gibson, L. F., D. Piktel, and K. S. Landreth. 1993. Insulin-like growth factor-1 potentiates expansion of interleukin-7-dependent pro-B cells. Blood 82:3005.
22. Jardieu, P., R. Clark, D. Mortensen, and K. Dorshkind. 1994. In vivo administration of insulin-like growth factor-1 stimulates primary B lymphopoiesis and enhances lymphocyte recovery after bone marrow transplantation. J. Immunol. 152:4320.
23. Clark, R., J. Strasser, S. McCabe, K. Robbins, and P. Jardieu. 1993. Insulin-like growth factor-1 stimulation of lymphopoiesis. J. Clin. Invest. 92:540.
24. Gala R. R. 1995. Influence of thyroxine and thyroxine with growth hormone and prolactin on splenocyte subsets and on the expression of interleukin-2 and prolactin receptors on splenocyte subsets of Snell dwarf mice. Proc. Soc. Exp. Biol. Med. 210:117.
25. Hirayama, F., S. D. Lyman, S. C. Clark, and M. Ogawa. 1995. The flt3 ligand supports proliferation of lymphohematopoietic progenitors and early B-lymphoid progenitors. Blood 85:2844.
26. Jost, A. 1969. The extent of foetal endocrine autonomy. In Foetal Autonomy: Ciba Foundation Symposium. G. E. W. Wolstenholme and M. O'Connor, eds. Churchill, London, p. 79.
27. Morreale de Escobar, G., M. J. Obregon, C. Ruiz de Ona, F. Escobar del Rey. 1989. Comparison of maternal to fetal transfer of 3,5,3́-triiodothyronine versus thyroxine in rats as assessed from 3,5,3́-triiodothryonine levels in fetal tissues. Acta Endocrinol. 120:20.
28. Dumont, F., F. Robert, and P. Bischoff. 1979. T and B lymphocytes in pituitary dwarf Snell-Bagg mice. Immunology 38:23.
29. Guyton, A. C. 1971. Medical Physiology, 4th Ed. W. B. Saunders Co., Philadelphia, p. 908.
30. Gala, R. R. 1995 The influence of thyroxine, growth hormone, and prolactin alone and in combination on the production of prolactin-like activity by splenocytes from snell dwarf mice. Life Sci. 57:113.
31. Pierpaoli, W., C. Baroni, N. Fabris, and E. Sorkin. 1969. Hormones and immunological capacity. II. Reconstitution of antibody production in hormonally deficient mice by somatotropic hormone, thyrotropic hormone, and thyroxine. Immunology 16:217.
32. Fabris, N., M. Muzzioli, and E. Mocchegiani. 1982. Recovery of age-dependent immunological deterioration in BALB/c mice by short-term treatement with L-thyroxine. Mech. Ageing Dev. 18:237.
33. Chen, Y. 1980. Effect of thyroxine on the immune response of mice in vivo and in vitro. Immunol. Commun. 9:269.
34. Dorshkind, K. 1991. In vivo administration of recombinant granulocyte-macrophage colony-stimulating factor results in a reversible inhibition of primary B lymphopoiesis. J. Immunol. 146:4204.
35. Park, Y. H., and D. G. Osmond. 1989. Post-irradiation regeneration of early B-lymphocyte precursor cells in mouse bone marrow. Immunology 66:343.
36. Kocher, T. 1908. Blutuntersuchungen bei morbus basedowii mit beitragen zur fruhdiagnose und theorie der krankheit. Arch. Klin. Chir. 87:131.
37. Ultmann, J. E., G. A. Hyman, and B. Calder. 1963. The occurrence of lymphoma in patients with long-standing hyperthroidism. Blood 21:282.
38. Hsu, C. C. S., Y. Chen, and R. Patterson. 1976. Peripheral blood B-lymphocyte abnormalities associtaed with hyperthyroidism of Grave's disease. Clin. Exp. Immunol. 26:431.
39. Fabris, N. 1973. Immunodepression in thyroid-deprived animals. Clin. Exp. Immunol. 15:601.
40. Evans R. M., N. C. Birnberg, and M. G. Rosenfeld. 1982. Glucocorticoid and thyroid hormones transcriptionally regulate growth hormone gene expression. Proc. Natl. Acad Sci. USA 79:7659.
41. Chernausek, S. D., L. E. Underwood, and J. J. Van Wyk. 1982. Influcence of hypothyroidism on growth hormone binding by rat liver. Endocrinology 111: 1534.
42. Hooghe-Peters, E. L., and R. Hooghe. 1995. The B Cell Lineage. In Growth Hormone, Prolactin, and IGF-1 as Lymphohemopoietic Cytokines. R. G. Landes Company, Austin, TX, p. 172.
43. Kincade P. W., K. Medina, and G. Smithson. 1994. Sex hormones as negative regulators of lymphopoiesis. Immunol. Rev. 137:119.