Kinetic properties of saquinavir-resistant mutants of human immunodeficiency virus type 1 protease and their implications in drug resistance in vivo

Biochemistry

Volumn 36, Issue 40, 1997, Pages 12364-12370

  Ermolieff, Jacques ^a   Lin, Xinli ^a   Tang, Jordan ^a,b  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NELFINAVIR; RITONAVIR; SAQUINAVIR;

ARTICLE; CATALYSIS; CELL MATURATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; GENE MUTATION; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INHIBITION KINETICS; LIFE CYCLE; NONHUMAN; PRIORITY JOURNAL; TISSUE CULTURE; VIRUS MUTANT;

DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MICROBIAL; GENOTYPE; HIV PROTEASE; HIV PROTEASE INHIBITORS; HUMANS; KINETICS; MUTAGENESIS, SITE-DIRECTED; PROTEIN PROCESSING, POST-TRANSLATIONAL; SAQUINAVIR; SUBSTRATE SPECIFICITY; VIRION;

EID: 0030870159     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi971072e     Document Type: Article

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