-
1
-
-
0003473940
-
-
New York, NY: Ballantine Books
-
Hayflick L. How and Why We Age. New York, NY: Ballantine Books; 1994:313.
-
(1994)
How and Why We Age
, pp. 313
-
-
Hayflick, L.1
-
3
-
-
0030016821
-
Longevity, genes, and aging
-
Jazwinski SM. Longevity, genes, and aging. Science. 1996;273:54-59.
-
(1996)
Science
, vol.273
, pp. 54-59
-
-
Jazwinski, S.M.1
-
4
-
-
26144438755
-
Jeanne Calment, born 21 February 1875 in Arles, died 4 August 1997 in Paris, France: World's oldest woman dies at 122
-
August 5
-
Jeanne Calment, born 21 February 1875 in Arles, died 4 August 1997 in Paris, France: world's oldest woman dies at 122. Baltimore Sun. August 5, 1997:B5.
-
(1997)
Baltimore Sun
-
-
-
5
-
-
1842313770
-
-
Bethesda, Md: National Institute on Aging, National Institutes of Health
-
National Institute on Aging, National Institutes of Health. In Search of the Secrets of Aging. Bethesda, Md: National Institute on Aging, National Institutes of Health; 1997.
-
(1997)
Search of the Secrets of Aging
-
-
-
6
-
-
0004260866
-
-
New York, NY: Oxford University Press
-
Smith DWE. Human Longevity. New York, NY: Oxford University Press; 1993.
-
(1993)
Human Longevity
-
-
Smith, D.W.E.1
-
8
-
-
0029776793
-
Determination of life-span in Caenorhabditis elegans by four clock genes
-
Lakowski B, Hekimi S. Determination of life-span in Caenorhabditis elegans by four clock genes. Science. 1996;272:1010-1013.
-
(1996)
Science
, vol.272
, pp. 1010-1013
-
-
Lakowski, B.1
Hekimi, S.2
-
9
-
-
0031030678
-
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1
-
Ewbank JJ, Barnes TM, Lakowski B, Lussier M, Bussey H, Hekimi S. Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1. Science. 1997;275:980-983.
-
(1997)
Science
, vol.275
, pp. 980-983
-
-
Ewbank, J.J.1
Barnes, T.M.2
Lakowski, B.3
Lussier, M.4
Bussey, H.5
Hekimi, S.6
-
10
-
-
0028930267
-
Genes that regulate both development and longevity in Caenorhabditis elegans
-
Larsen PL, Albert PS, Riddle DL. Genes that regulate both development and longevity in Caenorhabditis elegans. Genetics. 1995;139:1567-1583.
-
(1995)
Genetics
, vol.139
, pp. 1567-1583
-
-
Larsen, P.L.1
Albert, P.S.2
Riddle, D.L.3
-
12
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science. 1996;273:59-63.
-
(1996)
Science
, vol.273
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
13
-
-
0031545017
-
Beyond the rodent model: Calorie restriction in rhesus monkeys
-
Lane MA, Ingram DK, Roth GS. Beyond the rodent model: calorie restriction in rhesus monkeys. Age. 1997;20:45-56.
-
(1997)
Age
, vol.20
, pp. 45-56
-
-
Lane, M.A.1
Ingram, D.K.2
Roth, G.S.3
-
14
-
-
0015319592
-
The biologic clock: The mitochondria?
-
Harman D. The biologic clock: the mitochondria? J Am Geriatr Soc. 1972;20:145-147.
-
(1972)
J Am Geriatr Soc.
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
15
-
-
0028220114
-
Extension of life-span by overexpression of super oxide dismutase and catalase in Drosophila melanogaster
-
Orr WC, Sojal RJ. Extension of life-span by overexpression of super oxide dismutase and catalase in Drosophila melanogaster. Science. 1994;263: 1128-1138.
-
(1994)
Science
, vol.263
, pp. 1128-1138
-
-
Orr, W.C.1
Sojal, R.J.2
-
16
-
-
0030297546
-
Telomeres and telomerase: A simple picture becomes complex
-
Lundblad V, Wright WE. Telomeres and telomerase: a simple picture becomes complex. Cell. 1996;87:369-375.
-
(1996)
Cell
, vol.87
, pp. 369-375
-
-
Lundblad, V.1
Wright, W.E.2
-
17
-
-
0029973653
-
Regulation of telomerase activity in immortal cell lines
-
Holt SE, Wright WE, Shay JW. Regulation of telomerase activity in immortal cell lines. Mol Cell Biol. 1996;16:2932-2939.
-
(1996)
Mol Cell Biol.
, vol.16
, pp. 2932-2939
-
-
Holt, S.E.1
Wright, W.E.2
Shay, J.W.3
-
18
-
-
77049308856
-
Aging: A theory based on free radical and radiation biology
-
Harman D. Aging: a theory based on free radical and radiation biology. J Gerontol. 1956;11:298-300.
-
(1956)
J Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
19
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science. 1996;273:59-63.
-
(1996)
Science
, vol.273
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
20
-
-
0004205141
-
-
New York, NY: William Morrow & Co;
-
Fossel M. Reversing Human Aging. New York, NY: William Morrow & Co; 1996.
-
(1996)
Reversing Human Aging
-
-
Fossel, M.1
-
21
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, Lee X, Basile G, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A. 1995;92:9363-9367.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
-
22
-
-
0030038104
-
Replicative senescence: Implications for in vivo aging and tumor suppression
-
Smith JR, Pereira-Smith OM. Replicative senescence: implications for in vivo aging and tumor suppression. Science. 1996;273:63-67.
-
(1996)
Science
, vol.273
, pp. 63-67
-
-
Smith, J.R.1
Pereira-Smith, O.M.2
-
23
-
-
0030581150
-
Do changes in chromosomes cause aging?
-
Guarente L. Do changes in chromosomes cause aging? Cell. 1996;86:9-12.
-
(1996)
Cell
, vol.86
, pp. 9-12
-
-
Guarente, L.1
-
24
-
-
0030025660
-
Replicative senescence: An old live's tale
-
Campisi J. Replicative senescence: an old live's tale. Cell. 1996;84:497-500.
-
(1996)
Cell
, vol.84
, pp. 497-500
-
-
Campisi, J.1
-
25
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
Yu CE, Oshima J, Fu YH, et al. Positional cloning of the Werner's syndrome gene. Science. 1996; 272:258-262.
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.E.1
Oshima, J.2
Fu, Y.H.3
-
26
-
-
0026460896
-
Telomere length predicts replicative capacity of human fibroblasts
-
Allsopp RC, Vaziri H, Patterson C, et al. Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci U S A. 1992;89: 10114-10118.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
-
27
-
-
0029808588
-
No detectable mutations at Werner helicase locus in progeria
-
Oshima J, Brown WT, Martin GM. No detectable mutations at Werner helicase locus in progeria. Lancet. 1996;348:1106.
-
(1996)
Lancet
, vol.348
, pp. 1106
-
-
Oshima, J.1
Brown, W.T.2
Martin, G.M.3
-
28
-
-
0031044215
-
Viable offspring derived from fetal and adult mammalian cells
-
Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KHS. Viable offspring derived from fetal and adult mammalian cells. Nature. 1997;385:810-813.
-
(1997)
Nature
, vol.385
, pp. 810-813
-
-
Wilmut, I.1
Schnieke, A.E.2
McWhir, J.3
Kind, A.J.4
Campbell, K.H.S.5
-
29
-
-
0031059342
-
An udder way of making lambs
-
Stewart C. An udder way of making lambs. Nature. 1997;385:769-771.
-
(1997)
Nature
, vol.385
, pp. 769-771
-
-
Stewart, C.1
-
30
-
-
0018832935
-
Protein synthetic errors do not increase during aging of cultured human fibroblasts
-
Harley CB, Pollard JW, Chamberlain JW, Stanner CP, Goldstein S. Protein synthetic errors do not increase during aging of cultured human fibroblasts. Proc Natl Acad Sci U S A. 1980;77:1885-1889.
-
(1980)
Proc Natl Acad Sci U S A
, vol.77
, pp. 1885-1889
-
-
Harley, C.B.1
Pollard, J.W.2
Chamberlain, J.W.3
Stanner, C.P.4
Goldstein, S.5
-
31
-
-
0025279931
-
Telomeres shorten during aging of human fibroblasts
-
Harley CB, Futcher AB, Greider CW. Telomeres shorten during aging of human fibroblasts. Nature. 1990;345:458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
32
-
-
0030581150
-
Do changes in chromosomes cause aging?
-
Guarante L. Do changes in chromosomes cause aging? Cell. 1996;86:9-12.
-
(1996)
Cell
, vol.86
, pp. 9-12
-
-
Guarante, L.1
-
34
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PLC. Specific association of human telomerase activity with immortal cells and cancer. Science. 1994;266:2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.C.6
-
35
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay JW, Bacchetti S. A survey of telomerase activity in human cancer. Eur J Cancer. 1997;33: 787-791.
-
(1997)
Eur J Cancer
, vol.33
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
36
-
-
0030819894
-
Telomerase catalytic subunit homologs from fission yeast and human
-
Nakamura TM, Morin GB, Chapman KB, et al. Telomerase catalytic subunit homologs from fission yeast and human. Science. 1997;277:955-959.
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
-
37
-
-
0030745448
-
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
-
Meyerson M, Counter C, Eaton EN, et al. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell. 1997;90:785-795.
-
(1997)
Cell
, vol.90
, pp. 785-795
-
-
Meyerson, M.1
Counter, C.2
Eaton, E.N.3
-
38
-
-
0029854071
-
Targets for cancer therapy in the cell cycle pathway
-
Rao RN. Targets for cancer therapy in the cell cycle pathway. Curr Opin Oncol. 1996;8:516-524.
-
(1996)
Curr Opin Oncol.
, vol.8
, pp. 516-524
-
-
Rao, R.N.1
-
39
-
-
0029849620
-
Cancer cell cycles
-
Sherr CJ. Cancer cell cycles. Science. 1996;274: 1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
40
-
-
0031043998
-
Telomerase in the early detection of cancer
-
Shay JW, Gazdar AF. Telomerase in the early detection of cancer. J Clin Pathol. 1997;50:106-109.
-
(1997)
J Clin Pathol.
, vol.50
, pp. 106-109
-
-
Shay, J.W.1
Gazdar, A.F.2
-
41
-
-
0029096515
-
The RNA component of human telomerase
-
Feng J, Funk WD, Wang SS, et al. The RNA component of human telomerase. Science. 1995;269: 1236-1241.
-
(1995)
Science
, vol.269
, pp. 1236-1241
-
-
Feng, J.1
Funk, W.D.2
Wang, S.S.3
-
42
-
-
1842309963
-
Molecular and genetic strategies for treatment of age-related diseases
-
July 14-15, Seattle, Wash.
-
Jazwinski SM, Martin GM, Schellenberg GD, et al. Molecular and genetic strategies for treatment of age-related diseases. Presented at the National Managed Health Care Congress: Bio/technology Conferences; July 14-15, 1997; Seattle, Wash.
-
(1997)
National Managed Health Care Congress: Bio/technology Conferences
-
-
Jazwinski, S.M.1
Martin, G.M.2
Schellenberg, G.D.3
-
43
-
-
1842305147
-
Scanning the research horizon
-
Editorial box
-
Scanning the research horizon. Science. 1996; 274:1989. Editorial box.
-
(1996)
Science
, vol.274
, pp. 1989
-
-
-
44
-
-
0030004489
-
Experimental elongation of telomeres extends the life span of immortal x normal cell hybrids
-
Wright WE, Brasiskyte D, Piatyszek MA, Shay JE. Experimental elongation of telomeres extends the life span of immortal x normal cell hybrids. EMBO J. 1996;15:1734-1741.
-
(1996)
EMBO J.
, vol.15
, pp. 1734-1741
-
-
Wright, W.E.1
Brasiskyte, D.2
Piatyszek, M.A.3
Shay, J.E.4
-
45
-
-
0028568315
-
Cell cycle control and cancer
-
Hartwell LH, Kastan MB. Cell cycle control and cancer. Science. 1994;266:1821-1828.
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
46
-
-
0029973389
-
Cell-cycle control and its watchman
-
Jacks T, Weinberg RA. Cell-cycle control and its watchman. Nature. 1996;381:643-644.
-
(1996)
Nature
, vol.381
, pp. 643-644
-
-
Jacks, T.1
Weinberg, R.A.2
-
47
-
-
0030473646
-
Aging global population: A call for papers
-
Winker MA, Glass RM. Aging global population: a call for papers. JAMA. 1996;276:1758.
-
(1996)
JAMA
, vol.276
, pp. 1758
-
-
Winker, M.A.1
Glass, R.M.2
-
48
-
-
0029012793
-
Longevity requires policy revolution
-
Marwick C. Longevity requires policy revolution. JAMA. 1995;273:1319-1321.
-
(1995)
JAMA
, vol.273
, pp. 1319-1321
-
-
Marwick, C.1
-
49
-
-
0028810339
-
Survival after the age of 80 in the United States, Sweden, France, England, and Japan
-
Manton KG, James VW. Survival after the age of 80 in the United States, Sweden, France, England, and Japan. N Engl J Med. 1995;333:1232-1235.
-
(1995)
N Engl J Med.
, vol.333
, pp. 1232-1235
-
-
Manton, K.G.1
James, V.W.2
-
51
-
-
0028946554
-
Longevity and Medicare expenditures
-
Lubitz J, Beebe J, Baker C. Longevity and Medicare expenditures. N Engl J Med. 1995;332: 999-1003.
-
(1995)
N Engl J Med.
, vol.332
, pp. 999-1003
-
-
Lubitz, J.1
Beebe, J.2
Baker, C.3
-
52
-
-
0025327309
-
The aging of America: Impact on health care costs
-
Schneider EL, Guralnik JM. The aging of America: impact on health care costs. JAMA. 1990; 263:2335-2340.
-
(1990)
JAMA
, vol.263
, pp. 2335-2340
-
-
Schneider, E.L.1
Guralnik, J.M.2
-
53
-
-
0030909364
-
Chronic disability trends in the elderly United States populations: 1982-1994
-
Manton KG, Corder L, Stallard E. Chronic disability trends in the elderly United States populations: 1982-1994. Proc Natl Acad Sci U S A. 1997; 94:2593-2598.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 2593-2598
-
-
Manton, K.G.1
Corder, L.2
Stallard, E.3
-
55
-
-
0025126569
-
The social impact of AIDS in sub-Saharan Africa
-
Van De Walle E. The social impact of AIDS in sub-Saharan Africa. Milbank Q. 1990;68(1):10-32.
-
(1990)
Milbank Q.
, vol.68
, Issue.1
, pp. 10-32
-
-
Van De Walle, E.1
-
57
-
-
0027375747
-
Forecasts of active life expectancy: Policy and fiscal implications
-
Manton KG, Stallard E, Liu K. Forecasts of active life expectancy: policy and fiscal implications. J Gerontol. 1993;48:11-26.
-
(1993)
J Gerontol.
, vol.48
, pp. 11-26
-
-
Manton, K.G.1
Stallard, E.2
Liu, K.3
-
58
-
-
0015040543
-
A single index of mortality and morbidity
-
Sullivan DF. A single index of mortality and morbidity. HSMHA Health Rep. 1971;86:347-354.
-
(1971)
HSMHA Health Rep.
, vol.86
, pp. 347-354
-
-
Sullivan, D.F.1
-
59
-
-
0031062273
-
Death and taxes: Longer life, consumption, and social security
-
Lee R, Tuljapurkar S. Death and taxes: longer life, consumption, and social security. Demography. 1997;34(1):67-81.
-
(1997)
Demography
, vol.34
, Issue.1
, pp. 67-81
-
-
Lee, R.1
Tuljapurkar, S.2
-
60
-
-
0031062279
-
Retirement against the demographic trend: More older people living longer, working less, and saving less
-
Wise DA. Retirement against the demographic trend: more older people living longer, working less, and saving less. Demography. 1997;34(1):83-95.
-
(1997)
Demography
, vol.34
, Issue.1
, pp. 83-95
-
-
Wise, D.A.1
-
62
-
-
0026741156
-
Health care for the elderly in Japan: Medicine and welfare in an aging society facing a crisis in long term care
-
Okamoto Y. Health care for the elderly in Japan: medicine and welfare in an aging society facing a crisis in long term care. BMJ. 1992;305:403-405.
-
(1992)
BMJ
, vol.305
, pp. 403-405
-
-
Okamoto, Y.1
|