Identification of 3-hydroxypalmitic acid methyl ester as a novel autoregulator controlling virulence in Ralstonia solanacearum

Molecular Microbiology

Volumn 26, Issue 2, 1997, Pages 251-259

  Flavier, Albert B ^a,c   Clough, Steven J ^a,d   Schell, Mark A ^a,b   Denny, Timothy P ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID DERIVATIVE; PALMITIC ACID DERIVATIVE; VIRULENCE FACTOR;

ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; DISTILLATION; GAS CHROMATOGRAPHY; GENE EXPRESSION REGULATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS); RALSTONIA SOLANACEARUM;

EID: 0030775686     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1997.5661945.x     Document Type: Article

References (48)

1. Boulton, C.A. (1989) Extracellular microbial lipids. In Microbial Lipids, Vol. 2. Ratledge, C., and Wilkinson, S.G. (eds). London: Academic Press, pp. 669-694.
2. Brumbley, S.M., and Denny, T.P. (1990) Cloning of phcA from wild-type Pseudomonas solanacearum, a gene that when mutated alters expression of multiple traits that contribute to virulence. J Bacteriol 172: 5677-5685.
3. Brumbley, S.M., Carney, B.F., and Denny, T.P. (1993) Phenotype conversion in Pseudomonas solanacearum due to spontaneous inactivation of PhcA, a putative LysR transcriptional activator. J Bacteriol 175: 5477-5487.
4. Clewell, D.B. (1993) Bacterial sex pheromone-induced plasmid transfer. Cell 73: 9-12.
5. Clough, S.J. (1991) Regulation of virulence in Pseudomonas solanacearum by an endogenous volatile compound. MS thesis, University of Georgia, Athens.
6. Clough, S.J., Schell, M.A., and Denny, T.P. (1994) Evidence for involvement of a volatile extracellular factor in Pseudomonas solanacearum virulence gene expression. Mol Plant-Microbe Interact 7: 621-630.
7. Clough, S.J., Flavier, A.B., Schell, M.A., and Denny, T.P. (1997a) Differential expression of virulence genes and motility in Ralstonia (Pseudomonas) solanacearum during exponential growth. Appl Environ Microbiol 63: 884-850.
8. Clough, S.J., Lee, K.-E., Schell, M.A., and Denny, T.P. (1997b) A two-component system in Ralstonia (Pseudomonas) solanacearum modulates production of PhcA-regulated virulence factors in response to 3-hydroxypalmitic acid methyl ester. J Bacteriol 179: 3639-3648.
9. Denny, T.P., and Baek, S.R. (1991) Genetic evidence that extracellular polysaccharide is a virulence factor of Pseudomonas solanacearum. Mol Plant-Microbe Interact 4: 198-206.
10. Denny, T.P., Makini, F.W., and Brumbley, S.M. (1988) Characterization of Pseudomonas solanacearum Tn5 mutants deficient in extracellular polysaccharide. Mol Plant-Microbe Interact 1: 215-223.
11. Djordjevic, S., and Stock, A.M. (1997) Crystal structure of the chemotaxis receptor methyltransferase CheR suggests a conserved structural motif for binding S-adenosylmethionine. Structure 5: 545-558.
12. Downard, J., and Toal, D. (1995) Branched-chain fatty acids: The case for a novel form of cell-cell signalling during Myxococcus xanthus development. Mol Microbiol 16: 171-175.
13. Dworkin, M. (1996) Recent advances in the social and developmental biology of the myxobacteria. Microbiol Rev 60: 70-102.
14. Flavier, A.B. (1997) Endogenous Signal Molecules and Gene Regulation in Ralstonia solanacearum. PhD dissertation, University of Georgia, Athens.
15. Fu, Z., Hu, Y., Konishi, K., Takata, Y., Ogawa, H., Gomi, T., Fujioka, M., and Takusagawa, F. (1996) Crystal structure of glycine N-methyltransferase from rat liver. Biochemistry 35: 11985-11993.
16. Fuqua, C., Winans, S.C., and Greenberg, E.P. (1996) Census and consensus in bacterial ecosystems: the LuxR-LuxI family of quorum-sensing transcriptional regulators. Annu Rev Microbiol 50: 727-751.
17. Hamahata, A., Takata, Y., Gomi, T., and Fujioka, M. (1996) Probing the S-adenosylmethionine-binding site of rat guanidinoacetate methyltransferase. Biochem J 141-145.
18. Horinouchi, S., and Beppu, T. (1994) A-factor as a microbial hormone that controls cellular differentiation and secondary metabolism in Streptomyces griseus. Mol Microbiol 12: 859-864.
19. Janse, J.D. (1991) Infra- and intraspecific classification of Pseudomonas solanacearum strains, using whole cell fatty acid analysis. System Appl Microbiol 14: 335-345.
20. Ji, G., Beavis, R.C., and Novick, R.P. (1995) Cell-density control of staphylococcal virulence mediated by an octapeptide pheromone. Proc Natl Acad Sci USA 92: 12055-12059.
21. Kagan, R.M., and Clarke, S. (1994) Widespread occurrence of three sequence motifs in diverse S-adenosylmethionine-dependent methyltransferases suggests a common structure for these enzymes. Arch Biochem Biophys 310: 417-427.
22. Kaiser, D. (1996) Bacteria also vote. Science 272: 1598.
23. Kaplan, H.B., and Greenberg, E.P. (1985) Diffusion of autoinducer is involved in regulation of the Vibrio fischeri luminescence system. J Bacteriol 163: 1210-1214.
24. Kaplan, H.B., and Plamann, L. (1996) A Myxococcus xanthus cell density-sensing system required for multicellular development. FEMS Lett 139: 89-95.
25. Latifi, A., Foglino, M., Tanaka, K., Williams, P., and Lazdunski, A. (1996) A hierarchical quorum-sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationaryphase sigma factor RpoS. Mol Microbiol 21: 1137-1146.
26. Magnuson, K., Jackowski, S., Rock, C.O., and Cronan, Jr, J.E. (1993) Regulation of fatty acid biosynthesis in Escherichia coli. Microbiol Rev 57: 522-542.
27. Meighen, E.A. (1994) Genetics of bacterial bioluminescence. Annu Rev Genet 28: 117-139.
28. Moré, M.I., Finger, L.D., Stryker, J.L., Fuqua, C., Eberhard, A., and Winans, S.C. (1996) Enzymatic synthesis of a quorum-sensing autoinducer through use of defined substrates. Science 272: 1655-1658.
29. Parkinson, J.S., and Kofoid, E.C. (1992) Communication modules in bacterial signaling proteins. Annu Rev Genet 26: 71-112.
30. Pearson, J.P., Gray, K.M., Passador, L., Tucker, K.D., Eberhard, A., Iglewski, B.H., and Greenberg, E.P. (1994) Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes. Proc Natl Acad Sci USA 91: 197-201.
31. Pesci, E.C., Pearson, J.P., Seed, P.C., and Iglewski, B.H. (1997) Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa. J Bacteriol 179: 3127-3132.
32. Piper, K.R., Beck von Bodman, S., and Farrand, S.K. (1993) Conjugation factor of Agrobacterium tumefaciens regulates Ti-plasmid transfer by autoinduction. Nature 362: 448-450.
33. Prego, M., and Hoch, J.A. (1996) Cell-cell communication regulates the effects of protein aspartate phosphatases on the phosphorelay controlling development in Bacillus subtilis. Proc Natl Acad Sci USA 93: 1549-1553.
34. Rost, B. (1996) PHD: predicting one-dimensional protein structure by profile based neural networks. Methods Enzymol 266: 525-539.
35. Salmond, G.P.C., Bycroft, B.W., Stewart, G.S.A.B., and Williams, P. (1995) The bacterial 'enigma': cracking the code of cell-cell communication. Mol Microbiol 16: 615-624.
36. Schaefer, A.L., Val, D.L., Hanzelka, B.L., Cronan, J.E., and Greenberg, E.P. (1996) Generation of cell-to-cell signals in quorum sensing: Acyl homoserine lactone synthase activity of a purified Vibrio fischeri Luxl protein. Proc Natl Acad Sci USA 93: 9505-9509.
37. Schell, M.A. (1996) To be or not to be: how Pseudomonas solanacearum decides whether or not to express virulence genes. Eur J Plant Pathol 102: 459-469.
38. Schluckebier, G., O'Gara, M., Saenger, W., and Cheng, X. (1995) Universal catalytic domain structure of AdoMet-dependent methyltransferases. J Mol Biol 247: 16-20.
39. Schweizer, E. (1989) Biosynthesis of fatty acids and related compounds. In Microbial Lipids, Vol. 2. Ratledge, C., and Wilkinson, S.G. (eds). London: Academic Press, pp. 3-50.
40. Shapiro, J.A. (1995) The significances of bacterial colony patterns. BioEssays 17: 597-607.
41. Solomon, J.M., Lazazzera, B.A., and Grossman, A.D. (1996) Purification and characterization of an extracellular peptide factor that affects two different developmental pathways in Bacillus subtilis. Genes Dev 10: 2014-2024.
42. Stead, D.E. (1992) Grouping of plant-pathogenic and some other Pseudomonas spp. by using cellular fatty acid profiles. Int J Syst Bacteriol 42: 281-295.
43. Stephens, K. (1986) Pheromones among the procaryotes. CRC Crit Rev Microbiol 13: 309-334.
44. Strauch, M.A., de Mendoza, D., and Hoch, J.A. (1992) cis-Unsaturated fatty acids specifically inhibit a signal-transducing protein kinase required for initiation of sporulation in Bacillus subtilis. Mol Microbiol 6: 2909-2917.
45. Ulitzur, S., and Dunlap, P.V. (1995) Regulatory circuitry controlling luminescence autoinduction in Vibrio fischeri. Photochem Photobiol 62: 625-632.
46. Vidgren, J., Svensson, L.A., and Liljas, A. (1994) Crystal structure of catechol O-methyltransferase. Nature 368: 354-358.
47. Wilkinson, S.G. (1988) Gram-negative bacteria. In Microbial Lipids, Vol. 1. Ratledge, C., and Wilkinson, S.G. (eds). London: Academic Press, pp. 299-488.
48. Willcock, D.F., Dryden, D.T.F., and Murray, N.E. (1997) A mutational analysis of the two motifs common to adenine methyltransferases. EMBO J 13: 3902-3908.