Point mutations in human O6-alkylguanine-DNA alkyltransferase prevent the sensitization by O6-benzylguanine to killing by N,N′-Bis(2-chloroethyl)-N-nitrosourea

Cancer Research

Volumn 56, Issue 7, 1996, Pages 1578-1583

  Loktionova, Natalia A ^a   Pegg, Anthony E ^a,b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIAMINO 6 BENZYLOXY 5 NITROSOPYRIMIDINE; 2,4 DIAMINOPYRIMIDINE DERIVATIVE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE INHIBITOR; 6 O BENZYLGUANINE; ALANINE; BENZYL DERIVATIVE; CARMUSTINE; GLYCINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CANCER CELL DESTRUCTION; CANCER RESISTANCE; CHO CELL; CONTROLLED STUDY; CYTOTOXICITY; DNA REPAIR; DOSE RESPONSE; ENZYME ACTIVITY; GENE INSERTION; GENE THERAPY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CARMUSTINE; CELL SURVIVAL; CHO CELLS; CRICETINAE; DRUG RESISTANCE; GUANINE; HUMANS; METHYLTRANSFERASES; MOLECULAR SEQUENCE DATA; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; POINT MUTATION; TRANSFECTION;

EID: 0029997217     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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