Interplay between human papillomaviruses and dendritic cells

Current Topics in Microbiology and Immunology

Volumn 276, Issue , 2003, Pages 215-240

  Offringa, R ^a   De Jong, A ^a   Toes, R E M ^a   Van der Burg, S H ^a   Melief, C J M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CAPSID PROTEIN; FREUND ADJUVANT; GENE PRODUCT; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTERLEUKIN 10; PROSTAGLANDIN E2; RECOMBINANT VACCINE; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; VIRUS VACCINE;

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; CANCER GRADING; CANCER REGRESSION; CELL INTERACTION; CELLULAR IMMUNITY; CROSS REACTION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DRUG DELIVERY SYSTEM; EARLY DIAGNOSIS; HELPER CELL; HUMAN; IMMUNE DEFICIENCY; IMMUNOGENICITY; IMMUNOLOGICAL MEMORY; IMMUNOMODULATION; IMMUNOSURVEILLANCE; INFECTION PREVENTION; INTESTINE LYMPHATIC TISSUE; KERATINOCYTE; LANGERHANS CELL; NATURAL KILLER CELL; NONHUMAN; PRECANCER; PRIORITY JOURNAL; REVIEW; SEROPREVALENCE; SKIN CANCER; TH1 CELL; VACCINATION; VIRUS IMMUNITY; VIRUS INFECTION; VIRUS PARTICLE; VIRUS RECOMBINANT; WART VIRUS;

ADENOVIRIDAE; HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPES; PAPILLOMAVIRUS;

EID: 0013035355     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-662-06508-2_10     Document Type: Review

References (111)

1. Allavena P, Piemonti L, Longoni D, Bernasconi S, Stoppacciaro A, Ruco L. and Mantovani A, IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages. Eur J Immunol 28 359-69. (1998)
2. Alleva D.G, Burger C.J. and Elgert K.D, Tumor-induced regulation of suppressor macrophage nitric oxide and TNF-alpha production. Role of tumor-derived IL-10 TGF-beta and prostaglandin E2. J Immunol 153 1674-86. (1994)
3. al-Saleh W, Giannini S.L, Jacobs N, Moutschen M, Doyen J, Boniver J. and Delvenne P, Correlation of T-helper secretory differentiation and types of antigen-presenting cells in squamous intraepithelial lesions of the uterine cervix. J Pathol 184 283-90. (1998)
4. Beissert S, Hosoi J, Grabbe S, Asahina A. and Granstein R.D, IL-10 inhibits tumor antigen presentation by epidermal antigen-presenting cells. J Immunol 154 1280-6. (1995)
5. Bogdan C, Vodovotz Y. and Nathan C, Macrophage deactivation by interleukin 10. J Exp Med 174 1549-55. (1991)
6. Bonham C.A, Lu L, Banas R.A, Fontes P, Rao A.S, Starzl T.E, Zeevi A. and Thomson A.W, TGF-beta 1 pretreatment impairs the allostimulatory function of human bone marrow-derived antigen-presenting cells for both naive and primed T cells. Transpl Immunol 4 186-91. (1996)
7. Brandtzaeg P, Farstad I.N, and Haraldsen G, Regional specialization in the mucosal immune system: primed cells do not always home along the same track. Immunol Today 20 267-77. (1999)
8. Breitburd F, Salmon J. and Orth G, The rabbit viral skin papillomas and carcinomas: a model for the immunogenetics of HPV-associated carcinogenesis. Clin Dermatol 15 237-47. (1997)
9. Buelens C, Verhasselt V, De Groote D, Thielemans K, Goldman M. and Willems F, Interleukin-10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin-4 and granulocyte/macrophage-colony-stimulating factor. Eur J Immunol 27 756-62. (1997)
10. Campbell D.J. and Butcher E.C. Rapid acquisition of tissue-specific homing phenotypes by CD4(+) T cells activated in cutaneous or mucosal lymphoid tissues. J Exp Med 195 135-41. (2002)
11. Clerici M, Shearer G.M. and Clerici E, Cytokine dysregulation in invasive cervical carcinoma and other human neoplasias: time to consider the TH1/TH2 paradigm. J Natl Cancer Inst 90 261-3. (1998)
12. Comerci J.T, Jr, Runowicz C.D, Flanders K.C, De Victoria C, Fields A.L, Kadish A.S. and Goldberg G.L, Altered expression of transforming growth factor-beta 1 in cervical neoplasia as an early biomarker in carcinogenesis of the uterine cervix. Cancer 77 1107-14. (1996)
13. Czerkinsky C, Anjuere F, McGhee J.R, George-Chandy A, Holmgren J, Kieny M.P, Fujiyashi K, Mestecky J.F, Pierrefite-Carle V, Rask C. and Sun J.B, Mucosal immunity and tolerance: relevance to vaccine development. Immunol Rev 170 197-222. (1999)
14. de Gruijl T.D, Bontkes H.J, van den Muysenberg A.J, van Oostveen J.W, Stukart M.J, Verheijen R.H, van der Vange N, Snijders P.J, Meijer C.J, Walboomers J.M. and Scheper R.J, Differences in cytokine mRNA profiles between premalignant and malignant lesions of the uterine cervix. Eur J Cancer 35 490-7. (1999)
15. de Jong A, van der Burg S.H, Kwappenberg K.M, van der Hulst J.M, Franken K.L, Geluk A, van Meijgaarden K.E, Drijfhout J.W, Kenter G, Vermeij P, Melief C.J. and Offringa R, Frequent detection of human papillomavirus 16 E2-specific T-helper immunity in healthy subjects. Cancer Res 62 472-9. (2002)
16. De Smedt T, Van Mechelen M, De Becker G, Urbain J, Leo O. and Moser M, Effect of interleukin-10 on dendritic cell maturation and function. Eur J Immunol 27 1229-35. (1997)
17. de Waal Malefyt R, Abrams J, Bennett B, Figdor C.G. and de Vries J.E, Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 174 1209-20. (1991)
18. Diehl L, den Boer A.T, Schoenberger S.P, van der Voort E.I, Schumacher T.N, Melief C.J, Offringa R. and Toes R.E, CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy. Nat Med 5 774-9. (1999)
19. Dieu-Nosjean M.C, Massacrier C, Homey B, Vanbervliet B, Pin J.J, Vicari A, Lebecque S, Dezutter-Dambuyant C, Schmitt D, Zlotnik A. and Caux C, Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors. J Exp Med 192 705-18. (2000)
20. Dobbs S.P, Hewett P.W, Johnson I.R, Carmichael J. and Murray J.C, Angiogenesis is associated with vascular endothelial growth factor expression in cervical intraepithelial neoplasia. Br J Cancer 76 1410-5 (1997)
21. D'Orazio T.J. and Niederkorn J.Y, A novel role for TGF-beta and IL-10 in the induction of immune privilege. J Immunol 160 2089-98. (1998)
22. Elson D.A, Riley R.R, Lacey A, Thordarson G, Talamantes F.J. and Arbeit J.M, Sensitivity of the cervical transformation zone to estrogen-induced squamous carcinogenesis. Cancer Res 60 1267-75. (2000)
23. Enk A.H, Angeloni V.L, Udey M.C. and Katz S.I, Inhibition of Langerhans cell antigen-presenting function by IL-10. A role for IL-10 in induction of tolerance. J Immunol 151 2390-8. (1993)
24. Enk A.H, Jonuleit H, Saloga J. and Knop J, Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma. Int J Cancer 73 309-16. (1997)
25. Evander M, Edlund K, Gustafsson A, Jonsson M, Karlsson R, Rylander E. and Wadell G, Human papillomavirus infection is transient in young women: a population-based cohort study. J Infect Dis 171 1026-30. (1995)
26. Evans M, Borysiewicz L.K, Evans A.S, Rowe M, Jones M, Gileadi U, Cerundolo V. and Man S, Antigen processing defects in cervical carcinomas limit the presentation of a CTL epitope from human papillomavirus 16 E6. J Immunol 167 5420-8. (2001)
27. Fiorentino D.F, Zlotnik A, Mosmann T.R, Howard M. and O'Garra A, IL-10 inhibits cytokine production by activated macrophages. J Immunol 147 3815-22. (1991)
28. Frazer I.H, De Kluyver R, Leggatt G.R, Guo H.Y, Dunn L, White O, Harris C, Liem A. and Lambert P, Tolerance or immunity to a tumor antigen expressed in somatic cells can be determined by systemic proinflammatory signals at the time of first antigen exposure. J Immunol 167 6180-7. (2001)
29. Frazer I.H, Thomas R, Zhou J, Leggatt G.R, Dunn L, McMillan N, Tindle R.W, Filgueira L, Manders P, Barnard P. and Sharkey M, Potential strategies utilised by papillomavirus to evade host immunity. Immunol Rev 168 131-42. (1999)
30. Fujimoto J, Sakaguchi H, Hirose R, Ichigo S. and Tamaya T, Expression of vascular endothelial growth factor (VEGF) and its mRNA in uterine cervical cancers. Br J Cancer 80 827-33. (1999)
31. Gabrilovich D, Ishida T, Oyama T, Ran S, Kravtsov V, Nadaf S. and Carbone D.P, Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. Blood 92 4150-66. (1998)
32. Gabrilovich D.I, Chen H.L, Girgis K.R, Cunningham H.T, Meny G.M, Nadaf S, Kavanaugh D. and Carbone D.P, Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med 2 1096-103. (1996)
33. Garrido F, Ruiz-Cabello F, Cabrera T, Perez-Villar J.J, Lopez-Botet M, Duggan-Keen M. and Stern P.L, Implications for immunosurveillance of altered HLA class I phenotypes in human tumours. Immunol Today 18 89-95. (1997)
34. Gerber S, Lane C, Brown D.M, Lord E, DiLorenzo M, Clements J.D, Rybicki E, Williamson A.L. and Rose R.C, Human papillomavirus virus-like particles are efficient oral immunogens when coadministered with Escherichia coli heat-labile enterotoxin mutant R192G or CpG DNA. J Virol 75 4752-60. (2001)
35. Giannini S.L, Al-Saleh W, Piron H, Jacobs N, Doyen J, Boniver J. and Delvenne P, Cytokine expression in squamous intraepithelial lesions of the uterine cervix: implications for the generation of local immunosuppression. Clin Exp Immunol 113 183-9. (1998)
36. Hackstein H, Morelli A.E. and Thomson A.W, Designer dendritic cells for tolerance induction: guided not misguided missiles. Trends Immunol 22 437-42. (2001)
37. Harwood C.A, Surentheran T, McGregor J.M, Spink P.J, Leigh I.M, Breuer J. and Proby C.M, Human papillomavirus infection and non-melanoma skin cancer in immunosuppressed and immunocompetent individuals. J Med Virol 61 289-97. (2000)
38. Havran W.L, Chien Y.H. and Allison J.P, Recognition of self antigens by skin-derived T cells with invariant gamma delta antigen receptors. Science 252 1430-2. (1991)
39. Hayday A, Theodoridis E, Ramsburg E. and Shires J, Intraepithelial lymphocytes: exploring the Third Way in immunology. Nat Immunol 2 997-1003. (2001)
40. Heath W.R. and Carbone F.R, Cross-presentation dendritic cells tolerance and immunity. Annu Rev Immunol 19 47-64 (2001)
41. Ho G.Y, Bierman R, Beardsley L, Chang C.J. and Burk R.D, Natural history of cervicovaginal papillomavirus infection in young women. N Engl J Med 338 423-8. (1998)
42. Hughes R.G, Norval M. and Howie S.E, Expression of major histocompatibility class II antigens by Langerhans' cells in cervical intraepithelial neoplasia. J Clin Pathol 41 253-9. (1988)
43. Ishida T, Oyama T, Carbone D.P. and Gabrilovich D.I, Defective function of Langerhans cells in tumor-bearing animals is the result of defective maturation from hemopoietic progenitors. J Immunol 161 4842-51. (1998)
44. Jakob T, Ring J. and Udey M.C, Multistep navigation of Langerhans/dendritic cells in and out of the skin. J Allergy Clin Immunol 108 688-96. (2001)
45. Jonuleit H, Schmitt E, Steinbrink K. and Enk A.H, Dendritic cells as a tool to induce anergic and regulatory T cells. Trends Immunol 22 394-400. (2001)
46. Kalinski P, Schuitemaker J.H, Hilkens C.M. and Kapsenberg M.L, Prostaglandin E2 induces the final maturation of IL-12-deficient CDla+CD83+ dendritic cells: the levels of IL-12 are determined during the final dendritic cell maturation and are resistant to further modulation. J Immunol 161 2804-9. (1998)
47. King C, Davies J, Mueller R, Lee M.S, Krahl T, Yeung B, O'Connor E. and Sarvetnick N, TGF-betal alters APC preference polarizing islet antigen responses toward a Th2 phenotype. Immunity 8 601-13. (1998)
48. Kondo S, The roles of keratinocyte-derived cytokines in the epidermis and their possible responses to UVA-irradiation. J Investig Dermatol Symp Proc 4 177-83. (1999)
49. Konya J. and Dillner J, Immunity to oncogenic human papillomaviruses. Adv Cancer Res 82 205-38. (2001)
50. Koutsky L, Epidemiology of genital human papillomavirus infection. Am J Med 102 3-8. (1997)
51. Koutsky L.A, Ault K.A, Wheeler C.M, Brown D.R, Barr E, Alvarez EB, Chiacchierini L.M, Jansen K.U, A controlled trial of a human papillomavirus type 16 vaccine. N Engl J Med 347 1645-51. (2002)
52. Lanzavecchia A. and Sallusto F, The instructive role of dendritic cells on T cell responses: lineages plasticity and kinetics. Curr Opin Immunol 13 291-8. (2001)
53. Le Buanec H, D'Anna R, Lachgar A, Zagury J.F, Bernard J, Ittele D, d'Alessio P, Hallez S, Giannouli C, Burny A, Bizzini B, Gallo R.C. and Zagury D, HPV-16 E7 but not E6 oncogenic protein triggers both cellular immunosuppression and angiogenic processes. Biomed Pharmacother 53 424-31. (1999)
54. Liu L, Rich B.E, Inobe J, Chen W. and Weiner H.L, Induction of Th2 cell differentiation in the primary immune response: dendritic cells isolated from adherent cell culture treated with IL-10 prime naive CD4+ T cells to secrete IL-4. Int Immunol 10 1017-26. (1998)
55. Man S. and Fiander A, Immunology of human papillomavirus infection in lower genital tract neoplasia. Best Pract Res Clin Obstet Gynaecol 15 701-14. (2001)
56. Marrack P, Bender J, Hildeman D, Jordan M, Mitchell T, Murakami M, Sakamoto A, Schaefer B.C, Swanson B. and Kappler J, Homeostasis of alpha beta TCR+ T cells. Nat Immunol 1 107-11. (2000)
57. Marx P.A, Compans R.W, Gettie A, Staas J.K, Gilley R.M, Mulligan M.J, Yamshchikov G.V, Chen D. and Eldridge J.H, Protection against vaginal SIV transmission with microencapsulated vaccine. Science 260 1323-7. (1993)
58. Masopust D, Vezys V, Marzo A.L. and Lefrancois L, Preferential localization of effector memory cells in nonlymphoid tissue. Science 291 2413-7. (2001)
59. McArdle J.P. and Muller H.K, Quantitative assessment of Langerhans' cells in human cervical intraepithelial neoplasia and wart virus infection. Am J Obstet Gynecol 154 509-15. (1986)
60. Medema J.P, de Jong J, Peltenburg L.T, Verdegaal E.M, Gorter A, Bres S.A, Franken K.L, Hahne M, Albar J.P, Melief C.J. and Offringa R, Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors. Proc Natl Acad Sci U S A 98 11515-20. (2001)
61. Melief C.J, Toes R.E, Medema J.P, van der Burg S.H, Ossendorp F. and Offringa R, Strategies for immunotherapy of cancer. Adv Immunol 75 235-82 (2000)
62. Menetrier-Caux C, Montmain G, Dieu M.C, Bain C, Favrot M.C, Caux C. and Blay J.Y, Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor. Blood 92 4778-91. (1998)
63. Meuwissen R, Jonkers J. and Berns A, Mouse models for sporadic cancer. Exp Cell Res 264 100-10. (2001a)
64. Meuwissen R, Linn S.C, van der Valk M, Mooi W.J. and Berns A, Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene. Oncogene 20 6551-8. (2001b)
65. van Mierlo G.J, den Boer A.T, Medema J.P, van Der Voort E.I, Fransen M.F, Offringa R, Melief C.J, and Toes R.E. CD40 stimulation leads to effective therapy of CD40-tumors through induction of strong systemic cytotoxic T lymphocyte immunity Proc Natl Acad Sci USA 99 5561-6. (2002)
66. Morales J, Homey B, Vicari A.P, Hudak S, Oldham E, Hedrick J, Orozco R, Copeland N.G, Jenkins N.A, McEvoy L.M. and Zlotnik A, CTACK a skin-associated chemokine that preferentially attracts skin-homing memory T cells. Proc Natl Acad Sci U S A 96 14470-5. (1999)
67. Mota F, Rayment N, Chong S, Singer A. and Chain B, The antigen-presenting environment in normal and human papillomavirus (HPV)-related premalignant cervical epithelium. Clin Exp Immunol 116 33-40. (1999)
68. Mota F.F, Rayment N.B, Kanan J.H, Singer A. and Chain B.M, Differential regulation of HLA-DQ expression by keratinocytes and Langerhans cells in normal and premalignant cervical epithelium. Tissue Antigens 52 286-93. (1998)
69. Nestle F.O. and Burg G, Dendritic cells: role in skin diseases and therapeutic applications. Clin Exp Dermatol 24 204-7. (1999)
70. Ochsenbein A.F, Sierro S, Odermatt B, Pericin M, Karrer U, Hermans J, Hemmi S, Hengartner H. and Zinkernagel R.M, Roles of tumour localization second signals and cross priming in cytotoxic T-cell induction. Nature 411 1058-64. (2001)
71. Offringa R, van der Burg S.H, Ossendorp F, Toes R.E. and Melief C.J, Design and evaluation of antigen-specific vaccination strategies against cancer. Curr Opin Immunol 12 576-82. (2000)
72. Ohm J.E, Shurin M.R, Esche C, Lotze M.T, Carbone D.P. and Gabrilovich D.I, Effect of vascular endothelial growth factor and FLT3 ligand on dendritic cell generation in vivo. J Immunol 163 3260-8. (1999)
73. Palefsky J.M, Human papillomavirus-related tumors. AIDS 14 S189-95. (2000)
74. Pao C.C, Lin C.Y, Yao D.S. and Tseng C.J, Differential expression of cytokine genes in cervical cancer tissues. Biochem Biophys Res Commun 214 1146-51. (1995)
75. Pardoll D, T cells and tumours. Nature 411 1010-2. (2001)
76. Payne E, Bowles M.R, Don A, Hancock J.F. and McMillan N.A, Human papillomavirus type 6b virus-like particles are able to activate the Ras-MAP kinase pathway and induce cell proliferation. J Virol 75 4150-7. (2001)
77. Peguet-Navarro J, Moulon C, Caux C, Dalbiez-Gauthier C, Banchereau J. and Schmitt D, Interleukin-10 inhibits the primary allogeneic T cell response to human epidermal Langerhans cells. Eur J Immunol 24 884-91. (1994)
78. Poppe W.A, Drijkoningen M, Ide P.S, Lauweryns J.M. and Van Assche F.A, Langerhans' cells and L1 antigen expression in normal and abnormal squamous epithelium of the cervical transformation zone. Gynecol Obstet Invest 41 207-13 (1996)
79. Puts J.J, Moesker O, de Waal R.M, Kenemans P, Vooijs G.P. and Ramaekers F.C, Immunohistochemical identification of Langerhans cells in normal epithelium and in epithelial lesions of the uterine cervix. Int J Gynecol Pathol 5 151-62 (1986)
80. Qin Z, Noffz G, Mohaupt M. and Blankenstein T, Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells. J Immunol 159 770-6. (1997)
81. Rea D, Johnson M.E, Havenga M.J, Melief C.J. and Offringa R, Strategies for improved antigen delivery into dendritic cells. Trends Mol Med 7 91-4. (2001)
82. Reiss Y, Proudfoot A.E, Power C.A, Campbell J.J. and Butcher E.C, CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin. J Exp Med 194 1541-7. (2001)
83. Revaz V, Benyacoub J, Kast W.M, Schiller J.T, De Grandi P. and Nardelli-Haefliger D, Mucosal vaccination with a recombinant Salmonella typhimurium expressing human papillomavirus type 16 (HPV16) L1 virus-like particles (VLPs) or HPV16 VLPs purified from insect cells inhibits the growth of HPV16-expressing tumor cells in mice. Virology 279 354-60. (2001)
84. Ria F, Penna G. and Adorini L, Thl cells induce and Th2 inhibit antigen-dependent IL-12 secretion by dendritic cells. Eur J Immunol 28 2003-16. (1998)
85. Roncarolo M.G, Levings M.K. and Traversari C, Differentiation of T regulatory cells by immature dendritic cells. J Exp Med 193 F5-9. (2001)
86. Rudolf M.P, Fausch S.C, Da Silva D.M. and Kast W.M, Human dendritic cells are activated by chimeric human papillomavirus type-16 virus-like particles and induce epitope-specific human T cell responses in vitro. J Immunol 166 5917-24. (2001)
87. Sakaguchi S, Sakaguchi N, Shimizu J, Yamazaki S, Sakihama T, Itoh M, Kuniyasu Y, Nomura T, Toda M. and Takahashi T, Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity tumor immunity and transplantation tolerance. Immunol Rev 182 18-32. (2001)
88. Sales K.J, Katz A.A, Davis M, Hinz S, Soeters R.P, Hofmeyr M.D, Millar R.P. and Jabbour H.N, Cyclooxygenase-2 expression and prostaglandin E(2) synthesis are up-regulated in carcinomas of the cervix: a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors. J Clin Endocrinol Metab 86 2243-9. (2001)
89. Santin A.D, Hermonat P.L, Hiserodt J.C, Fruehauf J, Schranz V, Barclay D, Pecorelli S. and Parham G.P, Differential transforming growth factor-beta secretion in adenocarcinoma and squamous cell carcinoma of the uterine cervix. Gynecol Oncol 64 477-80. (1997)
90. Sasadeusz J, Kelly H, Szer J, Schwarer A.P, Mitchell H. and Grigg A, Abnormal cervical cytology in bone marrow transplant recipients. Bone Marrow Transplant 28 393-7. (2001)
91. Schiller J. and Lowy D, Papillomavirus-like particle vaccines. J Natl Cancer Inst Monogr 28 50-4 (2001)
92. Schuurhuis D.H, Laban S, Toes R.E, Ricciardi-Castagnoli P, Kleijmeer M.J, van der Voort E.I, Rea D, Offringa R, Geuze H.J, Melief C.J. and Ossendorp F, Immature dendritic cells acquire CD8(+) cytotoxic T lymphocyte priming capacity upon activation by T helper cell-independent or -dependent stimuli. J Exp Med 192 145-50. (2000)
93. Serraino D, Carrieri P, Pradier C, Bidoli E, Dorrucci M, Ghetti E, Schiesari A, Zucconi R, Pezzotti P, Dellamonica P, Franceschi S. and Rezza G, Risk of invasive cervical cancer among women with or at risk for HIV infection. Int J Cancer 82 334-7. (1999)
94. Shevach E.M, McHugh R.S, Piccirillo C.A. and Thornton A.M, Control of T-cell activation by CD4+ CD25+ suppressor T cells. Immunol Rev 182 58-67. (2001)
95. Steinbrink K, Jonuleit H, Muller G, Schuler G, Knop J. and Enk A.H, Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8(+) T cells resulting in a failure to lyse tumor cells. Blood 93 1634-42. (1999)
96. Steinbrink K, Wolfl M, Jonuleit H, Knop J. and Enk A.H, Induction of tolerance by IL-10-treated dendritic cells. J Immunol 159 4772-80. (1997)
97. Stern P.L, Brown M, Stacey S.N, Kitchener H.C, Hampson I, Abdel-Hady E.S. and Moore J.V, Natural HPV immunity and vaccination strategies. J Clin Virol 19 57-66. (2000)
98. Stoler M.H, Human papillomaviruses and cervical neoplasia: a model for carcinogenesis. Int J Gynecol Pathol 19 16-28. (2000)
99. Takano H, Harigaya K, Ishii G, Sugaya Y, Soeta S, Nunoyama T, Shirasawa H, Shimizu K, Tokita H, Simizu B, Mikata A. and Sekiya S, Interleukin-6 (IL-6) production in carcinoma of the cervix. Arch Gynecol Obstet 258 25-33 (1996)
100. Takeuchi M, Alard P. and Streilein J.W, TGF-beta promotes immune deviation by altering accessory signals of antigen-presenting cells. J Immunol 160 1589-97. (1998)
101. Tartour E, Gey A, Sastre-Garau X, Pannetier C, Mosseri V, Kourilsky P. and Fridman W.H, Analysis of interleukin 6 gene expression in cervical neoplasia using a quantitative polymerase chain reaction assay: evidence for enhanced interleukin 6 gene expression in invasive carcinoma. Cancer Res 54 6243-8. (1994)
102. Tay S.K, Jenkins D, Maddox P, Campion M. and Singer A, Subpopulations of Langerhans' cells in cervical neoplasia. Br J Obstet Gynaecol 94 10-5. (1987)
103. Tervahauta A, Syrjanen S, Yliskoski M, Gold L.I. and Syrjanen K, Expression of transforming growth factor-beta 1 and -beta 2 in human papillomavirus (HPV)-associated lesions of the uterine cervix. Gynecol Oncol 54 349-56. (1994)
104. Tjiong M.Y, Out T.A, Ter Schegget J, Burger M.P. and Van Der Vange N, Epidemiologic and mucosal immunologic aspects of HPV infection and HPV-related cervical neoplasia in the lower female genital tract: a review. Int J Gynecol Cancer 11 9-17. (2001)
105. Tohyama M, Shirakara Y, Yamasaki K, Sayama K. and Hashimoto K, Differentiated keratinocytes are responsible for TNF-alpha regulated production of macrophage inflammatory protein 3alpha/CCL20 a potent chemokine for Langerhans cells. J Dermatol Sci 27 130-9. (2001)
106. Vambutas A, DeVoti J, Pinn W, Steinberg B.M. and Bonagura V.R, Interaction of human papillomavirus type 11 E7 protein with TAP-1 results in the reduction of ATP-dependent peptide transport. Clin Immunol 101 94-9. (2001)
107. van der Burg S.H, Kwappenberg K.M, O'Neill T, Brandt R.M, Melief C.J, Hickling J.K. and Offringa R, Pre-clinical safety and efficacy of TA-CIN a recombinant HPV16 L2E6E7 fusion protein vaccine in homologous and heterologous prime-boost regimens. Vaccine 19 3652-60. (2001)
108. Vezys V, Olson S. and Lefrancois L, Expression of intestine-specific antigen reveals novel pathways of CD8 T cell tolerance induction. Immunity 12 505-14. (2000)
109. Viac J, Guerin-Reverchon I, Chardonnet Y. and Bremond A, Langerhans cells and epithelial cell modifications in cervical intraepithelial neoplasia: correlation with human papillomavirus infection. Immunobiology 180 328-38. (1990)
110. zur Hausen H, Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis. J Natl Cancer Inst 92 690-8. (2000)
111. Zwaveling S, Ferreira-Mota S.C, Nouta J, Johnson M, Lipford G.B, Offringa R, Van der Burg S.H, Melief C.J.M, Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides. J Immunol 169 350-8. (2002)