Expression of vascular endothelial growth factor (VEGF) and its mRNA in uterine cervical cancers

British Journal of Cancer

Volumn 80, Issue 5-6, 1999, Pages 827-833

  Fujimoto, J ^a   Sakaguchi, H ^a   Hirose, R ^a   Ichigo, S ^a   Tamaya, T ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cervical cancer; Neovascularization; VEGF

Indexed keywords

MESSENGER RNA; VASCULOTROPIN;

ADULT; AGED; ARTICLE; ENZYME IMMUNOASSAY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING; UTERINE CERVIX CANCER; WESTERN BLOTTING;

EID: 0032944507     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690428     Document Type: Article

References (39)

1. Arcari P, Martinelli R and Salvatore F (1984) The complete sequences of a full length cDNA for human liver glyceraldehyde 3-phosphate dehydrogenase: evidence for multiple mRNA species. Nucleic Acids Res 12: 9179-9189
2. Berkman RA, Merrill MJ, Reinhold WC, Monacci WT, Saxena A, Clark WC, Robertson JT, Ali IU and Oldfield EH (1993) Expression of vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms. J Clin Invest 91: 153-159
3. Bradford M (1976) A rapid and sensitive method for the quantilalion of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 315-323
4. Cheng SY, Nagane M, Huang HS and Cavenee WK (1997) Intracerebral tumor-associated hemorrhage caused by overexpression of the vascular endothelial growth factor isoforms VEGF121 and VEGF165 but not VEGF189. Proc. Natl Acad Sci USA 94: 12081-12087
5. Chomezynski P and Sacchi N (1987) Single-step method of RNA isolation by acid guanidium thiocyanate-phenol chloroform extraction. Anal Biochem 162: 156-159
6. Denekamp J (1984) Vascular as a target for tumor therapy. Prog Appl Microcirc 4: 28-38
7. Dobbs SP, Hewett PW, Johnson IR, Carmichael J and Murray JC (1997) Angiogenesis is associated with vascular endothelial growth factor expression in cervical intraepithelial neoplasia. Br J Cancer 76: 1410-1415
8. FIGO News (1989) Int J Gynecol Obstet 28: 189-193
9. Folkman J (1985) Tumor angiogenesis. Adv Cancer Res 43: 175-203
10. Folkman J and Haudenschild C (1980) Angiogenesis in vitro. Nature 288: 551-556
11. Folkman J and Ingber DE (1987) Angiostatic steroids. Ann Surg 206: 374-383
12. Fujimoto J, Hosoda S, Fujita H and Okada H (1989) Inhibition of tumor angiogenesis activity by medroxyprogesterone acetate in gynecologic manlignant tumors. Invasion Metastasis 9: 269-277
13. Fujimoto J, Ichigo S, Hori M, Hirose R, Sakaguchi H and Tamaya T (1997) Expression of basic flbroblast growth factor and its mRNA in advanced uterine cervical cancers. Cancer Lett 111: 21-26
14. Fujimoto J, Sakaguchi H, Hirose R, Ichigo S and Tamaya T (1998a) Biological implication of the expression of vascular endothelial growth factor in ovarian cancers. Cancer 83: 2528-2533
15. Fujimoto J, Sakaguchi H, Hirose R and Tamaya T (1998b) Expression of vascular endothelial growth factor (VEGF) and its mRNA in uterine endometrial cancers. Cancer Lett 134: 15-22
16. Fujimoto J, Ichigo S, Sakaguchi H, Hirose R and Tamaya T (1999) Expression of platelet-derived endothelial cell growth factor (PD-ECGF) and its mRNA in uterine cervical cancers. Br J Cancer 79: 1249-1254
17. Garrido C, Saule S and Gospodarowiez D (1993) Transcriptional regulation of vascular endothelial growth factor gene expression in ovarian bovine granulosa cells. Growth Factor 8: 109-117
18. Guidi AJ, Abu-Jawdeh G, Berse B, Jackman RW, Tognazzi K, Dvorak HF and Brown LF (1995) Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia. J Natl Cancer Inst 87: 1237-1245
19. Guidi AJ, Abu-Jawdeh G, Tognazzi K, Dvorak HF and Brown LF (1996) Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in endometrial cancers. Cancer 78: 454-460
20. Houck KA, Ferrara N, Winer J, Cachianes G, LI B and Leung DW (1991) The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol Endocrinol 12: 1806-1814
21. Ingber D, Fijita T, Kishimoto S, Sudo K, Kanamaru T, Brem H and Folkman J (1990) Synthetic analog of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature 348: 555-557
22. Jackson MR, Carney EW, Lye SJ and Knoxritchie JW (1994) Localization of two angiogenic growth factors (PDECGF and VEGF) in human placentae throughout gestation. Placenta 15: 341-353
23. Keck PJ, Hauser SD, Krivi G, Sanzo K, Warren T, Feder J and Connolly DT (1989) Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 246: 1309-1312
24. Leung DW, Cachianes G, Kuang W-J, Goeddel DV and Ferrara N (1989) Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246: 1306-1309
25. Li XF, Gregory J and Ahmed A (1994) Immunolocalization of vascular endothelial growth factor in human endometrium. Growth Factor 11: 277-282
26. Macchiarini P, Fontanini G, Hardin MJ, Squartini F and Angeletti GA (1992) Relation of neovascularization to metastasis of non-small-cell lung cancer. Lancet 340: 145-146
27. Maeda K, Chung YS, Ogawa Y, Takatsuka S, Kang SM, Ogawa M, Sawada T, Onoda N, Kato Y and Sowa M (1996) Thymidine phosphorylase/platelet-derived endothelial cell growth factor expression associated with hepatic-metastasis in gastric carcinoma. Br J Cancer 73: 884-888
28. Olson TA, Mohanraj D, Carson LF and Ramakrishnan S (1994) Vascular permeability factor gene expression in normal and neoplastic human ovaries. Cancer Res 54: 276-280
29. Oshika Y, Nakamura M, Tokunaga T, Ozeki Y, Fukushima Y, Hatanaka H, Ahe Y, Yamazaki H, Kijima H, Tamaoki N and Ueyama Y (1998) Expression of cell-associated isoform of vascular endothelial growth factor 189 and its prognostic relevance in non-small cell lung cancer. Int J Oncol 12: 541-544
30. Poltorak Z, Cohen T, Sivan R, Kandelis Y, Spira G, Vlodavsky I, Keshet E and Neufeld G (1997) VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix. J Biol Chem 272: 7151-7158
31. Scott PA, Smith K, Poulsom R, DE Benedetti A, Bicknell R and Harris AL (1998) Differential expression of vascular endothelial growth factor mRNA vs protein isoform expression in human breast cancer and relationship to elF-4E. Br J Cancer 77: 2120-2128
32. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS and Dvorak HS (1983) Tumor cells secrete a vascular permeability factor that promotes accumutation of ascites fluid. Science 219: 983-985
33. Srivastava A, Laidler P, Davies RP, Horgan K and Hughes L (1988) The prognostic significance of tumor vascularity in intermediate-thickness (0.76-4.0 mm thick) skin melanoma. Am J Pathol 133: 419-423
34. Tokumo K, Kodama J, Seki N, Nakanishi Y, Miyagi Y, Kaminuma S, Yoshinouchi M, Okuda H and Kudo T (1998) Different angiogenic pathways in human cervical cancers. Gynecol Oncol 68: 38-44
35. Tokunaga T, Oshika Y, Abe Y, Ozeki Y, Sadahiro S, Kijima H, Tsucida T, Yamazaki H, Ueyuma Y, Tamaoki N and Nakamura M (1998) Vascular endothelial growth factor (VEGF) mRNA isoform expression pattern is correlated with liver metastasis and poor prognosis in colon cancer. Br J Cancer 77: 998-1002
36. Wakui S, Furusato M, Itoh T, Sasaki H, Akiyama A, Kinoshita I, Asano K, Tokuda T, Aizawa S and Ushigotne S (1992) Tumor angiogenesis in prostatic carcinoma with and without bone marrow metastasis: a morphometric study. J Pathol 168: 257-262
37. Warren RS, Yuan H, Matli MR, Gilett NA and Ferrara N (1995) Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse of experimental liver metastasis. J Clin Invest 95: 1789-1797
38. Weidner N, Semple JP, Welch WR and Folkman J (1991) Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N Engl J Med 324: 1-7
39. Weidner N, Carroll PR, Flax J, Blumenfeld W and Folkman J (1993) Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol 143: 401-409