Transfection and overexpression of metallothionein-I in neonatal rat primary astrocyte cultures and in astrocytoma cells increases their resistance to methylmercury-induced cytotoxicity

Brain Research

Volumn 818, Issue 2, 1999, Pages 414-420

  Yao, Chang Ping ^a   Allen, Jeffrey W ^a   Conklin, Dawn R ^a   Aschner, Michael ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Astrocyte; Astrocytoma; Glial fibrillary acidic protein; Metallothionein I; Methylmercury

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; METALLOTHIONEIN; METHYLMERCURY;

ANIMAL CELL; ARTICLE; ASTROCYTE; ASTROCYTOMA CELL; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; MERCURIALISM; NEUROTOXICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; ASTROCYTOMA; CELL SURVIVAL; CELLS, CULTURED; DRUG RESISTANCE; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIAL FIBRILLARY ACIDIC PROTEIN; METALLOTHIONEIN; METHYLMERCURY COMPOUNDS; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; TRANSFECTION;

EID: 0008906081     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)01229-3     Document Type: Article

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