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Volumn 3, Issue 5, 2000, Pages 512-517

Monobactams as enzyme inhibitors

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[No Author keywords available]

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EID: 0001651114     PISSN: 13697056     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (22)

References (48)
  • 1
    • 0025364110 scopus 로고
    • Recent developments in inhibiting cysteine and serine proteases
    • Demuth HU: Recent developments in inhibiting cysteine and serine proteases. J Enzyme Inhib (1990) 3:249-278.
    • (1990) J Enzyme Inhib , vol.3 , pp. 249-278
    • Demuth, H.U.1
  • 2
    • 0031189711 scopus 로고    scopus 로고
    • Molecular recognition of protein-ligand complexes: Application to drug design
    • Babine RE, Bender SL: Molecular recognition of protein-ligand complexes: Application to drug design. Chem Rev (1997) 97:1359-1472.
    • (1997) Chem Rev , vol.97 , pp. 1359-1472
    • Babine, R.E.1    Bender, S.L.2
  • 3
    • 0029665670 scopus 로고    scopus 로고
    • New concept in biochemistry-from poor substrate to good inhibitors: Design of inhibitors for serine and thiol proteases
    • Baggio R, Shi YQ, Wu Y, Abels RH: New concept in biochemistry-from poor substrate to good inhibitors: Design of inhibitors for serine and thiol proteases. Biochemistry (1996) 35:3351-3353.
    • (1996) Biochemistry , vol.35 , pp. 3351-3353
    • Baggio, R.1    Shi, Y.Q.2    Wu, Y.3    Abels, R.H.4
  • 4
    • 0033550261 scopus 로고    scopus 로고
    • Synthesis, reactivity and biochemical evaluation of 1,3-substituted azetidin-2-ones as enzyme inhibitors
    • Beauve C, Bouchet M, Touillaux R, Fastrez J, Marchand-Brynaert J: Synthesis, reactivity and biochemical evaluation of 1,3-substituted azetidin-2-ones as enzyme inhibitors. Tetrahedron (1999) 55:13301-13320.
    • (1999) Tetrahedron , vol.55 , pp. 13301-13320
    • Beauve, C.1    Bouchet, M.2    Touillaux, R.3    Fastrez, J.4    Marchand-Brynaert, J.5
  • 6
    • 0007988352 scopus 로고
    • Evolution of DD-peptidases and β-lactamase
    • Actor P, Daneo-Moore L, Higgins ML, Salton MRJ, Shockmon GD (Eds), American Society of Microbiology, Washington, DC, USA
    • Ghuysen JM: Evolution of DD-peptidases and β-lactamase. In: Antibiotic inhibition of bacterial cell surface assembly and function, Actor P, Daneo-Moore L, Higgins ML, Salton MRJ, Shockmon GD (Eds), American Society of Microbiology, Washington, DC, USA, (1988) 268-284.
    • (1988) Antibiotic Inhibition of Bacterial Cell Surface Assembly and Function , pp. 268-284
    • Ghuysen, J.M.1
  • 7
    • 0025761016 scopus 로고
    • Evolution of β-lactamase inhibitors
    • Rolinson GN: Evolution of β-lactamase inhibitors. Rev Infect Dis (1991) 13 (Suppl 9):S727-732.
    • (1991) Rev Infect Dis , vol.13 , Issue.9 SUPPL.
    • Rolinson, G.N.1
  • 8
    • 0344176170 scopus 로고    scopus 로고
    • β-lactamase inhibitors and β-lactam antibiotics: Patent highlights June 1998 to November 1998
    • Maiti SN, Phillips OA: β-lactamase inhibitors and β-lactam antibiotics: patent highlights June 1998 to November 1998. Curr Opin Anti-Infective Invest Drugs (1999) 1:40-44.
    • (1999) Curr Opin Anti-Infective Invest Drugs , vol.1 , pp. 40-44
    • Maiti, S.N.1    Phillips, O.A.2
  • 11
    • 33747266932 scopus 로고    scopus 로고
    • SYN-2190: A novel potent β-lactamase inhibitor: kinetics of enzyme inhibition and penetration of the Pseudomonas aeruginosa outer membrane
    • Toronto F189
    • Atchison KP, Catena R, Kaleta J, Atwal H, Maiti SN, Micetich RG: SYN-2190: a novel potent β-lactamase inhibitor: kinetics of enzyme inhibition and penetration of the Pseudomonas aeruginosa outer membrane. ICAAC (1997) 37 Toronto F189.
    • (1997) ICAAC , vol.37
    • Atchison, K.P.1    Catena, R.2    Kaleta, J.3    Atwal, H.4    Maiti, S.N.5    Micetich, R.G.6
  • 12
    • 33747228663 scopus 로고    scopus 로고
    • SYN-2190: A novel potent β-lactamase inhibitor: in vitro activity in combination with ceftazidime, cefozopran, cefepime and cefpirome against β-lactamase producing strains and ceftazidime-resistant clinical isolates
    • Toronto F190
    • Kunugita C, Nishida K, Uji T, Salama SM, Atwal H, Maiti SN, Micetich RG, Unemi N: SYN-2190: a novel potent β-lactamase inhibitor: in vitro activity in combination with ceftazidime, cefozopran, cefepime and cefpirome against β-lactamase producing strains and ceftazidime-resistant clinical isolates. ICAAC (1997) 37 Toronto F190.
    • (1997) ICAAC , vol.37
    • Kunugita, C.1    Nishida, K.2    Uji, T.3    Salama, S.M.4    Atwal, H.5    Maiti, S.N.6    Micetich, R.G.7    Unemi, N.8
  • 13
    • 33747227538 scopus 로고    scopus 로고
    • SYN-2190: A novel potent β-lactamase inhibitor: in vivo activity in combination with cephalosporins against class C β-lactamase producing strains
    • Toronto F192
    • Nishida K, Nishiyama T, Urata K, Hirakawa Y, Komuro M, Higashitani F, Khan JK, Maiti SN, Micetich RG, Unemi N: SYN-2190: a novel potent β-lactamase inhibitor: in vivo activity in combination with cephalosporins against class C β-lactamase producing strains. ICAAC (1997) 37 Toronto F192.
    • (1997) ICAAC , vol.37
    • Nishida, K.1    Nishiyama, T.2    Urata, K.3    Hirakawa, Y.4    Komuro, M.5    Higashitani, F.6    Khan, J.K.7    Maiti, S.N.8    Micetich, R.G.9    Unemi, N.10
  • 14
    • 77956791952 scopus 로고
    • Human leukocyte elastase inhibitors
    • Bristol JA (Ed), Academic Press, New York
    • Hlasta DJ and Pagani EJ: Human leukocyte elastase inhibitors. In: Annual Report in Medicinal Chemistry. Bristol JA (Ed), Academic Press, New York (1994) 195-204.
    • (1994) Annual Report in Medicinal Chemistry , pp. 195-204
    • Hlasta, D.J.1    Pagani, E.J.2
  • 15
  • 16
    • 0031871150 scopus 로고    scopus 로고
    • 2-Spirocyclopropyl cephem sulfones: Human neutrophil elastase inhibitors Syn-1390 and Syn-1396
    • Maiti SN, Woods DE and Cantin AM: 2-Spirocyclopropyl cephem sulfones: human neutrophil elastase inhibitors Syn-1390 and Syn-1396. Drugs Future (1998) 23:635-641.
    • (1998) Drugs Future , vol.23 , pp. 635-641
    • Maiti, S.N.1    Woods, D.E.2    Cantin, A.M.3
  • 18
    • 0029839451 scopus 로고    scopus 로고
    • An asymétrie synthesis of L-694,458, a human leukocyte elastase inhibitor, via novel enzyme resolution of β-lactam esters
    • Cvetovich RJ, Chartrain M, Harter Jr FW, Roberge C, Arnato JS, Grabowski EJJ: An asymétrie synthesis of L-694,458, a human leukocyte elastase inhibitor, via novel enzyme resolution of β-lactam esters. J Org Chem (1996) 61:6575-6580.
    • (1996) J Org Chem , vol.61 , pp. 6575-6580
    • Cvetovich, R.J.1    Chartrain, M.2    Harter Jr., F.W.3    Roberge, C.4    Arnato, J.S.5    Grabowski, E.J.J.6
  • 25
    • 0000058254 scopus 로고
    • Assemblin, a herpes virus serine maturational proteinases and new molecular target for antiviral
    • Gibson W, Welch AR, Hall MRT: Assemblin, a herpes virus serine maturational proteinases and new molecular target for antiviral. Perspec Drug Disc Des (1994) 2:413-426.
    • (1994) Perspec Drug Disc des , vol.2 , pp. 413-426
    • Gibson, W.1    Welch, A.R.2    Hall, M.R.T.3
  • 26
    • 0030923941 scopus 로고    scopus 로고
    • Herpevirus proteases: Targets for novel drugs
    • Holwerda, BC: Herpevirus proteases: targets for novel drugs. Antiviral Res (1997) 35:1-21.
    • (1997) Antiviral Res , vol.35 , pp. 1-21
    • Holwerda, B.C.1
  • 30
    • 0031807565 scopus 로고    scopus 로고
    • Cathepsin B inhibitors as potential antimetastatic agents
    • Milchaud S, Gour BJ: Cathepsin B inhibitors as potential antimetastatic agents. Exp Opin Ther Pat (1998) 8:645-672.
    • (1998) Exp Opin Ther Pat , vol.8 , pp. 645-672
    • Milchaud, S.1    Gour, B.J.2
  • 31
    • 0032972436 scopus 로고    scopus 로고
    • Cathepsin K as target for the treatment of osteoporosis
    • Smith WW, Abdel-Meguid SS: Cathepsin K as target for the treatment of osteoporosis. Exp Opin Ther Pat (1999) 9:683-694.
    • (1999) Exp Opin Ther Pat , vol.9 , pp. 683-694
    • Smith, W.W.1    Abdel-Meguid, S.S.2
  • 33
    • 0028062908 scopus 로고
    • A comparison of 4 ultrasensitive prostate specific antigen assays for early detection of residual cancer after radical prostatectomy
    • Prestigiacomo AF, Stamey TA: A comparison of 4 ultrasensitive prostate specific antigen assays for early detection of residual cancer after radical prostatectomy. J Urol (1994) 152:1515-1519.
    • (1994) J Urol , vol.152 , pp. 1515-1519
    • Prestigiacomo, A.F.1    Stamey, T.A.2
  • 34
    • 0028244093 scopus 로고
    • Development of highly selective immunochemiluminometric assay for prostate-specific antigen
    • Klee GG, Preissner CM, Oesterling JE: Development of highly selective immunochemiluminometric assay for prostate-specific antigen. Urology (1994) 44:76-82.
    • (1994) Urology , vol.44 , pp. 76-82
    • Klee, G.G.1    Preissner, C.M.2    Oesterling, J.E.3
  • 35
    • 0028048974 scopus 로고
    • Biological effects of prostate specific antigen as an insulin like growth factor binding protein-3 protease
    • Cohen P, Peehl DM, Graves HCB, Rosenfield RG: Biological effects of prostate specific antigen as an insulin like growth factor binding protein-3 protease. J Endocrinol (1994) 142:407-415.
    • (1994) J Endocrinol , vol.142 , pp. 407-415
    • Cohen, P.1    Peehl, D.M.2    Graves, H.C.B.3    Rosenfield, R.G.4
  • 36
    • 0029986601 scopus 로고    scopus 로고
    • Purification, properties, sequencing and cloning of a lipoprotein-associated, serine dependent phospholipase involved in the oxidative modification of low-density lipoproteins
    • Tew DG, Southan C, Rice SQ, Lawrence MP, Li H, Boyd HF, Moores K, Gloger IS, Macphee CH: Purification, properties, sequencing and cloning of a lipoprotein-associated, serine dependent phospholipase involved in the oxidative modification of low-density lipoproteins. Arterioscler Thromb Vase Biol (1996) 16:591-599.
    • (1996) Arterioscler Thromb Vase Biol , vol.16 , pp. 591-599
    • Tew, D.G.1    Southan, C.2    Rice, S.Q.3    Lawrence, M.P.4    Li, H.5    Boyd, H.F.6    Moores, K.7    Gloger, I.S.8    Macphee, C.H.9
  • 37
    • 0027996669 scopus 로고
    • Alteration of lysophosphosphatidylcholine content in low density lipoprotein after oxidative modification: Relationship to endothelium dependent relaxation
    • Liu SY, Lu X, Choy S, Dembinski TC, Hatch GM, Mymin D, Shen X, Angel A, Choy PC, Man RYK: Alteration of lysophosphosphatidylcholine content in low density lipoprotein after oxidative modification: relationship to endothelium dependent relaxation. Cardiovasc Res (1994) 28:1476-1481.
    • (1994) Cardiovasc Res , vol.28 , pp. 1476-1481
    • Liu, S.Y.1    Lu, X.2    Choy, S.3    Dembinski, T.C.4    Hatch, G.M.5    Mymin, D.6    Shen, X.7    Angel, A.8    Choy, P.C.9    Man, R.Y.K.10
  • 40
    • 33747277868 scopus 로고    scopus 로고
    • 4-Substituted-3-peptidyl-azetidin-2-one derivatives useful as cysteine proteinase inhibitor. WO-09632408 (1996)
    • SYNPHAR LABORATORIES INC (Singh R, Zhou NE, Guo D, Micetich RG): 4-Substituted-3-peptidyl-azetidin-2-one derivatives useful as cysteine proteinase inhibitor. WO-09632408 (1996).
    • Singh, R.1    Zhou, N.E.2    Guo, D.3    Micetich, R.G.4
  • 41
    • 33747205675 scopus 로고    scopus 로고
    • 3,4-Disubstituted azetidin-2-one derivatives useful as cysteine proteinase regulators. WO-09812176 (1998), US-05959123 (1999)
    • SYNPHAR LABORATORIES INC (Singh R, Zhou NE, Guo D, Micetich RG): 3,4-Disubstituted azetidin-2-one derivatives useful as cysteine proteinase regulators. WO-09812176 (1998), US-05959123 (1999).
    • Singh, R.1    Zhou, N.E.2    Guo, D.3    Micetich, R.G.4
  • 42
    • 33747283847 scopus 로고    scopus 로고
    • 4-Substituted-3-(2-amino-2-cycloalkylmethyl)-acetamido azetidin-2-one derivatives as cysteine proteinase regulators. WO-09812210 (1998), US-05916887 (1999)
    • SYNPHAR LABORATORIES INC; NATIONAL RESEARCH COUNCIL (Singh R, Zhou NE, Purishima EO, Micetich RG): 4-Substituted-3-(2-amino-2-cycloalkylmethyl)-acetamido azetidin-2-one derivatives as cysteine proteinase regulators. WO-09812210 (1998), US-05916887 (1999).
    • Singh, R.1    Zhou, N.E.2    Purishima, E.O.3    Micetich, R.G.4
  • 43
    • 33747216964 scopus 로고    scopus 로고
    • Monobactam derivatives as cathepsin B, L, K and S inhibitors. WO-09948911 (1999)
    • SYNPHAR LABORATORIES INC (Singh R, Zhou NE, Reddy AVN, Micetich RG): Monobactam derivatives as cathepsin B, L, K and S inhibitors. WO-09948911 (1999).
    • Singh, R.1    Zhou, N.E.2    Reddy, A.V.N.3    Micetich, R.G.4
  • 45
    • 33747280514 scopus 로고    scopus 로고
    • Azetidinone derivatives for the treatment of antherosclerosis. WO-09613484 (1996)
    • SMITHKLINE BEECHAM PLC (Mickey DMB, Dhanak D, Leach CA, Ife RJ, Tew DG): Azetidinone derivatives for the treatment of antherosclerosis. WO-09613484 (1996).
    • Mickey, D.M.B.1    Dhanak, D.2    Leach, C.A.3    Ife, R.J.4    Tew, D.G.5
  • 46
    • 33747260963 scopus 로고    scopus 로고
    • Substituted azetidin-2-ones for the treatment of atherosclerosis. WO-0961945 (1996)
    • SMITHKLINE BEECHAM PLC (Hickey DMB, Dhanak D, Leach CA, Ife RJ, Tew DG): Substituted azetidin-2-ones for the treatment of atherosclerosis. WO-0961945 (1996).
    • Hickey, D.M.B.1    Dhanak, D.2    Leach, C.A.3    Ife, R.J.4    Tew, D.G.5
  • 47
    • 33747284495 scopus 로고    scopus 로고
    • Monocyclic β-lactam derivatives for the treatment of atherosclerosis. WO-09721675 (1997)
    • SMITHKLINE BEECHAM PLC (Hickey DMB, Dhanak D, Ife RJ, Leach CA, Tew DG): Monocyclic β-lactam derivatives for the treatment of atherosclerosis. WO-09721675 (1997).
    • Hickey, D.M.B.1    Dhanak, D.2    Ife, R.J.3    Leach, C.A.4    Tew, D.G.5
  • 48
    • 33747326332 scopus 로고    scopus 로고
    • Azetidinone compounds for the treatment of atherosclerosis. WO-09721676 (1997)
    • SMITHKLINE BEECHAM PLC (Hickey DMB, Dhanak D, Ife RJ, Leach CA, Tew DG): Azetidinone compounds for the treatment of atherosclerosis. WO-09721676 (1997).
    • Hickey, D.M.B.1    Dhanak, D.2    Ife, R.J.3    Leach, C.A.4    Tew, D.G.5


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