-
1
-
-
0030955346
-
Epidemiology of hepatitis C
-
ALTER MJ: Epidemiology of hepatitis C. Hepatology (1977) 26(3, Suppl. 1):62-65.
-
(1977)
Hepatology
, vol.26
, Issue.3 SUPPL. 1
, pp. 62-65
-
-
Alter, M.J.1
-
2
-
-
0001445884
-
Management of hepatitis C
-
NATIONAL INSTITUTE OF HEALTH CONSENSUS DEVELOPMENT CONFERENCE PANEL STATEMENT
-
NATIONAL INSTITUTE OF HEALTH CONSENSUS DEVELOPMENT CONFERENCE PANEL STATEMENT: Management of hepatitis C. Hepatology (1977) 26(3, Suppl. 1):2-10.
-
(1977)
Hepatology
, vol.26
, Issue.3 SUPPL. 1
, pp. 2-10
-
-
-
3
-
-
0030885818
-
Therapy of hepatitis C: Alpha interferon and ribavirin
-
REICHARD O, SCHVARCZ R, WEILAND O: Therapy of hepatitis C: alpha interferon and ribavirin. Hepatology (1977) 26(3, Suppl. 1):108-111.
-
(1977)
Hepatology
, vol.26
, Issue.3 SUPPL. 1
, pp. 108-111
-
-
Reichard, O.1
Schvarcz, R.2
Weiland, O.3
-
4
-
-
0028016286
-
The epidemiology of viral hepatitis in the United States
-
ALTER MJ, MAST EE: The epidemiology of viral hepatitis in the United States. Gastroenterol. Clin. North Am. (1994) 23:435-437.
-
(1994)
Gastroenterol. Clin. North Am
, vol.23
, pp. 435-437
-
-
Alter, M.J.1
Mast, E.E.2
-
5
-
-
0024509701
-
Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
-
CHOO Q-L, KUO G, WEINER AJ et al.: Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science (1989) 244:359-362. (Pubitemid 19117877)
-
(1989)
Science
, vol.244
, Issue.4902
, pp. 359-362
-
-
Choo, Q.-L.1
Kuo, G.2
Weiner, A.J.3
Overby, L.R.4
Bradley, D.W.5
Houghton, M.6
-
6
-
-
0024511734
-
An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis
-
KUOG,CHOOQ-L, ALTER HJ et al.:Anassay for circulating antibodies to a major etiologic virus of human non-A, non-B antibodies. Science (1989) 244:362-364. (Pubitemid 19117878)
-
(1989)
Science
, vol.244
, Issue.4902
, pp. 362-364
-
-
Kuo, G.1
Choo, Q.-L.2
Alter, H.J.3
Gitnick, G.L.4
Redeker, A.G.5
Purcell, R.H.6
Miyamura, T.7
Dienstag, J.L.8
Alter, M.J.9
Stevens, C.E.10
Tegtmeier, G.E.11
Bonino, F.12
Colombo, M.13
Lee, W.-S.14
Kuo, C.15
Berger, K.16
Shuster, J.R.17
Overby, L.R.18
Bradley, D.W.19
Houghton, M.20
more..
-
7
-
-
79961076484
-
-
INTERNATIONAL UNION OF MICROBIOLOGICAL SOCIETIES (7th Edition). Murphy FA, Fauquet CM, Bishop DHL et al. (Eds.), Springer-Verlag, New York
-
INTERNATIONAL UNION OF MICROBIOLOGICAL SOCIETIES: In: Virus Taxonomy (7th Edition). Murphy FA, Fauquet CM, Bishop DHL et al. (Eds.), Springer-Verlag, New York (1995):424-427.
-
(1995)
Virus Taxonomy
, pp. 424-427
-
-
-
8
-
-
0027403907
-
Equilibrium centrifugation studies of hepatitis C virus: Evidence for circulating immune complexes
-
HIJIKATA M, SHIMIZU YK, KATOHet al.: Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes. J. Virol. (1993) 67:1953-1958. (Pubitemid 23088368)
-
(1993)
Journal of Virology
, vol.67
, Issue.4
, pp. 1953-1958
-
-
Hijikata, M.1
Shimizu, Y.K.2
Kato, H.3
Iwamoto, A.4
Shih, J.W.5
Alter, H.J.6
Purcell, R.H.7
Yoshikura, H.8
-
11
-
-
0029938477
-
Identification of a highly conserved sequence element at the 3¢ terminus of hepatitis C virus genome RNA
-
KOLYKHALOV AA, FEINSTONE SM, RICE C: Identification of a highly conserved sequence element at the 3¢ terminus of hepatitis C virus genome RNA. J. Virol. (1996) 70:3363-3371.
-
(1996)
J. Virol
, vol.70
, pp. 3363-3371
-
-
Kolykhalov, A.A.1
Feinstone, S.M.2
Rice, C.3
-
12
-
-
0025991559
-
Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis
-
HIJIKATA M, KATO N, OOTSUYAMA Y, NAKAGAWA M, SHIMOTOHNO K: Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc. Natl. Acad. Sci. USA (1991) 88:5547-5551. (Pubitemid 21914782)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.13
, pp. 5547-5551
-
-
Hijikata, M.1
Kato, N.2
Ootsuyama, Y.3
Nakagawa, M.4
Shimotohno, K.5
-
13
-
-
0027442136
-
Characterization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia viruses
-
RALSTON R,THUDIUM K, BERGER Ket al.: Characterization of hepatitisCvirus envelope glycoprotein complexes expressed by recombinant vaccinia viruses. J. Virol. (1993) 67:6753-6761. (Pubitemid 23309145)
-
(1993)
Journal of Virology
, vol.67
, Issue.11
, pp. 6753-6761
-
-
Ralston, R.1
Thudium, K.2
Berger, K.3
Kuo, C.4
Gervase, B.5
Hall, J.6
Selby, M.7
Kuo, G.8
Houghton, M.9
Choo, Q.-L.10
-
14
-
-
0027171629
-
Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in HuH-7 cells
-
SHIH CM, LO SJ, MIYAMURA T, CHEN SY, LEE YW: Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in Huh-7 cells. J. Virol. (1993) 67:5823-5832. (Pubitemid 23277490)
-
(1993)
Journal of Virology
, vol.67
, Issue.10
, pp. 5823-5832
-
-
Shih, C.-M.1
Lo, S.J.2
Miyamura, T.3
Chen, S.-Y.4
Lee, Y.-H.W.5
-
15
-
-
0030589563
-
Suppression of apoptotic cell death by hepatitis C virus core protein
-
RAY RB, MEYER K, RAY R: Suppression of apoptotic cell death by hepatitis C virus core protein. Virology (1996) 176:182-185.
-
(1996)
Virology
, vol.176
, pp. 182-185
-
-
Ray, R.B.1
Meyer, K.2
Ray, R.3
-
16
-
-
11144357274
-
Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets
-
DOI 10.1073/pnas.94.4.1200
-
BARBA G,HARPER F,HARADA T et al.: HepatitisCvirus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets. Proc. Natl. Acad. Sci.USA(1997) 94:1200-1205. (Pubitemid 27087828)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.4
, pp. 1200-1205
-
-
Barba, G.1
Harper, F.2
Harada, T.3
Kohara, M.4
Goulinet, S.5
Matsuura, Y.6
Eder, G.7
Schaff, Zs.8
Chapman, M.J.9
Miyamura, T.10
Brechot, C.11
-
17
-
-
0029897323
-
Interaction between hepatitis C virus core protein and E1 envelope protein
-
LO SY, SELBY MJ, OU JH: Interaction between hepatitis C virus core protein and E1 envelope protein. J. Virol. (1996) 70:5177-5182. (Pubitemid 26240689)
-
(1996)
Journal of Virology
, vol.70
, Issue.8
, pp. 5177-5182
-
-
Lo, S.-Y.1
Selby, M.J.2
Ou, J.-H.3
-
18
-
-
0028151708
-
Processing of E1 and E2 glycoproteins of hepatitis C virus expressed in mammalian and insect cells
-
DOI 10.1006/viro.1994.1629
-
MATSUURA Y, SUZUKI T, SUZUKI R et al.: Processing of E1 and E2 glycoproteins of hepatitis C virus expressed in mammalian and insect cells. Virology (1994) 205:141-150. (Pubitemid 24360600)
-
(1994)
Virology
, vol.205
, Issue.1
, pp. 141-150
-
-
Matsuura, Y.1
Suzuki, T.2
Suzuki, R.3
Sato, M.4
Aizaki, H.5
Saito, I.6
Miyamura, T.7
-
19
-
-
0028040540
-
Complex processing and protein:protein interactions in the E2:NS2 region of HCV
-
SELBY MJ, GLAZER E, MASIARZ F, HOUGHTON M: Complex processing and protein:protein interactions in the E2:NS2 region of HCV. Virology (1994) 204:114-122.
-
(1994)
Virology
, vol.204
, pp. 114-122
-
-
Selby, M.J.1
Glazer, E.2
Masiarz, F.3
Houghton, M.4
-
20
-
-
0028354145
-
Hypervariable region of hepatitis C virus envelope glycoprotein (E2/NS1) in an agammaglobulinemic patient
-
KUMAR U, MONJARDINO J, THOMAS HC: Hypervariable region of hepatitis C virus envelope glycoprotein (E2/NS1) in a gammaglobulinemic patient. Gastroenterology (1994) 106:1072-1075. (Pubitemid 24109297)
-
(1994)
Gastroenterology
, vol.106
, Issue.4
, pp. 1072-1075
-
-
Kumar, U.1
Monjardino, J.2
Thomas, H.C.3
-
21
-
-
0026025737
-
Variable and hypervariable domains are found in the regions of HCV corresponding to the Flavivirus envelope and NS1 proteins and the Pestivirus envelope glycoproteins
-
WEINER AJ, BRAUER MJ, ROSENBLATT J et al.: Variable and hypervariable domains are found in the regions of HCV corresponding to the Flavivirus envelope and NS1 proteins and the Pestivirus envelope glycoproteins. Virology (1991) 180:842-848.
-
(1991)
Virology
, vol.180
, pp. 842-848
-
-
Weiner, A.J.1
Brauer, M.J.2
Rosenblatt, J.3
-
22
-
-
0026334457
-
Nucleotide sequence and mutation rate of the H strain of hepatitis C virus
-
OGATAN, ALTER HJ, MILLER RH, PURCELL RH: Nucleotide sequence and mutation rate of H strain of hepatitis C virus. Proc. Natl. Acad. Sci. USA (1991) 88:3392-3396. (Pubitemid 21916627)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.8
, pp. 3392-3396
-
-
Ogata, N.1
Alter, H.J.2
Miller, R.H.3
Purcell, R.H.4
-
23
-
-
0027163740
-
Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus
-
HIJIKATA M, MIZUSHIMA H, AKAGI et al.: Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of the hepatitisCvirus. J. Virol. (1993) 67:4665-4675. (Pubitemid 23215946)
-
(1993)
Journal of Virology
, vol.67
, Issue.8
, pp. 4665-4675
-
-
Hijikata, M.1
Mizushima, H.2
Akagi, T.3
Mori, S.4
Kakiuchi, N.5
Kato, N.6
Tanaka, T.7
Kimura, K.8
Shimotohno, K.9
-
24
-
-
0027436831
-
A second hepatitis C virus-encoded protease
-
GRAKOUI A, MCCOURT DW, WYCHOWSKI SM, FEINSTONE SM, RICE CM: A second hepatitis C virus-encoded protease. Proc. Natl. Acad. Sci. USA (1993) 90:10583-10587.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10583-10587
-
-
Grakoui, A.1
McCourt, D.W.2
Wychowski, S.M.3
Feinstone, S.M.4
Rice, C.M.5
-
25
-
-
0032031975
-
Mechanism of autoproteolysis at the NS2-NS3 junction of the hepatitis C virus polyprotein
-
PII S0968000498011803
-
WUZ,YAON, LE HV, WEBER PC: Mechanism of autoproteolysis at the NS2-NS3 junction of the hepatitis C virus polyprotein. Trends Biochem. Sci. (1998) 23:92-94. (Pubitemid 128712692)
-
(1998)
Trends in Biochemical Sciences
, vol.23
, Issue.3
, pp. 92-94
-
-
Wu, Z.1
Yao, N.2
Le, H.V.3
Weber, P.C.4
-
28
-
-
0028832632
-
TheNS2protein of hepatitis C virus is a transmembrane polypeptide
-
SANTOLIN IE, PACINI L, FIPALDINI C,MIGLIACCI OG,LAMONICA N: TheNS2protein of hepatitis C virus is a transmembrane polypeptide. J. Virol. (1995) 69:7461-7471.
-
(1995)
J. Virol
, vol.69
, pp. 7461-7471
-
-
Santolin, I.E.1
Pacini, L.2
Fipaldin, I.3
Cmigliacci, O.G.4
Lamonica, N.5
-
29
-
-
0030778811
-
Molecular virology of hepatitis C virus
-
CLARKE B: Molecular virology of hepatitis C virus. J. Gen. Virol. (1997) 78:2397-2410. (Pubitemid 27469980)
-
(1997)
Journal of General Virology
, vol.78
, Issue.10
, pp. 2397-2410
-
-
Clarke, B.1
-
30
-
-
0030861240
-
In vitro study of the NS2-3 protease of hepatitis c virus
-
PIERONI L, SANTOLINI E, FIPALDINI C et al.: In vitro study of the NS2-3 protease of hepatitis C virus. J. Virol. (1997) 71:6373-6380. (Pubitemid 27355290)
-
(1997)
Journal of Virology
, vol.71
, Issue.9
, pp. 6373-6380
-
-
Pieroni, L.1
Santolini, E.2
Fipaldini, C.3
Pacini, L.4
Migliaccio, G.5
La Monica, N.6
-
31
-
-
0027414062
-
Characterization of the hepatitis C virus-encoded serine proteinase: Determination of proteinase-dependent polyprotein cleavage sites
-
GRAKOUI A, MCCOURT DW, WYCHOWSKI SM, FEINSTONE SM, RICE CM: Characterization of the hepatitis C virus-encoded serine proteinase: determination of the proteinase-dependent polyprotein cleavage sites. J. Virol. (1993) 67:2832-2843. (Pubitemid 23118883)
-
(1993)
Journal of Virology
, vol.67
, Issue.5
, pp. 2832-2843
-
-
Grakoui, A.1
McCourt, D.W.2
Wychowski, C.3
Feinstone, S.M.4
Rice, C.M.5
-
32
-
-
0028290579
-
Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins
-
FAILLA C, TOMEI L, DE FRANCESCO R: Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins. J. Virol. (1994) 68:3753-3760. (Pubitemid 24177400)
-
(1994)
Journal of Virology
, vol.68
, Issue.6
, pp. 3753-3760
-
-
Failla, C.1
Tomei, L.2
De Francesco, R.3
-
33
-
-
0032502277
-
Serine protease of hepatitis C virus expressed in insect cells as the NS3/4A complex
-
DOI 10.1021/bi972010r
-
SALI DL, INGRAM R, WENDEL M et al.: Serine protease of hepatitis C virus expressed in insect cells as the NS3/4A complex. Biochemistry (1998) 37:3392-3401. (Pubitemid 28125567)
-
(1998)
Biochemistry
, vol.37
, Issue.10
, pp. 3392-3401
-
-
Sali, D.L.1
Ingram, R.2
Wendel, M.3
Gupta, D.4
McNemar, C.5
Tsarbopoulos, A.6
Chen, J.W.7
Hong, Z.8
Chase, R.9
Risano, C.10
Zhang, R.11
Yao, N.12
Kwong, A.D.13
Ramanathan, L.14
Le, H.V.15
Weber, P.C.16
-
34
-
-
0030844455
-
Probing the substrate specificity of hepatitis C virus NS3 serine protease by using synthetic peptides
-
ZHANG R, DURKIN J, WINDSOR WTet al.: Probing the substrate specificity of hepatitis C virus NS3 serine protease by using synthetic peptides. J. Virol. (1997) 71:6208-6213. (Pubitemid 27304966)
-
(1997)
Journal of Virology
, vol.71
, Issue.8
, pp. 6208-6213
-
-
Zhang, R.1
Durkin, J.2
Windsor, W.T.3
McNemar, C.4
Ramanathan, L.5
Le, H.V.6
-
35
-
-
0030592514
-
The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site
-
DOI 10.1016/S0092-8674(00)81350-1
-
LOVE RA, PARGE HE, WICKERSHAM JA et al.: The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site. Cell (1996) 87:331-342. (Pubitemid 26359010)
-
(1996)
Cell
, vol.87
, Issue.2
, pp. 331-342
-
-
Love, R.A.1
Parge, H.E.2
Wickersham, J.A.3
Hostomsky, Z.4
Habuka, N.5
Moomaw, E.W.6
Adachi, T.7
Hostomska, Z.8
-
36
-
-
16044364658
-
Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide
-
DOI 10.1016/S0092-8674(00)81351-3
-
KIM JL, MORGENSTERN C, LIN T et al.: Crystal structure of the hepatitis C virus NS3 protease domain complexed with a syntheticNS4Acofactor peptide. Cell (1996) 87:343-355. (Pubitemid 26359011)
-
(1996)
Cell
, vol.87
, Issue.2
, pp. 343-355
-
-
Kim, J.L.1
Morgenstern, K.A.2
Lin, C.3
Fox, T.4
Dwyer, M.D.5
Landro, J.A.6
Chambers, S.P.7
Markland, W.8
Lepre, C.A.9
O'Malley, E.T.10
Harbeson, S.L.11
Rice, C.M.12
Murcko, M.A.13
Caron, P.R.14
Thomson, J.A.15
-
37
-
-
2642590958
-
Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: A 2.2 Å resolution structure in a hexagonal crystal form
-
YAN Y, LI Y, MUNSHI S et al.: Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: a 2.2 Å resolution structure in a hexagonal crystal form. Protein Sci. (1998) 7:837-847.
-
(1998)
Protein Sci
, vol.7
, pp. 837-847
-
-
Yan, Y.1
Y, L.I.2
Munshi, S.3
-
38
-
-
0027199917
-
Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes
-
SUZICH JA, TAMURA JK, PALMER-HILL F et al.: Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related Pestivirus and Flavivirus enzymes. J. Virol. (1993) 67:6152-6158. (Pubitemid 23277527)
-
(1993)
Journal of Virology
, vol.67
, Issue.10
, pp. 6152-6158
-
-
Suzich, J.A.1
Tamura, J.K.2
Palmer-Hill, F.3
Warrener, P.4
Grakoui, A.5
Rice, C.M.6
Feinstone, S.M.7
Collett, M.S.8
-
39
-
-
0029784485
-
A steady-state and pre-steady-state kinetic analysis of the NTPase activity associated with the hepatitis C virus NS3 helicase domain
-
DOI 10.1074/jbc.271.40.24449
-
PREUGSCHAT F, AVERETT DR, CLARKE BE, PORTER DJT: A steady-state and pre-steady-state kinetic analysis of the NTPase activity associated with the hepatitis C virus NS3 helicase domain. J. Biol. Chem. (1996) 271:24449-24457. (Pubitemid 26333179)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.40
, pp. 24449-24457
-
-
Preugschat, F.1
Averett, D.R.2
Clarke, B.E.3
Porter, D.J.T.4
-
40
-
-
0029970903
-
The helicase activity associated with hepatitis C virus nonstructural protein 3 (NS3)
-
TAI C-L, CHI W-K, CHEN D-S, HWANG L-H: The helicase activity associated with hepatitis C virus non structural protein 3 (NS3). J. Virol. (1996) 70:8477-8484. (Pubitemid 26378425)
-
(1996)
Journal of Virology
, vol.70
, Issue.12
, pp. 8477-8484
-
-
Tai, C.-L.1
Chi, W.-K.2
Chen, D.-S.3
Hwang, L.-H.4
-
41
-
-
0013627747
-
Mutational analysis of the hepatitis C virus RNA helicase
-
KIM DW, KIM J,GWACK Y,HAN JH, CHOE J: Mutational analysis of the hepatitis C virus RNA helicase. J. Virol. (1997) 71:9400-9409. (Pubitemid 27492383)
-
(1997)
Journal of Virology
, vol.71
, Issue.12
, pp. 9400-9409
-
-
Kim, D.W.1
Kim, J.2
Gwack, Y.3
Han, J.H.4
Choe, J.5
-
42
-
-
0030741828
-
A point mutation abolishes the helicase but not the nucleoside triphosphatase activity of hepatitis C virus NS3 protein
-
HEILEK GM, PETERSON MG: A point mutation abolishes the helicase but not the nucleoside triphosphatase activity of hepatitis C virus NS3 protein. J. Virol. (1997) 71:6264-6266. (Pubitemid 27304977)
-
(1997)
Journal of Virology
, vol.71
, Issue.8
, pp. 6264-6266
-
-
Heilek, G.M.1
Peterson, M.G.2
-
43
-
-
0030979410
-
Structure of the hepatitisCvirusRNAhelicase domain
-
YA ON,HESSON T,CABLE Met al.: Structure of the hepatitisCvirusRNAhelicase domain. Nature Struct. Biol. (1997) 4:463-467.
-
(1997)
Nature Struct. Biol
, vol.4
, pp. 463-467
-
-
On, Y.A.1
Hesson, T.2
Cable, M.3
-
44
-
-
0032518490
-
Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: The crystal structure provides insights into the mode of unwinding
-
KIM JL, MORGENSTERN KA, GRIFFITH JP et al.: Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding. Structure (1998) 6:89-100. (Pubitemid 28084402)
-
(1998)
Structure
, vol.6
, Issue.1
, pp. 89-100
-
-
Kim, J.L.1
Morgenstern, K.A.2
Griffith, J.P.3
Dwyer, M.D.4
Thomson, J.A.5
Murcko, M.A.6
Lin, C.7
Caron, P.R.8
-
45
-
-
0032510963
-
Crystal structure of RNA helicase from genotype 1b hepatitis C virus
-
CHO H-S, HA N-C, KANG L-W et al.: Crystal structure of RNA helicase from genotype 1b hepatitis C virus. J. Biol. Chem. (1998) 273:15045-15052.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 15045-15052
-
-
Cho, H.-S.1
Ha, N.-C.2
Kang, L.-W.3
-
46
-
-
0029074519
-
A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro
-
LIN C, THOMSON JA, RICE CM: A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro. J. Virol. (1995) 69:4373-4380.
-
(1995)
J. Virol
, vol.69
, pp. 4373-4380
-
-
Lin, C.1
Thomson, J.A.2
Rice, C.M.3
-
47
-
-
0028831056
-
Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing
-
TANJI Y, HIJIKATA M, SATOH S et al.: Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing. J. Virol. (1995) 69:1575-1581.
-
(1995)
J. Virol
, vol.69
, pp. 1575-1581
-
-
Tanji, Y.1
Hijikata, M.2
Satoh, S.3
-
48
-
-
0027515735
-
Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus
-
DOI 10.1073/pnas.90.22.10773
-
HIJIKATA M, MIZUSHIMA H, TANJI Y et al.: Proteolytic processing and membrane association of putative nonstructural proteins of hepatitisCvirus. Proc. Natl. Acad. Sci. USA (1993) 90:10773-10777. (Pubitemid 23347125)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.22
, pp. 10773-10777
-
-
Hijikata, M.1
Mizushima, H.2
Tanji, Y.3
Komoda, Y.4
Hirowatari, Y.5
Akagi, T.6
Kato, N.7
Kimura, K.8
Shimotohno, K.9
-
50
-
-
0028978937
-
Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A
-
TANJI Y, KANEKO T, SATOH S, SHIMOTOHNO K: Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A. J. Virol. (1995) 69:3980-3986.
-
(1995)
J. Virol
, vol.69
, pp. 3980-3986
-
-
Tanji, Y.1
Kaneko, T.2
Satoh, S.3
Shimotohno, K.4
-
51
-
-
0031780867
-
The NS5A/NS5 proteins of viruses from three genera of the family Flaviviridae are phosphorylated by associated serine/threonine kinases
-
REED KE, GORBALENYA AE, RICE CM: The NS5A/NS5 proteins of viruses from three genera of the family Flaviviridae are phosphorylated by associated serine/threonine kinases. J. Virol. (1998) 72:6199-6206. (Pubitemid 28283416)
-
(1998)
Journal of Virology
, vol.72
, Issue.7
, pp. 6199-6206
-
-
Reed, K.E.1
Gorbalenya, A.E.2
Rice, C.M.3
-
52
-
-
0030879817
-
Hepatitis C virus nonstructural region 5A protein is a potent transcriptional activator
-
KATO N,LAN K-H, ONO-NITA SK et al.: HepatitisCvirus nonstructural region 5A protein is a potent transcriptional activator. J. Virol. (1997) 71:8856-8859. (Pubitemid 27446471)
-
(1997)
Journal of Virology
, vol.71
, Issue.11
, pp. 8856-8859
-
-
Kato, N.1
Lan, K.-H.2
Ono-Nita, S.K.3
Shiratori, Y.4
Omata, M.5
-
53
-
-
0343924357
-
Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein
-
DOI 10.1006/viro.1997.8493
-
GALE MJ, Jr., KORTH MJ, TANG NM et al.: Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein. Virology (1997) 230:217-227. (Pubitemid 27211852)
-
(1997)
Virology
, vol.230
, Issue.2
, pp. 217-227
-
-
Gale Jr., M.J.1
Korth, M.J.2
Tang, N.M.3
Tan, S.-L.4
Hopkins, D.A.5
Dever, T.E.6
Polyak, S.J.7
Gretch, D.R.8
Katze, M.G.9
-
54
-
-
0024784519
-
Identification of four conserved motifs among the RNA-dependent polymerase encoding elements
-
POCH O, SAUVAGER I, DELARUE M, TORDO N: Identification of four conserved motifs among the RNA-dependent polymerase encoding elements. EMBO J. (1989) 8:3867-3874. (Pubitemid 20016069)
-
(1989)
EMBO Journal
, vol.8
, Issue.12
, pp. 3867-3874
-
-
Poch, O.1
Sauvaget, I.2
Delarue, M.3
Tordo, N.4
-
55
-
-
0030051777
-
Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus
-
BEHRENS S-K, TOMEI L, DE FRANCESCO R: Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus. EMBO J. (1996) 15:12-22. (Pubitemid 26020384)
-
(1996)
EMBO Journal
, vol.15
, Issue.1
, pp. 12-22
-
-
Behrens, S.-E.1
Tomei, L.2
De Francesco, R.3
-
56
-
-
1842289764
-
Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity
-
LOHMAN NV, KORNER F, HERIAN U, BARTENSCHLAGER R: Biochemical properties of hepatitisCvirus NS5B RNA-dependentRNApolymerase and identification of amino acid sequence motifs essential for enzymatic activity. J. Virol. (1997) 71:8416-8428. (Pubitemid 27446422)
-
(1997)
Journal of Virology
, vol.71
, Issue.11
, pp. 8416-8428
-
-
Lohmann, V.1
Korner, F.2
Herian, U.3
Bartenschlager, R.4
-
57
-
-
0031555848
-
Expression, purification, and partial characterization of HCV RNA polymerase
-
DOI 10.1006/bbrc.1997.6249
-
YUAN Z-H, KUMAR U, THOMAS HC et al.: Expression, purification, and partial characterization of HCV RNA polymerase. Biochem. Biophys. Res. Commun. (1997) 232:231-235. (Pubitemid 27211954)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.232
, Issue.1
, pp. 231-235
-
-
Yuan, Z.-H.1
Kumar, U.2
Thomas, H.C.3
Wen, Y.-M.4
Monjardino, J.5
-
58
-
-
0032546963
-
RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the C-terminal region
-
DOI 10.1074/jbc.273.25.15479
-
YAMASHITA T, KANEKO S, SHIROTA Y et al.: RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the C-terminal region. J. Biol. Chem. (1998) 273:15479-15486. (Pubitemid 28298156)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.25
, pp. 15479-15486
-
-
Yamashita, T.1
Kaneko, S.2
Shirota, Y.3
Qin, W.4
Nomura, T.5
Kobayashi, K.6
Murakami, S.7
-
59
-
-
0031579246
-
Hepatitis C virus NS5B protein is a membrane-associated phosphoprotein with a predominantly perinuclear localization
-
DOI 10.1006/viro.1996.8357
-
HWANG SB, PARK K-J, KIM Y-S et al.: Hepatitis C virus NS5B protein is a membrane-associated phosphoprotein with a predominantly perinuclear localization. Virology (1997) 227:439-446. (Pubitemid 27241037)
-
(1997)
Virology
, vol.227
, Issue.2
, pp. 439-446
-
-
Hwang, S.B.1
Park, K.-J.2
Kim, Y.-S.3
Sung, Y.C.4
Lai, M.M.C.5
-
60
-
-
0030777974
-
Novel hepatitis C virus protease inhibitors: 2,4,6-trihydroxy,3-nitro- benzamide derivatives
-
SUDO K, MATSUMOTO Y, MATSUSHIMA M et al.: Novel hepatitis C virus protease inhibitors: 2,4,6-trihydroxy,3-nitro-benzamide derivatives. Antiviral Chem. Chemother. (1997) 8:541-544. (Pubitemid 27504719)
-
(1997)
Antiviral Chemistry and Chemotherapy
, vol.8
, Issue.6
, pp. 541-544
-
-
Sudo, K.1
Matsumoto, Y.2
Matsushima, M.3
Konno, K.4
Shimotohno, K.5
Shigeta, S.6
Yokota, T.7
-
61
-
-
0031954546
-
Novel hepatitis C virus protease inhibitors: 2,4,6-trihydroxy,3-nitro- benzamide derivatives
-
SUDO K, MATSUMOTO Y, MATSUSHIMA M et al.: Novel hepatitis C virus protease inhibitors: 2,4,6-trihydroxy,3-nitro-benzamide derivatives. Antiviral Chem. Chemother. (1998) 9:186.
-
(1998)
Antiviral Chem. Chemother
, vol.9
, pp. 186
-
-
Sudo, K.1
Matsumoto, Y.2
Matsushima, M.3
-
62
-
-
0031577565
-
Novel hepatitis C virus protease inhibitors: Thiazolidine derivatives
-
DOI 10.1006/bbrc.1997.7358
-
SUDO K, MATSUMOTO Y, MATSUSHIMA M et al.: Novel hepatitis C virus protease inhibitors: thiazolidine derivatives. Biochem. Biophys. Res. Commun. (1997) 238:643-647. (Pubitemid 27464443)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.238
, Issue.2
, pp. 643-647
-
-
Sudo, K.1
Matsumoto, Y.2
Matsushima, M.3
Fujiwara, M.4
Konno, K.5
Shimotohno, K.6
Shigeta, S.7
Yokota, T.8
-
63
-
-
0032536094
-
Non-peptide inhibitors of HCV serine proteinase
-
DOI 10.1016/S0014-5793(97)01566-4, PII S0014579397015664
-
KAKIUCHI N, KOMODA Y, KOMODA K et al.: Non-peptide inhibitors of HCV serine proteinase. FEBS Lett. (1998) 421:217-220. (Pubitemid 28045757)
-
(1998)
FEBS Letters
, vol.421
, Issue.3
, pp. 217-220
-
-
Kakiuchi, N.1
Komoda, Y.2
Komoda, K.3
Takeshita, N.4
Okada, S.5
Tani, T.6
Shimotohno, K.7
-
64
-
-
0028942494
-
NS3-4A of hepatitis C virus is a chymotrypsin-like protease
-
HAHM B, HAN DS, BACK SH et al.: NS3-4A of hepatitis C virus is a chymotrypsin-like protease. J. Virol. (1995) 69:2534-2539.
-
(1995)
J. Virol
, vol.69
, pp. 2534-2539
-
-
Hahm, B.1
Han, D.S.2
Back, S.H.3
-
65
-
-
0038343796
-
Product inhibition of the hepatitis C virus NS3 protease
-
DOI 10.1021/bi980313v
-
STEINKUHLER C, BIASIOL G, BRUNETTI M et al.: Product inhibition of the hepatitis C virus NS3 protease. Biochemistry (1998) 37:8899-8905. (Pubitemid 28299658)
-
(1998)
Biochemistry
, vol.37
, Issue.25
, pp. 8899-8905
-
-
Steinkuhler, C.1
Biasiol, G.2
Brunetti, M.3
Urbani, A.4
Koch, U.5
Cortese, R.6
Pessi, A.7
De Francesco, R.8
-
66
-
-
0032493405
-
Peptide-based inhibitors of the hepatitis C virus serine protease
-
DOI 10.1016/S0960-894X(98)00299-6, PII S0960894X98002996
-
LLINAS-BRUNET M, BAILEY M, FAZAL G et al.: Peptide-based inhibitors of the hepatitis C virus serine protease. Bioorg. Med. Chem. Lett. (1998) 8:1713-1718. (Pubitemid 28341617)
-
(1998)
Bioorganic and Medicinal Chemistry Letters
, vol.8
, Issue.13
, pp. 1713-1718
-
-
Llinas-Brunet, M.1
Bailey, M.2
Fazal, G.3
Goulet, S.4
Halmos, T.5
Laplante, S.6
Maurice, R.7
Poirier, M.8
Poupart, M.-A.9
Thibeault, D.10
Wernic, D.11
Lamarre, D.12
-
67
-
-
0032560602
-
Potent peptide inhibitors of human hepatitis C virus NS3 protease are obtained by optimizing the cleavage products
-
DOI 10.1021/bi980314n
-
INGALLINELLA P, ALTAMURA S, BIANCHI E et al.: Potent peptide inhibitors of human hepatitis C virus NS3 protease are obtained by optimizing the cleavage products. Biochemistry (1998) 37:8906-8914. (Pubitemid 28299659)
-
(1998)
Biochemistry
, vol.37
, Issue.25
, pp. 8906-8914
-
-
Ingallinella, P.1
Altamura, S.2
Bianchi, E.3
Taliani, M.4
Ingenito, R.5
Cortese, R.6
De Francesco, R.7
Steinkuhler, C.8
Pessi, A.9
-
68
-
-
0030719462
-
Isolation of RNA aptamers specific to the NS3 protein of hepatitis C virus from a pool of completely random RNA
-
DOI 10.1006/viro.1997.8773
-
KUMAR PKR,MACHIDA K, URVIL PT et al.: Isolation ofRNAaptamers specific to the NS3 protein of hepatitis C virus from a pool of completely random RNA. Virology (1997) 237:270-282. (Pubitemid 27489266)
-
(1997)
Virology
, vol.237
, Issue.2
, pp. 270-282
-
-
Kumar, P.K.R.1
Machida, K.2
Urvil, P.T.3
Kakiuchi, N.4
Vishnuvardhan, D.5
Shimotohno, K.6
Taira, K.7
Nishikawa, S.8
-
69
-
-
0030844452
-
Selection of RNA aptamers that bind specifically to the NS3 protease of hepatitis C virus
-
URVIL P, KAPIUCHI N,ZHOUD-Met al.: Selection ofRNAaptamers that bind specifically to the NS3 protease of hepatitis C virus. Eur. J. Biochem. (1997) 248:130-138. (Pubitemid 27356980)
-
(1997)
European Journal of Biochemistry
, vol.248
, Issue.1
, pp. 130-138
-
-
Urvil, P.T.1
Kakiuchi, N.2
Zhou, D.-M.3
Shimotohno, K.4
Kumar, P.K.R.5
Nishikawa, S.6
-
70
-
-
0030796292
-
Characterization of engineered hepatitis C virus NS3 protease inhibitors affinity selected from human pancreatic secretory trypsin inhibitor and minibody repertoires
-
DIMASSI N,MARTIN F, VOLPARI Cet al.: Characterization of engineered hepatitisCvirus NS3 protease: inhibitors selected from human pancreatic secretory trypsin inhibitor and minibody repertoire. J. Virol. (1997) 71:7461-7469. (Pubitemid 27391686)
-
(1997)
Journal of Virology
, vol.71
, Issue.10
, pp. 7461-7469
-
-
Dimasi, N.1
Martin, F.2
Volpari, C.3
Brunetti, M.4
Biasiol, G.5
Altamura, S.6
Cortese, R.7
De Francesco, R.8
Steinkuhler, C.9
Sollazzo, M.10
-
71
-
-
0032544214
-
Design of selective eglin inhibitors of HCV NS3 proteinase
-
DOI 10.1021/bi980283w
-
MARTIN F, DIMASI N, VOLPARI C et al.: Design of selective Eglin inhibitors of HCV NS3 proteinase. Biochemistry (1998) 37:11459-11468. (Pubitemid 28388187)
-
(1998)
Biochemistry
, vol.37
, Issue.33
, pp. 11459-11468
-
-
Martin, F.1
Dimasi, N.2
Volpari, C.3
Perrera, C.4
Di Marco, S.5
Brunetti, M.6
Steinkuhler, C.7
De Francesco, R.8
Sollazzo, M.9
-
72
-
-
0027199917
-
Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes
-
SUZICH JA, TAMURA JK, PALMER-HILL F et al.: Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related Pestivirus and Flavivirus enzymes. J. Virol. (1993) 67:6152-6158. (Pubitemid 23277527)
-
(1993)
Journal of Virology
, vol.67
, Issue.10
, pp. 6152-6158
-
-
Suzich, J.A.1
Tamura, J.K.2
Palmer-Hill, F.3
Warrener, P.4
Grakoui, A.5
Rice, C.M.6
Feinstone, S.M.7
Collett, M.S.8
-
73
-
-
0029970903
-
The helicase activity associated with hepatitis C virus nonstructural protein 3 (NS3)
-
TAI C-L, CHI W-K, CHEN D-S, HWANG L-H: The helicase activity associated with hepatitis C virus non structural protein 3 (NS3). J. Virol. (1996) 70:8477-8484. (Pubitemid 26378425)
-
(1996)
Journal of Virology
, vol.70
, Issue.12
, pp. 8477-8484
-
-
Tai, C.-L.1
Chi, W.-K.2
Chen, D.-S.3
Hwang, L.-H.4
-
74
-
-
0028800155
-
Poly(U) binding activity of hepatitis C virus NS3 protein, a putative RNA helicase
-
KANAI A, KYOKO T, MICHINORI K: Poly(U) binding activity of hepatitis C virus NS3 protein, a putative RNA helicase. FEBS Lett. (1995) 376:221-224.
-
(1995)
FEBS Lett
, vol.376
, pp. 221-224
-
-
Kanai, A.1
Kyoko, T.2
Michinori, K.3
-
75
-
-
79961065654
-
The structure of HCV RNA helicase and its relevance to the design of new anti-HCV drugs
-
(In press)
-
LE HV, YAO NH, MURGOLO N, WEBER PC: The structure of HCV RNA helicase and its relevance to the design of new anti-HCV drugs. Hepatologia Clinica (In press).
-
Hepatologia Clinica
-
-
Hv, L.E.1
Yao, N.H.2
Murgolo, N.3
Weber, P.C.4
-
76
-
-
0031911760
-
Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases
-
KOROLEV S, YAO N, LOHMAN TM, WEBER PC, WAKSMAN G: Comparisons between the structures ofHCVand Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases. Protein Sci. (1998) 7:605-610. (Pubitemid 28130882)
-
(1998)
Protein Science
, vol.7
, Issue.3
, pp. 605-610
-
-
Korolev, S.1
Yao, N.2
Lohman, T.M.3
Weber, P.C.4
Waksman, G.5
-
77
-
-
0031571638
-
Structure of the RNA-dependentRNApolymerase of poliovirus
-
HANSEN JL,LONG AM,SCHULTZ SC: Structure of the RNA-dependentRNApolymerase of poliovirus. Structure (1997) 5:1109-1122.
-
(1997)
Structure
, vol.5
, pp. 1109-1122
-
-
Hansen, J.L.1
Long, A.M.2
Schultz, S.C.3
-
78
-
-
0027153210
-
Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism
-
WANG C,SARNOW P, SIDDIQUI A: Translation of hepatitisCvirusRNAin cultured cells is mediated by an internal ribosome-binding mechanism. J. Virol. (1998) 67:3338-3344. (Pubitemid 23143708)
-
(1993)
Journal of Virology
, vol.67
, Issue.6
, pp. 3338-3344
-
-
Wang, C.1
Sarnow, P.2
Siddiqui, A.3
-
79
-
-
0031779191
-
A small yeast RNA blocks hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation and inhibits replication of a chimeric poliovirus under translational control of the HCV IRES element
-
DAS S, OTT M, YAMANE A et al.: A small yeast RNA blocks hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation and inhibits replication of a chimeric poliovirus under translational control of the HCV IRES element. J. Virol. (1998) 72:5638-5647. (Pubitemid 28283348)
-
(1998)
Journal of Virology
, vol.72
, Issue.7
, pp. 5638-5647
-
-
Das, S.1
Ott, M.2
Yamane, A.3
Tsai, W.4
Gromeier, M.5
Lahser, F.6
Gupta, S.7
Dasgupta, A.8
-
80
-
-
0030589627
-
Zinc mediated dimer of human interferon-α(2b) revealed by X-ray crystallography
-
RADHAKRISHNAN R, WALTER LJ, HRUZA A et al.: Zinc mediated dimer of human interferon-a2b revealed by X-ray crystallography. Structure (1996) 4:1453-1463. (Pubitemid 27050278)
-
(1996)
Structure
, vol.4
, Issue.12
, pp. 1453-1463
-
-
Radhakrishnan, R.1
Walter, L.J.2
Hruza, A.3
Reichert, P.4
Trotta, P.P.5
Nagabhushan, T.L.6
Walter, M.R.7
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