Microfluidics: Basic issues, applications, and challenges

AIChE Journal

Volumn 47, Issue 6, 2001, Pages 1250-1254

  Stone, H A ^a   Kim, S ^b  

^a HARVARD UNIVERSITY   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOPOLYMER; DNA; POLYMER; PROTEIN; WATER;

FLUIDICS;

AQUEOUS SOLUTION; CHEMICAL ENGINEERING; COMBINATORIAL CHEMISTRY; DEVICE; DIFFUSION; DIPOLE; DISPERSION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG INDUSTRY; DYNAMICS; ELECTRIC FIELD; ELECTRICAL EQUIPMENT; ELECTROOSMOSIS; ELECTROPHORESIS; FLOW KINETICS; FLOW RATE; FLUID FLOW; FLUID TRANSPORT; FORCE; FRICTION; GAS; GEOMETRY; HYDRODYNAMICS; MEDICAL RESEARCH; MICROANALYSIS; NANOPARTICLE; NANOTECHNOLOGY; NON INVASIVE MEASUREMENT; PARTICLE SIZE; PHYSICS; PRESSURE; REVIEW; SCREENING; SEPARATION TECHNIQUE; SOLID; SURFACE PROPERTY; TENSION; WETTABILITY;

EID: 0000032056     PISSN: 00011541     EISSN: None     Source Type: Journal    
DOI: 10.1002/aic.690470602     Document Type: Review

References (28)

1. Arkilic, E. B., M. A. Schmidt, and K. S. Breuer, "Gaseous Slip Flow in Long Microchannels," J. Microelectromech. Sys., 6, 167 (1997).
2. Babcock, H. P., D. E. Smith, J. S. Hur, E. S. G. Shaqfeh, and S. Chu, "Relating the Microscopic and Macroscopic Response of a Polymeric Fluid in a Shearing Flow," Phys. Rev. Lett., 85, 2018 (2000).
3. Chang, H.-C., "Bubble/Drop Transport in Micro-Channels," CRC MEMS Handbook, M. Gad-el-Hak, ed. (2001).
4. Darhuber, A. A., S. M. Troian, J. M. Davis, and S. M. Miller, "Selective Dip-Coating of Chemically Micropatterned Surfaces," J. Appl. Phys., 88, 5119 (2000).
5. Duke, T. A. J., and R. H. Austin, "Microfabricated Sieve for the Continuous Sorting of Macromolecules," Phys. Rev. Lett., 80, 1552 (1998).
6. Gad-el-Hak, M., "The Fluid Mechanics of Microdevices-The Freeman Scholar Lecture," J. Fluids Engineering, 121, 5 (1999).
7. Gallardo, B. S., V. K. Gupta, F. D. Eagerton, L. I. Jong, V. S. Craig, R. R. Shah, and N. L. Abbott, "Electrochemical Principles for Active Control of Liquids on Submillimeter Scales," Science, 283, 57 (1999).
8. Happel, J., and H. Brenner, Low Reynolds Number Hydrodynamics, Martinus Nijhoff (1983).
9. Ho, C.-M., "Fluidics: The Link between Micro and Nano Sciences and Technologies," 14th IEEE Intl. Conf. on MEMS 2001, Interlaken, Switzerland, 375 (2001).
10. Ho, C.-M., and Y.-C. Tai, "Micro-Electro-Mechanical Systems (MEMS) and Fluid Flows," Ann. Rev. Fluid Mech., 30, 579 (1998).
11. Huang, Y., X. Duan, Q. Wei, and C. M. Lieber, "Directed Assembly of One-Dimensional Nanostructures into Functional Networks," Science, 291, 630 (2001).
12. Ismagilov, R. F., A. D. Stroock, P. J. A. Kenis, G. Whitesides, and H. A. Stone, "Experimental and Theoretical Scaling Laws for Transverse Diffusive Broadening in Two-Phase Laminar Flow in Microchannels," Appl. Phys. Lett., 76, 2376 (2000).
13. Jain, K. K., "Biochips and Microarrays: Technology and Commercial Potential," Pharmaceutical Industry Report, published by Informa Pharmaceuticals (2000).
14. Jensen, K. F., "Microchemical Systems: Status, Challenges, and Opportunities," AIChE J., 45, 2051 (1999).
15. Kenis, R. J. A., R. F. Ismagilov, and G. M. Whitesides, "Microfabrication Inside Capillaries Using Multiphase Laminar Flow Patterning," Science, 285, 83 (1999).
16. Kim, S., and S. J. Karrila, Microhydrodynamics, Butterworth-Heinemann (1991).
17. Langer, R., "Biomaterials: Status, Challenges, and Perspectives," AIChE J., 46, 1286 (2000).
18. Liu, R. H., M. A. Stremler, K. V. Sharp, M. G. Olsen, J. G. Santiago, R. J. Adrian, H. Aref, and D. J. Beebe, "Passive Mixing in a Three -Dimensional Serpentine Microchannel," J. Microelectromech. Sys., 9, 190 (2000).
19. McDonald, J. C., D. C. Duffy, J. R. Anderson, D. T. Chiu, H. Wu, O. J. A. Schueller, and G. M. Whitesides, "Fabrication of Microfluidic Systems in Poly (dimethylsiloxane)," Electrophoresis, 21, 27 (2000).
20. Ottino, J. M., The Kinematics of Mixing, Cambridge University Press (1989).
21. Pit, R., H. Hervet, and L. Léger, "Direct Experimental Evidence of Slip in Hexadecane: Solid Interfaces," Phys. Rev. Lett., 85, 980 (2000).
22. Quake, S. R., and A. Scherer, "From Micro- to Nanofabrication with Soft Materials," Science, 290, 1536 (2000).
23. Russel, W. B., D. A. Saville, and W. R. Schowalter, Colloidal Dispersions, Cambridge University Press (1992).
24. Sharp, K. V., R. J. Adrian, J. G. Santiago, and J. I. Molho, "Liquid Flow in Microchannels," CRC MEMS Handbook, M. Gad-elHak, ed., in press (2001).
25. Squires, T. M., and M. P. Brenner, "Like-Charge Attraction and Hydrodynamic Interaction," Phys. Rev. Lett., 85, 4976 (2001).
26. Takayama, S., E. Ostuni, X. Qian, J. C. McDonald, X. Jiang, P. LeDuc, M. H. Wu, D. E. Ingher, and G. M. Whitesides, "Topographical Micropatterning of Poly(dimethylsiloxane) Using Laminar Flows of Liquids in Capillaries," Advanced Matls., in press (2001).
27. Whitesides, G. M., and A. D. Stroock, "Microfluidics," Physics Today, in press (2001).
28. Zhao, B., J. S. Moore, and D. J. Beebe, "Surface-Directed Liquid Flow Inside Microchannels," Science, 291, 1023 (2001).