4-Hydroxynonenal inhibits cell proliferation and alters differentiation pathways in human fetal liver hematopoietic stem cells

Biochemical Pharmacology

Volumn 69, Issue 1, 2005, Pages 105-112

  Moneypenny, Craig G ^a   Gallagher, Evan P ^a  

^a School of Public Health and Community Medicine   (United States)

Author keywords

4 Hydroxynonenal; Apoptosis; Differentiation; Human fetal hematopoietic stem cells

Indexed keywords

4 HYDROXYNONENAL; ANTIMITOTIC AGENT;

APOPTOSIS; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL POPULATION; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; FETUS; FETUS LIVER; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; STEADY STATE; UTERUS;

ALDEHYDES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; HEMATOPOIETIC STEM CELLS; HUMANS; LIVER; SIGNAL TRANSDUCTION;

EID: 9944258569     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.09.001     Document Type: Article

References (44)

1. M.U. Dianzani 4-Hydroxynonenal from pathology to physiology Mol Aspects Med 24 2003 263 272
2. K. Uchida 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress Prog Lipid Res 42 2003 318 343
3. H. Esterbauer, R.J. Schaur, and H. Zollner Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes Free Radic Biol Med 11 1991 81 128
4. M. Poot, A. Verkerk, J.F. Koster, H. Esterbauer, and J.F. Jongkind Reversible inhibition of DNA and protein synthesis by cumene hydroperoxide and 4-hydroxy-nonenal Mech Ageing Dev 43 1988 1 9
5. S. Hauptlorenz, H. Esterbauer, W. Moll, R. Pumpel, E. Schauenstein, and B. Puschendorf Effects of the lipid peroxidation product 4-hydroxynonenal and related aldehydes on proliferation and viability of cultured Ehrlich ascites tumor cells Biochem Pharmacol 34 1985 3803 3809
6. J.J. Chen, and B.P. Yu Alterations in mitochondrial membrane fluidity by lipid peroxidation products Free Radic Biol Med 17 1994 411 418
7. D. Zanetti, G. Poli, B. Vizio, B. Zingaro, E. Chiarpotto, and F. Biasi 4-Hydroxynonenal and transforming growth factor-beta1 expression in colon cancer Mol Aspects Med 24 2003 273 280
8. K. Okamoto, S. Toyokuni, K. Uchida, O. Ogawa, J. Takenewa, and Y. Kakehi Formation of 8-hydroxy-2′-deoxyguanosine and 4-hydroxy-2-nonenal-modified proteins in human renal-cell carcinoma Int J Cancer 58 1994 825 829
9. W. Palinski, S. Yla-Herttuala, M.E. Rosenfeld, S.W. Butler, S.A. Socher, and S. Parthasarathy Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein Arteriosclerosis 10 1990 325 335
10. W.R. Markesbery, and M.A. Lovell 4-Hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease Neurobiol Aging 19 1998 33 36
11. A. Yoritaka, N. Hattori, K. Uchida, M. Tanaka, E.R. Stadtman, and Y. Mizuno Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease Proc Natl Acad Sci USA 93 1996 2696 2701
12. S. Morikawa, O. Kurauchi, M. Tanaka, M. Yoneda, K. Uchida, and A. Itakura Increased mitochondrial damage by lipid peroxidation in trophoblast cells of preeclamptic placentas Biochem Mol Biol Int 41 1997 767 775
13. T. Ogihara, K. Hirano, T. Morinobu, H.S. Kim, M. Hiroi, and H. Ogihara Raised concentrations of aldehyde lipid peroxidation products in premature infants with chronic lung disease Arch Dis Child Fetal Neonatal Ed 80 1999 F21 F25
14. H. Schmidt, T. Grune, R. Muller, W.G. Siems, and R.R. Wauer Increased levels of lipid peroxidation products malondialdehyde and 4-hydroxynonenal after perinatal hypoxia Pediatr Res 40 1996 15 20
15. J.J. Chen, S. Schenker, and G.I. Henderson 4-Hydroxynonenal levels are enhanced in fetal liver mitochondria by in utero ethanol exposure Hepatology 25 1997 142 147
16. J.J. Chen, S. Schenker, and G.I. Henderson 4-Hydroxynonenal detoxification by mitochondrial glutathione S-transferase is compromised by short-term ethanol consumption in rats Alcohol Clin Exp Res 26 2002 1252 1258
17. S.J. Morrison, and I.L. Weissman Heterogeneity of hematopoietic stem cells: implications for clinical applications Proc Assoc Am Physicians 107 1995 187 194
18. R.S. Robinson, and L.L. Seelig Jr. Effects of maternal ethanol consumption on hematopoietic cells in the rat fetal liver Alcohol 28 2002 151 156
19. R.R. Watson, R.H. Prabhala, E. Abril, and T.L. Smith Changes in lymphocyte subsets and macrophage functions from high, short-term dietary ethanol in C57/BL6 mice Life Sci 43 1988 865 870
20. R.R. MacGregor Alcohol and immune defense J Am Med Assoc 25 1986 1474 1479
21. J.L. Gardner, A.M. Doi, R.T. Pham, C.M. Huisden, and E.P. Gallagher Ontogenic differences in human liver 4-hydroxynonenal detoxification are associated with in vitro injury to fetal hematopoietic stem cells Toxicol Appl Pharmacol 191 2003 95 106
22. M.K. Warren, W.L. Rose, L.D. Beall, and J. Cone CD34+ cell expansion and expression of lineage markers during liquid culture of human progenitor cells Stem Cells 13 1995 167 174
23. S.A. Ahmed, R.M. Gogal Jr., and J.E. Walsh A new rapid and simple non-radioactive assay to monitor and determine the proliferation of lymphocytes: an alternative to [3H] thymidine incorporation assay J Immunol Methods 170 1994 211 224
24. G. Barrera, Di, C. Mauro, R. Muraca, D. Ferrero, and M.G. Farace Induction of differentiation in human HL-60 cells by 4-hydroxynonenal, a product of lipid peroxidation Exp Cell Res 197 1991 148 152
25. G. Barrera, R. Muraca, S. Pizzimente, A. Serra, C. Rosso, and G. Saglio Inhibition of c-myc expression induced by 4-hydroxynonenal, a product of lipid peroxidation, in the HL-60 human leukemic cell Lline Biochem Biophys Res Commun 203 1994 553 561
26. X. Li, and A. Darzynkiewicz Labeling DNA strand breaks with BrdUTP detection of apoptosis and cell proliferation Cell Prolif 28 1995 571 579
27. M.O. Muench, M.T. Firpo, and M.A. Moore Bone marrow transplantation with interleukin-1 plus kit-ligand ex vivo expanded bone marrow accelerates hematopoietic reconstitution in mice without the loss of stem cell lineage and proliferative potential Blood 81 1993 3463 3473
28. H.J. Sutherland, P.M. Lansdorp, D.H. Henkelman, A.C. Eaves, and C.J. Eaves Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers Proc Natl Acad Sci USA 87 1990 3584 3588
29. S.J. Lu, F. Li, L. Vida, and G.R. Honig CD34CD38 Hematopoietic precursors derived from human embryonic stem cells exhibit an embryonic gene expression pattern Blood 103 2004 4134 4141
30. Y.Y. Ng, B. van Kessel, H.M. Lokhorst, M.R. Baert, C.M. van den Burg, and A.C. Bloem Gene-expression profiling of CD34+ cells from various hematopoietic stem-cell sources reveals functional differences in stem-cell activity J Leukoc Biol 75 2004 314 323
31. F. Shojaei, L. Gallacher, and M. Bhatia Differential gene expression of human stem progenitor cells derived from early stages of in utero human hematopoiesis Blood 103 2004 2530 2540
32. W. Siems, and T. Grune Intracellular metabolism of 4-hydroxynonenal Mol Aspects Med 24 2003 167 175
33. G. Barrera, S. Pizzimenti, S. Laurora, E. Moroni, B. Giglioni, and M.U. Dianzani 4-Hydroxynonenal affects pRb/E2F pathway in HL-60 human leukemic cells Biochem Biophys Res Commun 295 2002 267 275
34. B.P. Samprey, S. Korourian, M.J. Ronis, T.M. Badger, and D.R. Petersen Immunohistochemical characterization of hepatic malondialdehyde and 4-hydroxynonenal modified proteins during early stages of ethanol induced liver injury Alcohol Clin Exp Res 27 2003 1015 1022
35. J.Z. Cheng, R. Sharma, Y. Yang, S.S. Singhal, A. Sharma, and M.K. Saini Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress J Biol Chem 276 2001 41213 41223
36. D.M. Svinarich, J.A. DiCerbo, F.M. Zaher, F.D. Yelian, and B. Gonik Ethanol-induced expression of cytokines in a first-trimester trophoblast cell line Am J Obstet Gynecol 179 1998 470 475
37. K.L. Biber, K.M. Moscatello, D.C. Dempsey, R. Chervenak, and R.M. Wolcott Effects of in utero alcohol exposure on B-cell development in the murine fetal liver Alcohol Clin Exp Res 22 1998 1706 1712
38. N. Zarkovic 4-Hydroxynonenal as a bioactive marker of patho-physiological processes Mol Aspects Med 24 2003 281 291
39. G. Barrera, S. Pizzimenti, R. Muraca, G. Barbiero, G. Bonelli, and F.M. Baccino Effect of 4-hydroxynonenal on cell cycle progression and expression of differentiation-associated antigens in HL-60 cells Free Radic Biol Med 20 1996 455 462
40. L. Belov, P. Huang, N. Barber, S.P. Mulligan, and R.I. Christopherson Identification of repertoires of surface antigens on leukemias using an antibody microarray Proteomics 3 2003 2147 2154
41. G.I. Henderson, J.J. Chen, and S. Schenker Ethanol, oxidative stress, reactive aldehydes, and the fetus Front Biosci 4 1999 D541 D550
42. Y.C. Awasthi, R. Sharma, J.Z. Cheng, Y. Yang, A. Sharma, and S.S. Singhal Role of 4-hydroxynonenal in stress-mediated apoptosis signaling Mol Aspects Med 24 2003 219 230
43. J.P. Maciejewski, and A. Risitano Hematopoietic stem cells in aplastic anemia Arch Med Res 34 2003 520 527
44. C.M. McHale, and M.T. Smith Prenatal origin of chromosomal translocations in acute childhood leukemia: implications and future directions Am J Hematol 75 2004 254 257