4-Hydroxynonenal and transforming growth factor-β1 expression in colon cancer

Molecular Aspects of Medicine

Volumn 24, Issue 4-5, 2003, Pages 273-280

  Zanetti, D ^a   Poli, G ^a   Vizio, B ^a   Zingaro, B ^a   Chiarpotto, E ^a   Biasi, F ^a,b  

^a UNIVERSITY OF TURIN   (Italy)

^b CNR   (Italy)

Author keywords

4 Hydroxynonenal; AP 1; Apoptosis; CaCo 2; Colon cancer; JNK; Lipid peroxidation; MAPK; Oxidative stress; Smads; TGF 1 receptors; Transduction signals; Transforming growth factor 1

Indexed keywords

4 HYDROXYNONENAL; CYTOKINE; MITOGEN ACTIVATED PROTEIN KINASE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

APOPTOSIS; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN CACO 2; COLON CANCER; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; LIPID PEROXIDATION; SIGNAL TRANSDUCTION;

EID: 0043172456     PISSN: 00982997     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0098-2997(03)00022-0     Document Type: Conference Paper

References (21)

1. Baxter S.W., Choong D.Y., Eccles D.M., Campbell I.G. Transforming growth factor beta receptor 1 polyalanine polymorphism and exon 5 mutation analysis in breast and ovarian cancer. Cancer Epidemiol. Biomarkers Prev. 11:2002;211-214.
2. Cheeseman K.H. Mechanisms and effects of lipid peroxidation. Mol. Aspects Med. 14:1993;191-197.
3. Chiarpotto E., Scavazza A., Leonarduzzi G., Camandola S., Biasi F., Teggia P.M., Garavoglia M., Robecchi A., Roncari A., Poli G. Oxidative damage and transforming growth factor β1 expression in pretumoral and tumoral lesions of human intestine. Free Radic. Biol. Med. 5:1997;889-894.
4. de Caestecker M.P., Piek E., Roberts A.B. Role of transforming growth factor-β signaling in cancer. J. Natl. Cancer Inst. 92:2000;1388-1402.
5. De Nigris F., Franconi F., Maida I., Palumbo G., Anania V., Napoli C. Modulation by. α - and γ -tocopherol and oxidized low-density lipoprotein of apoptotic signaling in human coronary smooth muscle cells Biochem. Pharmacol. 59:2000;1477-1487.
6. Dianzani M.U. Lipid peroxidation and cancer. Crit. Rev. Oncol./Hematol. 15:1993;125-147.
7. Enomoto A., Esumi M., Yamashita K., Takagi K., Takano S., Iwai S. Abnormal nucleotide repeat sequence in the TGF-beta RII gene in hepatocellular carcinoma and in uninvolved liver tissue. J. Pathol. 195:2001;349-354.
8. Kakishita H., Hattori Y. Vascular smooth muscle cell activation and growth by 4-hydroxynonenal. Life Sci. 69:2001;689-697.
9. Kim J.H., Shariat S.F., Kim I.Y., Menesses-Diaz A., Tokunaga H., Wheeler T.M., Lerner S.P. Predictive value of expression of transforming growth factor-beta(1) and its receptors in transitional cell carcinoma of the urinary bladder. Cancer. 92:2001;1475-1483.
10. Kim W.S., Park C., Jung Y.S., Kim H.S., Han J., Park C.H., Kim K., Kim J., Shim Y.M., Park K. Reduced transforming growth factor-beta type II receptor (TGF-beta RII) expression in adenocarcinoma of the lung. Anticancer Res. 19:1999;301-306.
11. Leonarduzzi G., Scavazza A., Biasi F., Chiarpotto E., Camandola S., Vogl S., Dargel R., Poli G. The lipid peroxidation end product 4-hydroxy-2,3-nonenal up-regulates transforming growth factor β1 expression in the macrophage lineage: a link between oxidative injury and fibrosclerosis. FASEB J. 11:1997;851-857.
12. Massaguè J. TGF-β signal transduction. Annu. Rev. Biochem. 67:1998;753-791.
13. Matsushita M., Matsuzaki K., Date M., Watanabe T., Shibano K., Nakagawa T., Yanagitani S., Amoh Y., Takemoto H., Ogata N., Yamamoto C., Kubota Y., Seki T., Inokuchi H., Nishizawa M., Takada H., Sawamura T., Okamura A., Inoue K. Down-regulation of TGF-beta receptors in human colorectal cancer: implications for cancer development. Br. J. Cancer. 80:1999;194-205.
14. Parola M., Robino G., Marra F., Pinzani M., Bellomo G., Leonarduzzi G., Chiarugi G., Camandola S., Poli G., Waeg G., Gentilini P., Dianzani M.U. HNE interacts directly with JNK isoforms in human hepatic stellate cells. J. Clin. Invest. 102:1998;1942-1950.
15. Poli G., Parola M. Oxidative damage and fibrogenesis. Free Radic. Biol. Med. 22:1997;287-305.
16. Poli G. Pathogenesis of liver fibrosis: role of oxidative stress. Mol. Aspects Med. 21:2000;48-98.
17. Soh Y., Jeong K.-S., Lee I.J., Bae M.-A., Kim Y.-C., Song B.J. Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxynonenal-induced apoptosis of PC12 cells. Mol. Pharmacol. 58:2000;535-541.
18. Uchida K., Shiraishi M., Naito Y., Torii Y., Nakamura Y., Osawa T. Activation of stress signaling pathways by the end product of lipid peroxidation. J. Biol. Chem. 274:1999;2234-2242.
19. Verrecchia F., Vindevoghel L., Lechleider R.J., Uitto J., Roberts A.B., Mauviel A. Smad3/AP-1 interactions control transcriptional responses to TGF-β in a promoter-specific manner. Oncogene. 20:2001;3332-3340.
20. Xie W., Mertens J.C., Reiss D.J., Rimm D.L., Camp R.L., Haffty B.G., Reiss M. Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study. Cancer Res. 62:2002;497-505.
21. Zhang Y., Feng X.H., Derynck R. Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription. Nature. 394:1998;909-913.