Cyclophilin A functions as an endogenous inhibitor for membrane-bound guanylate cyclase-A

Hypertension

Volumn 44, Issue 6, 2004, Pages 963-968

  Chen, Zi Jiang ^a,b   Vetter, Michael ^a   Chang, Geen Dong ^c   Liu, Shiguo ^a   Che, Danian ^a   Ding, Yaxian ^a   Sung, Soo Kim ^d   Chang, Chung Ho ^a,e  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b SHANDONG UNIVERSITY   (China)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d Kyung Hee University   (South Korea)

^e Alzheimer Research Laboratory   (United States)

Author keywords

Cyclic GMP; Cyclosporin

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CYCLOPHILIN A; CYCLOSPORIN A; GUANYLATE CYCLASE; PROLINE;

ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ISOMERIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; STATISTICAL SIGNIFICANCE;

ANIMALS; ATRIAL NATRIURETIC FACTOR; CATALYTIC DOMAIN; CERCOPITHECUS AETHIOPS; COS CELLS; CYCLOPHILIN A; ENZYME ACTIVATION; GUANYLATE CYCLASE; LLC-PK1 CELLS; PEPTIDYLPROLYL ISOMERASE; PROLINE; RECEPTORS, ATRIAL NATRIURETIC FACTOR; SWINE; TRANSFECTION;

EID: 9644295548     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000145859.94894.23     Document Type: Article

References (33)

1. Borel JF. Mechanisms of action of cyclosporin A and rationale for use in nephritic syndrome. Clin Nephrol. 1991;35(suppl):S23-S30.
2. Jain A, Khanna A, Molmenti EP, Rishi N, Fung JJ. Immunosuppressive therapy. Surg Clin North Am. 1999;79:59-76.
3. Hamilton GS, Steiner JP. Immunophilins: beyond immunosuppression. J Med Chem. 1998;41:5119-5143.
4. Hunter T. Prolyl isomerases and nuclear function. Cell. 1998;92:141-143.
5. Andreeva L, Heads R, Green CJ. Cyclophilins and their possible role in the stress response. Int J Exp Pathol. 1999;80:305-315.
6. Bukrinsky MI. Cyclophilins: unexpected messengers in intercellular communications. Trends Immunol. 2002;23:323-325.
7. Steinmann B, Bruckner P, Superti-Furga A. Cyclosporin A slows collagen triple-helix formation in vivo: indirect evidence for a physiologic role of peptidyl-prolyl cis-trans isomerase. J Biol Chem. 1991;266:1299-1303.
8. Syed F, Rycyzyn MA, Westgate L, Clevenger CV. A novel and functional interaction between cyclophilin A and prolactin receptor. Endocrine. 2003;20:83-90.
9. Lee SP, Hwang YS, Kim YJ, Kwon KS, Kin HJ, Kim K, Chae HZ. Cyclophilin A binds to peroxiredoxins and activates its peroxidase activity. J Biol Chem. 2001;276:29826-29832.
10. Uittenbogaard A, Ying YS, Smart EJ. Characterization of a cytosolic heat-shock protein-caveolin chaperone complex. J Biol Chem. 1998;273:6525-6532.
11. Cande C, Vahsen N, Kouranti I, Schmitt E, Daugas E, Spahr C, Luban J, Kroemer RT, Giordanetto F, Garrido C, Penninger JM, Kroemer G. AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis. Oncogene. 2004;23:1-8.
12. Sapphire ACS, Bobardt MD, Gallay PA. Host cyclophilin A mediates HIV-1 attachment to target cells via heparans. EMBO J. 1999;18:6771-6785.
13. Pushkarsky T, Zybarth G, Dubrovsky L, Yurchenko V, Tang H, Guo H, Toole B, Sherry B, Bukrinsky M. CD147 faciliates HIV-1 infection by interacting with virus-associated cyclophilin A. Proc Natl Acad Sci U S A. 2001;98:6360-6365.
14. Saphire AC, Bobardt MD, Gallay PA. Trans-complementation rescue of cyclophilin A-deficient viruses reveals that the requirement for cyclophilin A in human immunodeficiency virus type 1 replication is independent of its isomerase activity. J Virol. 2002;76:2255-2262.
15. Ansari H, Greco G, Luban J. Cyclophilin A peptidyl-prolyl isomerase activity promotes Zpr1 nuclear export. Mol Cell Biol. 2002;22:6993-7003.
16. Yurchenko V, Zybarth G, O'Connor M, Dai WW, Franchin G, Hao T, Guo H, Hung HC, Toole B, Gallay P, Sherry B, Bukrinsky M. Active site residues of cyclophilin A are crucial for its signaling activity via CD147. J Biol Chem. 2002;277:22959-22965.
17. Bosco DA, Eisenmesser EZ, Pochapsky S, Sundquist WI, Kern D. Catalysis of cis/trans isomerization in native HIV-1 caspid by human cyclophilin A. Proc Natl Acad Sci U S A. 2002;99:5247-5252.
18. Xie J, Zhao J, Davis PB, Ma J. Conformation, independent of charge, in the R domain affects cystic fibrosis transmembrane conductance regulator channel openings. Biophys J. 2000;78:1293-1305.
19. Brazin KN, Mallis RJ, Fulton DB, Andreotti AH. Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A. Proc Natl Acad Sci U S A. 2002;99:1899-1904.
20. Cui Y, Mirkia K, Florence Fu YH, Zhu L, Yokoyama KK, Chiu R. Interaction of the retinoblastoma gene product, RB, with cyclophilin A negatively affects cyclosporin-inhibited NFAT signaling. J Cell Biochem. 2002;86:630-641.
21. Jin ZG, Melarago MG, Liao DF, Yan C, Haendeler J, Suh YA, Lambeth JD, Berk BC. Cyclophilin A is a secreted growth factor induced by oxidative stress. Circ Res. 2000;87:789-796.
22. Garbers DL, Dubois SK. The molecular basis of hypertension. Annu Rev Biochem. 1999;68:127-155.
23. Kuhn M. Structure, regulation, and function of mammalian membrane guanylate cyclase receptors, with a focus on guanylate cyclase-A. Circ Res. 2003;93:700-709.
24. Chinkers M, Garbers DL. The protein kinase domain of the ANP receptor is required for signaling. Science. 1990;245:1392-1394.
25. Koller KJ, DeSauvage EJ, Lowe DG, Goeddel DV. Conservation of the kinase-like regulatory domain is essential for activation of the natriuretic peptide receptor guanylyl cyclase. Mol Cell Biol. 1992;12:2581-2590.
26. Chen ZJ, Song DL, Miao Z, Chang CH. Proteolytic activation of membrane-bound guanylate cyclase. Biochem Pharmacol. 2001;61:915-920.
27. Chen ZJ, Miao ZH, Vetter, M, Dulin N, Liu S, Che D, Hughes B, Murad F, Douglas J, Chang CH. Molecular cloning of a regulatory protein for membrane-bound guanylate cyclase GC-A. Biochem Biophys Res Commun,. 2000;278:106-111.
28. Miao ZH, Song DL, Douglas G, Chang CH. Mutational inactivation of the catalytic domain of guanylate cyclase-A receptor. Hypertension. 1995;25:694-698.
29. Vetter M, Chen ZJ, Chang GD, Che D, Liu S, Chang CH. Cyclosporin A disrupts bradykinin signaling through superoxide. Hypertension. 2003;41:1136-1142.
30. Hong F, Lee J, Song JW, Lee SJ, Ahn H, Cho JJ, Ha J, Kim SS. Cyclosporin A blocks muscle differentiation by inducing oxidative stress and inhibiting the peptidyl-prolyl-cis-trans isomerase activity of cyclophilin A: cyclophilin A protects myoblasts from cyclosporine A-induced cytotoxicity. FASEB J. 2002;16:1633-1635.
31. Demeule M, Laplante A, Sepehr-Arae A, Murphy GM, Wenger RM, Beliveau R. Association of cyclophilin A with renal brush border membranes: redistribution by Cyclosporin A. Kidney Int. 2000;57:1590-1598.
32. Harrison RK, Stein RL. Substrate specificities of the peptidyl prolyl cis-trans isomerase activity of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes. Biochemistry. 1990;29:3813-3816.
33. Wedel B, Foster DC, Miller DE, Garbers DL. A mutation of the atrial natriuretic peptide (guanylyl cyclase-A) receptor results in a constitutively hyperactive enzyme. Proc Natl Acad Sci U S A. 1997;94:459-462.