-
1
-
-
85031639498
-
Identification of a putative gating particle within the R domain for the CFTR chloride channel
-
Abstr.
-
Adams, L. M., J. Zhao, P. B. Davis, and J. Ma. 1998. Identification of a putative gating particle within the R domain for the CFTR chloride channel. Pediatr. Pulmonol. Suppl. 17:199n. (Abstr.).
-
(1998)
Pediatr. Pulmonol. Suppl.
, vol.17
-
-
Adams, L.M.1
Zhao, J.2
Davis, P.B.3
Ma, J.4
-
2
-
-
0025863209
-
Generation of cAMP-activated chloride currents by expression of CFTR
-
Anderson, M. P., D. P. Rich, R. J. Gregory, A. E. Smith, and M. J. Welsh. 1991. Generation of cAMP-activated chloride currents by expression of CFTR. Science. 251:679-682.
-
(1991)
Science
, vol.251
, pp. 679-682
-
-
Anderson, M.P.1
Rich, D.P.2
Gregory, R.J.3
Smith, A.E.4
Welsh, M.J.5
-
3
-
-
0029810468
-
Applications of gene therapy to the CNS
-
Blomer, U., L. Naldini, I. M. Verma, D. Trono, and F. H. Gage. 1996. Applications of gene therapy to the CNS. Hum. Mol. Genet. 5:1397-1404.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1397-1404
-
-
Blomer, U.1
Naldini, L.2
Verma, I.M.3
Trono, D.4
Gage, F.H.5
-
4
-
-
0028906612
-
The two nucleotide binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity
-
Carson, M. R., S. M. Travis, and M. J. Welsh. 1995. The two nucleotide binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity. J. Biol. Chem. 270:1711-1717.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 1711-1717
-
-
Carson, M.R.1
Travis, S.M.2
Welsh, M.J.3
-
5
-
-
0025987020
-
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel
-
Cheng, S. H., D. P. Rich, J. Marshall, R. J. Gregory, M. J. Welsh, and A. E. Smith, 1991. Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel. Cell. 66: 1027-1036.
-
(1991)
Cell
, vol.66
, pp. 1027-1036
-
-
Cheng, S.H.1
Rich, D.P.2
Marshall, J.3
Gregory, R.J.4
Welsh, M.J.5
Smith, A.E.6
-
6
-
-
0030774895
-
Covalent modification of the regulatory domain irreversibly stimulates cystic fibrosis transmembrane conductance regulator
-
Gotten, J. F., and M. J. Welsh. 1997. Covalent modification of the regulatory domain irreversibly stimulates cystic fibrosis transmembrane conductance regulator. J. Biol Chem. 272:25617-25622.
-
(1997)
J. Biol Chem.
, vol.272
, pp. 25617-25622
-
-
Gotten, J.F.1
Welsh, M.J.2
-
7
-
-
0343937834
-
Negative regulation of CFTR chloride channel gating through R-domain serine 768
-
Abstr.
-
Csanady, L., K. W. Chan, B. B. Angel, A. C. Nairn, and D. C. Gadsby. 1998. Negative regulation of CFTR chloride channel gating through R-domain serine 768. Pediatr. Pulmonol. Suppl. 17:205a. (Abstr.).
-
(1998)
Pediatr. Pulmonol. Suppl.
, vol.17
-
-
Csanady, L.1
Chan, K.W.2
Angel, B.B.3
Nairn, A.C.4
Gadsby, D.C.5
-
8
-
-
0028328645
-
Phosphorylation by cAMP-dependent protein kinase causes a conformational change in the R domain of the cystic fibrosis transmembrane conductance regulator
-
Dulhanty, A. M., and J. R. Riordan. 1994. Phosphorylation by cAMP-dependent protein kinase causes a conformational change in the R domain of the cystic fibrosis transmembrane conductance regulator. Biochemistry. 33:4072-4079.
-
(1994)
Biochemistry
, vol.33
, pp. 4072-4079
-
-
Dulhanty, A.M.1
Riordan, J.R.2
-
9
-
-
0031747854
-
Regulation of CFTR by protein phosphatase 2B and protein kinase C
-
Fisher, H., B. Illek, and T. E. Machen. 1998. Regulation of CFTR by protein phosphatase 2B and protein kinase C. Pflugers Arch-Eur. J. Physiol. 436:175-181.
-
(1998)
Pflugers Arch-Eur. J. Physiol.
, vol.436
, pp. 175-181
-
-
Fisher, H.1
Illek, B.2
Machen, T.E.3
-
10
-
-
0027938084
-
Regulation of CFTR channel gating
-
Gadsby, C. D., and A. C. Nairn. 1994. Regulation of CFTR channel gating. TIBS 19:513-518.
-
(1994)
TIBS
, vol.19
, pp. 513-518
-
-
Gadsby, C.D.1
Nairn, A.C.2
-
11
-
-
0027967986
-
Inefficient gene transfer by adenovirus vector to cyclic fibrosis airway epithelia of mice and humans
-
Grubb, B. R., R. J. Pickles, H. He, J. R. Yankaskas, R. N. Vick, J. F. Engelhardt, J. M. Wilson, L. G. Johnson, and R. C. Boucher. 1994. Inefficient gene transfer by adenovirus vector to cyclic fibrosis airway epithelia of mice and humans. Nature. 371:802-806.
-
(1994)
Nature
, vol.371
, pp. 802-806
-
-
Grubb, B.R.1
Pickles, R.J.2
He, H.3
Yankaskas, J.R.4
Vick, R.N.5
Engelhardt, J.F.6
Wilson, J.M.7
Johnson, L.G.8
Boucher, R.C.9
-
12
-
-
0025373627
-
Substrate specificities of the peptidyl prolyl cis-trans isomerase activity of cyclophilin and FK-506 binding protein: Evidence for the existence of a family of distinct enzymes
-
Harrison, R. K., and R. L. Stein. 1990. Substrate specificities of the peptidyl prolyl cis-trans isomerase activity of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes. Biochemistry. 29:3813-38160.
-
(1990)
Biochemistry
, vol.29
, pp. 3813-38160
-
-
Harrison, R.K.1
Stein, R.L.2
-
13
-
-
0031686496
-
What we know and what we do not know about cystic fibrosis transmembrane conductance regulator
-
Ma, J., and P. B. Davis. 1998. What we know and what we do not know about cystic fibrosis transmembrane conductance regulator. Clin. Chest Med 19:459-471.
-
(1998)
Clin. Chest Med
, vol.19
, pp. 459-471
-
-
Ma, J.1
Davis, P.B.2
-
14
-
-
0029871744
-
Phosphorylation-dependent block of cystic fibrosis transmembrane conductance regulator chloride channel by exogenous R domain protein
-
Ma, J., J. E. Tasch, T. Tao, J. Zhao, J. Xie, M. L. Drumm, and P. B. Davis. 1995. Phosphorylation-dependent block of cystic fibrosis transmembrane conductance regulator chloride channel by exogenous R domain protein. J. Biol. Chem. 271:7351-7356.
-
(1995)
J. Biol. Chem.
, vol.271
, pp. 7351-7356
-
-
Ma, J.1
Tasch, J.E.2
Tao, T.3
Zhao, J.4
Xie, J.5
Drumm, M.L.6
Davis, P.B.7
-
15
-
-
0030836234
-
Function of the R-domain in the CFTR chloride channel
-
Ma, J., J. Zhao, M. L. Drumm, J. Xie, and P. B. Davis. 1997. Function of the R-domain in the CFTR chloride channel. J. Biol. Chem. 272: 28133-28141.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28133-28141
-
-
Ma, J.1
Zhao, J.2
Drumm, M.L.3
Xie, J.4
Davis, P.B.5
-
16
-
-
0026681083
-
Phosphorylation of the cystic fibrosis transmembrane conductance regulator
-
Picciotto, M. R., J. A. Cohn, G. Bertuzzi, P. Greengard, and A. C. Nairn. 1992. Phosphorylation of the cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 267:12742-12752.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 12742-12752
-
-
Picciotto, M.R.1
Cohn, J.A.2
Bertuzzi, G.3
Greengard, P.4
Nairn, A.C.5
-
17
-
-
0027171978
-
Regulation of the cystic fibrosis transmembrane conductance regulator chloride channel by negative charge in the R domain
-
Rich, D. P., H. A. Berger, S. H. Cheng. S. M. Travis, M. Saxena, A. E. Smith, and M. J. Welsh. 1993a. Regulation of the cystic fibrosis transmembrane conductance regulator chloride channel by negative charge in the R domain. J. Biol. Chem. 268:20259-20267.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 20259-20267
-
-
Rich, D.P.1
Berger, H.A.2
Cheng, S.H.3
Travis, S.M.4
Saxena, M.5
Smith, A.E.6
Welsh, M.J.7
-
18
-
-
0025744023
-
Effect of deleting the R domain on CFTR-generated channels
-
Rich, D. P., R. J. Gregory, M. P. Anderson, P. Manavalan, A. E. Smith, and M. J. Welsh. 1991. Effect of deleting the R domain on CFTR-generated channels. Science. 253:205-207.
-
(1991)
Science
, vol.253
, pp. 205-207
-
-
Rich, D.P.1
Gregory, R.J.2
Anderson, M.P.3
Manavalan, P.4
Smith, A.E.5
Welsh, M.J.6
-
19
-
-
0027133280
-
Effect of deletion mutations on the function of CFTR chloride channels
-
Rich, D. P., R. J. Gregory, S. H. Cheng, A. E. Smith, and M. J. Welsh. 1993b. Effect of deletion mutations on the function of CFTR chloride channels. Receptors and Channels. 1:221-232.
-
(1993)
Receptors and Channels
, vol.1
, pp. 221-232
-
-
Rich, D.P.1
Gregory, R.J.2
Cheng, S.H.3
Smith, A.E.4
Welsh, M.J.5
-
20
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
Riordan, J. R., J. M. Rommens, B.-S. Kerem, N. Alon, R. Rozmahel, Z Grzelczak, J. Zielenski, S. Lok, N. Plavsic, J.-L. Chou, M. L. Drumm, M. C. Iannuzzi, F . S. Collins, and L. C. Tsui. 1989. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science. 245:1066-1073.
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.-S.3
Alon, N.4
Rozmahel, R.5
Grzelczak, Z.6
Zielenski, J.7
Lok, S.8
Plavsic, N.9
Chou, J.-L.10
Drumm, M.L.11
Iannuzzi, M.C.12
Collins, F.S.13
Tsui, L.C.14
-
21
-
-
0028590166
-
Increasing expression of the normal human CFTR cDNA in cystic fibrosis epithelial cells results in a progressive increase in the level of CFTR protein expression, but a limit on the level of cAMP-stimulated chloride secretion
-
Rosenfeld, M. A., S. J. Rosenfeld, C. Danel, T. C. Banks, and R. G. Crystal. 1994. Increasing expression of the normal human CFTR cDNA in cystic fibrosis epithelial cells results in a progressive increase in the level of CFTR protein expression, but a limit on the level of cAMP-stimulated chloride secretion. Hum. Gene. Ther. 5:1121-1129.
-
(1994)
Hum. Gene. Ther.
, vol.5
, pp. 1121-1129
-
-
Rosenfeld, M.A.1
Rosenfeld, S.J.2
Danel, C.3
Banks, T.C.4
Crystal, R.G.5
-
22
-
-
0029910820
-
Cytoplasmic loop three of cystic fibrosis transmembrane conductance regulator contributes to regulation of chloride channel activity
-
Seibert, F S., P. Linsdell, T. W. Loo, J. W. Hanrahan, J. R. Riordan, and D. M. Clarke. 1996. Cytoplasmic loop three of cystic fibrosis transmembrane conductance regulator contributes to regulation of chloride channel activity. J. Biol. Chem. 271:27493-27499.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27493-27499
-
-
Seibert, F.S.1
Linsdell, P.2
Loo, T.W.3
Hanrahan, J.W.4
Riordan, J.R.5
Clarke, D.M.6
-
23
-
-
0028223850
-
The amino-terminal portion of CFTR forms a regulated chloride channel
-
Sheppard, D. N., L. S. Ostedgaard, D. P. Rich, and M. J. Welsh. 1994. The amino-terminal portion of CFTR forms a regulated chloride channel. Cell. 76:1091-1098.
-
(1994)
Cell
, vol.76
, pp. 1091-1098
-
-
Sheppard, D.N.1
Ostedgaard, L.S.2
Rich, D.P.3
Welsh, M.J.4
-
24
-
-
0028929909
-
Mechanism of dysfunction of two nucleotide binding domain mutations in cystic fibrosis transmembrane conductance regulator that are associated with pancreatic sufficiency
-
Sheppard, D. N., L. S. Ostedgaard, M. C. Winter, and M. J. Welsh. 1996a. Mechanism of dysfunction of two nucleotide binding domain mutations in cystic fibrosis transmembrane conductance regulator that are associated with pancreatic sufficiency. EMBO J. 14:876-883.
-
(1996)
EMBO J.
, vol.14
, pp. 876-883
-
-
Sheppard, D.N.1
Ostedgaard, L.S.2
Winter, M.C.3
Welsh, M.J.4
-
25
-
-
15844397666
-
Contribution of proline residues in the membrane-spanning domains of cystic fibrosis transmembrane conductance regulator to chloride channel function
-
Sheppard, D. N., S. M. Travis, H. Ishihara, and M. J. Welsh. 1996b. Contribution of proline residues in the membrane-spanning domains of cystic fibrosis transmembrane conductance regulator to chloride channel function. J. Biol. Chem. 271:14995-15001.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 14995-15001
-
-
Sheppard, D.N.1
Travis, S.M.2
Ishihara, H.3
Welsh, M.J.4
-
26
-
-
0030928619
-
Gene therapy: Promises, problems and prospects
-
Verma, I. M., and N. Somia. 1997. Gene therapy: promises, problems and prospects. Nature. 389:239-242.
-
(1997)
Nature
, vol.389
, pp. 239-242
-
-
Verma, I.M.1
Somia, N.2
-
27
-
-
0030931648
-
Stimulation of CFTR activity by its phosphorylated R domain
-
Winter, M. C., and M. J. Welsh. 1997. Stimulation of CFTR activity by its phosphorylated R domain. Nature. 389:294-296.
-
(1997)
Nature
, vol.389
, pp. 294-296
-
-
Winter, M.C.1
Welsh, M.J.2
-
28
-
-
0028858490
-
Intracellular loop between transmembrane segments IV and V of cystic fibrosis transmembrane conductance regulator is involved in regulation of chloride channel conductance state
-
Xie, J., M. L. Drumm, J. Ma, and P. B. Davis. 1995. Intracellular loop between transmembrane segments IV and V of cystic fibrosis transmembrane conductance regulator is involved in regulation of chloride channel conductance state. J. Biol. Chem. 270:28084-28091.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28084-28091
-
-
Xie, J.1
Drumm, M.L.2
Ma, J.3
Davis, P.B.4
-
29
-
-
85031642210
-
Regulation of CFTR chloride channel by charges of the PKA phosphorylation sites in the R domain
-
Abstr.
-
Xie, J., M. L. Drumm, J. Ma, and P. B. Davis. 1997. Regulation of CFTR chloride channel by charges of the PKA phosphorylation sites in the R domain. Pediatr. Pulmonol. Suppl. 16:220a. (Abstr.).
-
(1997)
Pediatr. Pulmonol. Suppl.
, vol.16
-
-
Xie, J.1
Drumm, M.L.2
Ma, J.3
Davis, P.B.4
-
30
-
-
0029770050
-
Human epithelial cystic fibrosis transmembrane conductance regulator without Exon5 maintains partial chloride channel function in intracellular membranes
-
Xie, J., M. L. Drumm, J. Zhao, J. Ma, and P. B. Davis. 1996. Human epithelial cystic fibrosis transmembrane conductance regulator without Exon5 maintains partial chloride channel function in intracellular membranes. Biophys. J. 71:3148-3156.
-
(1996)
Biophys. J.
, vol.71
, pp. 3148-3156
-
-
Xie, J.1
Drumm, M.L.2
Zhao, J.3
Ma, J.4
Davis, P.B.5
|