메뉴 건너뛰기




Volumn 78, Issue 3, 2000, Pages 1293-1305

Conformation, independent of charge, in the R domain affects cystic fibrosis transmembrane conductance regulator channel openings

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNEL; CYCLOPHILIN A; ISOMERASE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

EID: 0034058398     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(00)76685-9     Document Type: Article
Times cited : (16)

References (30)
  • 1
    • 85031639498 scopus 로고    scopus 로고
    • Identification of a putative gating particle within the R domain for the CFTR chloride channel
    • Abstr.
    • Adams, L. M., J. Zhao, P. B. Davis, and J. Ma. 1998. Identification of a putative gating particle within the R domain for the CFTR chloride channel. Pediatr. Pulmonol. Suppl. 17:199n. (Abstr.).
    • (1998) Pediatr. Pulmonol. Suppl. , vol.17
    • Adams, L.M.1    Zhao, J.2    Davis, P.B.3    Ma, J.4
  • 2
    • 0025863209 scopus 로고
    • Generation of cAMP-activated chloride currents by expression of CFTR
    • Anderson, M. P., D. P. Rich, R. J. Gregory, A. E. Smith, and M. J. Welsh. 1991. Generation of cAMP-activated chloride currents by expression of CFTR. Science. 251:679-682.
    • (1991) Science , vol.251 , pp. 679-682
    • Anderson, M.P.1    Rich, D.P.2    Gregory, R.J.3    Smith, A.E.4    Welsh, M.J.5
  • 4
    • 0028906612 scopus 로고
    • The two nucleotide binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity
    • Carson, M. R., S. M. Travis, and M. J. Welsh. 1995. The two nucleotide binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity. J. Biol. Chem. 270:1711-1717.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1711-1717
    • Carson, M.R.1    Travis, S.M.2    Welsh, M.J.3
  • 5
    • 0025987020 scopus 로고
    • Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel
    • Cheng, S. H., D. P. Rich, J. Marshall, R. J. Gregory, M. J. Welsh, and A. E. Smith, 1991. Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel. Cell. 66: 1027-1036.
    • (1991) Cell , vol.66 , pp. 1027-1036
    • Cheng, S.H.1    Rich, D.P.2    Marshall, J.3    Gregory, R.J.4    Welsh, M.J.5    Smith, A.E.6
  • 6
    • 0030774895 scopus 로고    scopus 로고
    • Covalent modification of the regulatory domain irreversibly stimulates cystic fibrosis transmembrane conductance regulator
    • Gotten, J. F., and M. J. Welsh. 1997. Covalent modification of the regulatory domain irreversibly stimulates cystic fibrosis transmembrane conductance regulator. J. Biol Chem. 272:25617-25622.
    • (1997) J. Biol Chem. , vol.272 , pp. 25617-25622
    • Gotten, J.F.1    Welsh, M.J.2
  • 7
  • 8
    • 0028328645 scopus 로고
    • Phosphorylation by cAMP-dependent protein kinase causes a conformational change in the R domain of the cystic fibrosis transmembrane conductance regulator
    • Dulhanty, A. M., and J. R. Riordan. 1994. Phosphorylation by cAMP-dependent protein kinase causes a conformational change in the R domain of the cystic fibrosis transmembrane conductance regulator. Biochemistry. 33:4072-4079.
    • (1994) Biochemistry , vol.33 , pp. 4072-4079
    • Dulhanty, A.M.1    Riordan, J.R.2
  • 9
    • 0031747854 scopus 로고    scopus 로고
    • Regulation of CFTR by protein phosphatase 2B and protein kinase C
    • Fisher, H., B. Illek, and T. E. Machen. 1998. Regulation of CFTR by protein phosphatase 2B and protein kinase C. Pflugers Arch-Eur. J. Physiol. 436:175-181.
    • (1998) Pflugers Arch-Eur. J. Physiol. , vol.436 , pp. 175-181
    • Fisher, H.1    Illek, B.2    Machen, T.E.3
  • 10
    • 0027938084 scopus 로고
    • Regulation of CFTR channel gating
    • Gadsby, C. D., and A. C. Nairn. 1994. Regulation of CFTR channel gating. TIBS 19:513-518.
    • (1994) TIBS , vol.19 , pp. 513-518
    • Gadsby, C.D.1    Nairn, A.C.2
  • 12
    • 0025373627 scopus 로고
    • Substrate specificities of the peptidyl prolyl cis-trans isomerase activity of cyclophilin and FK-506 binding protein: Evidence for the existence of a family of distinct enzymes
    • Harrison, R. K., and R. L. Stein. 1990. Substrate specificities of the peptidyl prolyl cis-trans isomerase activity of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes. Biochemistry. 29:3813-38160.
    • (1990) Biochemistry , vol.29 , pp. 3813-38160
    • Harrison, R.K.1    Stein, R.L.2
  • 13
    • 0031686496 scopus 로고    scopus 로고
    • What we know and what we do not know about cystic fibrosis transmembrane conductance regulator
    • Ma, J., and P. B. Davis. 1998. What we know and what we do not know about cystic fibrosis transmembrane conductance regulator. Clin. Chest Med 19:459-471.
    • (1998) Clin. Chest Med , vol.19 , pp. 459-471
    • Ma, J.1    Davis, P.B.2
  • 14
    • 0029871744 scopus 로고
    • Phosphorylation-dependent block of cystic fibrosis transmembrane conductance regulator chloride channel by exogenous R domain protein
    • Ma, J., J. E. Tasch, T. Tao, J. Zhao, J. Xie, M. L. Drumm, and P. B. Davis. 1995. Phosphorylation-dependent block of cystic fibrosis transmembrane conductance regulator chloride channel by exogenous R domain protein. J. Biol. Chem. 271:7351-7356.
    • (1995) J. Biol. Chem. , vol.271 , pp. 7351-7356
    • Ma, J.1    Tasch, J.E.2    Tao, T.3    Zhao, J.4    Xie, J.5    Drumm, M.L.6    Davis, P.B.7
  • 15
    • 0030836234 scopus 로고    scopus 로고
    • Function of the R-domain in the CFTR chloride channel
    • Ma, J., J. Zhao, M. L. Drumm, J. Xie, and P. B. Davis. 1997. Function of the R-domain in the CFTR chloride channel. J. Biol. Chem. 272: 28133-28141.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28133-28141
    • Ma, J.1    Zhao, J.2    Drumm, M.L.3    Xie, J.4    Davis, P.B.5
  • 16
    • 0026681083 scopus 로고
    • Phosphorylation of the cystic fibrosis transmembrane conductance regulator
    • Picciotto, M. R., J. A. Cohn, G. Bertuzzi, P. Greengard, and A. C. Nairn. 1992. Phosphorylation of the cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 267:12742-12752.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12742-12752
    • Picciotto, M.R.1    Cohn, J.A.2    Bertuzzi, G.3    Greengard, P.4    Nairn, A.C.5
  • 17
    • 0027171978 scopus 로고
    • Regulation of the cystic fibrosis transmembrane conductance regulator chloride channel by negative charge in the R domain
    • Rich, D. P., H. A. Berger, S. H. Cheng. S. M. Travis, M. Saxena, A. E. Smith, and M. J. Welsh. 1993a. Regulation of the cystic fibrosis transmembrane conductance regulator chloride channel by negative charge in the R domain. J. Biol. Chem. 268:20259-20267.
    • (1993) J. Biol. Chem. , vol.268 , pp. 20259-20267
    • Rich, D.P.1    Berger, H.A.2    Cheng, S.H.3    Travis, S.M.4    Saxena, M.5    Smith, A.E.6    Welsh, M.J.7
  • 21
    • 0028590166 scopus 로고
    • Increasing expression of the normal human CFTR cDNA in cystic fibrosis epithelial cells results in a progressive increase in the level of CFTR protein expression, but a limit on the level of cAMP-stimulated chloride secretion
    • Rosenfeld, M. A., S. J. Rosenfeld, C. Danel, T. C. Banks, and R. G. Crystal. 1994. Increasing expression of the normal human CFTR cDNA in cystic fibrosis epithelial cells results in a progressive increase in the level of CFTR protein expression, but a limit on the level of cAMP-stimulated chloride secretion. Hum. Gene. Ther. 5:1121-1129.
    • (1994) Hum. Gene. Ther. , vol.5 , pp. 1121-1129
    • Rosenfeld, M.A.1    Rosenfeld, S.J.2    Danel, C.3    Banks, T.C.4    Crystal, R.G.5
  • 22
    • 0029910820 scopus 로고    scopus 로고
    • Cytoplasmic loop three of cystic fibrosis transmembrane conductance regulator contributes to regulation of chloride channel activity
    • Seibert, F S., P. Linsdell, T. W. Loo, J. W. Hanrahan, J. R. Riordan, and D. M. Clarke. 1996. Cytoplasmic loop three of cystic fibrosis transmembrane conductance regulator contributes to regulation of chloride channel activity. J. Biol. Chem. 271:27493-27499.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27493-27499
    • Seibert, F.S.1    Linsdell, P.2    Loo, T.W.3    Hanrahan, J.W.4    Riordan, J.R.5    Clarke, D.M.6
  • 23
    • 0028223850 scopus 로고
    • The amino-terminal portion of CFTR forms a regulated chloride channel
    • Sheppard, D. N., L. S. Ostedgaard, D. P. Rich, and M. J. Welsh. 1994. The amino-terminal portion of CFTR forms a regulated chloride channel. Cell. 76:1091-1098.
    • (1994) Cell , vol.76 , pp. 1091-1098
    • Sheppard, D.N.1    Ostedgaard, L.S.2    Rich, D.P.3    Welsh, M.J.4
  • 24
    • 0028929909 scopus 로고    scopus 로고
    • Mechanism of dysfunction of two nucleotide binding domain mutations in cystic fibrosis transmembrane conductance regulator that are associated with pancreatic sufficiency
    • Sheppard, D. N., L. S. Ostedgaard, M. C. Winter, and M. J. Welsh. 1996a. Mechanism of dysfunction of two nucleotide binding domain mutations in cystic fibrosis transmembrane conductance regulator that are associated with pancreatic sufficiency. EMBO J. 14:876-883.
    • (1996) EMBO J. , vol.14 , pp. 876-883
    • Sheppard, D.N.1    Ostedgaard, L.S.2    Winter, M.C.3    Welsh, M.J.4
  • 25
    • 15844397666 scopus 로고    scopus 로고
    • Contribution of proline residues in the membrane-spanning domains of cystic fibrosis transmembrane conductance regulator to chloride channel function
    • Sheppard, D. N., S. M. Travis, H. Ishihara, and M. J. Welsh. 1996b. Contribution of proline residues in the membrane-spanning domains of cystic fibrosis transmembrane conductance regulator to chloride channel function. J. Biol. Chem. 271:14995-15001.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14995-15001
    • Sheppard, D.N.1    Travis, S.M.2    Ishihara, H.3    Welsh, M.J.4
  • 26
    • 0030928619 scopus 로고    scopus 로고
    • Gene therapy: Promises, problems and prospects
    • Verma, I. M., and N. Somia. 1997. Gene therapy: promises, problems and prospects. Nature. 389:239-242.
    • (1997) Nature , vol.389 , pp. 239-242
    • Verma, I.M.1    Somia, N.2
  • 27
    • 0030931648 scopus 로고    scopus 로고
    • Stimulation of CFTR activity by its phosphorylated R domain
    • Winter, M. C., and M. J. Welsh. 1997. Stimulation of CFTR activity by its phosphorylated R domain. Nature. 389:294-296.
    • (1997) Nature , vol.389 , pp. 294-296
    • Winter, M.C.1    Welsh, M.J.2
  • 28
    • 0028858490 scopus 로고
    • Intracellular loop between transmembrane segments IV and V of cystic fibrosis transmembrane conductance regulator is involved in regulation of chloride channel conductance state
    • Xie, J., M. L. Drumm, J. Ma, and P. B. Davis. 1995. Intracellular loop between transmembrane segments IV and V of cystic fibrosis transmembrane conductance regulator is involved in regulation of chloride channel conductance state. J. Biol. Chem. 270:28084-28091.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28084-28091
    • Xie, J.1    Drumm, M.L.2    Ma, J.3    Davis, P.B.4
  • 29
    • 85031642210 scopus 로고    scopus 로고
    • Regulation of CFTR chloride channel by charges of the PKA phosphorylation sites in the R domain
    • Abstr.
    • Xie, J., M. L. Drumm, J. Ma, and P. B. Davis. 1997. Regulation of CFTR chloride channel by charges of the PKA phosphorylation sites in the R domain. Pediatr. Pulmonol. Suppl. 16:220a. (Abstr.).
    • (1997) Pediatr. Pulmonol. Suppl. , vol.16
    • Xie, J.1    Drumm, M.L.2    Ma, J.3    Davis, P.B.4
  • 30
    • 0029770050 scopus 로고    scopus 로고
    • Human epithelial cystic fibrosis transmembrane conductance regulator without Exon5 maintains partial chloride channel function in intracellular membranes
    • Xie, J., M. L. Drumm, J. Zhao, J. Ma, and P. B. Davis. 1996. Human epithelial cystic fibrosis transmembrane conductance regulator without Exon5 maintains partial chloride channel function in intracellular membranes. Biophys. J. 71:3148-3156.
    • (1996) Biophys. J. , vol.71 , pp. 3148-3156
    • Xie, J.1    Drumm, M.L.2    Zhao, J.3    Ma, J.4    Davis, P.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.