Effects of morphine on brain-stimulation reward thresholds in young and aged rats

Pharmacology Biochemistry and Behavior

Volumn 79, Issue 3, 2004, Pages 483-490

  Jha, Shivkumar H ^a   Knapp, Clifford M ^a   Kornetsky, Conan ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Brain stimulation reward; Morphine

Indexed keywords

MORPHINE; SODIUM CHLORIDE;

AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEPTH STIMULATION; CONTROLLED STUDY; DRUG EFFECT; LATERAL HYPOTHALAMUS; LIMBIC CORTEX; MALE; MEDIAL FOREBRAIN BUNDLE; NONHUMAN; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; RAT; RAT STRAIN; REWARD; SKIN ELECTRODE; SPECIES COMPARISON; STEREOTAXIC SURGERY;

AGING; ANIMALS; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MORPHINE; RATS; RATS, INBRED BN; RATS, INBRED F344; REWARD;

ANIMALIA;

EID: 9644265604     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2004.08.014     Document Type: Article

References (55)

1. T. Araki, H. Kato, K. Shuto, T. Fujiwara, and Y. Itoyama Effect of aging on dopaminergic receptors and uptake sites in the rat brain studied by receptor autoradiography J. Neurol. Sci. 148 1997 131 137
2. M. Bird, and C. Kornetsky Dissociation of the attentional and motivational effects of pimozide on the threshold for rewarding brain stimulation Neuropsychopharmacology 3 1990 33 40
3. B. Bontempi, and F.R. Sharp Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by the μ-opioid receptors in the substantia nigra and ventral tegmental area J. Neurosci. 17 1997 8596 8612
4. C.A. Crawford, and M.S. Levine Dopaminergic function in the neostriatum and nucleus accumbens of young and aged Fischer 344 rats Neurobiol. Aging 18 1997 57 66
5. G. Di Chiara Nucleus accumbens shell and core dopamine: differential role in behavior and addiction Behav. Brain Res. 136 2002 75 114
6. G. Di Chiara, and A. Imperato Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats J. Pharmacol. Exp. Ther. 244 1988 1067 1080
7. B.A. Donzanti, J.F. Hite, and B.K. Yamamoto Extracellular glutamate levels increase with age in the lateral striatum: potential involvement of presynaptic D-2 receptors Synapse 13 1993 376 382
8. C.L. Duvauchelle, S.M. Fleming, and C. Kornetsky Involvement of delta- and mu-opioid receptors in the potentiation of brain-stimulation reward Eur. J. Pharmacol. 316 1996 137 143
9. C.L. Duvauchelle, S.M. Fleming, and C. Kornetsky DAMGO and DPDPE facilitation of brain stimulation reward thresholds is blocked by the dopamine antagonist cis-flupenthixol Neuropharmacology 36 1997 1109 1114
10. G.I. Elmer, J.O. Pieper, M. Rubinstein, M.J. Low, D.K. Grandy, and R.A. Wise Failure of intravenous morphine to serve as an effective instrumental reinforcer in dopamine D2 receptor knock-out mice J. Neurosci. 22 2002 RC224
11. R.U. Esposito, and C. Kornetsky Morphine lowering of self-stimulation thresholds: lack of tolerance with long-term administration Science 195 1977 189 191
12. R.U. Esposito, W. Faulkner, and C. Kornetsky Specific modulation of brain stimulation reward by haloperidol Pharmacol. Biochem. Behav. 10 1979 937 940
13. M.N. Friedemann, and G.A. Gerhardt Regional effects of aging on dopaminergic function in the Fischer-344 rat Neurobiol. Aging 13 1992 325 332
14. S. Govonoi, R.A. Ruis, F. Battaini, and M. Tracuchi Reduced cAMP-dependent phosphorylation in striatum and nucleus accumbens of aged rats: evidence of an altered functioning of D1 dopaminoceptive neurons J. Gerontol. 43 1988 B93 B97
15. Z. Han, B.L. Kuyatt, K.A. Kochman, E.B. DeSouza, and G.S. Roth Effect of aging on concentrations of D2-receptor-containing neurons in the rat striatum Brain Res. 498 1989 299 307
16. D.L. Hoskins, T.L. Gordon, and T. Crisp The effects of aging on mu and delta opioid receptors in the spinal cord of Fischer-344 rats Brain Res. 791 1998 299 302
17. Y.I. Hser, V. Hoffman, C.E. Grella, and M.D. Anglin A 33-year follow-up of narcotics addicts Arch. Gen. Psychiatry 58 2001 503 508
18. A.K. Islam, M.L. Cooper, and R.J. Bodnar Interactions among aging, gender, and gonadectomy effects upon morphine antinociception in rats Physiol. Behav. 54 1993 45 53
19. D. Jourdan, G. Pickering, F. Marchand, J.M. Gaulier, J. Alliot, and A. Eschalier Impact of ageing on the antinociceptive effect of reference analgesics in the Lou/c rat Br. J. Pharmacol. 137 2002 813 820
20. P.W. Kalivas, and P. Duffy Dopamine regulation of extracellular glutamate in the nucleus accumbens Brain Res. 761 1997 173 177
21. H. Kametani, S. Iijima, E.L. Spangler, D.K. Ingram, and J.A. Josheph In vivo assessment of striatal dopamine release in the aged male Fischer 344 rat Neurobiol. Aging 16 1995 639 646
22. C.M. Knapp, and C. Kornetsky The effects of amfonelic acid alone and in combination with naloxone on brain-stimulation reward Pharmacol. Biochem. Behav. 32 1989 977 982
23. C.M. Knapp, and C. Kornetsky Low-dose apomorphine attenuates morphine-induced enhancement of brain stimulation reward Pharmacol. Biochem. Behav. 55 1994 87 91
24. 2 receptor agonist, lowers the threshold for rewarding brain stimulation Pharmacol. Biochem. Behav. 49 1994 901 904
25. C.M. Knapp, K. Lee, M. Foye, D.A. Ciraulo, and C. Kornetsky Additive effects of intra-accumbens infusion of the cAMP-specific phosphodiesterase inhibitor, rolipram and cocaine on brain stimulation reward Life Sci. 69 2001 1673 1682
26. Knapp CM, Crosby SJ, Kornetsky C. Morphine-induced analgesia as measured by brain-stimulation escape behavior in young and aged rats [Abstract]. The College on Problems of Drug Dependence Meeting (CPDD); 2004.
27. Knapp CM, Jha SH, Kornetsky C. Increased sensitization to morphine-induced oral sterotypy in aged rats. Pharmacol. Biochem. Behav. [in press].
28. C. Kornetsky, and G. Bain Brain-stimulation reward: a model for drug-induced euphoria M.W. Adler A. Cowan Modern Methods in Pharmacology Testing and Evaluation of Drugs of Abuse vol. 6 1990 Wiley New York 211 231
29. M.J. Lewis Age-related decline in brain stimulation reward: rejuvenation by amphetamine Exp. Aging Res. 7 1981 225 234
30. R. Maggi, P. Limonta, D. Dondi, L. Martini, and F. Piva Distribution of kappa opioid receptors in the brain of young and old male rats Life Sci. 45 1989 2085 2092
31. A. Markou, and G.F. Koob Construct validity of a self-stimulation threshold paradigm: Effects of reward and performance manipulations Physiol. Behav. 51 1 1992 111 119
32. L. Massieu, and R. Rapia Glutamate uptake impairment and neuronal damage in young and aged rats in vivo J. Neurochem. 69 1997 1151 1160
33. H.W. Matthes, R. Maldonado, F. Simonin, O. Valverde, S. Slowe, and I. Kitchen Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene Nature 383 1996 819 823
34. C.R. McLaughlin, and W.L. Dewey A comparison of the antinociceptive effects of opioid agonists in neonatal and adult rats in phasic and tonic nociceptive tests Pharmacol. Biochem. Behav. 49 1994 1017 1023
35. R.B. Messing, B.J. Vasquez, V.R. Spiehler, J.L. Martinez Jr., R.A. Jensen, and H. Rigter 3H-Dihydromorphine binding in brain regions of young and aged rats Life Sci. 26 1980 921 927
36. R.B. Messing, B.J. Vasquez, B. Samaniego, R.A. Jensen, J.L. Martinez Jr., and J.L. McGaugh Alterations in dihydromorphine binding in cerebral hemispheres of aged male rats J. Neurochem. 36 1990 784 787
37. M. Morelli, T. Mennini, A. Cagnotto, G. Toffano, and G. Di Chiara Quantitative autoradiographical analysis of the age-related modulation of dopamine D1 and D2 receptors Neuroscience 36 1990 403 410
38. T. Nabeshima, K. Yamada, T. Hayashi, T. Hasegawa, S. Ishihara, and T. Kameyama Changes in muscarinic cholinergic, PCP, GABAA, D1, and 5-HT2A receptor binding, but not in benzodiazepine receptor binding in the brains of aged rats Life Sci. 55 1994 1585 1593
39. J.L. Neisewander, A.J. Nonneman, S.A. McDougall, and M.T. Bardo Up-regulation of opiate receptors following chronic naloxone treatment in aged rats Neurobiol. Aging 10 1989 55 58
40. G. Paxinos, and C. Watson The rat brain in stereotaxic coordinates 1986 Academic Press New York
41. A. Pfeiffer, V. Brantl, A. Herz, and H.M. Emrich Psychotomimesis mediated by kappa opiate receptors Science 233 1986 774 776
42. F. Piva, R. Maggi, P. Limonta, D. Dondi, and L. Martini Decrease of mu opioid receptors in the brain and in the hypothalamus of the aged male rat Life Sci. 40 1987 391 398
43. F.E. Pontieri, G. Tanda, and G. Di Chiara Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens Proc. Natl. Acad. Sci. 92 1995 12304 12308
44. H. Rosenberg The elderly and the use of illicit drugs: sociological and epidemiological considerations Int. J. Addict. 30 1995 1925 1951
45. M.A. Smith, and J.D. Gray Age-related differences in sensitivity to the antinociceptive effects of opioids in male rats Psychopharmacology 156 2001 445 453
46. J.A. Stamford Development and ageing of the rat nigrostriatal dopamine system studied with fast cyclic voltammetry J. Neurochem. 52 1989 1582 1589
47. J.A. Stanford, C.R. Gash, and G.A. Gerhardt Aged F344 rats exhibit an increased proportion of dopamine agonist-excited striatal neurons Neurobiol. Aging 23 2002 263 270
48. Substance Abuse and Mental Health Services Administration. Results from the 2002 National Survey on Drug Use and Health: National Findings (Office of Applied Studies, NHSDA Series H-22, DHHS Publication No. SMA 03-3836). Rockville, MD; 2003.
49. G.E. Vaillant A 20-year follow-up of New York narcotic addicts Arch. Gen. Psychiatry 29 1973 237 241
50. J.T. Van Crugten, A.A. Somogyi, R.L. Nation, and G. Reynolds The effect of old age on the disposition and antinociceptive response of morphine and morphine-6 beta-glucuronide in the rat Pain 71 1997 199 205
51. C. Winick Maturing out of narcotic addiction Bull. Narc. 14 1962 1 7
52. D.M. Yurek, S.B. Hipkens, M.A. Hebert, D.M. Gash, and G.A. Gerhardt Age-related decline in striatal dopamine release and motoric function in brown Norway/Fischer 344 hybrid rats Brain Res. 791 2001 246 256
53. Z.B. You, Y.Q. Chen, and R.A. Wise Dopamine and glutamate release in the nucleus accumbens and ventral tegmental area of rat following lateral hypothalamic self-stimulation Neuroscience 107 2001 629 639
54. L. Zhang, and G.S. Roth The effect of aging on rat striatal D1 receptor mRNA-containing neurons Neurobiol. Aging 18 1997 251 255
55. L. Zhang, A. Ravipati, J. Joseph, and G.S. Roth Aging-related changes in rat striatal D2 receptor mRNA-containing neurons: a quantitative nonradioactive in situ hybridization study J. Neurosci. 15 1995 1735 1740