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3042772008
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Primitive roles for inhibitory interneurons in developing frog spinal cord
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W.C. Li, S. Higashijima, D.M. Parry, A. Roberts, and S.R. Soffe Primitive roles for inhibitory interneurons in developing frog spinal cord J Neurosci 24 2004 5840 5848 This beautiful study explores the physiological roles of engrailed positive neurons in frog tadpoles and shows that this transcription factor marks a multifunctional cell type that might represent the evolutionary precursor of well-studied interneurons such as Renshaw cells in mammals. This work exemplifies how the essential functional roles of neurons and their evolutionary specializations can be uncovered through a combination of developmental and functional information.
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(2004)
J Neurosci
, vol.24
, pp. 5840-5848
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Li, W.C.1
Higashijima, S.2
Parry, D.M.3
Roberts, A.4
Soffe, S.R.5
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